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A Simple Proof of Dieudonn-Manin Classification Theorem

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Acta Mathematica Sinica,English Series 2012年第8期28卷 1553-1574页

作者： yi wen ding yi OUYANG Wu wen-Tsun Key Laboratory of Mathematics University of Science and Techonology of ChinaChinese Academy of SciencesHefei 230026P.R.China School of Mathematics University of Science and Technology of ChinaHefei 230026P.R.China

The Dieudonne Manin classification theorem on φ-modules （φ-isocrystals） over a perfect field plays a very important role in p-adic Hodge theory. In this note, in a more general setting we give a new proof of this result, and in the course of the proof, we also give an explicit construction of the Harder Narasimhan filtration of a φ-module.

关键词： φ-Module strict ring Dieudonne Manin theorem Harder-Narasimhan filtration

Theoretical Simulations of Irradiation-Induced Sputtering at Tungsten Surface

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Chinese Journal of Chemical Physics 2017年第1期30卷 77-82,I0002页

作者： Xue-min Hua Hai-yan He wen-yi ding Ru ding Jun-ling Chen Bi-cai Pan Key Laboratory of Strongly-Coupled Quantum Matter Physics Department of Physics and Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of China Hefei 230025 China Institute of Plasma Physics Chinese Academy of Sciences Hefei 230031 China

The irradiation-induced sputtering and the structural damage at tungsten surface are investigated by using molecular dynamics simulations at the level of quantum mechanics. Our simulations indicate that the sputtered atoms appear when the energy of incident primary knock-on atom （PKA） is more than 200 eV and the incident angle of the PKA is larger than 65°. Meanwhile, the irradiation-induced vacancies are less when the incident angle of PKA is in the range of 45°-65°. So, the optimum incident angles of PKA are suggested to reduce the irradiation-induced damage of the W surface. Furthermore, we find that the interstitials contained in the systems accelerate the sputtering whereas the intrinsic vacancies suppress the sputtering when the PKA is near the defects.

关键词： Sputtering W surface Plasma facing material Tight-binding molecular dynamics simulations

An experimental study on effects of temperature gradient on microstructure of a 308L stainless steel manufactured by directed energy deposition

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Journal of Iron and Steel Research International 2024年第8期31卷 2031-2040页

作者： Ting Dai De-yu Gu Yu-wen Qiu Wei Guo Hui ding yi-wei Sun School of Materials Science and Engineering Jiangsu Key Laboratory of Advanced Metallic MaterialsSoutheast UniversityNanjing 211189JiangsuChina

The effect of spatial temperature gradient on the microstructural evolution of a 308L stainless steel during the directed energy deposition(DED)process was experimentally investigated.A novel cooling system was designed and incorporated to a DED system in order to control the temperature gradient along the deposition direction during *** deposition,the workpiece was placed on a lifting platform,and as the deposition process proceeded,the platform and workpiece were gradually lowered into cooling water so that the temperature gradient along the deposition direction could be controlled and maintained stable during the deposition *** microstructure characterization results indicated that a deposition strategy with higher G and G/R values(where G is temperature gradient and R is solidification rate)produced finer cellular grains that were better aligned with the deposition direction,while a deposition strategy with lower G and G/R values produced columnar grains with larger primary arm spacing and less aligned with the deposition direction.

关键词： Additive manufacturing Directed energy deposition Stainless steel Microstructure Temperature gradient

NUMERICAL SIMULATION AND ANALYSIS ON THE HEMODYNAMICS OF AN ELASTIC ANEURYSM

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Journal of Hydrodynamics 2008年第2期20卷 216-224页

作者： ZHAO Jun-wei yiN wen-yi ding Guang-hong YANG Xin-jian SHI Wan-chao ZHANG Xiao-long Department of Mechanics and Engineering Science Fudan University Shanghai 200433 China Beijing Institute ofNeurosurgery Beijing 100050 China Huashan Hospital Affiliated to Fudan University Shanghai 200040 China

Intracranial aneurysms are pathological dilatations which endanger people＇s health. Hemodynamics is thought to be an important factor in the pathogenesis and treatment of aneurysms. To date, the bulk of investigations into hemodynamics have been conducted by making use of mathematically idealized models for rigid aneurysms and associated arteries. However the walls of aneurysms and associated arteries are elastic in vivo. This study shows the differences of the simulation between elastic and rigid wall models. The numerical simulation of elastic aneurysm model is made fi＇om a representative Digital Subtraction Angiography （DSA） image and calculated with CFD software to get the wall deformation and the velocity field. Then the results are analyzed. By comparing the simulation results of the two models from their velocity vectors and shear stress distribution, many differences can be noted. The main difference exists in the distribution of velocity magnitude at some sections, with one outlet having obviously off-center distribution for the elastic wall model. The currents of the distribution of wall shear stress along the wall of aneurysm simulated in rigid and elastic wall models were similar. But there were apparent differences between the two models on the values of wall shear stress especially at the neck of aneurysm. The off-center distribution of velocity magnitude affects the distribution of wall shear stress and the exchange of substance through the wall. The analysis demonstrated clearly that the results of 2-D elastic numerical simulation were in good agreement with the clinical and pathological practice. The results of this study play an important role in the formation, growth, rupture and prognosis of an aneurysm on clinic application.

关键词： aneurysm 2-D numerical simulation elastic wall medical image

Diversity and functional analysis of Chinese bumblebee gut microbiota reveal the metabolic niche and antibiotic resistance variation of Gilliamella

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Insect Science 2021年第2期28卷 302-314页

作者： Zi-Jing Zhang Ming-Fei Huang Li-Fei Qiu Rui-Hao Song Zi-Xuan Zhang yi-wen ding Xin Zhou Xue Zhang Hao Zheng College of Food Science and Nutritional Engineering China Agricultural UniversityBeijingChina College of Plant Protection China Agricultural UniversityBeijingChina

Bumblebees play an important role in maintaining the balance of natural and agricultural ecosystems,and the characteristic gut microbiota of bumblebees exhibit significant mutualistic *** has the highest diversity of bumblebees;however,gut microbiota of Chinese bumblebees have mostly been investigated through cultureindependent ***,we analyzed the gut communities of bumblebees from Sichuan,Yunnan,and Shaanxi provinces in China through 16S ribosomal RNA amplicon sequencing and bacterial *** revealed that the bumblebees examined in this study harbored two gut enterotypes as previously reported:one is dominated by Gilliamella and Snodgrassella,and the other is distinguished by prevalent environmental *** gut compositions obviously varied among different individual *** then isolated 325 bacterial strains and the comparative genomic analysis of Gillianiella strains revealed that galactose and pectin digestion pathways were conserved in strains from bumblebees,while genes for the utilization of arabinose,mannose,xylose,and rhamnose were mostly *** two strains from the Chinese bumblebees possess the multidrug-resistant gene emrB,which is phylogenetically closely related to that from the symbionts of soil entomopathogenic *** contrast,tetracycline-resistant genes were uniquely present in three strains from the *** results illustrate the prevalence of strain-level variations in the metabolic potentials and the distributions of antibiotic-resistant genes in Chinese bumblebee gut bacteria.

关键词： antibiotic resistance bumblebee Gilliamella.,gut microbiota sugar metabolism

Sequential reactant water management by complementary multisite catalysts for surpassing platinum hydrogen evolution activity

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Nano Research 2024年第3期17卷 1232-1241页

作者： Yu Lin Defang ding Shicheng Zhu Qunlei wen Huangjingwei Li Zhen Li Youwen Liu yi Shen China Engineering Research Center of Nano-Geomaterials of Ministry of Education Faculty of Materials Science and ChemistryChina University of GeosciencesWuhan 430078China State Key Laboratory of Materials Processing and Die&Mould Technology and School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

Alkaline hydrogen evolution reaction(HER)offers a near-zero-emission approach to advance hydrogen ***,the activity limited by the multiple reaction steps involving H_(2)O molecules transfer,absorption,and activation still unqualified the thresholds of economic ***,we proposed a multisite complementary strategy that incorporates hydrophilic Mo and electrophilic V into Ni-based catalysts to divide the distinct steps on atomically dispersive sites and thus realize sequential regulation of the HER *** Isotopic labeled in situ Raman spectroscopy describes 4-coordinated hydrogen bonded H_(2)O to be free H_(2)O passing the inner Helmholtz plane in the vicinity of the catalysts under the action of hydrophilic Mo ***,potential-dependent electrochemical impedance spectroscopy(EIS)reveals that electrophilic V sites with abundant 3d empty orbitals could activate the lone-pair electrons in the free H_(2)O molecules to produce more protic hydrogen,and dimerize into H_(2) at the Ni *** the sequential management of reactive H_(2)O molecules,NiMoV oxides multisite catalysts surpass Pt/C hydrogen evolution activity(49 mV@10 mA∙cm^(-2) over 140 h).Profoundly,this study provides a tangible model to deepen the comprehension of the catalyst–electrolyte interface and create efficient catalysts for diverse reactions.

关键词： hydrogen evolution activity complementary multisite catalysts sequential reactive water management interfacial water molecules

Effects of NLRP3 Inflammasome Mediated Pyroptosis on Cardiovascular Diseases and Intervention Mechanism of Chinese Medicine

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Chinese Journal of Integrative Medicine 2024年第5期30卷 468-479页

作者： ZHONG yi LI Xin-yue LIANG Tian-jun ding Bao-zhu MA Ke-xin REN wen-xuan LIANG wen-jie College of Integrated Traditional Chinese and Western Medicine Hebei University of Chinese MedicineHebei Key Laboratory of Integrated Traditional Chinese and Western Medicine in Liver and Kidney DiseasesInstitute of Integrated Traditional Chinese and Western MedicineShijiazhuang 050200China Department of Cardiovascular Internal Medicine the Second Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi Province 332000China Graduate School Hebei Medical UniversityShijiazhuang 050017China Rural Physician College Hebei Medical UniversityShijazhuang 050017China Medical Department the First Hospital of Hebei Medical UniversityShijiazhuang 050030China

Activation of the NOD-like receptor protein 3(NLRP3)inflammasome signaling pathway is an important mechanism underlying myocardial pyroptosis and plays an important role in inflammatory damage to myocardial tissue in patients with cardiovascular diseases(CVDs),such as diabetic cardiomyopathy,ischemia/reperfusion injury,myocardial infarction,heart failure and *** RNAs(nc RNAs)are important regulatory *** Chinese medicine(CM)compounds,including their effective components,can regulate pyroptosis and exert myocardium-protecting *** mechanisms underlying this protection include inhibition of inflammasome protein expression,Toll-like receptor 4–NF-κB signal pathway activation,oxidative stress,endoplasmic reticulum stress(ERS),and mixed lineage kinase 3 expression and the regulation of silent information regulator *** NLRP3 protein is an important regulatory target for CVD prevention and treatment with *** the effects of the interventions mediated by CM and the related mechanisms provides new ideas and perspectives for CVD prevention and treatment.

关键词： pyroptosis cardiovascular diseases Chinese medicine NOD-like receptor protein 3 mechanisms

Highly Conductive Ag/pCF/MVQ Composite Rubber for Efficient Electromagnetic Interference Shielding

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Chinese Journal of Polymer Science 2024年第6期42卷 864-873页

作者： Yang Chen Xiao-Ming Shao Liang He yi-Nuo Xu Qi-Yuan Yao ding Feng wen-Cai Wang State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing100029China Key Laboratory of Beijing City for Preparation and Processing of Novel Polymer Materials Beijing University of Chemical TechnologyBeijing100029China Sino-german School of Engineering Qingdao University of Science and TechnologyQingdao266400China

In this study,flexible and highly conductive composite rubber at low filler content was successfully prepared through polydopamine-assisted electroless silver plating plus mechanical ***,carbon fibers(CF)were activated by polydopamine(PDA)to improve the surface activity by self-polymerization ***,because of the metal chelating ability of PDA,silver layer was firmly deposited on the surface of CF through a facile electroless silver plating ***,flexible silver-plated carbon fibers(Ag/pCF)silicone rubber composites prepared by mechanical *** using X-ray photoelectron spectroscopy(XPS)and X-ray diffraction(XRD),the chemical composition and crystal structure of Ag/pCF were examined,and scanning electron microscopy(SEM)was used to assess the surface morphology of the Ag/*** results showed that a uniform and dense silver layer was formed on the surface of the CF,and the conductivity of the Ag/pCF could reach 7885 S/*** was noteworthy that the composite rubber filled with only 45 phr Ag/pCF had a high electromagnetic interference shielding effectiveness(100 dB)due to the low density and high aspect ratio of Ag/*** composite rubber has excellent potential for application in the field of electromagnetic interference shielding.

关键词： Carbon fibers Polydopamine Electroless plating Silver Electromagnetic interference shielding

Pachymic acid exerts antitumor activities by modulating the Wnt/β-catenin signaling pathway via targeting PTP1B

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Asian Pacific Journal of Tropical Biomedicine 2024年第4期14卷 170-180页

作者： Hao Zhang Kun Zhu Xue-Feng Zhang yi-Hui ding Bing Zhu wen Meng Qing-Song ding Fan Zhang Department of Emergency Affiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006ZhejiangChina Department of Cardiothoracic Surgery The Third Affiliated Hospital of Qiqihar Medical CollegeQiqihar 161000HeilongjiangChina Department of Cardiothoracic Surgery The Affiliated Heilongjiang Provincial Hospital of Harbin Institute of TechnologyHarbin 150036HeilongjiangChina

Objective:To determine the inhibitory effects of pachymic acid on lung adenocarcinoma(LUAD)cells and elucidate its underlying ***:CCK-8,wound healing,Transwell,Western blot,tube formation,and immunofluorescence assays were carried out to measure the effects of various concentrations of pachymic acid on LUAD cell proliferation,metastasis,angiogenesis as well as ***,molecular docking technology was used to detect the potential targeted binding association between pachymic acid and protein tyrosine phosphatase 1B(PTP1B).Moreover,PTP1B was overexpressed in A549 cells to detect the specific mechanisms of pachymic ***:Pachymic acid suppressed LUAD cell viability,metastasis as well as angiogenesis while inducing cell *** also targeted PTP1B and lowered PTP1B ***,PTP1B overexpression reversed the effects of pachymic acid on metastasis,angiogenesis,and autophagy as well as the expression of Wnt3a andβ-catenin in LUAD ***:Pachymic acid inhibits metastasis and angiogenesis,and promotes autophagy in LUAD cells by modulating the Wnt/β-catenin signaling pathway via targeting PTP1B.

关键词： Pachymic acid Lung adenocarcinoma Protein tyrosine phosphatase 1B Wnt/β-catenin signaling pathway Metastasis Angiogenesis Autophagy