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V0405 Dra:A New Deep and Low Mass Ratio Contact Binary with Extremely Fast Decrease in the Orbital Period

Research in Astronomy and Astrophysics 2024年第6期24卷 287-293页

作者： Chao-Yue Li Lin-qiao Jiang Jie Zheng yi-Man Liu Xiao-Yu Long Min Sun Han-Lu Zhang Xiao-Man Tian School of Science Leshan Normal UniversityLeshan 614000China Center for Applied Optics Research Leshan Normal UniversityLeshan 614000China Key Laboratory of Detection and Application of Space Effect in Southwest Sichuan Leshan 614000China CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Aeronautics Shandong Jiaotong UniversityJinan 250000China

V0405 Dra is a W UMa-type binary *** on the TESS data,we have conducted an orbital period study and performed a light curve analysis for the *** orbital period study reveals that the O-C curve for V0405 Dra exhibits secular decrease at an extremely high rate of d P/dt=-2.71×10^(-6)day year^(-1),along with periodic variations characterized by an amplitude of A_(3)=0.0032 day and a period of P_(3)=1.413 *** orbital periodic change is possibly due to the light-travel time effect resulting from an additional third body in the system,for which we estimate a minimum mass of M_(3)=0.77M_(⊙).By employing the 2013 version of the Wilson-Devinney(W-D)method to synthesize a light curve,we derived photometric solutions indicating that V0405 Dra is a new deep(f=68.7%)and low-mass ratio(q=0.175)contact *** fast decrease in its orbital period is likely caused by mass transfer from the more massive primary star to the less massive secondary star,or due to angular momentum *** further mass transfer and loss of angular momentum,the binary will gradually evolve into a tighter contact configuration,eventually leading to a merger into a single star,following the evolutionary paths suggested for such deep and low mass ratio contact binaries.

关键词： (stars:)binaries(including multiple):close (stars:)binaries:eclipsing stars:individual(V0405 Dra)

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In situ synthesis of porous Pt-Pd bimetallic structures for sweat glucose biosensing using dynamic hydrogen bubble template method

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Rare Metals 2024年第7期43卷 3408-3414页

作者： yi-Wen Guo Qian-Hui Wei Fei Wei Hao Liu Hong-Bin Zhao dong Wang Hai-Ling Tu State Key Laboratory of Advanced Materials for Smart Sensing China GRINM Group Co.Ltd.Beijing 100088China Department of Advanced Electronic Materials GRIMAT Engineering Institute Co.Ltd.Beijing 101407China General Research Institute for Nonferrous Metals Beijing 100088China GRINM(Guangdong)Institute for Advanced Materials and Technology Foshan 528000China School of Chemical Engineering Northeast Electric Power UniversityJilin 132012China

For the practical application of sweat glucose biosensors,it is crucial to develop a method for modifying the working electrode with noble metals that ensures strong *** this study,we synthesized porous Pt-Pd bimetall... 详细信息

关键词： method. bubble porous

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Coordinate-wise monotonic transformations enable privacy-preserving age estimation with 3D face point cloud

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Science China(Life Sciences) 2024年第7期67卷 1489-1501页

作者： Xinyu Yang Runhan Li Xindi Yang Yong Zhou yi Liu Jing-dong J.Han School of Life Sciences Peking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology(CQB)Peking UniversityBeijing 100871China Beijing Key Lab of Traffic Data Analysis and Mining School of Computer and Information TechnologyBeijing Jiaotong UniversityBeijing 100044China Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

The human face is a valuable biomarker of aging,but the collection and use of its image raise significant privacy *** we present an approach for facial data masking that preserves age-related features using coordinate-wise monotonic *** first develop a deep learning model that estimates age directly from non-registered face point clouds with high accuracy and *** show that the model learns a highly indistinguishable mapping using faces treated with coordinate-wise monotonic transformations,indicating that the relative positioning of facial information is a low-level biomarker of facial *** visual perception tests and computational3D face verification experiments,we demonstrate that transformed faces are significantly more difficult to perceive for human but not for machines,except when only the face shape information is *** study leads to a facial data protection guideline that has the potential to broaden public access to face datasets with minimized privacy risks.

关键词： face point cloud age estimation face verification privacy coordinate-wise monotonic transformation

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Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1

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Frontiers of Medicine 2024年第1期18卷 180-191页

作者： Fang Wang Yuxing Liu yi dong Meifang Zhao Hao Huang Jieyuan Jin Liangliang Fan Rong Xiang Department of Endocrinology The Third Xiangya Hospital of Central South UniversityChangsha410013China Department of Cellular Biology School of Life SciencesKey Laboratory of Pediatric Rare DiseasesMinistry of EducationCentral South UniversityChangsha410013China

Lipin proteins including Lipin 1–3 act as transcriptional co-activators and phosphatidic acid phosphohydrolase enzymes,which play crucial roles in lipid ***,little is known about the function of Lipin3 in triglyceride(TG)***,we identified a novel mutation(NM_001301860:p.1835A>T/p.D612V)of Lipin3 in a large family with hypertriglyceridemia(HTG)and obesity through whole-exome sequencing and Sanger *** studies revealed that the novel variant altered the half-life and stability of the Lipin3 ***,we generated Lipin3 heterozygous knockout(Lipin3-heKO)mice and cultured primary hepatocytes to explore the pathophysiological roles of Lipin3 in TG *** found that Lipin3-heKO mice exhibited obvious obesity,HTG,and non-alcoholic fatty liver *** study demonstrated that the haploinsufficiency of Lipin3 in primary hepatocytes may induce the overexpression and abnormal distribution of Lipin1 in cytosol and *** increased expression of Lipin1 in cytosol may contribute to TG anabolism,and the decreased Lipin1 in nucleoplasm can reduce PGC1α,further leading to mitochondrial dysfunction and reduced TG *** study suggested that Lipin3 was a novel disease-causing gene inducing obesity and *** also established a relationship between Lipin3 and mitochondrial dysfunction.

关键词： Lipin3 Lipin1 hypertriglyceridemia obesity mitochondrial dysfunction

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Design to enhance sensing performance of ZIF-8 crystals

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Progress in Natural Science:Materials International 2024年第2期34卷 240-250页

作者： Ya-Ru Li Xiuxiu dong Shu-yi Pan Lin Luo Hong-Tao Lei Zhen-Lin Xu Guangdong Provincial Key Laboratory of Food Quality and Safety College of Food Science South China Agricultural University Key Laboratory of Modern Agricultural Equipment and Technology (Jiangsu University) Ministry of Education School of Agricultural Engineering Jiangsu University

Metal-organic frameworks（MOFs） are a large class of crystalline porous materials that composed of organic ligands and metal ions,of which zeolitic imidazolate frameworks（ZIFs） are a broad *** most wellknown ZIF-like material is ZIF-8 crystals,which have been the subject of extensive research for ***-8 crystals have been synthesized under various conditions for application in the fields of sensing,drug delivery,and *** paper provides a brief introduction to the preparation methods,formation processes,and formation mechanisms of ZIF-8 crystals in different media,and then explains the effects of different precursor conditions(type of Zn2+,ratio of raw materials,and type of solvent) on ZIF-8 crystals in terms of formation ***,current reports on the application of ZIF-8-based chemiresistive gas sensors,electrochemical,fluorescent and colorimetric sensors are also ***,ZIF-8 crystals with good catalytic properties will be obtained based on rational design for promoting the application in different fields of the sensors.

关键词： Formation mechanism Regulation Sensing performance Synthesis method ZIF-8

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Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery

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World Journal of Gastroenterology 2024年第12期30卷 1714-1726页

作者： dong Peng Zi-Wei Li Fei Liu Xu-Rui Liu Chun-yi Wang Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Previous studies have reported that low hematocrit levels indicate poor survival in patients with ovarian cancer and cervical cancer,the prognostic value of hematocrit for colorectal cancer(CRC)patients has not been *** prognostic value of red blood cell distribution width(RDW)for CRC patients was *** To investigate the impact of RDW and hematocrit on the short-term outcomes and long-term prognosis of CRC patients who underwent radical *** Patients who were diagnosed with CRC and underwent radical CRC resection between January 2011 and January 2020 at a single clinical center were *** short-term outcomes,overall survival(OS)and disease-free survival(DFS)were compared among the different *** analysis was also conducted to identify independent risk factors for OS and *** There were 4258 CRC patients who underwent radical surgery included in our study.A total of 1573 patients were in the lower RDW group and 2685 patients were in the higher RDW *** were 2166 and 2092 patients in the higher hematocrit group and lower hematocrit group,*** in the higher RDW group had more intraoperative blood loss(P<0.01)and more overall complications(P<0.01)than did those in the lower RDW ***,patients in the lower hematocrit group had more intraoperative blood loss(P=0.012),longer hospital stay(P=0.016)and overall complications(P<0.01)than did those in the higher hematocrit *** higher RDW group had a worse OS and DFS than did the lower RDW group for tumor node metastasis(TNM)stage I(OS,P<0.05;DFS,P=0.001)and stage II(OS,P=0.004;DFS,P=0.01)than the lower RDW group;the lower hematocrit group had worse OS and DFS for TNM stage II(OS,P<0.05;DFS,P=0.001)and stage III(OS,P=0.001;DFS,P=0.001)than did the higher hematocrit *** hematocrit was an independent risk factor for OS[P=0.017,hazard ratio(HR)=1.256,95%confidence interval(CI):1.041-1.515]and DFS(P=0.035,HR=1.194

关键词： Colorectal cancer Red blood cell distribution width Survival Short-term outcomes

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Study on improving hematopoietic function of rats with blood deficiency syndrome by Shengxuebao mixture

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Traditional Medicine Research 2024年第8期9卷 35-46页

作者： Yan Shu Hong-Na Liu Yang Zhao Jin-yi Cao Yue Chen yi qiao Hui Guo Zhi-Fu Yang College of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China Tsing Hua De Ren Xi’an Happiness Pharmaceutical Co. Ltd.Xi’an 710400China Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’an 710000China State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration National Clinical Research Center for Oral DiseasesShaanxi Engineering Research Center for Dental Materials and Advanced ManufactureDepartment of PharmacySchool of Stomatologythe Fourth Military Medical UniversityXi’an 710000China

Background:Shengxuebao mixture(SXBM)is a novel herbal drug approved by China State Food and Drug Administration for the treatment of Leukopenia and iron deficiency anemia caused by radiotherapy and ***:To explore the mechanism of SXBM in treating blood deficiency syndrome(BDS).Firstly,network pharmacology and in vivo experiments were used to screen candidate targets and important signaling pathways of SXBM,GO functional enrichment and KEGG pathway analysis were ***,a BDS rat model was established to verify the results of the analysis of network pharmacological *** and routine peripheral blood examination were *** expressions of tumor necrosis factor-α,interleukin(IL)-6,HIF-1αand NF-κB were detected by Western blot,and the expressions of IL-6,IL-1βwere detected by ***:62 bioactive components,66 potential targets and 131 signaling pathways of BDS were successfully identified by network *** docking simulation techniques showed that key targets tumor necrosis factor-α,IL-6,IL-1βcan dock well with crucial components,and the BDS-related signaling pathways HIF-1 and JAK-STAT play a vital *** combined model experiment of acetylphenylhydrazine and cyclophosphamide showed that the model group had obvious blood deficiency,and the histopathology and blood routine were effectively restored after *** findings indicate that SXBM’s therapeutic effect on BDS primarily involves the mediation of the HIF-1α/NF-κB signaling pathway and the regulation of hematopoietic factor ***:This study not only affirmed the protective properties of SXBM against BDS but also provided insights into a potential mechanism for blood replenishment in the treatment of BDS using SXBM.

关键词： network pharmacology molecular docking technology blood deficiency syndrome hematopoietic factors HIF-1α/NF-κB

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Quality assessment of friction-stir-welded aluminum alloy welds via three-dimensional force signals

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Advances in Manufacturing 2024年第1期12卷 61-75页

作者： Ji-Hong dong yi-Ming Huang Jia-Lei Zhu Wei Guan Xu-Kai Ren Huan-Wei Yu Lei Cui Beijing Institute of Petrochemical Technology Beijing102617People’s Republic of China Beijing Academy of Safety Engineering and Technology Beijing102617People’s Republic of China AVIC Manufacturing Technology Institute Beijing100024People’s Republic of China Tianjin Key Laboratory of Advanced Joining Technology School of Materials Science and EngineeringTianjin UniversityTianjin300350People’s Republic of China Shaoxing Special Equipment Testing Institute Shaoxing Key Laboratory of Special Equipment Intelligent Testing and EvaluationShaoxing312071ZhejiangPeople’s Republic of China

An online detection technology must be developed for realizing the real-time control of friction stir *** this study,the three-dimensional force exerted on a material during friction stir welding was collected synchronously and the relationship between the forces and welding quality was *** results indicated that the fluctuation period of the traverse force was equal to that of the lateral force during the stable welding *** phase difference between two horizontal forces wasπ/*** values of the horizontal forces increased with welding speed,whereas their amplitudes remained the *** proposed force model showed that the traverse and lateral forces conformed to an elliptical curve,and this result was consistent with the behavior of the measured *** variational mode decomposition was used to process the plunge *** intrinsic mode function that represented the real fluctuation in the plunge force varied at the same frequency as the spindle rotational *** tunnel defects occurred,the fluctuation period features were consistent with those obtained during normal welding,whereas the ratio parameter defined in this study increased significantly.

关键词： Friction stir welding(FSW) Three-dimensional force model Variational mode decomposition Tunnel defect

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Texture and Se vacancy optimization induces high thermoelectric performance in Bi_(2)Se_(3) flexible thin films

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Rare Metals 2024年第6期43卷 2796-2804页

作者： dong-Wei Ao Wei-Di Liu Yue-Xing Chen Fan Ma yi-Jie Gu Zhuang-Hao Zheng School of Machinery and Automation Weifang UniversityWeifang 261061China Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbane 4072Australia Shenzhen Key Laboratory of Advanced Thin Films and Applications Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong ProvinceCollege of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen518060China School of Materials Science and Engineering Inner Mongolia University of TechnologyHohhot 010051China

Bi_(2)Se_(3)-based flexible thin film with high thermoelectric performance is promising for the waste heat recovery *** this work,a novel post-selenization method is employed to prepare n-type Bi_(2)Se_(3)flexible thin films with highly textured *** strengthened texture and Se vacancy optimization can be simultaneously achieved by optimizing the selenization *** highly oriented texture leads to the increased carrier mobility and results in a high electric conductivity of~290.47 S·cm^(-1)at 623 ***,a high Seebeck coefficient(>110μW·K-1)is obtained due to the reduced carrier concentration,induced by optimizing vacancy ***,a high power factor of 3.49μW·cm^(-1)·K^(-2)at 623 K has been achieved in asprepared highly-bendable Bi_(2)Se_(3)flexible thin films selenized at 783 *** study introduces an effective post-selenization method to tune the texture structure and vacancies of Bi_(2)Se_(3)flexible thin films,and correspondingly achieves high thermoelectric performance.

关键词： Thermoelectric Bi_(2)Se_(3) Flexible thin film Post-selenization

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Self organizing optimization and phase transition in reinforcement learning minority game system

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Frontiers of physics 2024年第4期19卷 297-309页

作者： Si-Ping Zhang Jia-Qi dong Hui-Yu Zhang yi-Xuan Lü Jue Wang Zi-Gang Huang Key Laboratory of Biomedical Information Engineering of Ministry of Education Key Laboratory of Neuro-informatics&Rehabilitation Engineering of Ministry of Civil Affairsand Institute of Health and Rehabilitation ScienceSchool of Life Science and TechnologyXi’an Jiaotong UniversityXi’an 710049China Lanzhou Center for Theoretical Physics and Key Laboratory of Theoretical Physics of Gansu Province Lanzhou UniversityLanzhou 730000China

Whether the complex game system composed of a large number of artificial intelligence(AI)agents empowered with reinforcement learning can produce extremely favorable collective behaviors just through the way of agent self-exploration is a matter of practical *** this paper,we address this question by combining the typical theoretical model of resource allocation system,the minority game model,with reinforcement *** individual participating in the game is set to have a certain degree of intelligence based on reinforcement learning *** particular,we demonstrate that as AI agents gradually becomes familiar with the unknown environment and tries to provide optimal actions to maximize payoff,the whole system continues to approach the optimal state under certain parameter combinations,herding is effectively suppressed by an oscillating collective behavior which is a self-organizing pattern without any external *** interesting phenomenon is that a first-order phase transition is revealed based on some numerical results in our multi-agents system with reinforcement *** order to further understand the dynamic behavior of agent learning,we define and analyze the conversion path of belief mode,and find that the self-organizing condensation of belief modes appeared for the given trial and error rates in the AI ***,we provide a detection method for period-two oscillation collective pattern emergence based on the Kullback–Leibler divergence and give the parameter position where the period-two appears.

关键词： oscillatory evolution collective behaviors phase transition reinforcement learning minority game

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