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Long head of biceps tendon transposition for massive and irreparable rotator cuff tears:A systematic review and meta-analysis

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World Journal of Orthopedics 2023年第11期14卷 813-826页

作者： Ren-Wen Wan Zhi-Wen Luo yi-meng yang Han-Li Zhang Jia-Ni Chen Shi-yi Chen Xi-Liang Shang Department of Sports Medicine Huashan HospitalFudan UniversityShanghai 200040China

BACKGROUND Superior capsular reconstruction(SCR)with long head of biceps tendon(LHBT)transposition was developed to massive and irreparable rotator cuff tears(MIRCTs);however,the outcomes of this technique remain *** To perform a systematic review of biomechanical outcomes and a meta-analysis of clinical outcomes after LHBT transposition for *** We performed a systematic electronic database search on PubMed,EMBASE,and Cochrane *** of SCR with LHBT transposition were included according to the inclusion and exclusion *** studies were assessed for main results and *** clinical studies were evaluated for quality of *** including study characteristics,cohort demographics,and outcomes were extracted.A meta-analysis was conducted of the clinical *** According to our inclusion and exclusion criteria,a total of six biomechanical studies were identified and reported an overall improvement in subacromial contact pressures and prevention of superior humeral migration without limiting range of motion(ROM)after LHBT transposition for MIRCTs.A total of five clinical studies were included in the meta-analysis of LHBT transposition outcomes,consisting of 253 *** results indicated that compared to other surgical methods for MIRCTs,LHBT transposition had advantages of more significant improvement in ROM(forward flexion mean difference[MD]=6.54,95%confidence interval[CI]:3.07-10.01;external rotation[MD=5.15,95%CI:1.59-8.17];the acromiohumeral distance[AHD][MD=0.90,95%CI:0.21-1.59])and reducing retear rate(odds ratio=0.27,95%CI:0.15-0.48).No significant difference in American Shoulder and Elbow Surgeons score,visual analogue scale score,and University of California at Los Angles score was demonstrated between these two groups for *** In general,SCR with LHBT transposition was a reliable and economical technique for treating MIRCTs,both in terms of biomechanical and clinica

关键词： Massive and irreparable rotator cuff tears Long head of biceps tendon transposition Rotator cuff repair Superior capsular reconstruction

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Long-term Outcome of Multiple Small-diameter Drilling Decompression Combined with Hip Arthroscopy versus Drilling Alone for Early Avascular Necrosis of the Femoral Head

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Chinese Medical Journal 2017年第12期130卷 1435-1440页

作者： Ji Li Zhong-Li Li Hao Zhang Xiang-Zheng Su Ke-Tao Wang yi-meng yang Department of Orthopedics General Hospital of People's Liberation Army Beijing 100853 China

Background： Avascular necrosis of femoral head （AVNFH） typically presents in the young adults and progresses quickly without proper treatments. However, the optimum treatments for early stage of AVNFH are still controversial. This study was conducted to evaluate the therapeutic effects of multiple small-diameter drilling decompression combined with hip arthroscopy for early AVNFH compared to drilling alone. Methods： This is a nonrandomized retrospective case series study. Between April 2006 and November 2010, 60 patients （98 hips） with early stage AVNFH participated in this study. The patients underwent multiple small-diameter drilling decompression combined with hip arthroscopy in 26 cases/43 hips （Group A） or drilling decompression alone in 34 cases/55 hips （Group B）. Patients were followed up at 6, 12, and 24 weeks, and every 6 months thereafter. Radiographs were taken at every follow-up, Harris scores were recorded at the last follow-up, the paired t-test was used to compare the postoperative Harris scores. Surgery effective rate of the two groups was compared using the Chi-square test. Results： All patients were followed up for an average of 57.6 months （range： 17-108 months）. Pain relief and improvement of hip function were assessed in all patients at 6 months after the surgery. At the last follow-up, Group A had better outcome with mean Harris＇ scores improved from 68.23 ± 11.37 to 82.07 ± 2.92 （t = -7.21, P = 0.001） than Group B with mean Harris＇ scores improved from 69.46 ± 9.71 to 75.79± 4.13 （t = -9.47, P = 0.037）（significantly different： t = -2.54, P = 0.017）. The total surgery effective rate was also significantly different between Groups A and B （86.0% vs. 74.5%; Z2 = 3.69, P = 0.02）. Conclusion： For early stage of AVNFH, multiple small-diameter drilling decompression combined with hip arthroscopy is more effective than drilling decompression alone.

关键词： Avascular Necrosis of Femoral Head Core Decompression Hip Arthroscopy Long-term Outcome MultipleSmall-diameter Drill Decompression

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Hot-electron deposition and implosion mechanisms within electron shock ignition

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Chinese Physics B 2020年第10期29卷 354-362页

作者： Wan-Li Shang Xing-Sen Che Ao Sun Hua-Bing Du Guo-Hong yang Min-Xi Wei Li-Fei Hou yi-meng yang Wen-Hai Zhang Shao-Yong Tu Feng Wang Hai-En He Jia-Min yang Shao-En Jiang Bao-Han Zhang Research Center of Laser Fusion China Academy of Engineering PhysicsMianyang 621900China

A hot-electron driven scheme can be more effective than a laser-driven scheme within suitable hot-electron energy and target density. In our one-dimensional (1D) radiation hydrodynamic simulations, 20× pressure enhancement was achieved when the ignitor laser spike was replaced with a 60-keV hot-electron spike in a shock ignition target designed for the National Ignition Facility (NIF), which can lead to greater shell velocity. Higher hot-spot pressure at the deceleration phase was obtained owing to the greater shell velocity. More cold shell material is ablated into the hot spot, and it benefits the increases of the hot-spot pressure. Higher gain and a wider ignition window can be observed in the hot-electron-driven shock ignition.

关键词： shock ignition inertial confinement fusion hot electron plasma fusion

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Magneto‑Dielectric Synergy and Multiscale Hierarchical Structure Design Enable Flexible Multipurpose Microwave Absorption and Infrared Stealth Compatibility

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Nano-Micro Letters 2025年第2期17卷 401-416页

作者： Chen Li Leilei Liang Baoshan Zhang yi yang Guangbin Ji School of Electronic Science and Engineering Nanjing UniversityNanjing 210093People’s Republic of China College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Developing advanced stealth devices to cope with radar-infrared(IR)fusion detection and diverse application scenarios is increasingly demanded,which faces significant challenges due to conflicting microwave and IR cloaking mechanisms and functional integration ***,we propose a multiscale hierarchical structure design,integrating wrinkled MXene IR shielding layer and flexible Fe_(3)O_(4)@C/PDMS microwave absorption *** top wrinkled MXene layer induces the intensive diffuse reflection effect,shielding IR radiation signals while allowing microwave to pass ***,the permeable microwaves are assimilated into the bottom Fe_(3)O_(4)@C/PDMS layer via strong magneto-electric *** theoretical and experimental optimization,the assembled stealth devices realize a near-perfect stealth capability in both X-band(8–12 GHz)and long-wave infrared(8–14μm)wavelength ***,it delivers a radar cross-section reduction of−20 dB m^(2),a large apparent temperature modulation range(ΔT=70℃),and a low average IR emissivity of ***,the optimal device demonstrates exceptional curved surface conformability,self-cleaning capability(contact angle≈129°),and abrasion resistance(recovery time≈5 s).This design strategy promotes the development of multispectral stealth technology and reinforces its applicability and durability in complex and hostile environments.

关键词： Microwave absorption Radar-infrared compatible stealth Wrinkled MXene Magneto-dielectric synergy Multifunction

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Small modifications of endo-functionalized cavities lead to large changes in molecular interaction in water

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Science China Chemistry 2025年第01期 369-376页

作者： Song-meng Wang Hao Nian Yan-Fang Wang Li-Shuo Zheng Yu-Tao Zheng yi-Wei Dong Liping Huang Xiaoping Wang Wei Jiang Liu-Pan yang Department of Chemistry Southern University of Science and Technology School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal ResourcesGuangxi Normal University School of Pharmaceutical Science Hengyang Medical School University of South China

Studying molecular recognition in aqueous environments is crucial for understanding biological processes. Herein, we present a series of N-doped endo-functionalized anthracene-based cavities by introducing inward-directed pyridine units. The subtle modifications can significantly affect the binding properties of these receptors, which is similar to the mutations in biological systems. Combining theoretical calculations and molecular recognition experiments demonstrated that these “mutations” have an impact on the hydrophobicity and charge distribution of the hosts, consequently significantly influencing molecular *** is crucial for understanding the intricate mechanisms of molecular-level interactions in biological receptors.

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Exosomes:the next-generation therapeutic platform for ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1221-1235页

作者： Wenjing yin Hongyin Ma yang Qu Jiaxin Ren yingying Sun Zhen-Ni Guo yi yang Stroke Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuroscience Research Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

Current therapeutic strategies for ischemic stroke fall short of the desired objective of neurological functional ***,there is an urgent need to develop new methods for the treatment of this *** are natural cell-derived vesicles that mediate signal transduction between cells under physiological and pathological *** have low immunogenicity,good stability,high delivery efficiency,and the ability to cross the blood–brain *** physiological properties of exosomes have the potential to lead to new breakthroughs in the treatment of ischemic *** rapid development of nanotechnology has advanced the application of engineered exosomes,which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dosages *** in technology have also driven clinical translational research on *** this review,we describe the therapeutic effects of exosomes and their positive roles in current treatment strategies for ischemic stroke,including their antiinflammation,anti-apoptosis,autophagy-regulation,angiogenesis,neurogenesis,and glial scar formation reduction ***,it is worth noting that,despite their significant therapeutic potential,there remains a dearth of standardized characterization methods and efficient isolation techniques capable of producing highly purified *** optimization strategies should prioritize the exploration of suitable isolation techniques and the establishment of unified workflows to effectively harness exosomes for diagnostic or therapeutic applications in ischemic ***,our review aims to summarize our understanding of exosome-based treatment prospects in ischemic stroke and foster innovative ideas for the development of exosome-based therapies.

关键词： blood–brain barrier electroacupuncture engineering exercise exosomes ischemic stroke mesenchymal stem cells microglia neuroprotection stents

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茶渣吸附性能在茶汤保鲜中的应用

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江苏农业学报 2016年第5期32卷 1162-1170页

作者：张晶晶汤一杨梦璇浙江大学农业与生物技术学院浙江杭州310058

为探究茶渣吸附处理对茶汤的保鲜作用,检测和分析了吸附后茶汤的儿茶素含量、咖啡因含量、氨基酸含量、色度值和透光率,并与交联聚乙烯吡咯烷酮(PVPP)和木质纤维素吸附处理进行对比。结果表明:贮藏15d后3种吸附剂处理及对照之间茶汤表... 详细信息

为探究茶渣吸附处理对茶汤的保鲜作用,检测和分析了吸附后茶汤的儿茶素含量、咖啡因含量、氨基酸含量、色度值和透光率,并与交联聚乙烯吡咯烷酮(PVPP)和木质纤维素吸附处理进行对比。结果表明:贮藏15d后3种吸附剂处理及对照之间茶汤表没食子儿茶素(EGC)、儿茶素(C)、表儿茶素(EC)、表没食子儿茶素没食子酸酯(EGCG)、儿茶素总量(T-C)含量均存在极显著差异(P木质纤维素处理(324.71 mg/L)>茶渣处理(155.08 mg/L)>PVPP处理(47.52 mg/L)。对茶汤色泽的改善效果PVPP处理>茶渣处理>木质纤维素处理,茶渣处理的氨基酸含量高于其他处理,而3种处理之间透光度无显著差异。使用茶渣吸附60 min保鲜效果最好,可以在尽量保留茶汤中儿茶素的前提下,有效改善茶汤的外观品质。

关键词：茶渣吸附茶汤保鲜

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Progress of research in the application of ultrasound technology for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2823-2837页

作者： Qiuquan Cai Lianghui meng Meina Quan Ling Wang Jing Ren Chenguang Zheng Jiajia yang Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Innovation Center for Neurological Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Brain-Computer Interaction and Human-Machine Fusion Haihe Laboratory Tianjin UniversityTianjinChina Tianjin Key Laboratory of Brain Science and Neural Engineering Tianjin UniversityTianjinChina

Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive *** presence of the blood-brain barrier presents a major obstacle to the development of effective drug therapies for Alzheimer’s *** use of ultrasound as a novel physical modulation approach has garnered widespread attention in recent *** a safe and feasible therapeutic and drug-delivery method,ultrasound has shown promise in improving cognitive *** article provides a summary of the application of ultrasound technology for treating Alzheimer’s disease over the past 5 years,including standalone ultrasound treatment,ultrasound combined with microbubbles or drug therapy,and magnetic resonance imaging-guided focused ultrasound *** is placed on the benefits of introducing these treatment methods and their potential *** found that several ultrasound methods can open the blood-brain barrier and effectively alleviate amyloid-βplaque *** believe that ultrasound is an effective therapy for Alzheimer’s disease,and this review provides a theoretical basis for future ultrasound treatment methods.

关键词： Alzheimer’s disease blood-brain barrier drugs magnetic resonance imaging-guided focused ultrasound microbubbles scanning ultrasound ultrasound ultrasound stimulation

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三仁汤临床应用举隅

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光明中医 2017年第6期32卷 887-890页

作者：叶梦怡牛阳宁夏医科大学中医学院硕士研究生2014级银川750004 宁夏医科大学回医药现代化省部共建教育部共建实验室银川750004

三仁汤出自《温病条辨》,为清代医家吴鞠通创立治疗湿温病的首剂,具有清热利湿,宣畅气机之功效。临床上,结合中医学异病同治的法则,应用三仁汤分消走泄,湿解热清的作用,不仅用于治疗外感湿热病,更广泛用于治疗内伤杂病三焦湿热内阻之证... 详细信息

三仁汤出自《温病条辨》,为清代医家吴鞠通创立治疗湿温病的首剂,具有清热利湿,宣畅气机之功效。临床上,结合中医学异病同治的法则,应用三仁汤分消走泄,湿解热清的作用,不仅用于治疗外感湿热病,更广泛用于治疗内伤杂病三焦湿热内阻之证,其治疗临床各科疾病的效果俱佳。故现将三仁汤的临床应用进行总结分析,以期对提高临证水平具有启迪和指导作用。

关键词：三仁汤湿温病中医药疗法异病同治

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Efficacy,safety and treatment satisfaction of transition to a regimen of insulin degludec/aspart:A pilot study

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World Journal of Diabetes 2025年第1期16卷 65-73页

作者： Na yang Lu Lv Shu-meng Han Li-Yun He Zi-yi Li Yu-Cheng yang Fan Ping Ling-Ling Xu Wei Li Hua-Bing Zhang Yu-Xiu Li Department of Endocrinology Key Laboratory of Endocrinology of National Health CommissionPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Allergy Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment of Allergic DiseasesNational Clinical Research Center for Dermatologic and Immunologic DiseasesPeking Union Medical College HospitalChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100730China

BACKGROUND There is a lack of clinical evidence on the efficacy and safety of transitioning from a thrice-daily pre-mixed insulin or basal-prandial regimen to insulin degludec/aspart(IDegAsp)therapy,with insufficient data from the Chinese *** To demonstrate the efficacy,safety,and treatment satisfaction associated with the transition to IDegAsp in type 2 diabetes mellitus(T2DM).METHODS In this 12-week open-label,non-randomized,single-center,pilot study,patients with T2DM receiving thrice-daily insulin or intensive insulin treatment were transitioned to twice-daily injections of insulin *** doses,hemoglobin A1c(HbA1c)levels,fasting blood glucose(FBG),hypoglycemic events,a Diabetes Treatment Satisfaction Questionnaire,and other parameters were assessed at baseline and *** This study included 21 participants.A marked enhancement was observed in the FBG level(P=0.02),daily total insulin dose(P=0.03),and overall diabetes treatment satisfaction(P<0.01)in the participants who switched to *** was a decrease in HbA1c levels(7.6±1.1 vs 7.4±0.9,P=0.31)and the frequency of hypoglycemic events of those who switched to IDegAsp decreased,however,there was no statistically significant *** The present findings suggest that treatment with IDegAsp enhances clinical outcomes,particularly FBG levels,daily cumulative insulin dose,and overall satisfaction with diabetes treatment.

关键词： Insulin degludec/aspart Type 2 diabetes management Basal-bolus insulin therapy Pre-mixed insulin Diabetes treatment satisfaction questionnaire

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