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Advances in the management of acute liver failure

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World Journal of Gastroenterology 2013年第41期19卷 7069-7077页

作者： Da-Wei Wang yi-mei yin Yong-Ming Yao Department of ICU Weihai Municipal Hospital Department of Ultrasound Weihai Municipal Hospital Department of Microbiology and Immunology Burns InstituteFirst HospitalAffiliated to the Chinese PLAGeneral Hospital

Acute liver failure(ALF)is an uncommon but dramatic clinical syndrome characterized by hepatic encephalopathy and a bleeding tendency due to abrupt loss of liver function caused by massive or submassive liver necrosis in a patient with a previously healthy *** causes of ALF encompass a wide variety of toxic,viral,metabolic,vascular and autoimmune insults to the liver,and identifying the correct cause can be difficult or even *** patients with ALF develop a cascade of serious complications involving almost every organ system,and death is mostly due to multi-organ failure,hemorrhage,infection,and intracranial ***,the outcome of ALF has been improved in the last 3 decades through the specific treatment for the disease of certain etiology,and the advanced intensive care *** most severely affected patients who fail to recover after treatment,rapid evaluation for transfer to a transplantation center and consideration for liver transplantation is mandatory so that transplantation can be applied before contraindications *** review focuses on the recent advances in the understanding of various contributing etiologies,the administration of etiology-specific treatment to alleviate the liver injury,and the management of complications(e.g.,encephalopathy,coagulopathy,cardiovascular instability,respiratory failure,renal failure,sepsis and metabolic disturbance)in patients with *** of the need for liver transplantation is also presented.

关键词： Acute liver failure Cerebral edema Liver transplantation

黄土丘陵区退耕还林还草对土壤细菌群落结构的影响

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环境科学 2018年第4期39卷 1824-1832页

作者：陈孟立曾全超黄懿梅倪银霞西北农林科技大学资源环境学院农业部西北植物营养与农业环境重点实验室杨凌712100

为了探究黄土丘陵区退耕还林还草工程对土壤细菌群落的影响,本文以宁南山区玉米农地为对照,人工柠条地和天然草地为退耕还林还草的处理,利用Illumina二代高通量测序技术Mi Seq对土壤细菌的16S rRNA V3~V4可变区进行测序,研究3种植被下... 详细信息

为了探究黄土丘陵区退耕还林还草工程对土壤细菌群落的影响,本文以宁南山区玉米农地为对照,人工柠条地和天然草地为退耕还林还草的处理,利用Illumina二代高通量测序技术Mi Seq对土壤细菌的16S rRNA V3~V4可变区进行测序,研究3种植被下土壤细菌的α多样性、物种组成和丰富度,并结合土壤理化性质探讨影响细菌群落结构的环境因素.3种土壤样品中共检测到细菌29门,76纲,135目,250科,375属,682种,主要的优势菌门为变形菌门(Proteobacteria)、放线菌门(Actinobacteria)、酸杆菌门(Acidobacteria)、绿弯菌门(Chloroflexi)、芽单胞菌门(Gemmatimonadetes)、厚壁菌门(Firmicutes),主要的优势菌纲为α-变形菌纲(α-Proteobacteria)、放线菌纲(Actinobacteria)、酸杆菌纲(Acidobacteria)、β-变形菌纲(β-Proteobacteria)、嗜热油菌纲(Thermoleophilia)、芽单胞菌纲(Gemmatimonadetes)、杆菌纲(Bacilli)、δ-变形菌纲(δ-Proteobacteria).与耕地相比,林地的优势菌主要是变形菌门(Proteobacteria)和放线菌门(Actinobacteria),草地的是放线菌门(Actinobacteria)和酸杆菌门(Acidobacteria).柠条林地的土壤微生物多样性最高.通过RDA分析发现,影响本研究区域土壤细菌分布的最主要环境因子是全氮和有机质.研究表明通过退耕还林与还草工程明显地改善了土壤肥力和环境状况,改变了土壤细菌群落组成.

关键词：黄土丘陵区退耕还林还草土壤细菌群落结构高通量测序技术

Exosomes:the next-generation therapeutic platform for ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1221-1235页

作者： Wenjing yin Hongyin Ma Yang Qu Jiaxin Ren yingying Sun Zhen-Ni Guo yi Yang Stroke Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuroscience Research Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

Current therapeutic strategies for ischemic stroke fall short of the desired objective of neurological functional ***,there is an urgent need to develop new methods for the treatment of this *** are natural cell-derived vesicles that mediate signal transduction between cells under physiological and pathological *** have low immunogenicity,good stability,high delivery efficiency,and the ability to cross the blood–brain *** physiological properties of exosomes have the potential to lead to new breakthroughs in the treatment of ischemic *** rapid development of nanotechnology has advanced the application of engineered exosomes,which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dosages *** in technology have also driven clinical translational research on *** this review,we describe the therapeutic effects of exosomes and their positive roles in current treatment strategies for ischemic stroke,including their antiinflammation,anti-apoptosis,autophagy-regulation,angiogenesis,neurogenesis,and glial scar formation reduction ***,it is worth noting that,despite their significant therapeutic potential,there remains a dearth of standardized characterization methods and efficient isolation techniques capable of producing highly purified *** optimization strategies should prioritize the exploration of suitable isolation techniques and the establishment of unified workflows to effectively harness exosomes for diagnostic or therapeutic applications in ischemic ***,our review aims to summarize our understanding of exosome-based treatment prospects in ischemic stroke and foster innovative ideas for the development of exosome-based therapies.

关键词： blood–brain barrier electroacupuncture engineering exercise exosomes ischemic stroke mesenchymal stem cells microglia neuroprotection stents

Finite element modeling of thermo-active diaphragm walls

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Frontiers of Structural and Civil Engineering 2020年第3期14卷 646-663页

作者： yi RUI mei yin Centre for Smart Infrastructure and Construction Department of EngineeringUniversity of CambridgeCambridgeCB3 OFAUK Civil and Environmental Engineering Department Brunei UnivisityLondon UBS 3PHUK

There are two major challenges faced by modern society:energy security,and lowering carbon dioxide gas ***-active diaphragm walls have a large potential to remedy one of these problems,since they are a renewable energy technology that uses underground infrastructure as a heat exchange ***,extensive research is required to determine the effects of cyclic heating and cooling on their geotechnical and structural *** this paper,a series of detailed finite element analyses are carried out to capture the fully coupled thermo-hydro-mechanical response bf the ground and diaphragm *** is demonstrated that the thermal operation of the diaphragm wall causes changes in soil temperature,thermal expansion/shrinkage of pore water,and total stress applied on the diaphragm ***,in turmn,cause displacements of the diaphragm wall and variations of the bending ***,these effects on the performance of diaphragm wall are not *** thermally induced bending strain is mainly governed by the temperature differential and uneven thermal expansion/shrinkage across the wall.

关键词： thermo-active diaphragm wall finite element analysis thermo-hyro-mechanical coupling ground source heat pump

Study on elasticity of rabbit liver during inferior vena cava clamping and reopening using acoustic radiation force impulse(ARFI)

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Study on elasticity of rabbit liver during inferior vena cav...

Low-Temperature Fabrication of Stable Black-Phase CsPbI₃ Perovskite Flexible Photodetectors Toward Wearable Health Monitoring

第二届长三角超声医学论坛暨2009年浙江省超声医学学术年会

作者： Department of Ultrasonography,The Second Affiliated Hospital of Wenzhou Medical College,Wenzhou 325027,China Pin-tong HUANG Fan-Lei KONG Lee WANG yi-mei yin Hui-liao HE Zhao-ling LU Chao ZHANG Xi-ming LV

Objective To evaluate the change of elasticity of rabbit liver after vena cava reopening using acoustic radiation force impulse(ARFI). Methods Seven health Japanese white big ear rabbits were used for this *** intravenous anesthesia via marginal vein,vena cava of rabbit was *** elasticity of right liver of rabbits was detected

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NANO-MICRO LETTERS 2025年第1期17卷 1-14页

作者： Zhao, yingjie Sun, yicheng Pei, Chaoxin yin, Xing Li, Xinyi Hao, yi Zhang, Mengru Yuan, Meng Zhou, Jinglin Chen, Yu Song, Yanlin Zhengzhou Univ Coll Chem Zhengzhou 450001 Peoples R China Zhengzhou Univ Pingyuan Lab Zhengzhou 450001 Peoples R China Chinese Acad Sci Inst Chem Key Lab Green Printing Beijing 100190 Peoples R China Chinese Acad Sci Tech Inst Phys & Chem Key Lab Bioinspired Mat & Interfacial Sci Beijing 100190 Peoples R China Chinese Acad Sci Inst High Energy Phys Beijing 100049 Peoples R China

Low-temperature fabrication of black-phase CsPbI3 perovskite films is first demonstrated by using diphenylphosphinic chloride additive under 30-50 degrees C, arising from the steric effect and chloride insertion ***-area high-quality all-inorganic perovskite films with fewer defects enhanced crystallographic orientation, and excellent environmental stability is *** record performances are demonstrated for flexible wearable photodetectors with a responsivity of 42.1 A W-1, a detectivity of 1.3 x 1014 Jones, high-fidelity image, photoplethysmography sensor functions, and high mechanical stability. Flexible wearable optoelectronic devices fabricated from organic-inorganic hybrid perovskites significantly accelerate the development of portable energy, biomedicine, and sensing fields, but their poor thermal stability hinders further applications. Conversely, all-inorganic perovskites possess excellent thermal stability, but black-phase all-inorganic perovskite film usually requires high-temperature annealing steps, which increases energy consumption and is not conducive to the fabrication of flexible wearable devices. In this work, an unprecedented low-temperature fabrication of stable black-phase CsPbI3 perovskite films is demonstrated by the in situ hydrolysis reaction of diphenylphosphinic chloride additive. The released diphenyl phosphate and chloride ions during the hydrolysis reaction significantly lower the phase transition temperature and effectively passivate the defects in the perovskite films, yielding high-performance photodetectors with a responsivity of 42.1 A W-1 and a detectivity of 1.3 x 1014 Jones. Furthermore, high-fidelity image and photoplethysmography sensors are demonstrated based on the fabricated flexible wearable photodetectors. This work provides a new perspective for the low-temperature fabrication of large-area all-inorganic perovskite flexible optoelectronic devices.

关键词： In situ hydrolyzation Low-temperature processing All-inorganic perovskite Flexible photodetectors Health monitoring

Experimental study and cellular automata simulation of corrosion behavior of ferritic stainless steel in molten aluminum

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Journal of Iron and Steel Research International 2022年第9期29卷 1485-1494页

作者： Ji-yin Long Tian-tian Zhao mei-yi Yuan yi-tao Yang School of Materials Science and Engineering Shanghai UniversityShanghai 200444China

The corrosion behavior of feritic stainless steel(446)after being immersed in molten Al alloy at 750℃ for 1,2,4,and 8 h has been investigated experimentally and *** microstructure and composition distribution at the corrosion interface were characterized using the optical microscope,scanning electron microscope,and energy dispersive *** results showed that Cr and Si synergistically delay the progress of corrosion at the interface of the intermetallic compounds(IMC).In the early stage of corrosion,Si element was enriched at the interface of IMC1 and IMC2,and the diffusion channels of Al element were occupied by ***,as the corrosion progresses,Cr and Si gradually gather to form a band-like structure and coarsen,causing their hindering effect to be *** the corrosion time increases,the banded structure was further aggregated and coarsened,and the inhibitory effect of Cr and Si elements on corrosion was strongly *** addition,based on the cellular automata dynamics model of reaction-diffusion,the corrosion process of ferritic stainless steel in aluminum alloy melts was *** is demonstrated that if there is no stabilizing effect of Cr element,the thickness of IMC will be doubled.

关键词： Stainless steel Molten Al alloy Intermetallic Diffusion-Cellular automata

Distributed fiber optic monitoring of a CFA pile with a central reinforcement bar bundle

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Frontiers of Structural and Civil Engineering 2021年第1期15卷 167-176页

作者： yi RUI Nicholas de BATTISTA Cedric KECHAVARZI Xiaomin XU mei yin Centre for Smart Infrastructure and Construction Department of EngineeringUniversity of CambridgeCambridge CB21TNUK Department of Engineering University of CambridgeCambridge CB21TNUK

In this paper,we present an application of distributed fiber optic sensor(DFOS)technology to measure the strain of a continuous flight auger(CFA)test pile with a central reinforcement bar bundle,during a static load test carried out in *** distributed in nature,DFOS gives much more information about the pile performance as compared to traditional point sensors,such as identifying cross-sectional irregularities or other *** strain profiles recorded along the depth of the piles from the DFOS were used to calculate pile deformation(contraction),shaft friction,and tip resistance under various *** on this pile load test,a finite element(FE)analysis was performed using a one-dimensional nonlinear load-transfer *** by the shaft friction and tip resistance derived from the monitored data,the FE model was able to simulate the pile and soil performance during the load testing with good *** effect of the reinforcement cage and central reinforcement bar bundle were investigated,and it was found that the addition of a reinforcement cage would reduce the pile settlement by up to 20%.

关键词： continuous flight auger pile static load test central reinforcement bar bundle distributed fiber optic sensor finite element load transfer

Simultaneous removal of sulfur dioxide and nitrogen oxide from flue gas by phosphorus sludge:The performance and absorption mechanism

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Chinese Journal of Chemical Engineering 2024年第1期65卷 212-221页

作者： Yuanyuan yin Xujun Wang Lei Xu Binbin He Yunxiang Nie yi mei Faculty of Chemical Engineering Kunming University of Science and TechnologyKunming 650500China Yunnan Provincial Key Laboratory of Energy Saving in Phosphorus Chemical Engineering and New Phosphorus Materials Kunming 650500China The Higher Educational Key Laboratory for Phosphorus Chemical Engineering of Yunnan Province Kunming 650500China

Developing low-cost and green simultaneous desulfurization and denitrification technologies is of great significance for sulfur dioxide(SO_(2))and nitrogen oxide(NO_(x))emission control at low temperatures,especially for small and medium-sized coal-fired boilers and ***,phosphorus sludge,an industrial waste from the production process of yellow phosphorus,has been developed to simultaneously eliminate SO_(2)and NO_(x)from coal-fired flue *** key factors affecting the experimental results indicate that desulfurization and denitrification efficiency of over 95%can be achieved at a low temperature of 55℃.Further,the absorption mechanism was investigated by characterizing the solid and liquid phases of the phosphorus sludge during the absorption *** efficient removal of SO_(2)is attributed to the abundance of iron(Fe^(3+))and manganese(Mn^(2+))in the ***_(2)can be rapidly catalyzed and converted to SO_(4)^(2-)by *** key to NOx removal is the oxidation of NO toward watersoluble high-valent nitrogen oxides by oxidizing reactive substances induced via yellow phosphorus,which are then absorbed by water and converted to NO_(3)^(-).Meanwhile,yellow phosphorus is oxidized to phosphoric acid(H_(3)PO_(4)).The spent absorption slurry can be reused through wet process phosphoric acid production,as it contains sulfuric acid(H_(2)SO_(4)),nitric acid(HNO_(3)),and H_(3)PO_(4).Accordingly,this is a technology with broad application prospects.

关键词： Absorption Oxidation Multiphase reaction Phosphorus sludge Yellow phosphorus Low temperature