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Correlation between blood circulation grading and angiogenesis using ultrasonic contrast of rabbit VX2 hepatic carcinoma

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Asian Pacific Journal of Tropical Medicine 2016年第2期9卷 148-153页

作者： Chang-Song Xu yi-jin su Ming Xu Wei Liu Peng Hao Lian-Fang Du Department of Ultrasound Huai'an First People's Hospital Nanjing Medical University Department of Ultrasound Shanghai General Hospital of Nanjing Medical University

Objective: To build the rabbit model of VX2 hepatic carcinoma, examine the tumor body using the ultrasonic contrast and study the correlation between the blood circulation grading and angiogenesis. Methods: The VX2 tumor strain was prepared in the lateral muscle of the hind legs of 40 male New Zealand rabbits (which were purchased from Nanjing Senbao Biotech Co., Ltd.). The tumor block was embedded in the center of left liver lobe directly to build the rabbit model of VX2 hepatic carcinoma. The ultrasonic contrast was performed 14 d after implanting the tumor body. The semi-quantitative classification (0-IV level) was taken according to the blood flow of tumor vessel. Animals were executed using the air embolism method. The liver was separated to extract RNA and total protein respectively. The real-time PCR and western blotting method were employed to detect the expression of angiogenesis-related factors of VEGF, bFGF and TNP-alpha, while the ultrasonic contrast to detect the correlation with blood circulation grading. The Pearson product moment correlation coefficient was used to measure the linear relationship between these two variables and analyze the correlation between the blood circulation grading and angiogenesis using the ultrasonic contrast. Results: Thirty-three rabbits had the successful model of VX2 hepatic carcinoma. The blood circulation grading by ultrasonic contrast was: 2 cases at level 0 (6.60%), 5 cases at level I (16.7%), 12 cases at level 11 (40.0%), 6 cases at level III (20.0%) (local dense or clustered blood flow) and 5 cases at level IV (16.7%). The results showed that there was positive correlation between three angiogenesis-related factors and the blood circulation grading. The correlation coefficient between three angiogenesis-related factors and the blood circulation grading was over 0.9, which indicated the relatively high correlation. Conclusions: The ultrasound blood circulation grading for the hepatic carcinoma can clearly reflect th

关键词： Hepatic carcinoma VX2 Ultrasonic contrast Angiogenesis bFGF TNF-alpha

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Research of green cement clinker calcinated from ferrochrome slag

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Journal of Environmental Sciences 1999年第4期11卷 403-406页

作者： LIU Xiao-bo FU Yong-jian XIAO Qiu-guo jin yi-su LIU Xiao-ping Department of Chemical Engineering Xiangtan Polytechnic Universi tyXiangtan 411201China

Ferrochrome slag is a kind of industrial waste containing Cr^(6+)and is produced in the process of silico ferrochrome *** the basis of analyzing the chemical composition and mineral composition of ferrochrome slag,this paper has put forward a technology of green portland cement clinker calcinated from ferrochrome *** the experiment,physical chemical changes of cement clinker in the burning process of ferrochrome slag were *** effects of calcinating temperature and clinker cooling rate on the solubility value of Cr^(6+)were *** results indicated that when the calcinating temperature is above 1450℃,and the cooling rate is beyond 120℃/min,Cr^(6+)in cement clinker is almost insoluble.

关键词： ferrochrome slag Cr^(6+) green cement clinker

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改进粒子群优化算法对反应动力学参数的估计

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中南大学学报（自然科学版） 2008年第4期39卷 694-699页

作者：金一粟周永华梁逸曾中南大学化学化工学院湖南长沙410083

针对粒子群算法容易早熟,全局寻优效率偏低等缺点,在原有算法的基础上对粒子群优化算法的速度权重和更新机制进行分析,提出更有效的可直接反映粒子空间分布的分布矢量以调整粒子搜索进程,并通过粒子对最优粒子的跨越机制增强粒子的全局... 详细信息

针对粒子群算法容易早熟,全局寻优效率偏低等缺点,在原有算法的基础上对粒子群优化算法的速度权重和更新机制进行分析,提出更有效的可直接反映粒子空间分布的分布矢量以调整粒子搜索进程,并通过粒子对最优粒子的跨越机制增强粒子的全局寻优能力。空间自适应粒子群优化算法(LAPSO)有机融合上述2种改进机制。通过对环辛二烯在球形粉状催化剂Pd/Al2O3上进行催化加氢反应的动力学分析,构建包含内、外效率因子的反应动力学模型。并根据所测实验数据,采用几种具有代表性的粒子群优化算法和LAPSO优化算法对相关动力学参数分别进行估计。参数估计的统计分析结果表明,LAPSO具有较强的全局寻优能力和较稳定的收敛特性,能够较好地用于解决化工中常见的非线性动力学参数估计问题。

关键词：空间自适应粒子群优化算法参数估计环辛二烯加氢

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High-temperature oxidation behavior and degradation mechanism of chromium-coated zirconium alloy cladding: a review

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Tungsten 2025年第1期7卷 50-70页

作者： yi Li Bei-Qi Wang Xin-yin Zhang Shi-Jie Wang Cong-yi Li Hui-Long Yang Ran-Ran su Tong Liu School of Mechanical Engineering Shanghai Jiao Tong University College and Graduate School of Arts and Sciences University of Virginia Global Institute of Future Technology Shanghai Jiao Tong University

Accident-tolerant fuels(ATF) have been extensively studied to reduce the production rate and total amount of heat and hydrogen generated from high-temperature steam oxidation during severe ***-coated zirconium alloy cladding has become one of the most promising candidates for ATF because of its excellent corrosion and oxidation *** paper provides a comprehensive overview of the research progress on oxidation behaviors and degradation mechanisms in chromium-coated zirconium alloy cladding under high-temperature *** techniques to strengthen the oxidation resistance are highlighted and ***,challenges and opportunities for various future directions are addressed.

关键词： Accident-tolerant fuel Chromium coating Degradation mechanism High-temperature oxidation behavior Zirconium alloy cladding

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Statistical characteristics and classification of ionospheric mid-latitude trough as revealed by the observations of DMSP-F18

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Earth and Planetary Physics 2025年第1期9卷 137-147页

作者： yi Liu JiuHou Lei FuQing Huang su Zhou School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China School of Science Guiyang UniversityGuiyang 550005China

Statistical characteristics and the classification of the topside ionospheric mid-latitude trough are systemically analyzed,using observations from the Defense Meteorological Satellite Program F18(DMSP-F18)*** data was obtained at an altitude of around 860 km in near polar orbit,throughout *** study identified the auroral boundary based on the in-situ electron density and electron spectrum,allowing us to precisely determine the location of the mid-latitude *** differs from most previous works,which only use Total Electron Content(TEC)or in-situ electron *** our study,the troughs exhibited a higher occurrence rate in local winter than in summer,and extended to lower latitudes with increasing geomagnetic *** was found that the ionospheric mid-latitude trough,which is associated with temperature changes or enhanced ion drift,exhibited distinct ***,the ionospheric mid-latitude troughs related to electron temperature(Te)peak were located more equatorward of auroral oval boundary in winter than in *** ionospheric mid-latitude troughs related to Te-maximum were less frequently observed at 60−70°S magnetic latitude and 90−240°E ***,the troughs related to ion temperature(Ti)maximums were observed at relatively higher latitudes,occurring more frequently in *** addition,the troughs related to ion velocity(Vi)maximums could be observed in all *** troughs with the maximum-Ti and maximum-Vi were located closer to the equatorward boundary of the auroral oval at the nightside,and in both *** implies that enhanced ion drift velocity contributes to increased collisional frictional heating and enhanced ion temperatures,resulting in a density depletion within the trough region.

关键词： topside ionosphere mid-latitude trough ionospheric main trough auroral oval boundary temperature maximum

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微乳液浸渍法制备粉状与整体式Pd催化剂及其催化加氢性能

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石油学报（石油加工） 2008年第6期24卷 635-639页

作者：周永华叶红齐金一粟中南大学化学化工学院粉体技术研究所湖南长沙410083

利用微乳液浸渍法制备了粉状及整体式Pd催化剂。采用TEM、SEM和XRD对粉状及整体式催化剂上的Pd微粒进行了表征。在浆态床与整体式反应器中,以1,5-环辛二烯(1,5-COD)催化加氢为模型反应,考察了粉状及整体式Pd催化剂的催化活性、选择性及... 详细信息

利用微乳液浸渍法制备了粉状及整体式Pd催化剂。采用TEM、SEM和XRD对粉状及整体式催化剂上的Pd微粒进行了表征。在浆态床与整体式反应器中,以1,5-环辛二烯(1,5-COD)催化加氢为模型反应,考察了粉状及整体式Pd催化剂的催化活性、选择性及稳定性。结果表明,Pd以10 nm左右的微粒负载于粉状载体表面,而以50～200 nm大小的微粒负载于多孔陶瓷载体的孔壁上。整体式Pd催化剂在消除内扩散、强化外部传质方面可达到浆态床粉状Pd催化剂的效果,而且前者稳定性远高于后者。

关键词：微乳液整体式催化剂钯 1,5-环辛二烯加氢

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Dissipation-free approach for realizing non-Hermitian dynamics in a superconducting circuit

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Science China(Physics,Mechanics & Astronomy) 2025年

作者： yi-Hao Kang Yang Xiao Yu Wang Qi-Ping su Chui-Ping Yang School of Physics Hangzhou Normal University Fujian Key Laboratory of Quantum Information and Quantum Optics Fuzhou University Department of Physics Fuzhou University

Non-Hermitian dynamics exhibits a wealth of surprising and potentially useful phenomena. However, it is typically realized by coupling a system with thermal reservoirs, which makes the system suffer from thermal fluctuations associated with the dissipation. Here, we propose a dissipation-free approach to realize non-Hermitian dynamics using a superconducting circuit composed of two resonators and a superconducting qutrit. The non-Hermiticity arises in the dynamical matrix for the evolution of the two resonators in the Heisenberg picture, via a photon-number non-conserved dynamics. The energy spectrum of the non-Hermitian dynamical matrix can be retrieved by measuring the state of the two resonators, and a phase transition of the energy spectrum can be observed by varying the control parameters. In the realization of the non-Hermitian dynamics, the dissipation of the system and the post-selection are not required. Thus, the approach is implemented in a deterministic way, and the reservoir-induced noise is suppressed. Numerical simulations indicate that the energy spectrum of the non-Hermitian dynamical matrix obtained via the measurement of the resonators is in accordance with the theoretical prediction. Moreover, we demonstrate the parity discrimination for the state of two four-level qudits as an application, exhibiting the potential of the non-Hermitian dynamics in the field of quantum measurement. This work opens a new avenue for the realization of non-Hermitian dynamics and may have a significant implication in exploring the non-Hermitian phenomena.

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Modeling and Capacity Configuration Optimization of CRH5 EMU On-Board Energy Storage System

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Energy Engineering 2025年第1期122卷 307-329页

作者： Mingxing Tian Weiyuan Zhang Zhaoxu su School of Automation and Electrical Engineering Lanzhou Jiaotong UniversityLanzhou730070China

In the context of the“dual carbon”goals,to address issues such as high energy consumption,high costs,and low power quality in the rapid development of electrified railways,this study focused on the China Railways High-Speed 5 Electric Multiple Unit and proposed a mathematical model and capacity optimization method for an onboard energy storage system using lithium batteries and supercapacitors as storage ***,considering the electrical characteristics,weight,and volume of the storage media,a mathematical model of the energy storage system was ***,to tackle problems related to energy consumption and power quality,an energy management strategy was proposed that comprehensively considers peak shaving and valley filling and power quality by controlling the charge/discharge thresholds of the storage *** optimization adopted a bilevel programming model,with the series/parallel number of storage modules as variables,considering constraints imposed by the Direct Current to Direct Current converter,train load,and *** improved Particle Swarm Optimization algorithm and linear programming solver were used to solve specific *** results show that the proposed onboard energy storage system can effectively achieve energy savings,reduce consumption,and improve power qualitywhile meeting the load and space limitations of the train.

关键词： Electrified railway regenerative braking bi-level programming on-board energy storage power quality capacity configuration

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新文科视域下综合性大学外语学科建设路径研究

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佳木斯大学社会科学学报 2022年第2期40卷 265-268页

作者：郭云金一粟中南大学外国语学院湖南长沙410083 中南大学教师教学发展中心湖南长沙410083

新文科背景下,作为我国高等教育主体力量的综合性大学,如何应对新一轮的机遇与挑战,顺应国家、社会需求,对接高等外语教育“新使命、大格局、新文科、大外语”的改革与发展理念,服务于卓越国际化人才培养?本文聚焦综合性大学外语学科的... 详细信息

新文科背景下,作为我国高等教育主体力量的综合性大学,如何应对新一轮的机遇与挑战,顺应国家、社会需求,对接高等外语教育“新使命、大格局、新文科、大外语”的改革与发展理念,服务于卓越国际化人才培养?本文聚焦综合性大学外语学科的建设与发展,结合中南大学外语学科建设的实例,探讨规划外语学科发展战略的充分依据和创新外语学科发展机制的可行路径。

关键词：新文科综合性大学外语学科学科建设

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Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid Eun Jeong Lee su Bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

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