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Synthesis and Crystal Structure of Bis[2-[2-(diethylamino)ethyliminomethyl]-4-nitrophenolato]dimethanolcobalt(II) Dinitrate

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Chinese Journal of Structural Chemistry 2006年第9期25卷 1090-1094页

作者： WEI yi-Jun WANG feng-wu ZHU Qi-Yong Department of Chemistry. Huainan Normal College Huainan 232001 China

The title mononuclear cobalt（Ⅱ） complex [Co（DENP）2（MeOH）2].2NO3 （DENP = 2-[2-（diethylamino）ethyliminomethyl]-4-nitrophenolate） was prepared and characterized by elemental analysis, 1R and single-crystal X-ray diffraction. The crystal belongs to the triclinic system, space group P1 with a = 8.297（1）, b = 11.075（2）, c = 11.134（2） ,A,α = 69.69（1）, β = 70.97（2）, γ = 84.02（2）°, Z = 1, V = 907.0（4） ,A^3, Dc= 1.424 g/cm^3, Mr = 777.66, λ（MoKα） = 0.71073 A,μ= 0.548 mm^-1, F（000） = 409, R = 0.0628 and wR = 0.1734. The complex consists of a [Co（DENP）2- （MeOH）2]^2＋ cation and two disordered nitrate anions. The Co atom, lying at the inversion centre, is six-coordinated by two DENP ligands and two MeOH molecules in an octahedral geometry. The molecules in the crystal are linked through intermolecular O-H...O, O-H...N and N-H...O hydrogen bonds, forming chains parallel to the b axis.

关键词： Schiff base cobalt crystal structure

Sarcomatoid intrahepatic cholangiocarcinoma with good patient prognosis after treatment with Huaier granules following hepatectomy:A case report

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World Journal of Clinical Cases 2022年第9期10卷 2829-2835页

作者： Ji-Ye feng Xian-Peng Li Zong-Yang wu Li-Ping ying Chang Xin Zhen-Zhen Dai Yao Shen yi-feng wu Department of Hepatobiliary&Pancreas Surgery The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Infectious Disease The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Pathology The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Radiology The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina

BACKGROUND Sarcomatoid intrahepatic cholangiocarcinoma(SICC)is an extremely rare and highly invasive malignant tumor of the *** precise pathologic mechanism of SICC has not been clearly identified,and the prognosis is very *** effectiveness of the treatment strategy of radical hepatectomy combined with Huaier granules has not yet been *** SUMMARY The patient was a 69-year-old male who presented with intermittent right upper abdominal pain for one month and 4-pound weight loss before *** magnetic resonance imaging and magnetic resonance cholangiopancreatography showed multiple stones in the bile ducts accompanied by dilatation of the intrahepatic and extrahepatic bile *** preoperative diagnoses were right intrahepatic bile duct stones and extrahepatic bile duct stones;thus,surgical resection was *** showed that the bile duct wall of the right anterior lobe was thickened,and a mass was visible in the ***,a biopsy was performed,and rapid frozen-section biopsy analysis indicated that the tumor was *** final diagnosis was SICC(T1a N0M0).Huaier granules were taken by the patient as anticancer therapy after *** patient attended follow-up for 72 mo with no tumor recurrence or *** Sarcomatous intrahepatic cholangiocarcinoma is an extremely rare,aggressive malignancy,and the diagnostic gold standard is pathological *** reported the first case of successful treatment with Huaier granules as anticancer therapy after surgery,which indicated that Huaier granules are safe and *** studies are needed to study the anticancer molecular mechanisms of Huaier granules in sarcomatous intrahepatic cholangiocarcinoma.

关键词： Sarcomatous intrahepatic cholangiocarcinoma Hepatectomy Huaier granules Diagnose Therapy Case report

Endostatin promotes the anabolic program of rabbit chondrocyte

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Cell Research 2005年第3期15卷 201-206页

作者： yi feng,yi Pin wu,Xu Dong ZHU,Yan Hong ZHANG,Qing Jun MA* Department of Molecule Genetics,Beijing Institute of Biotechnology,27 Taiping Road,Beijing 100850,China Department of Molecule Genetics Beijing Institute of Biotechnology Beijing China

Endostatin is a natural occurred angiogenesis inhibitor derived from collagenXVIII. So far its function during the angiogenesis process of bone formation and arthropathy has not been well studied yet. The present study addresses the function of endostatin in rabbit articular chondrocytes (RAC). We found that endostatin can promote RAC adhesion and spreading as well as its proliferation. In monolayer cultured RAC, CollagenII, TIMP1 and collagenXVIII transcription were up regulated by endostatin while collagenI and MMP9 were down regulated. Moreover collagenXVIII and endostatin antigens are present at synovial fluid. These findings indicate new function of endostatin as a homeostatic factor in cartilage metabolism.

关键词： endostatin angiogenesis chondrocyte matrix metalloproteinase.

COVID-19 or treatment associated immunosuppression may trigger hepatitis B virus reactivation: A case report

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World Journal of Clinical Cases 2021年第19期9卷 5266-5269页

作者： yi-feng wu Wan-Jun Yu Yu-Hua Jiang yin Chen Bo Zhang Rui-Bing Zhen Jun-Tao Zhang yi-Ping Wang Qiang Li feng Xu Yan-Jun Shi Xian-Peng Li Department of Hepatobiliary and Pancreas Surgery The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Respiratory Disease and Critical Care Medicine The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Infectious Diseases The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Ophthalmology The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Laboratory Medicine The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Radiology The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Gastroenterology The Affiliated People’s Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Hepatobiliary and Pancreas Surgery The Second Affiliated Hospital Zhejiang University School of MedicineHangzhou 315009Zhejiang ProvinceChina

BACKGROUND Since the initial recognition of coronavirus disease 2019(COVID-19)in wuhan,this infectious disease has spread to most areas of the *** pathogenesis of COVID-19 is yet *** B virus(HBV)reactivation occurring in COVID-19 patients has not yet been *** SUMMARY A 45-year-old hepatitis B man with long-term use of adefovir dipivoxil and entecavir for antiviral therapy had HBV reactivation after being treated with methylprednisolone for COVID-19 for 6 *** COVID-19 or treatment associated immunosuppression may trigger HBV reactivation.

关键词： COVID-19 Hepatitis B virus Reactivation Diagnose Therapy Case report

一种可滑移式铅芯橡胶支座的显式数值模拟与试验验证(英文)

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第5期18卷 363-376页

作者： yi-feng wu Hao WANG Ai-qun LI Dong-ming feng Ben SHA Yu-ping ZHANG School of Civil Engineering Southeast University Nanjing 210096 China Beijing Advanced Innovation Center for Future Urban Design Beijing University of Civil Engineering and Architecture Beijing 100044 China Department of Civil Engineering and Engineering Mechanics Columbia University New York NY 10027 USA

目的:随着隔震技术在工程结构中的逐步推广应用,橡胶隔震支座的试验与数值模拟都得到国内外工程研究人员的重视。其中后者因支座大变形时计算较难收敛、铅芯与周边橡胶以及钢板的复杂接触关系较难模拟、采用隐式积分算法时计算规模较难... 详细信息

目的:随着隔震技术在工程结构中的逐步推广应用,橡胶隔震支座的试验与数值模拟都得到国内外工程研究人员的重视。其中后者因支座大变形时计算较难收敛、铅芯与周边橡胶以及钢板的复杂接触关系较难模拟、采用隐式积分算法时计算规模较难控制等问题,目前仍是这一方向的研究热点。本文旨在探讨基于显式积分算法对一种新型可滑移式铅芯橡胶支座进行准确可行的数值模拟的方法。创新点:1.探究基于显式积分算法的隔震支座数值模拟方法;2.采取多种方法有效地控制了数值模拟计算规模,同时实现了较高的数值模拟精度;3.采用程序中提供的3种接触方式较好地模拟了支座中存在的复杂接触关系。方法:本文主要采用4种方法减小数值模拟计算规模:1.激活程序内置的质量缩放功能;2.合理增大支座中对支座竖向刚度与水平剪切性能影响较小的非关键部件——叠层钢板的厚度;3.合理减小叠层钢板的弹性模量;4.考虑到支座中所有材料均未考虑材料的率变效应,即加载速率对支座的力学性能没有影响,本文数值模拟中所用加载频率为实际加载频率的10倍。此外,本文采用了一般接触、绑定接触与单边接触模拟支座中不同的接触关系。结论:1.显式积分的计算时间步长由2.4×10-7 s增大到3.5×10-6 s;2.与试验结果对比验证了本文提出的基于显式积分算法对该新型可滑移式铅芯橡胶支座进行数值模拟的方法的准确实用性;3.该支座在纯压作用下,部分铅芯发生塑性变形,而在最大剪切位移时,铅芯发生了很大的塑性流动变形;4.与采用隐式算法对该支座进行数值模拟研究所用时间相比,显式算法所用时间少很多。

关键词：显式算法可滑移式铅芯支座计算时间步长接触关系试验验证

Hybrid coronary revascularization vs. percutaneous coronary interventions for multivessel coronary artery disease

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Journal of Geriatric Cardiology 2021年第3期18卷 159-167页

作者： Edward L.Hannan yi-feng wu Kimberly Cozzens Jacqueline Tamis-Holland Frederick S.K.Ling Alice K.Jacobs Ferdinand J.Venditti Peter B.Berger Gary Walford Spencer B.KingⅢ University at Albany State University of New YorkAlbanyNYUSA Mount Sinai St.Luke’s Hospital New YorkNYUSA University of Rochester Medical Center RochesterNYUSA Boston Medical Center BostonMAUSA Albany Medical Center AlbanyNYUSA Unaffiliated Johns Hopkins Medical Center Emory Health System AtlantaGAUSA

OBJECTIVE Hybrid coronary revascularization(HCR)combines a minimally invasive surgical approach to the left anterior descending(LAD)artery with percutaneous coronary intervention(PCI)for non-LAD diseased coronary *** is associated with shorter hospital lengths of stay and recovery times than conventional coronary artery bypass surgery,but there is little information comparing it to isolated PCI for multivessel *** objective is to compare long-term outcomes of HCR and PCI for patients with multivessel *** This cohort study used data from New York’s cardiac surgery and PCI registries in 2010−2016 to examine mortality and repeat revascularization rates for patients with multivessel coronary artery disease who underwent HCR and *** proportional hazards methods were used to reduce selection *** were followed for a median of four *** There was a total of 335 HCR patients(1.2%)and 25,557 PCI patients(98.8%)after *** was no difference in 6-year risk adjusted survival between HCR and PCI patients 83.17%vs.81.65%,adjusted hazard ratio(aHR)=0.90(95%CI:0.67−1.20).However,HCR patients were more likely to be free from repeat revascularization in the LAD artery(91.13%vs.83.59%,aHR=0.51(95%CI:0.34−0.77)).CONCLUSIONS For patients with multi-vessel coronary artery disease,HCR is rarely *** are no differences in mortality rates after four years,but HCR is associated with lower repeat revascularization rates in the LAD artery,presumably due to better longevity in left arterial mammary grafts.

关键词： coronary revascularization mortality

Numerical Study of Flow and Heat Transfer Characteristics of Shell-and-Tube Molten Salt Electric Heater with Circularly Perforated Baffles

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Journal of Thermal Science 2025年第1期34卷 24-33页

作者： LIN Yongjie ZHANG Cancan wu Yuting ZHANG yi LU Yuanwei Key Laboratory of Heat Transfer and Energy Conversion National User-Side Energy Storage Innovation Research and Development CenterBeijing University of Technology

Numerical simulations of the flow and heat transfer characteristics of four shell-and-tube molten salt electric heaters with different perforation rates was ***-and-tube electric heaters have the same geometry and tube arrangement,and all of them use single segmental baffles,but there exist four different baffle openings（φ）,i.e.,0%,2.52%,4.06%,and 6.31%.The results indicated that the reasonable baffle opening could significantly reduce the shell-side pressure drop,effectively decreasing the shell-side flow dead zone *** can eliminate the local high-temperature phenomenon on the surface of electric heating tubes,but the heat transfer coefficient is slightly *** perforated schemes significantly reduce shell-side pressure drop compared to the baseline solution without open *** particular,the φ=6.31% scheme exhibits the optimal performance among all the schemes,with a maximum reduction of up to 50.50% in shell-side pressure drop relative to the unopened holes *** heat transfer coefficient is the highest for φ=0%,exhibiting a range of5.26% to 5.73%,5.14% to 5.99%,and 7.31% to 8.54% higher than φ=2.52%,4.06%,and 6.31%,respectively,within the calculated *** composite index h/（Δp）1/3was higher for all open-hole solutions than that for the unopened-hole *** best overall performance was for φ=6.31%,which improved the composite index by15.29% to 17.18% over the unopened-hole solution.

关键词： molten salt electric heater perforated baffles heat transfer

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao Xiang feng Gao Yu-Gui Peng Peng wu Zong-Lin Li Xue-feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

Sky location of massive black hole binaries in the foreground of Galactic white dwarf binaries

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 97-108页

作者： Pan Guo Hong-Bo Jin Cong-feng Qiao Yue-Liang wu The International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of Sciences The School of Physical Sciences University of Chinese Academy of Sciences Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University National Astronomical Observatories Chinese Academy of Sciences Institute of Theoretical Physics Chinese Academy of Sciences

For space-based gravitational wave （GW） detection,the main noise source for massive black hole binaries （MBHBs） is attributed to approximately 10～7double white dwarf binaries in the *** a GW source,the amplitude of the detector response,recorded by a space-based gravitational wave detector,exhibits a modulation effect with a year period when observing the source from various orbital *** the adverse conditions mentioned above,where there is a strong foreground noise and annual modulation in the signals,we employed the wavelet transform and the strong-amplitude relevant orbital position search methods,which allows the weak MBHB sources to achieve higher locating *** detail,for two MBHB sources of lower intensity,the precision of luminosity distance,represented by the ratio ?DL/DLat the 95%confidence level,is enhanced by factors of ～*** angular resolutions,denoted by??s,are enhanced by a factor of ～*** improvements increase the number of detectable GW sources,facilitate multi-messenger follow-up observations and provide constraints on the cosmological constant.

关键词： space-based gravitational wave detection gravitational waves massive black hole binaries