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Radiation dose detection using a high-power portable optically stimulated luminescence real-time reading system

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Nuclear Science and Techniques 2018年第10期29卷 245-253页

作者： yi-Hang Wang Hua chen fei chen Yong-Gang Yuan Tai-Ping Peng Institute of Nuclear Physics and Chemistry Chinese Academy of Engineering Physics

Optically stimulated luminescence(OSL) reading systems are becoming smaller and capable of real-time detection. To improve real-time and multipurpose radiation dosimetry readings, we built a real-time continuous-wave(RCW) OSL reading system. This system is both small and lightweight, and it employs powerful laser excitation(478 mW/cm^2) at the dosimetry probe location. We investigate the possibility of using the RCW mode to read the radiation luminescence(RL) or OSL by using a singlecrystal Al_2O_3:C dosimeter in a low-dose-rate137 Cs y *** results indicate that the RL/OSL follows a stable and uniform distribution. The minimum detected doses associated with the RL, OSL, and RL + OSL signals are2.1 9 10^(-2), 3.17 9 10^(-1), and 5.7 9 10^(-2) l Gy, respectively. This device provides a framework for the future development of applications for practical radiation dose measurements.

关键词： OSL Real-time reading Al2O3:C Radiation dose

高原人群CYP2C9和VKORC1基因多态性及其与华法林用药剂量的相关性研究

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中国现代医学杂志 2022年第9期32卷 65-72页

作者：胡建鹏李云熊倩李宏伟陈坤前高连灏陈一非李秀萍王俊玲曲靖市第一人民医院检验中心云南曲靖655000 曲靖市第一人民医院麻醉科云南曲靖655000 曲靖市第一人民医院心脏血管外科云南曲靖655000 曲靖市第一人民医院神经介入科云南曲靖655000

目的探讨高原人群基于中国人群华法林用药剂量计算公式(PRC模型)和国际华法林遗传药理学协会推荐的亚裔人群华法林剂量计算公式(IWPC模型)两种模型预测剂量的准确性及其临床应用价值。方法回顾性分析曲靖市第一人民医院2016年10月—2020... 详细信息

目的探讨高原人群基于中国人群华法林用药剂量计算公式(PRC模型)和国际华法林遗传药理学协会推荐的亚裔人群华法林剂量计算公式(IWPC模型)两种模型预测剂量的准确性及其临床应用价值。方法回顾性分析曲靖市第一人民医院2016年10月—2020年1月375例行华法林代谢基因多态性检测患者的临床资料。通过qRT-PCR检测CYP2C9和VKORC1基因多态性,记录患者基本信息和临床用药情况,采用两种模型计算预测剂量并分析其与维持剂量[国际标准化比值(INR)稳定维持在2.0~3.0范围内时所服用的华法林剂量]的相关性,评估两模型预测的准确性。结果在实际治疗过程中患者是否选择服用华法林进行抗凝,通常与患者的性别、身高、吸烟史、是否合并房颤、是否注射低分子肝素钙无关,而与患者年龄、体重、体表面积(BSA)、初INR、是否置换主动脉瓣膜、是否服用阿司匹林、利伐沙班或氯吡格雷相关。375例患者CYP2C9和VKORC1基因频率符合Hardy-Weinberg遗传平衡定律,其中CYP2C9基因*1/*1(AA)、*1/*3(AC)及*3/*3(CC)基因型频率分别为93.07%(349/375)、6.93%(26/375)和0.00%(0/375),VKORC1-1639基因AA、AG和GG基因型频率分别为82.66%(310/375)、16.27%(61/375)和1.07%(4/375)。无论是使用PRC还是IWPC模型,除CYP2C9*1/*1&VKORC1AA(n=289)组与CYP2C9*1/*3&VKORC1AG(n=5)组预测剂量的差异无统计学意义(P>0.05)外,其他所有基因型组预测剂量两两比较均有差异(P0.05)。结论携带CYP2C9*3等位基因的患者对华法林更敏感,所需华法林剂量较低,而携带VKORC1-1639 G等位基因的患者需要更高剂量的华法林才可以获得有效的抗凝疗效。基因组学预测剂量可为临床使用华法林剂量提供依据,提高抗凝治疗的安全性和有效性。

关键词： CYP2C9基因 VKORC1基因基因多态性华法林剂量高原地区

Success of intravenous immunoglobulin and steroids in managing severe COVID-19 following lung transplantation:A case report

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World Journal of Transplantation 2025年第1期15卷 178-184页

作者： Yen-Shou Kuo Kuan-Hsun Lin ying-yi chen Yuan-Ming Tsai Ti-Hui Wu Hsu-Kai Huang Tsai-Wang Huang Division of Thoracic Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114202Taiwan

BACKGROUND Coronavirus disease 2019(COVID-19)pneumonia with severe septic shock and acute respiratory distress syndrome(ARDS)are critical illnesses for patients following *** immunoglobulin(IVIG)plays a role in both immune support and inflammation control,especially in immunocompromised *** case report describes the first successful experience using IVIG and pulse steroids to manage this critical condition following lung *** SUMMARY A 65-year-old male patient reported a history of chronic obstructive pulmonary disease and poor lung function and received bilateral sequential lung ***,he developed COVID-19 pneumonia,severe septic shock,and *** recovered from this critical condition after empirical antibiotics administration and veno-venous extracorporeal membrane oxygenation,in addition to IVIG and pulse *** IVIG is a valuable adjunct in managing severe sepsis in lung transplant recipients after COVID-19 *** aim,for the first time,to report the success of such a management approach for COVID-19 ARDS and sepsis in the post-lung transplant *** further investigations,this is a starting point for wider analysis of such an approach in this setting and consequently helps guide clinical practice for such a challenging patient population moving forward.

关键词： COVID-19 Septic shock Intravenous immunoglobulin Lung transplantation Post-transplant complications Case report

SYNERGISTIC EFFECTS OF NOVOLAC-BASED CHAR FORMER WITH A PHOSPHORUS/NITROGEN-CONTAINING FLAME RETARD ANT IN POLYAMIDE 6

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Chinese Journal of Polymer Science 2012年第1期30卷 72-81页

作者： Wei-cheng Xiong Li chen De-yi Wang fei Song Yu-zhong Wang Center for Degradation an-d Flame--Retardant Polymeric Materials College of-Chemistry State Key Laboratory of Polymer Materials Engineering National Engineering Laboratory of Eco-Friendly Polymeric Materials （Sichuan） Sichuan University Chengdu 610064 China

The synergistic effect of phosphorus oxynitride（PON） with a novolac-based char former modified by salification （NA-metal salt） on the flame retardance of polyamide 6（PA6） was *** this purpose,various flame-retardant PA6 systems were melt-compounded with PON,PON/NA,PON/NA-V_2O_5 and PON/NA-Fe_2O_3,and their flame retardance was evaluated by measuring the limiting oxygen index（LOI） values and UL-94 vertical burning *** results showed that,compared with the PA6/PON/NA system,the combination of two char formers（NA-V_2O_5,NA-Fe_2O_3） with PON could obviously improve the char formation and flame retardance of *** flame retardance and cone calorimetric analyses showed the stronger synergism as well as the better flame retardant performance of PON/NA-Fe_2O_3 flame retardant system. The effects of different char formers on the flame retardance and thermal stability of this system were also discussed.

关键词： Polyamide Flame retardance Novolac resin Synergistic effect

Revisiting Persistent Indexing Structures on Intel Optane DCPersistent Memory

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Journal of Computer Science & Technology 2021年第1期36卷 140-157页

作者： Heng Bu Ming-Kai Dong Ji-fei yi Bin-Yu Zang Hai-Bo chen Institute of Parallel and Distributed Systems Shanghai Jiao Tong UniversityShanghai 200240China

Persistent indexing structures are proposed in response to emerging non-volatile memory(NVM)to provide high performance yet durable ***,due to the lack of real NVM hardware,many prior persistent indexing structures were evaluated via emulation,which varies a lot across different setups and differs from the real ***,Intel has released its Optane DC Persistent Memory Module(PMM),which is the first production-ready *** this paper,we revisit popular persistent indexing structures on PMM and conduct comprehensive evaluations to study the performance differences among persistent indexing structures,including persistent hash tables and persistent *** to the evaluation results,we find that Cacheline-Conscious Extendible Hashing(CCEH)achieves the best performance among all evaluated persistent hash tables,and Failure-Atomic ShifT B+-Tree(FAST)and Write Optimal Radix Tree(WORT)perform better than other ***,we find that the insertion performance of hash tables is heavily influenced by data locality,while the insertion latency of trees is dominated by the flush *** also uncover that no existing emulation methods accurately simulate PMM for all the studied data ***,we provide three suggestions on how to fully utilize PMM for better performance,including using clflushopt/clwb with sfence instead of clflush,flushing continuous data in a batch,and avoiding data access immediately after it is flushed to PMM.

关键词： persistent memory data structure performance Intel Optane DC persistent memory module(PMM)

SETI strategy with FAST fractality

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Research in Astronomy and Astrophysics 2021年第7期21卷 234-240页

作者： yi-Xuan chen Wen-fei Liu Zhi-Song Zhang Tong-Jie Zhang Department of Astronomy Beijing Normal UniversityBeijing 100875China College of Physics and Electronic Engineering Qilu Normal UniversityJinan 250200China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China

We applied the Koch snowflake fractal antenna in planning calibration of the Five-hundred-meter Aperture Spherical radio Telescope(FAST), hypothesizing second-order fractal primary reflectors can optimize the orientated sensitivity of the telescope. Meanwhile, on the grounds of NASA Science Working Group Report in 1984, we reexamine the strategy of Search for Extraterrestrial Intelligence(SETI).A mathematical analysis of the radar equation will be performed in the first section, aiming to make it convenient to design a receiver system that can detect activities of an extraterrestrial civilization, according to the observable region of the narrowband. Taking advantage of the inherent potential of FAST, we simulate the theoretical detection of a Kardashev Type I civilization by a snowflake-selected reflecting area(Drake et al.).

关键词： SETI FAST fractal antennae

Tuning the interfacial reaction environment via pH-dependent and induced ions to understand C–N bonds coupling performance in NO3- integrated CO2 reduction to carbon and nitrogen compounds over dual Cu-based N-doped carbon catalyst

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Journal of Energy Chemistry 2025年第1期 273-285页

作者： Tianhang Zhou chen Shen Zhenghao Wu Xingying Lan yi Xiao College of Carbon Neutrality Future Technology State Key Laboratory of Heavy Oil Processing China University of Petroleum (Beijing) Institute of Materials Science TU Darmstadt Department of Chemistry Xi'an Jiaotong-Liverpool University Department of Mechanical and Mechatronics Engineering and Waterloo Institute of Nanotechnology University of Waterloo Waterloo

Dual atomic catalysts （DAC）,particularly copper （Cu2）-based nitrogen （N） doped graphene,show great potential to effectively convert CO2and nitrate （NO3-） into important industrial chemicals such as ethylene,glycol,acetamide,and urea through an efficient catalytical process that involves C–C and C–N ***,the origin of the coupling activity remained unclear,which substantially hinders the rational design of Cu-based catalysts for the N-integrated CO2reduction reaction （CO2RR）.To address this challenge,this work performed advanced density functional theory calculations incorporating explicit solvation based on a Cu2-based N-doped carbon (Cu2N6C10) catalyst for *** calculations are aimed to gain insight into the reaction mechanisms for the synthesis of ethylene,acetamide,and urea via coupling in the interfacial reaction *** to the sluggishness of CO2,the formation of a solvation electric layer by anions （F-,Cl-,Br-,and I-） and cations (Na+,Mg2+,K+,and Ca2+) leads to electron transfer towards the Cu *** process significantly accelerates the reduction of *** results reveal that*CO intermediates play a pivotal role in N-integrated ***,the Cu2-based N-doped carbon catalyst examined in this study has demonstrated the most potential for C–N coupling to *** findings reveal that through the process of a condensation reaction between*CO and NH2OH for urea synthesis,*NO3-is reduced to*NH3,and*CO2to*CCO at dual Cu atom *** dual-site reduction facilitates the synthesis of acetamide through a nucleophilic reaction between NH3and the ketene ***,we found that the I-and Mg2+ions,influenced by pH,were highly effective for acetamide and ammonia synthesis,except when F-and Ca2+were ***,the mechanisms of C–N bond formation were investigated via ab-initio molecular dynamics simulations,and we found that adjusting the micro-environment can change the dominant side reaction,shift

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Altered Expression of COMP,Collagen 1,and MMP9 in Pelvic Organ Prolapse

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Biomedical and Environmental Sciences 2023年第10期36卷 979-982页

作者： chen yi fei XU Hai Nan DUAN yi Nan XIA Zhi Jun Department of Obstetrics and Gynecology Shengjing Hospital of China Medical UniversityShenyang 110004LiaoningChina Department of Obstetrics and Gynecology Liaoning Province Hospital for Women and ChildrenShenyang 110004LiaoningChina Department of Gynecology Obstetrics and Gynecology Hospital of Fudan UniversityShanghai 200090China

Female pelvic organ prolapse(POP)is a common disorder that affects the quality of life of women *** in China have reported a 9.6%prevalence of symptomatic POP in adult women[1],with a higher prevalence among older women.

关键词： Collagen MMP9 COMP POP

Multi-Agent Control:A Graph-Theoretic Perspective

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Journal of Systems Science & Complexity 2021年第5期34卷 1973-2002页

作者： chen fei REN Wei State Key Laboratory of Synthetical Automation for Process Industries Northeastern UniversityShenyang 110004China School of Control Engineering Northeastern University at QinhuangdaoQinhuangdao 066004China. Department of Electrical and Computer Engineering University of CaliforniaRiversideCA 92521USA

Progress in development of multi-agent control is *** approaches for multiagent control,estimation,and optimization are discussed in a systematic way with particular emphasis on the graph-theoretic *** is paid to the design of multi-agent systems via Laplacian dynamics,as well as the role of the graph Laplacian spectrum,the challenges of unbalanced digraphs,and consensus-based estimation of graph *** emergent issues,e.g.,distributed optimization,distributed average tracking,and distributed network games,are also reported,which have witnessed extensive development *** are over 200 references listed,mostly to recent contributions.

关键词： Consensus cooperative control distributed average tracking distributed optimization multi-agent system