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Assessment of climate damage in China based on integrated assessment framework

Advances in Climate change Research 2024年第1期15卷 124-133页

作者： Jie liu Xiang-Zhen SHI Li YANG chang-yi liu Jin-Cheng WANG Rui-Min ZHU Xue-Li SHI Qiu-Feng liu International Business School Shanxi Normal UniversityXi'an 710062China University of Chinese Academy of Social Sciences Bejing 102488China School of Economics and Management Xinjiang UniversityUrumqi 830046China Global Energy Interconnection Development and Cooperation Organization(GEIDCO) Bejing 100031China Hubei Enshi College Enshi 445099China CMA Earth System Modeling and Prediction Centre China Meteorological AdministrationBeijing 100081China National Climate Centre China Meteorological AdministrationBeijing 100081China

Developing a localized and consistent model framework for climate loss and damage assessment is crucial for the policy-making of climate change mitigation and *** study introduces a comprehensive,multidisciplinary Integrated Assessment Model(IAM)framework for evaluating climate damage in China,utilizing BCC-SESM climate model and FUND sectoral climate damage model under the SSP2-RCPs *** a bottom-up approach,the research estimates climate damage across eight major sectors,recalibrates sectoral climate damage functions and parameters for China,and elucidates distinctions among direct climate loss,market climate loss,and aggregate climate *** findings reveal that the total climate damage function for China follows a quadratic pattern in response to temperature *** 2050,the estimated climate damage is projected to be 5.4%,5.7%,and 8.2%of GDP under RCP2.6,RCP4.5,and RCP8.5,***,both direct and market climate losses are projected to remain below 2%of GDP by 2050,while the aggregate climate loss could reach as high as 8.2%,which is predominantly attributed to non-market *** a sectoral perspective,under the RCP8.5 scenario,human health damage constitutes the largest share(61.9%)of the total climate loss by 2050,followed by sea-level rise damage(18.6%).This study sheds lights on the adaptation policy that should attach importance to the non-market sectors,particularly focusing on human health and sea-level rise.

关键词： Climate loss and damage Integrated assessment model(IAM) FUND model Representative concentration pathways(RCPs)scenario BCC-SESM

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Revisiting BCC-SESM parameters sensitivity with BCC-CSM1.1 co_(2)-concentration-driven simulations

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Advances in Climate change Research 2022年第3期13卷 301-308页

作者： chang-yi liu ying Lu Xue-Li Shi Guo-Quan Hu Qiu-Feng liu Chao Wei Yun-Fei Cao National Climate Centre China Meteorological Administration(CMA)Beijing 100081China Global Energy Interconnection Group Corporation(GEIDCO) Beijing 100031China North China Electric Power University(Baoding) Baoding 071003China CMA Earth System Modeling and Prediction Centre Beijing 100081China Center for Energy&Environmental Policy Research Beijing Institute of TechnologyBeijing 100081China

Based on the results of the complex climate model BCC-CSM,the Beijing Climate Center Simple Earth System Model(BCC-SESM)was developed for climate system simulations in Integrated Assessment Models(IAMs).The first version of the BCC-SESM model was based on a high-emissions scenario(ESMRCP8.5)and tends to overestimate the temperatures in low and medium emissions *** address this problem,this study uses three CO_(2)-concentration-driven simulations under different RCP scenarios of complex climate models to evaluate parameters sensitivity and their impacts on projection *** results show that the new version of the BCC-SESM(denoted as BCC-SESM1.1)model based on a medium-emissions scenario experiment(RCP4.5)is more suitable for temperature projections for various climate *** can well reproduce the original value of complex climate *** the same time,it also has high predictive efficacies for medium(RCP4.5)and low(RCP2.6)emissions scenarios,although it tends to underestimate for high emissions scenario(RCP8.5).The sensitivity tests for different RCP scenarios shows that the BCC-SESM1.1 has higher efficacy in projections of future climate change than those model versions based on the other *** projection deviations for the global average temperature by the BCC-SESM1.1(<2%)are better than the previous BCC-SESM(<5%).In light of recent progress in climate policy,the BCC-SESM1.1 is hence more suitable for coupling with IAMs for the purposes of assessing climate outcomes.

关键词： Simple climate model Integrated assessment models BCC-CSM1.1 CMIP5 BCC-SESM

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Impact of the cold surge event in January 2021 on the power system of China

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Advances in Climate change Research 2022年第6期13卷 803-810页

作者： chang-yi liu Bo LU Lu JIN Hao CHEN Jie WU Yang XIANG Zhi-Yuan MA Zi-Jian ZHAO Fang YANG Qing liu Jiang-Tao LI Global Energy Interconnection Development and Cooperation Organization(GEIDCO) Beijing 100031China National Climate Centre China Meteorological AdministrationBeijing 100081China Renmin University of Chin1 Beijing 100872China State Grid Energy Research Institute Co. Ltd.Beijing 102211China

During 6-10 January 2021,a recorded strong cold surge took place in China,with over 800 observational stations reaching their historical *** previous studies that focused on the response of either the power load or generation separately,this study quantitatively revealed the impacts on the balance between the demand and supply sides of the *** the demand side,the sensitivity of power load was found to increase substantially higher in southern China(0.533 GW°C^(−1))than in the northern region(0.139 GW°C^(−1))due to the limited municipal heating *** the supply side,the hourly wind power generation dropped from the highest of 110 GW on 6 January to the lowest of 54 GW on 9 January due to the reduction in wind *** addition,a reduction in solar power generation was observed during 8-10 ***,the balance of the power system was influenced by this cold *** an effective adaptation measure,results further showed that early warning by three weeks ahead can be obtained by an operational climate *** sensitivity of China's power system to such cold surge events may increase remarkably due to the expected increase in the proportion of wind and solar power generation in future new-type power ***,close cooperation between climate scientists and power engineers is needed to build the resilience of the power system to the cold extremes.

关键词： Cold surge event Power load Renewable power generation Sub-seasonal prediction Adaptation

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Recent landscape and trends for industry-sponsored pediatric clinical trials in China from 2013 to 2022

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Pediatric Investigation 2024年第1期8卷 12-20页

作者： chang liu yi liu Ling Ou Yuenan Qi Jianmin Zhang Drug Clinical Trial Institution Children’s HospitalCapital Institute of PediatricsBeijingChina

Importance:Pediatric medication is a challenging issue *** trials of medications for children and implementing measures to encourage innovation for addressing unmet medical and health needs are ***:To explore the recent landscape of pediatric clinical trials of new investigational drugs conducted by pharmaceutical enterprises in China from 2013 to 2022 to provide insight into pediatric drug development in the pharmaceutical industry and regulatory policy ***:We performed a cross-sectional observational investigation of pediatric clinical trials registered from January 1,2013,to December 31,2022,on the Registration and Information Disclosure Platform for Drug Clinical Trials,the official registration platform established in 2013 for trials of new investigational drugs initiated by biopharmaceutical *** that included pediatric participants(under 18 years old)were retrieved,and their relevant characteristics were extracted and ***:In total,895 pediatric clinical trials were collected,accounting for 5.1%of the total registered clinical trials initiated prior to January 1,*** overall average annual growth rate for the number of pediatric clinical trials was 12%(P<0.001).Phase III trials accounted for the highest proportion(49.1%,439).Of the 895 trials included,736(82.2%)were domestic trials,and 159(17.8%)were international multicenter *** terms of tested drugs,investigations of biological products accounted for the largest proportion of trials(67.4%,603).Among pediatric clinical trials,studies of vaccines accounted for the largest proportion of trials(41.0%,367),followed by trials for rare diseases(17.2%,154).Furthermore,geographical distribution analysis revealed that the largest and smallest numbers of trials were conducted in North China(35.7%,320)and Northeast China(0.8%,7),***:The growth trends for industry-sponsored clinical trials involving children illust

关键词： Geographic distribution Pediatric clinical trials Pediatric medication Rare disease

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Assessment of the triglyceride glucose index in adult patients with chronic diarrhea and constipation

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World Journal of Clinical Cases 2024年第6期12卷 1094-1103页

作者： Jing-yi Zhu Mu-Yun liu chang Sun Department of Gastroenterology The First Affiliated Hospital of Naval Medical UniversityShanghai 200433China Department of Gastroenterology Navy No.905 HospitalNaval Medical UniversityShanghai 200433China

BACKGROUND Accumulating evidence suggests that the gut microbiome is involved in the pathogenesis of insulin resistance(IR).However,the link between two of the most prevalent bowel disorders,chronic diarrhea and constipation,and the triglyceride glucose(TyG)index,a marker of IR,has not yet been *** To investigate the potential association between TyG and the incidence of chronic diarrhea and *** This cross-sectional study enrolled 2400 participants from the National Health and Nutrition Examination Survey database from *** was used as an exposure variable,with chronic diarrhea and constipation as determined by the Bristol Stool Form Scale used as the outcome variables.A demographic investigation based on TyG quartile subgroups was *** application of multivariate logistic regression models and weighted generalized additive models revealed potential correlations between TyG,chronic diarrhea,and *** analyses were performed to examine the stability of any potential *** In the chosen sample,chronic diarrhea had a prevalence of 8.00%,while chronic constipation had a prevalence of 8.04%.In multiple logistic regression,a more prominent positive association was found between TyG and chronic diarrhea,particularly in model 1(OR=1.45;95%CI:1.17-1.79,P=0.0007)and model 2(OR=1.40;95%CI:1.12-1.76,P=0.0033).No definite association was observed between the TyG levels and chronic *** weighted generalized additive model findings suggested a more substantial positive association with chronic diarrhea when TyG was less than 9.63(OR=1.89;95%CI:1.05-3.41,P=0.0344),and another positive association with chronic constipation when it was greater than 8.2(OR=1.74;95%CI:1.02-2.95,P=0.0415).The results of the subgroup analyses further strengthen the extrapolation of these results to a wide range of *** Higher TyG levels were positively associated with abnormal bowel health.

关键词： Triglyceride glucose index National Health and Nutrition Examination Survey Chronic diarrhea Chronic constipation Cross-sectional study Bowel health

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Non-B-form DNA is associated with centromere stability in newly-formed polyploid wheat

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Science China(Life Sciences) 2024年第7期67卷 1479-1488页

作者： Congyang yi Qian liu Yuhong Huang chang liu Xianrui Guo Chaolan Fan Kaibiao Zhang Yang liu Fangpu Han Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Non-B-form DNA differs from the classic B-DNA double helix structure and plays a crucial regulatory role in replication and ***,the role of non-B-form DNA in centromeres,especially in polyploid wheat,remains ***,we systematically analyzed seven non-B-form DNA motif profiles(A-phased DNA repeat,direct repeat,G-quadruplex,inverted repeat,mirror repeat,short tandem repeat,and Z-DNA)in hexaploid *** found that three of these non-B-form DNA motifs were enriched at centromeric regions,especially at the CENH3-binding sites,suggesting that non-B-form DNA may create a favorable loading environment for the CENH3 *** investigate the dynamics of centromeric non-B form DNA during the alloploidization process,we analyzed DNA secondary structure using CENH3 ChIP-seq data from newly formed allotetraploid wheat and its two diploid *** found that newly formed allotetraploid wheat formed more non-B-form DNA in centromeric regions compared with their parents,suggesting that non-B-form DNA is related to the localization of the centromeric regions in newly formed ***,non-B-form DNA enriched in the centromeric regions was found to preferentially form on young LTR retrotransposons,explaining CENH3's tendency to bind to younger ***,our study describes the landscape of non-B-form DNA in the wheat genome,and sheds light on its potential role in the evolution of polyploid centromeres.

关键词： non-B-form DNA polyploid wheat centromere retrotransposon

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Self-Driven Photo-Polarized Water Molecule-Triggered Graphene-Based Photodetector

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Research 2024年第2期2023卷 273-283页

作者： Shisheng Lin chang liu Xin Chen yi Zhang Hongtao Lin Xutao Yu Yujiao Bo Yanghua Lu College of Information Science and Electronic Engineering Zhejiang UniversityHangzhou 310027P.R.China Hangzhou Gelanfeng Technology Co.Ltd Hangzhou 310051P.R.China State Key Laboratory of Modern Optical Instrumentation Zhejang UniversityHangzhou 310027P.R.China Key Laboratory of Wide Bandgap Semiconductor Materials and Devices HCSemitek CorporationYiwu 322009P.R.China Smart Materials for Architecture Research Lab Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100P.R.China

Flowing water can be used as an energy source for generators,providing a major part of the energy for daily ***,water is rarely used for information or electronic ***,we present the feasibility of a polarized liquid-triggered photodetector in which polarized water is sandwiched between graphene and a *** to the polarization and depolarization processes of water molecules driven by photogenerated carriers,a photo-sensitive current can be repeatedly produced,resulting in a high-performance *** response wavelength of the photodetector can be fine-tuned as a result of the free choice of semiconductors as there is no requirement of lattice match between graphene and the *** zero voltage bias,the responsivity and specific detectivity of Gr/NaCl(0.5 M)W/N-GaN reach values of 130.7 mA/W and 2.3×10^(9)Jones under 350 nm illumination,***,using a polar liquid photodetector can successfully read the photoplethysmography signals to produce accurate oxygen blood saturation and heart *** with the commercial pulse oximetry sensor,the average errors of oxygen saturation and heart rate in the designed photoplethysmography sensor are~1.9%and~2.1%,*** study reveals that water can be used as a high-performance photodetector in informative industries.

关键词： polarization polarized saturation

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A stable staggered-grid finite-difference scheme for acoustic modeling beyond conventional stability limit

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Petroleum Science 2024年第1期21卷 182-194页

作者： Jing-yi Xu Yang liu National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing 102249China China University of Petroleum(Beijing) Karamay CampusKaramay 834000XinjiangChina

Staggered-grid finite-difference(SGFD)schemes have been widely used in acoustic wave modeling for geophysical *** improved methods are proposed to enhance the accuracy of numerical ***,these methods are inevitably limited by the maximum Courant-Friedrichs-Lewy(CFL)numbers,making them unstable when modeling with large time sampling intervals or small grid *** solve this problem,we extend a stable SGFD scheme by controlling SGFD dispersion relations and maximizing the maximum CFL ***,to improve modeling stability,we minimize the error between the FD dispersion relation and the exact relation in the given wave-number region,and make the FD dispersion approach a given function outside the given wave-number area,thus breaking the conventional limits of the maximum CFL ***,to obtain high modeling accuracy,we use the SGFD scheme based on the Remez algorithm to compute the FD *** addition,the hybrid absorbing boundary condition is adopted to suppress boundary reflections and we find a suitable weighting coefficient for the proposed *** derivation and numerical modeling demonstrate that the proposed scheme can maintain high accuracy in the modeling process and the value of the maximum CFL number of the proposed scheme can exceed that of the conventional SGFD scheme when adopting a small maximum effective wavenumber,indicating that the proposed scheme improves stability during the modeling.

关键词： Acoustic wave Staggered-grid finite-difference(SGFD) modeling Courant-friedrichs-lewy(CFL)number Stability

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Yeast-Controlled Double-Shelled CacO_(3)/CaF_(2)Hollow Nanospheres with Hierarchically Porous for Sustained pH-Sensitive Drug Release

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Chinese Journal of Chemistry 2024年第15期42卷 1713-1720页

作者： Xinhe liu yi chang Guanglei Ma Tingting liu Penghui Song Heng Yu Xueqing Ren Yuming Guo Xiaoming Ma School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiangHenan 453007China Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and ReactionsMinistryof EducationHenan Normal UniversityXinxiangHenan 453007China

Hierarchically porous materials(HP materials)are believed one of the most hopeful matrix materials because of their distinctive multimodal pore structures and tremendous application potentials in the field of ***,green and facile synthesis of hierarchically porous nanomaterials with beneficial water dispersibility and biocompatibility is still a great ***,a novel biomimetic strategy is proposed to prepare the cell-tailored double-shelled HPCaCO_(3)/CaF_(2) hollow nanospheres under the mediation of yeast *** biomolecules derived from the secretion of yeast cells are used as conditioning and stabilizing agents to control the biosynthesis of the HPCaCO_(3)/CaF_(2) materials,which exhibit excellent water dispersibility and favorable *** double-shelled CaCO_(3)/CaF_(2) nanospheres hold hierarchically porous structure and have abundant pore channel and large specific surface area,showing high drug-loading and a prolonged drug sustainable release profile by the pore-by-pore diffusion pattern of the hierarchical ***,the HPCaCO_(3) with pH-sensitivity could controllably release drug doxorubicin hydrochloride(DOX)at the acidic tumor *** in vitro and in vivo results demonstrate that HPCaCO_(3)/CaF_(2) has the sustainable pH-sensitive drug release property,showing an enhanced therapeutic ***,this study provides a biomimetic strategy to synthesize the hierarchically porous double-shelled hollow nanomaterials for applying in sustainable drug delivery system.

关键词： Biomimetic synthesis Hierarchically porous Sustained pH-sensitive drug release Antitumor agents Drug delivery Calcium Cancer therapy/Hollow structures

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Tuning interface mechanism of FeCo alloy embedded N,S-codoped carbon substrate for rechargeable Zn-air battery

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Journal of Energy Chemistry 2024年第6期93卷 400-410,I0010页

作者： Hui chang Lulu Zhao Shan Zhao Zong-Lin liu Peng-Fei Wang ying Xie Ting-Feng yi School of Materials Science and Engineering Northeastern UniversityShenyang 110819LiaoningChina Key Laboratory of Functional Inorganic Material Chemistry Ministry of EducationSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin 150080HeilongjiangChina Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province School of Resources and MaterialsNortheastern University at QinhuangdaoQinhuangdao 066004HebeiChina

The interface mechanism between catalyst and carbon substrate has been the focus of *** this paper,the FeCo alloy embedded N,S co-doped carbon substrate bifunctional catalyst(FeCo/S-NC)is obtained by a simple one-step pyrolysis *** experimental results and density functional theory(DFT)calculation show that the formation of FeCo alloy is conducive to promoting electron transfer,and the introduction of S atom can enhance the interaction between FeCo alloy and carbon substrate,thus inhibiting the migration and agglomeration of particles on the surface of carbon *** FeCo/SNC catalysts show outstanding performance for oxygen reduction reaction(ORR)and oxygen evolution reaction(OER).FeCo/S-NC shows a high half-wave potential(E_(1/2)=0.8823 V)for ORR and a low overpotential at 10 mA cm^(-2)(E_(j=10)=299 mV)for *** addition,compared with Pt/C+RuO_(2) assembled Zn-air battery(ZAB),the FeCo/S-NC assembled ZAB exhibits a larger power density(198.8 mW cm^(-2)),a higher specific capacity(786.1 mA h g_(zn)~(-1)),and ultra-stable cycle *** results confirm that the optimized composition and the interfacial interaction between catalyst and carbon substrate synergistically enhance the electrochemical performance.

关键词： FeCo alloy N S co-doped carbon DFT calculation Zn-air batteries Interfacial interaction

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