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Emerging trends and hotspots of Nuclear factor erythroid 2-related factor 2 in nervous system diseases

World Journal of Clinical Cases 2023年第32期11卷 7833-7851页

作者： Xue-Qin Chang Ling Xu yi-xuan Zuo yi-Guo Liu Jia Li Hai-Tao Chi Department of Neurology Xinhua Hospital Affiliated with Dalian UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND The Nuclear factor erythroid 2-related factor 2(NRF2)transcription factor has attracted much attention in the context of neurological ***,none of the studies have systematically clarified this field's research hotspots and evolution *** To investigate the research hotspots,evolution patterns,and future research trends in this field in recent *** We conducted a comprehensive literature search in the Web of Science Core Collection database using the following methods:(((((TS=(NFE2 L2))OR TS=(Nfe2 L2 protein,mouse))OR TS=(NF-E2-Related Factor 2))OR TS=(NRF2))OR TS=(NFE2L2))OR TS=(Nuclear factor erythroid2-related factor 2)AND(((((((TS=(neurological diseases))OR TS=(neurological disorder))OR TS=(brain disorder))OR TS=(brain injury))OR TS=(central nervous system disease))OR TS=(CNS disease))OR TS=(central nervous system disorder))OR TS=(CNS disorder)AND Language=English from 2010 to *** are just two forms of literature available:Articles and *** were processed with the software Cite-Space(version 6.1.R6).RESULTS We analyzed 1884 articles from 200 schools in 72 countries/*** 2015,the number of publications in this field has increased *** has the largest number of publications,but the articles published in the United States have better centrality and *** the top ten authors with the most published papers,five of them are from China,and the author with the most published papers is Wang *** institution with the most articles was Nanjing *** their credit,three of the top 10 most cited articles were written by Chinese *** keyword co-occurrence map showed that"oxidative stress","NRF2","activation","expression"and"brain"were the five most frequently used *** Research on the role of NRF2 in neurological diseases continues *** in developed countries published more influential papers,while Chinese scholars provided the largest number of a

关键词： Nuclear factor erythroid 2-related factor 2 Nervous system diseases Brain Expression Activation Ferroptosis

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Twenty years of changes in the disease assessment method of the Global Initiative for Chronic Obstructive Lung Disease

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Chinese Medical Journal 2020年第17期133卷 2098-2103页

作者： yi-xuan Liao Ya-Hong Chen Department of Pulmonary and Critical Care Medicine Peking University Third HospitalBeijing 100191China Department of Pulmonary and Critical Care Medicine Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China

The Global Initiative for Chronic Obstructive Lung Disease(GOLD)has been changing for nearly 20 *** has moved from single assessment using spirometry to a more comprehensive assessment of chronic obstructive pulmonary disease using spirometry,symptoms and exacerbation *** subsequently,a new assessment system for chronic obstructive pulmonary disease separated spirometric grades from the old assessment system,and classified patients only according to their symptoms and history of *** distribution,clinical characteristics,treatment,and prognosis of the new subgroups were different from the old *** this review,we will present a brief profile of changes made to the disease assessment method of GOLD,based on the relevant existing literature.

关键词： Chronic obstructive pulmonary disease Global Initiative for Chronic Obstructive Lung Disease Disease assessment method

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Free radicals trigger the closure of open pores in lignin-derived hard carbons toward improved sodium-storage capacity

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Journal of Energy Chemistry 2024年第7期94卷 551-559页

作者： Wen-Jun Ji Zong-Lin yi Ming-Xin Song Xiao-Qian Guo yi-Lin Wang yi-xuan Mao Fang-Yuan Su Jing-Peng Chen Xian-Xian Wei Li-Jing Xie Cheng-Meng Chen CAS Key Laboratory of Carbon Materials Institute of Coal ChemistryChinese Academy of SciencesTaiyuan 030001ShanxiChina University of Chinese Academy of Sciences Beijing 100049China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China School of Environment and Safety Taiyuan University of Science and TechnologyTaiyuan 030001ShanxiChina

The chemical activation of various precursors is effective for creating additional closed pores in hard carbons for sodium ***,the formation mechanism of closed pores under the influence of pore-forming agents is not well ***,an effective chemical activation followed by a high-temperature self-healing strategy is employed to generate interconnected closed pores in lignin-derived hard carbon(HCs).By systematic experimental design combined with electron paramagnetic res-onance spectroscopy,it can be found that the content of free radicals in the carbon matrix influences the closure of open pores at high *** high activation temperature(>700 C)leads to a low free radical concentration,making it difficult to achieve self-healing of open pores at high *** activation at 700°C,a balance between pore making and self-healing is achieved in the final hard carbon.A large number of free radicals triggers rapid growth and aggregation of carbon microcrys-tals,blocking pre-formed open micropores and creating additional interconnected closed pores in as-obtained hard *** a result,the optimized carbon anode(LK-700-1300)delivers a high reversible capacity of 330.8 mA h g^(-1) at 0.03 A g^(-1),which is an increase of 86 mA h g^(-1) compared to the pristine lignin-derived carbon anode(L-700-1300),and exhibits a good rate performance(202.1 mA h g^(-1) at 1 A g^(-1)).This work provides a universal and effective guidance for tuning closed pores of hard carbons from otherprecursors.

关键词： Hard carbon Chemical activation Free radical Self-healing Closed pores Sodium ion batteries

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Comparative Study of the Magnetic Properties and Glass-Forming Ability of Fe-Based Bulk Metallic Glass with Minor Mn, Co, Ni, and Cu Additions

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Acta Metallurgica Sinica(English Letters) 2016年第9期29卷 834-839页

作者： Md Anisur Rahman Yun-Zhuo Lu Qiang Luo Shou-Jiang Qu Feng-Xia Ye yi-xuan Wu Jun Shen School of Materials Science and Engineering Tongji University School of Materials Science and Engineering Dalian Jiaotong University

Fe43MsCra5Mo14C15B6Y2 （M = Mn, Co, Ni, and Cu in at.%） bulk metallic glasses （BMGs） are synthesized using the suction casting technique, and the glass-forming ability （GFA）, microstructure, and thermal and magnetic properties of these glasses are extensively examined using X-ray diffraction, differential scanning calorimeter, and vibrating sample magnetometer techniques. Among the four BMG alloys, Fe43NisCr15Mo14C15B6Y2 exhibits the lowest coercivity and the highest saturation magnetization, Curie temperature, effective magnetic moment, and GFA. By contrast, Fe43MnsCrlsMo14C15B6Y2 presents the poorest magnetic properties, such as the highest coercivity and the lowest saturation magnetization, Curie temperature, and effective magnetic moment. Fe43Cu5Cr15MolaC15B6Y2 demonstrates the lowest thermal stability and GFA. The observed thermal, structural, and magnetic properties of these BMG alloys are discussed in terms of the kinetics of BMG synthesization and the formation of different ferromagnetic, ferrimagnetic, and antiferromagnetic phases.

关键词： Bulk metallic glasses Saturation magnetization Effective magnetic moment Coercivity Glass-forming ability

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Aquaculture species diversification in China

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Aquaculture and Fisheries 2024年第2期9卷 206-217页

作者： Gen Hua Yue yi xuan Tay Joey Wong Yubang Shen Junhong Xia Temasek Life Sciences Laboratory National University of Singapore1 Research Link117604Singapore Key Laboratory of Freshwater Aquatic Genetic Resources Ministry of Agriculture and Rural AffairsShanghai Ocean UniversityShanghai201306China State Key Laboratory of Biocontrol Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic AnimalsCollege of Life SciencesSun Yat-Sen UniversityGuangzhou510275China

China has been the top aquaculture producer in the world since *** 800 species and 240 improved varieties have been used in China’s aquaculture,which is the most diverse collection of species on this *** diversification,along with other aquaculture technologies,contributes significantly to the increase of China’s aquaculture production,whereas the use of too many species in aquaculture has resulted in some issues related to the environment and *** provide an updated overview of the species currently used in Chinese aquaculture in this *** examine critically the main drivers of species diversification in China with *** also introduce Chinese approaches to improve and certify new species and varieties for commercial *** believe that further species diversification is not a priority in China’s aquaculture,while further improvement of aquaculture technologies for major and native species is essential for green,profitable,and sustainable(GPS)*** implications of China’s experiences with species diversification for global aquaculture species diversification are discussed.

关键词： Fish Species Diversification Improvement Future

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Geometrical quasi-ballistic effects on thermal transport in nanostructured devices

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Nano Research 2021年第4期14卷 945-952页

作者： Sami Alajlouni Albert Beardo Lluc Sendra Amirkoushyar Ziabari Javier Bafaluy Juan Camacho yi xuan F.Xavier Alvarez Ali Shakouri Birck Nanotechnology Center Purdue UniversityWest LafayetteIndiana 47907USA Department of electrical and computer engineering Purdue UniversityWest LafayetteIndiana 47907USA Department of physics Universitat Autonoma de BarcelonaBellaterra 08193CataloniaSpain Oak Ridge National Laboratory Oak RidgeTennessee 37831USA R&D Staff Scientist ImagingSignals and Machine LearningTennessee 37831USA

We employ thermoreflectance thermal imaging to directly measure the steady-state two-dimensional(2D)temperature field generated by nanostructured heat sources deposited on silicon substrate with different geometrical configurations and characteristic sizes down to *** analysis of the results using Fourier's law not only breaks down as size scales down,but it alsofails to capture the impact of the geometry of the heat *** substrate effective Fourier thermal conductivities fitted to wire-shaped and circular-shaped structures with identical characteristic lengths are found to display up to 40%***,a hydrcxjynamic heat transport model reproduces the observed temperature fields for all device sizes and shapes using just intrinsic Si parameters,i.e.,a geometry and size-independent thermal conductivity and nonlocal length *** hydrodynamic model provides insight into the observed thermal response and of the contradictory Fourier *** discuss the substantial Silicon hydrodynamic behavior at room temperature and contrast it to InGaAs,which shows less hydrodynamic effects due to dominant phonon-impurity scattering.

关键词： phonon hydrodynamics nanoscale heat transfer quasi-ballistic transport silicon

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Spectral Property and Thermal Quenching Behavior of Tb^(3+)-Doped YAG:Ce Phosphor

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Chinese Journal of Structural Chemistry 2016年第2期35卷 326-334页

作者： GUO Wang SHI Hong-Ling HUANG Ji-Quan DENG Zhong-Hua YUAN xuan-yi CAO Yong-Ge Beijing Key Laboratory of Opto-electronic Functional Materials & Micro-nano Devices Renmin University of China Key Lab of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of Sciences

A series of YAG：Ce,Tb phosphors were synthesized by vacuum sintering ***,their spectral properties,thermal quenching behaviors and color rendering properties were investigated *** photoluminescence emission spectra of YAG：Ce,Tb show a great red shift compared with that of YAG：*** energy transfer from Tb^（3＋） to Ce^（3＋） ions is verified based on the analysis of different photoluminescence *** quenching temperature for Tb^（3＋）-doped YAG：Ce phosphors is about 490 *** thermal activation energy is estimated to be 0.18 and 0.291 eV for Tb^（3＋）-doped YAG：Ce and YAG：Ce phosphors,*** smaller activation energy for Tb^（3＋）-doped YAG：Ce means a more rapid nonradiative transition from 5d to 4f state,thus resulting in the lower quenching *** addition,white LEDs with improved color rendering properties are achieved by using modified YAG：Ce,Tb phosphors.

关键词： YAG:Ce Tb phosphors spectra properties thermal quenching white LEDs

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Disclosing the active integration structure and robustness of a pseudo-tri-component electrocatalyst toward alkaline hydrogen evolution

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Journal of Energy Chemistry 2022年第9期31卷 210-216,I0007页

作者： Hong-Hong Zou Wan-Qing Li Cong-Hu Song Li-Ming Cao Xue-Feng Zhang xuan-yi Zhu Zi-yi Du Jia Zhang Sheng-Liang Zhong Chun-Ting He Key Lab of Fluorine and Silicon for Energy Materials and Chemistry of Ministry of Education and College of Life ScienceJiangxi Normal UniversityNanchang 330022JiangxiChina Research Center for Ultrafine Powder Materials College of Chemistry and Chemical EngineeringJiangxi Normal UniversityNanchang 330022JiangxiChina

Designing multicomponent integration catalysts(MICs)has been a promising strategy for improving electrocatalytic hydrogen evolution reaction(HER)due to the highly active interfaces as well as electronic ***,many fundamental questions such as their actual active species and the influence on long-term stability remain to be ***,we present the structural evolution from a pseudotri-component electrocatalyst of nitrogen-doped carbon supported nickel/vanadium nitride/vanadium oxide(Ni-VN-V_(2)O_(3)/NC)nanorods to the heterostructural nickel/vanadium nitride(Ni-VN/NC)nanosheets during chemical or electrochemical *** self-reconstructed Ni-VN/NC exhibits a robust stability under alkaline conditions,while maintaining initial efficient HER activity with a low overpotential of 76 mV at the current density of 10 mA cm^(-2).Theoretical calculations and quasi-in-situ spectroscopic technology unveil the redistribution of electrons on the synergistic active interface,which synchronously optimizes the affinities for hydrogen,hydroxide,and water molecules,thereby remarkably accelerating the HER kinetics by reducing the barrier of Volmer step.

关键词： Hydrogen evolution reaction Multicomponent integration catalysts Structural transformation Electrocatalysis Density functional theory

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Narrow-bandgap materials for optoelectronics applications

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Frontiers of physics 2022年第1期17卷 89-121页

作者： Xiao-Hui Li yi-xuan Guo Yujie Ren Jia-Jun Peng Ji-Shu Liu Cong Wang Han Zhang School of Physics&Information Technology Shaanxi Normal UniversityXi’an710119China Shenzhen Key Laboratory of Two-Dimensional Materials and Devices/Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics Collaborative Innovation Center for Optoelectronic Science and TechnologyKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and GuangdongShenzhen518060China

Narrow-bandgap materials possess the intriguing optical-electric properties and unique structures,which can be widely applied in the field of photonics,energy optoelectronic sensing and biomedicine,***,the researches on nonlinear optical properties of narrow-bandgap materials have attracted extensive attention *** this paper,we review the progress of narrow-bandgap materials from many aspects,such as background,nonlinear optical properties,energy band structure,methods of preparation,and *** materials have obvious nonlinear optical characteristics and the interaction with the short pulse laser excitation shows the extremely strong nonlinear absorption characteristics,which leads to the optical limiting or saturable absorption related to Pauli blocking and excited state ***,some of these novel narrow-bandgap materials have been utilized for the generation of ultrashort pulse that covers the range from the visible to mid-infrared wavelength ***,the study on these materials paves a new way for the advancement of optoelctronics devices.

关键词： narrow-bandgap materials saturable absorber ultrafast lasers modulator photodetectors

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Effect of high magnetic field on solidification microstructure evolution of a Cu-Fe immiscible alloy

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China Foundry 2022年第4期19卷 335-341页

作者： Yu-jie Yan Chen Wei yi-xuan He Chao Li Ping-xiang Zhang Jin-shan Li Jun Wang State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi'an 710072China Xi'an Superconducting Magnet Technology Co. Ltd.Xi'an 710018China Northwest Institute for Nonferrous Metal Research Xi'an 710016China

The liquid phase separation behavior and the evolution of the solidification microstructure of a binary Cu_(50)Fe_(50) alloy were investigated under the conditions of without and with a 10 T magnetic field,with different undercooling during the solidification *** show that the combined effect of Stokes motion and Marangoni convection leads to the formation of the core-shell structure under the condition without the magnetic *** addition,specific gravity segregation is reinforced by increasing the undercooling,resulting in Fe-rich phase drifts towards the sample *** the 10 T magnetic field,the Fe-rich phase is elongated in the parallel direction of the magnetic field under the action of demagnetization energy due to the difference of static magnetic energy and surface *** the vertical direction,through the action of Lorentz force,the convection in the melt is inhibited and Fe-rich phase becomes more ***,the diffusion of the two phases and the coagulation of the Fe-rich phases are also restrained under the magnetic field,therefore,the phase volume fraction of the Fe-rich phase decreases at the same undercooling in the 10 T magnetic *** magnetic field inhibits the segregation behavior in the vertical direction of the magnetic field,and at the same time,improves the gravitational segregation to a certain extent,which has a very important impact on microstructure regulation.

关键词： high magnetic field Cu-Fe immiscible alloy undercooling solidification

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