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A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

signal Transduction and Targeted Therapy 2021年第3期6卷 779-794页

作者： kang Sun yi-yuan Li Jin Jin MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences InstituteZhejiang UniversityHangzhou 310058China Key Laboratory for Developmental Genes and Human Disease Ministry of EducationInstitute of Life SciencesJiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjing 210096China sir Run Run Shaw Hospital College of Medicine Zhejiang UniversityHangzhou 310016China

The response of immune cells in cardiac injury is divided into three continuous phases:inflammation,proliferation and *** kinetics of the inflammatory and proliferation phases directly influence the tissue *** cardiac homeostasis,cardiac tissue resident macrophages(cTMs)phagocytose bacteria and apoptotic ***,NK cells prevent the maturation and transport of inflammatory *** cardiac injury,cTMs phagocytose the dead cardiomyocytes(CMs),regulate the proliferation and angiogenesis of cardiac progenitor *** cells prevent the cardiac fibrosis,and promote vascularization and *** 1 macrophages trigger the cardioprotective responses and promote tissue fibrosis in the early ***,type 2 macrophages promote cardiac remodeling and angiogenesis in the late *** macrophages and neutrophils firstly lead to chronic inflammation by secreting proinflammatory cytokines,and then release anti-inflammatory cytokines and growth factors,which regulate cardiac *** this process,dendritic cells(DCs)mediate the regulation of monocyte and macrophage *** eosinophils and Mast cells(MCs)release some mediators which contribute to coronary vasoconstriction,leukocyte recruitment,formation of new blood vessels,scar *** adaptive immunity,effector T cells,especially Th17 cells,lead to the pathogenesis of cardiac fibrosis,including the distal fibrosis and scar *** protectors,Treg cells,inhibit reduce the inflammatory response,then directly trigger the regeneration of local progenitor cell via IL-10.B cells reduce myocardial injury by preserving cardiac function during the resolution of inflammation.

关键词： cardiac homeostasis inflammation

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Study on inverter fault-tolerant operation of PMSM DTC

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第2期9卷 156-164页

作者： Yznaga Blanco IVONNE Dan SUN yi-kang HE School of Electrical Engineering Zhejiang University Hangzhou 310027 China Researches and Electrical Tests Center Cujae University Havana City 19390 Cuba

This paper presents an investigation of inverter fault-tolerant operation for a permanent magnet synchronous motor （PMSM） direct torque control （DTC） system under various inverter faults. The performance of a faulty standard 6-switch inverter driven PMSM DTC system is analyzed. To avoid the loss or even disaster caused by the inverter faults, a topology-modified inverter with fault-tolerant capability is introduced, which is reconfigured as a 3-phase 4-switch inverter. The modeling of the 4-switch inverter is then analyzed and a novel DTC strategy with a unique nonlinear perpendicular flux observer and feedback compensation scheme is proposed for obtaining a continuous, disturbance-flee drive system. The simulation and experimental results demonstrate that the proposed inverter fault-tolerant PMSM DTC system is able to operate stably and continuously with acceptable static and pretty good dynamic performance.

关键词： Permanent magnet synchronous motor (PMSM) Direct torque control (DTC) Fault-tolerant operation Four-switchinverter Nonlinear perpendicular flux observer

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SENsiTIVE NUMERICAL siMULATION AND ANALYsiS OF RAINSTORM UsiNG NESTED WRF MODEL

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Journal of Hydrodynamics 2006年第5期18卷 578-586页

作者： WANG Shu-chang HUANG si-xun LI yi Institute of Meteorology PLA University of Science and Technology Nanjing 211101 China

Nowadays, the nested grid model is widely used to increase the resolution of numerical model. An attempt to investigate the influence of the newly developed nesting technique of WRF model on the mesoscale numerical simulation of severe storm is described in this article. The results of sensitivity tests infer that the WRF model give more accurate and vivid prediction of severe storm with nesting scheme. As is shown in the tests, simulating value of the precipitation centers using nesting scheme are larger than those without using nesting scheme, which indicates that the simulating precipitation of nested storm is closer to the real rainfall. And there is obvious improvement of distribution of rain area and position of precipitation centers. According to the high resolution output data of the WRF model, deep and detailed analysis of characters of the mesoscale system that triggers the rainstorm is reported in this article, and the thermal and dynamical characters of this Meiyu front severe storm are also discussed.

关键词： WRF nesting numerical simulation mesoscale analysis

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Dynamic modeling and direct power control of wind turbine driven DFIG under unbalanced network voltage conditions

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第12期9卷 1731-1740页

作者： Jia-bing HU yi-kang HE Lie XU School of Electrical Engineering Zhejiang University Hangzhou 310027 China Department of Electronics and Electrical Engineering University of Strathclyde Glasgow G40PG UK

This paper proposes an analysis and a direct power control (DPC) design of a wind turbine driven doubly-fed induction generator (DFIG) under unbalanced network voltage conditions. A DFIG model described in the positive and negative synchronous reference frames is presented. Variations of the stator output active and reactive powers are fully deduced in the presence of negative sequence supply voltage and rotor flux. An enhanced DPC scheme is proposed to eliminate stator active power oscillation during network unbalance. The proposed control scheme removes rotor current regulators and the decomposition processing of positive and negative sequence rotor currents. simulation results using PSCAD/EMTDC are presented on a 2-MW DFIG wind power generation system to validate the feasibility of the proposed control scheme under balanced and unbalanced network conditions.

关键词： Doubly-fed induction generator (DFIG) Wind turbine Direct power control (DPC) Stator voltage oriented (SVO) Unbalanced network

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Controlled synthesis and closed-loop chemical recycling of biodegradable copolymers with composition-dependent properties

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Science China Chemistry 2022年第5期65卷 943-953页

作者： yi-Teng Yan Gang Wu si-Chong Chen Yu-Zhong Wang The Collaborative Innovation Center for Eco-Friendly and Fire-Safety Polymeric Materials(MoE) National Engineering Laboratory ofEco-Friendly Polymeric Materials(Sichuan)State Key Laboratory of Polymer Materials EngineeringCollege of ChemistrySichuan UniversityChengdu 610064China

The closed-loop recycling concept of the polymer wastes into building-block chemicals is attractive,but the closed-loop recycling of copolymers enabled by energy-efficient chemical recycling and cost-effective separations is still facing great ***,for the first time,a one-pot sequential copolymerization of γ-butyrolactone(γ-BL) and p-dioxanone(PDO)using an economical ureas/alkoxides catalytic system is conducted to synthesize biodegradable and chemically recyclable poly-(γ-butyrolactone)-block-poly(p-dioxanone)(PγBL-b-PPDO) diblock copolymers with well-defined and controlled *** composition-dependent properties of PγBL-b-PPDO copolymers,including thermal properties and crystallization behavior,are *** results show that the thermal stability and crystalline ability of PγBL are enhanced observably by introducing the PPDO ***,the PγBL-b-PPDO copolymers can be depolymerized efficiently into the corresponding co-monomers with a yield of over 95% by simply low-temperature pyrolysis under ***,γ-BL and PDO monomers are selectively separated with an isolated purity of about 99% based on the difference in their physicochemical ***,their repolymerization is realized to obtain the copolymers with nearly identical structures and thermostability,demonstrating the closed-loop recycling of copolymers,i.e.,*** research provides important guidance for the design of novel sustainable polymers towards more efficient chemical recycling,separation and regeneration.

关键词： biodegradable copolyester poly(p-dioxanone) tunable properties closed-loop chemical recycling

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Enhanced control of DFIG-used back-to-back PWM VSC under unbalanced grid voltage conditions

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第8期8卷 1330-1339页

作者： HU Jia-bing HE yi-kang NIAN Heng School of Electrical Engineering Zhejiang University Hangzhou 310027 China

This paper presents a unified positive-and negative-sequence dual-dq dynamic model of wind-turbine driven doubly-fed induction generator(DFIG) under unbalanced grid voltage conditions. Strategies for enhanced control and operation of a DFIG-used back-to-back(BTB) PWM voltage source converter(VSC) are proposed. The modified control design for the grid-side converter in the stationary αβ frames diminishes the amplitude of DC-link voltage ripples of twice the grid frequency,and the two proposed control targets for the rotor-side converter are alternatively achieved,which,as a result,improve the fault-ride through(FRT) capability of the DFIG based wind power generation systems during unbalanced network supply. A complete unbalanced control scheme with both grid-and rotor-side converters included is designed. Finally,simulation was carried out on a 1.5 MW wind-turbine driven DFIG system and the validity of the developed unified model and the feasibility of the proposed control strategies are all confirmed by the simulated results.

关键词： Unbalanced grid voltage Doubly-fed induction generator (DFIG) Back-to-back (BTB) Fault-ride through (FRT) Voltage source converter (VSC)

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Mn3O4/carbon nanotube nanocomposites recycled from waste alkaline Zn–MnO2 batteries as high-performance energy materials

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Rare Metals 2017年第5期36卷 442-448页

作者： Li-Hua Zhang si-si Wu yi Wan yi-Feng Huo Yao-Cong Luo Ming-Yang Yang Min-Chan Li Zhou-Guang Lu Laboratory of Green and Renewable Energy Materials Department of Materials Science and EngineeringSouth University of Science and Technology of ChinaShenzhenChina

Alkaline zinc manganese dioxide（Zn–MnO2）batteries are widely used in everyday life. Recycling of waste alkaline Zn–MnO2 batteries has always been a hot environmental concern. In this study, a simple and costeffective process for synthesizing Mn3O4/carbon nanotube（CNT） nanocomposites from recycled alkaline Zn–MnO2 batteries is presented. Manganese oxide was recovered from spent Zn–MnO2 battery cathodes. The Mn3O4/CNT nanocomposites were produced by ball milling the recovered manganese oxide in a commercial multi-wall carbon nanotubes（MWCNTs） solution. Scanning electron microscopy（SEM） analysis demonstrates that the nanocomposite has a unique three-dimensional（3D） bird nest structure. Mn3O4 nanoparticles are homogeneously distributed on MWCNT framework. Mn3O4/CNT nanocomposites were evaluated as an anode material for lithium-ion batteries, exhibiting a highly reversible specific capacitance of -580 mA h·g^-1 after 100 cycles. Moreover, Mn3O4/CNT nanocomposite also shows a fairly positive onset potential of -0.15 V and quite high oxygen reducibility when considered as an electrocatalyst for oxygen reduction reaction.

关键词： Waste Zn–MnO2 batteries Recycling Nanocomposites Anode materials Oxygen reduction reaction

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Electrolytic alloy-type anodes for metal-ion batteries

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Rare Metals 2021年第2期40卷 329-352页

作者： Xian-Yang Li Jia-kang Qu Hua-yi yin Key Laboratory for Ecological Metallurgy of Multimetallic Mineral of Ministry of Education School of MetallurgyNortheastern UniversityShenyang110819China Key Laboratory of Data Analytics and Optimization for Smart Industry Ministry of EducationNortheastern UniversityShenyang110819China

Alloy-type metals/alloys hold the promise of increasing the energy density of metal-ion batteries(MIBs)because of their theoretical high gravimetrical *** and semimetal-analogs are typical alloy-type ***,the large-scale extraction of semimetals(si,Ge)and semimetal-analogs(Sb,Bi,Sn)by traditional metallurgical routes highly relies on using reducing agents(e.g.,carbon,hydrogen,reactive metals),which consumes a large number of fossil fuels and produces greenhouse gas *** addition,the common metallurgical methods for extracting semimetals involve relatively high operating temperatures and therefore produce bulk metal ingots solidified from the liquid ***,the commonly used electrode materials in batteries are fine ***,directly producing semimetal powders would be more energy *** addition,semimetals are good candidates to host alkali/alkaline-earth ions through the alloying process because the electronegativity of semimetals is ***,preparing semimetal powders via an environment-sound manner is of great interest to provide sustainable anode materials for MIBs while reducing the ecological ***-cost and high-output capacity anode powder materials,as well as straightforward and environmental-benign synthetic methods,play key roles in enabling the energy conversion and storage technologies for real applications of *** technologies offer new strategies to extract semimetals using electrons as the reducing agent that comes from renewable ***,the morphologies and structures of the electrolytic products can be rationally tailored by tuning the electrode potentials,electrolytes,and operating *** this regard,using the one-step green electrochemical method to prepare high-capacity and cheaper alloy-type metalloids for MIB anodes can fulfill the requirements for developing *** review critically overviews recent developments and advances in the elect

关键词： Electrochemical extraction Alloy-type anodes Metal-ion batteries Manufacture strategies Morphologies and structures

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Quantitative evaluation of the contribution of underground space to urban resilience:A case study in China

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Underground Space 2024年第4期17卷 1-24页

作者： si-Cong Liu Fang-Le Peng Yong-kang Qiao Yun-Hao Dong Research Center for Underground Space&Department of Geotechnical Engineering Tongji UniversityShanghai 200092China

Urban underground space(UUS)development has been acknowledged as a positive contribution to urban resilience(UR).Such contribution has been qualitatively addressed in recent years,but only quantitatively discussed in few *** evaluation methods for UR are widely used in China and around the world,but the role of underground space is barely *** paper provides a way to bridge this gap on the city scale.A UR evaluation framework was carefully constructed that covers the basic aspects and elements of *** contributions of UUS to UR were identified and integrated into the UR evaluation framework,and the measurement methods for each indicator related to UUS were determined.A case study of 19 sample cities in China were conducted using the integrated evaluation *** analysis and clustering analysis were further adopted to interpret the evaluation results,mainly with three indicators reflecting the level of UUS development,namely UUS area(m^(2)),UUS density(104 m^(2)/km^(2))and UUS area per capita(m^(2)/person).The results showed a strong correlation between UUS area and *** average proportion of UR provided by UUS in the 19 sample cities was 16.46%,while the maximum figure reached 29.20%.The sample cities were clustered into four categories based on the relationship between the proportion of UR provided by UUS,UUS area,and GDP per capita,where both high and low UUS area tend to provide less proportion of resilience than the medium UUS *** suggestions for UUS utilization were proposed to assist cities in achieving urban resilience.

关键词： Urban underground space(UUS) Urban resilience Resilience evaluation Resilient development

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Mechanical behavior study of microdevice and nanomaterials by Raman spectroscopy:a review

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Chinese Science Bulletin 2014年第23期59卷 2811-2824页

作者： Wei Qiu yi-Lan kang Tianjin Key Laboratory of Modern Engineering Mechanics Department of MechanicsTianjin University

With the rapid development of micro/nano manufacturing technology and nanomaterials,the accurate measurement of the mechanical properties and behaviors at the micro-nano scale represents a new field of mechanical *** spectroscopy,which is based on lattice dynamics theory,is applicable to the detection of the statistical information of the lattice structure deformation within the measuring *** to its peculiarities,such as non-destructiveness,convenience and high-resolution,this technology allows the on-line in situ measurement of residual stress in microstructures caused by processing and can also achieve the real-time deformation of graphene,carbon nanotubes and other nanomaterials under force *** recent years,mechanical measurements based on Raman spectroscopy technology have developed *** this review,Raman-based stress measurement theories for several commonly used materials are briefly *** related to the residual stress measurements of microstructure and experimental investigations of the mechanical properties of low-dimensional nanomaterials are then ***,the development trend of this method is proposed.

关键词：拉曼光谱仪动力学理论纳米材料行为研究纳米制造技术残余应力测量展望微型

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