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Enhancement of Selectivity in Capillary Zone Electrophoresis by Adding Ethanolamines or Ethylamines in the Running Buffer

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Chinese Chemical Letters 1997年第11期8卷 985-988页

作者： yi yang dong Ai Jin HUANG yi Liang SUN(Department of Chemistry Peking University Beijing 100871) Beijing Univ Dept Chem Beijing 100871 Peoples R China

Mono-, di-, tri-ethanolamines and di-, tri-ethylamines were used to prepare phosphate buffer at pH 2.5 and shown to be capable of enhancing the separation selectivity of chiral drug pinacidil and melittin in bee venom in capillary zone electrophoresis. The reason is due to the reduction of the average apparent mobilities of the analytes.

关键词： Enhancement of Selectivity in Capillary Zone Electrophoresis by Adding Ethanolamines or Ethylamines in the Running Buffer

Assessing clogging potential and optimizing driving parameter of slurry shield tunneling in clay stratum assisted with CFD-DEM modeling

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Underground Space 2024年第1期14卷 197-218页

作者： yi yang Xing-gao Li Han-yuan Li yi-dong Guo ying-ran Fang Key Laboratory of Urban Underground Engineering of the Education Ministry Beijing Jiaotong UniversityBeijing 100044China School of Civil Engineering Beijing Jiaotong UniversityBeijing 100044China

This paper proposed a two-way coupled computational fluid dynamics(CFD)and discrete element method(DEM)approach to analyze the evolution of clogging in slurry shield tunneling *** interactions between clay particles and slurry were considered by exchanging three interaction forces,including buoyancy force,pressure gradient force,and drag *** CFD-DEM coupling approach was first benchmarked by comparing cutterhead torque and total thrust with field monitored data of a practical slurry shield tunnel *** evolution process of the particle phase and the fluid phase over time was *** results indicated that fewer than 70%of the particles can be washed away in time by the circulating *** 9%of the particles adhered to the submerged wall,resulting in increased cutterhead torque and *** parametric analysis,the influence of the shield driving parameters on the clay clogging behavior is further *** time history of cutterhead torque or thrust can be used as a criterion for judging whether clogging has ***,a new assessment method of clogging risk and an optimization strategy of driving parameters were proposed,which were intended to provide some guidance for similar projects.

关键词： Slurry shield Clogging Driving parameter optimization Assessment method CFD-DEM

MicroR-9c-5p and novel-mir50 co-target Akt to regulate Lasioderma serricorne reproduction

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Insect Science 2024年第1期31卷 106-118页

作者： yi Yan dong-dong Qin Hong yang Kang-Kang Xu Can Li Wen-Jia yang Provincial Key Laboratory for Agricultural Pest Management of Mountainous Region Institute of EntomologyGuizhou UniversityGuiyangChina Guizhou Provincial Key Laboratory for Rare Animal and Economic Insect of the Mountainous Region College of Biology and Environmental EngineeringGuiyang UniversityGuiyangChina

High fecundity is a common characteristic of insect pests which increases the difficulty of population ***/threonine kinase Akt is an indispensable component of the insulin signaling *** of LsAkt severely hinders reproduction in Lasioderma serricorne,a stored product insect ***,the post-transcriptional pathway of LsAkt in *** remains *** study identified 2 binding sites of miR-9c-5p and novel-mir50 in the coding sequences of *** expression profiles of 2 microRNAs(miRNAs)and LsAkt displayed an opposite pattern during the adult *** reporter assay showed that novel-mir50 and miR-9c-5p could downregulate the expression of *** of miR-9c-5p and novel-mir50 by injection of mimics inhibited the expression of LsAkt and reduced oviposition,decreased egg hatchability,and blocked ovarian *** also decreased the expression of genes involved in ovarian development(LsVg and LsVgR)and the nutritional signaling pathway(LsTOR,LsS6K,and Ls4EBP),and reduced the phosphorylation of ***,injection of miR-9c-5p and novel-mir50 inhibitors induced the expressions of LsAkt,LsVg,LsVgR,LsTOR,LsS6K,and Ls4EBP,enhanced Akt phosphorylation level,and accelerated ovarian *** of bovine insulin downregulated the expression of miR-9c-5p and novel-mir50 and upregulated the LsAkt *** also rescued the reproductive development defects associated with miR-9c-5p/novel-mir50 overexpression,forming a positive regulatory loop of insulin *** results indicate that miR-9c-5p/novel-mir50 regulates the female reproduction of *** by targeting Akt in response to insulin *** data also demonstrate the effects of the insulin/miRNA/Akt regulatory axis in insect reproduction.

关键词： Akt insulin Lasioderma serricorne microRNA reproduction

Deep decalcification of factory-provided freezing acidolysis solution to achieveα-high-strength gypsum

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Chinese Journal of Chemical Engineering 2024年第5期69卷 143-151页

作者： Wencai Ye Yulu Li Yonggang dong Lin yang Yun yi Jianxin Cao School of Chemistry and Chemical Engineering Guizhou UniversityGuiyang 550025China Engineering Research Center of Efficient Utilization for Industrial Waste Guizhou UniversityGuiyang 550025China Key Laboratory of Guizhou Province for Green Chemical Industry and Clean Energy Technology Guizhou UniversityGuiyang 550025China

The freezing acidolysis solution of the nitric acid-phosphate fertilizer process has a high calcium content,which makes it difficult to produce fine phosphate and high water-soluble phosphate fertilizer ***,based on the potential crystallization principle of calcium sulfate in NH_(4)NO_(3)-H_(3)PO_(4)-H_(2)O,the deep decalcification(*** removal)technology to achieveα-high-strength gypsum originated from freezing acidolysis-solutions has been firstly proposed and ***,calcium can be removed from the factory-provided freezing acidolysis-solution by neutralizing it with ammonia,followed by the addition of ammonium sulfate *** a result,the formation of calcium sulfate in the reaction system undergoes the nucleation and growth of CaSO_(4)·2H_(2)O(DH),as well as its dissolution and crystallization into short columnarα-CaSO_(4)·0.5H_(2)O(α-HH).Remarkably,with the molar ratio of SO_(4)^(2-)/Ca^(2+)at 1.8,the degree of neutralization(NH_(3)/HNO_(3) molar ratio)at 1.7,the reaction temperature of 94℃,and the reaction time of 300 min,the decalcification rate can reach 86.89%,of which the high-strengthα-CaSO_(4)·0.5H_(2)O(α-HH)will be ***,the deep decalcification product meets the standards for the production of fine phosphates and highly water-soluble phosphate ***,the 2 h flexural strength ofα-HH is 5.3 MPa and the dry compressive strength is 36.8 MPa,which is up to the standard of commercialα-HH.

关键词： Nitrophosphate Ammonia neutralization Deep decalcification High-strengthα-hemihydrate gypsum Controlled crystallization at atmospheric pressure

Impact of Air Pollutants on Lung Function and Inflammatory Response in Asthma in Shanghai

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Biomedical and Environmental Sciences 2024年第8期37卷 811-822页

作者： Guifang Wang Youzhi Zhang Haiyan yang yi yang Liang dong Peng Zhang Jie Liu Xiaodong Chen yi Gong Department of Respiratory and Critical Care Medicine Quzhou People's HospitalQuzhou 324000ZhejiangChina Department of Respiratory and Critical Care Medicine Huashan Hospital Affiliated to Fudan UniversityShanghai 200040China Centre of Hydrogen Science Shanghai Jiao Tong University&Key Lab of Hydrogen ScienceShanghai 200240China Department of Respiratory and Critical Care Medicine Shanghai Public Health Clinical CentreFudan UniversityShanghai 201508China

Objective Air pollution is a leading public health *** study investigated the effect of air quality and pollutants on pulmonary function and inflammation in patients with asthma in *** The study monitored 27 asthma outpatients for a year,collecting data on weather,patient self-management[daily asthma diary,peak expiratory flow(PEF)monitoring,medication usage],spirometry and serum *** explore the potential mechanisms of any effects,asthmatic mice induced by ovalbumin(OVA)were exposed to PM_(2.5).Results Statistical and correlational analyses revealed that air pollutants have both acute and chronic effects on *** exposure showed a correlation between PEF and levels of ozone(O_(3))and nitrogen dioxide(NO_(2)).Chronic exposure indicated that interleukin-5(IL-5)and interleukin-13(IL-13)levels correlated with PM_(2.5)and PM_(10)*** asthmatic mouse models,exposure to PM_(2.5)increased cytokine levels and worsened lung ***,PM_(2.5)exposure inhibited cell proliferation by blocking the NF-κB and ERK phosphorylation *** Ambient air pollutants exacerbate asthma by worsening lung function and enhancing Th2-mediated ***,PM_(2.5)significantly contributes to these adverse *** research is needed to elucidate the mechanisms by which PM_(2.5)impacts asthma.

关键词： Ambient air pollutants Acute and chronic effects on asthma PM_(2.5) OVA-induced asthmatic mice

Lowering the threshold of alanine aminotransferase for enhanced identification of significant hepatic injury in chronic hepatitis B patients

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世界胃肠病学杂志:英文版 2023年第35期29卷 5166-5177页

作者： Hong-Sheng Yu Hao Jiang Ming-Kai Li Bi-Lan yang Abdukyamu Smayi Jian-Ning Chen Bin Wu yi-dong yang Department of Gastroenterology The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510630Guangdong ProvinceChina Department of Liver Disease Guangdong Provincial Key Laboratory of Liver Disease ResearchGuangzhou 510630Guangdong ProvinceChina Department of Pathology The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510630Guangdong ProvinceChina

BACKGROUND The clinical and histological features of chronic hepatitis B(CHB)patients who fall into the"grey zone(GZ)"and do not fit into conventional natural phases are *** To explore the impact of varying the threshold of alanine aminotransferase(ALT)levels in identifying significant liver injury among GZ *** This retrospective analysis involved a cohort of 1617 adult patients diagnosed with CHB who underwent liver *** clinical phases of CHB patients were determined based on the European Association for the Study of the Liver 2017 Clinical Practice *** CHB patients were classified into four groups:GZ-A(HBeAg positive,normal ALT levels,and HBV DNA≤10^(7) IU/mL),GZ-B(HBeAg positive,elevated ALT levels,and HBV DNA10^(7) IU/mL),GZC(HBeAg negative,normal ALT levels,and HBV DNA≥2000 IU/mL),and GZ-D(HBeAg negative,elevated ALT levels,and HBV DNA≤2000 IU/mL).Significant hepatic injury(SHI)was defined as the presence of notable liver inflammation(≥G2)and/or significant fibrosis(≥S2).RESULTS The results showed that 50.22%of patients were classified as GZ,and 63.7%of GZ patients developed *** study also found that lowering the ALT treatment thresholds to the American Association for the Study of Liver Diseases 2018 treatment criteria(35 U/L for men and 25 U/L for women)can more accurately identify patients with significant liver damage in the GZ *** total,the proportion of patients with ALT≤40 U/L who required antiviral therapy was 64.86%[(221+294)/794].When we lowered the ALT treatment threshold to the new criteria(30 U/L for men and 19 U/L for women),the same outcome was revealed,and the proportion of patients with ALT≤40 U/L who required antiviral therapy was 75.44%[(401+198)/794].Additionally,the proportion of SHI was 49.1%in patients under 30 years old and increased to 55.3%in patients over 30 years old(P=0.136).CONCLUSION These findings suggest the importance of redefining the natural phases of CHB and using ne

关键词： Chronic hepatitis B Grey zone Indeterminate phase Alanine aminotransferase Antiviral therapy

Radiation construction and excellent performances of Ag NPs/TiO_(2)/PEG/PVP multifunctional aerogel:Adsorption-photocatalytic degradation,photosensitive antibacterial and cytotoxicity

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Journal of Materiomics 2024年第3期10卷 585-593页

作者： Jin-Yu yang dong-Liang Liu Yue-Sheng Li Xiao-Jie yang yi Liu School of Nuclear Technology and Chemistry&Biology/Hubei Key Laboratory of Radiation Chemistry and Functional Materials Hubei University of Science and TechnologyXianning437100HubeiChina Key Laboratory of Coal Conversion and New Carbon Materials of Hubei Province School of Chemistry and Chemical EngineeringWuhan University of Science and TechnologyWuhan437100HubeiChina College of Chemistry and Chemical Engineering Tiangong UniversityTianjin300387China

A cutting-edge method known as photocatalytic antibacterial technology can effectively eliminate drug-resistant bacterial strains and boast a wide-ranging antimicrobial *** the study,a novel Ag NPs/TiO_(2)/PEG/PVP(ATPP)aerogel photocatalyst was synthesized by an electron beam in-situ radiation method using polyethylene glycol(PEG),polyvinylpyrrolidone(PVP),AgNO_(3),and TiO_(2)as raw *** was characterized by X-ray diffraction spectroscopy(XRD),X-ray photoelectron spectroscopy(XPS)and solid ultraviolet diffuse reflectance spectroscopy(UV-Vis DRS).The results demonstrated that silver ions were reduced to silver nanoparticles by electron beam radiation *** the same time,the doping of silver nanoparticles(Ag NPs)enhanced visible-light *** degradation rate of methylene blue(MB)on 5%(in mass)ATPP could reach 81%under visible light for 180 *** coli(***)and Staphylococcus aureus(***)were used as model bacteria to explore the antimi-crobial properties of ATPP by zone of the inhibition method,plate counting method and live/dead bacterial *** antibacterial experiments showed that the antibacterial effect of ATPP was ***,MTT assay and Hoechst33342/PI double staining were used to prove that the composite had good *** aerogel photocatalytic material has the potential to decrease microbial presence in both medical and environmental settings,making it a valuable tool for such applications.

关键词： Ag NPs/TiO_(2)/PEG/PVP aerogel Electron beam radiation Adsorption-photocatalytic Photosensitive antibacterial Cytotoxicity

Poles Extraction Based LiDAR Localization for Autonomous Robot Systems

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Journal of Systems Science & Complexity 2024年第4期37卷 1413-1424页

作者： HONG Xin dong yi College of Electronic and Information Engineering Tongji UniversityShanghai 201800China

With the development of intelligent technology,the problem of Li DAR-based localization has played an increasingly important role in the localization of robots in unmanned *** the dense point clouds from the environment requires a large amount of memory,specific and stable structural features,such as pole-like objects in the environment,can serve as the ideal landmarks for localization in unmanned systems,which can effectively reduce the memory usage and mitigate the effects of dynamic environment *** this paper,the authors propose a pole-like objects extraction approach and then,it is applied into the localization system of mobile *** the same experimental conditions,the proposed method can extract more pole-like objects and achieve better long-term localization accuracy than some existing methods in different urban environmental datasets.

关键词： Pole-like landmark extraction robot localization

Fast Determination of the Rubber Content in Taraxacum kok-saghyz Fresh Biomass Using Portable Near-Infrared Spectroscopy and Pyrolysis-Gas Chromatography

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Journal of Analysis and Testing 2022年第4期6卷 393-400页

作者： ying Chen Shun-Kai Gao yi-yang dong Xiang Ma Jia-Ru Li Min-Min Guo Ji-Chuan Zhang College of Life Science and Technology Rubber Plant Research CenterBeijing University of Chemical TechnologyBeijing100029China College of Materials and Engineering Beijing University of Chemical TechnologyBeijing100029China

Taraxacum kok-saghyz(TKS)is a plant native to the Tianshan valley on the border between China and *** rubber is a good substitute for natural ***'s breeding work necessitates the need to screen high-yielding varieties,hence rapid determination of rubber content is essential for the *** analytical methods cannot meet actual needs in terms of real-time testing and economic ***-infrared spectroscopy analysis technology,which has developed rapidly in the field of industrial process analysis in recent years,is a green detection technology with obvious merits of fast measurement speed,low cost and no sample *** research aims to develop a portable non-destructive near-infrared spectroscopic detection scheme to evaluate the content of natural rubber in TKS fresh *** gas chromatography(Py-GC)was chosen as the reference method for the development of NIR prediction model.208 TKS fresh root samples were collected from the Inner Mongolia Autonomous Region of ***-infrared spectra were acquired for all ***,two-thirds of them were selected as the calibration set,the remaining one-third as the validation set,and the partial least squares method was successfully established a good NIR prediction model for rubber content at 1080-1800 nm with a ratio of performance to deviation(RPD)of 5.54 and coefficient of determination(R^(2))of *** study showed that portable near-infrared spectroscopy could be used with ease for large-scale screening of TKS plants in farmland,and could greatly facilitate TKS germplasm preservation,high-yield cultivation,environment-friendly,high-efficiency and low-cost rubber extraction,and comprehensive advancement of the natural rubber industry thereof.

关键词： Taraxacum kok-saghyz Rubber Near-infrared spectroscopy Pyrolysis gas chromatography