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Lipid levels and insulin resistance markers in patients with colorectal cancer:Propensity score matching analysis

World Journal of Gastrointestinal Oncology 2025年第1期17卷 130-142页

作者： Ren-Hao Hu Dong-yi yan Ke-Hui Zhang Di Zhang Xi-Mao Cui Xiao-Hua Jiang Shun Zhang Department of Gastrointestinal Surgery Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China School of Medicine Tongji UniversityShanghai 200092China Department of Emergency Medicine Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China

BACKGROUND Colorectal cancer(CRC)is a prevalent malignant neoplasm characterized by subtle early *** To investigate the correlation among serum lipid profiles,the triglyceride-glucose(TyG)index,and the atherosclerotic index(AI)in patients with ***,it explored the clinical diagnostic utility of combining serum lipids with cancer antigens in the context of *** A retrospective analysis encompassed 277 patients with CRC and 1034 healthy *** Following propensity score matching,patients with CRC exhibited significantly reduced levels of serum triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol,and low-density lipoprotein cholesterol(LDL-C),as well as a diminished TyG ***,they displayed elevated AI levels compared to their healthy *** in advanced stages exhibited lower serum levels of TG,TC,and LDL-C compared to those in early *** with positive lymph node metastasis demonstrated reduced levels of TG,LDL-C,and the TyG *** operating characteristic analysis revealed that the combination of the TyG index,carcinoembryonic antigen,and carbohydrate antigen 19-9 yielded the highest positive prediction rate for CRC at 75.3%.CONCLUSION Preoperative serum lipid profiles exhibit a robust association with patients with *** concurrent assessment of multiple serum lipids and cancer antigens effectively enhances the diagnostic accuracy for CRC.

关键词： Colorectal cancer Serum lipids Triglyceride-glucose index Atherosclerotic index Diagnostic marker

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PROMOTING SILTATION EFFECTS AND IMPACTS OF HENGSHA EAST SHOAL ON THE yanGTZE RIVER ESTUARY

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Journal of Hydrodynamics 2011年第5期23卷 649-659页

作者： XIE Jun yan yi-xin College of Harbor Coastal and Offshore Engineering Hohai University Nanjing 210098 China Shanghai Waterway Engineering Design and Consulting Co. Ltd Shanghai 200120 China

For the Hengsha East Shoal Promoting Siltation Project in the yangtze River Estuary, this work developed a formula for calculating sediment carrying capacity based on variable coefficients and a mathematical model for suspended sedimentation using variable saturation recovery coefficients. Not only does the model yield good verification, preferably give the hydrodynamics and the sediment concentration, but also reach a good agreement between the simulation results andlux by tide for studying the effect the measured topographical changes in the promoting siltation zone of the Hengsha East Shoal. Moreover, this article proposes a method for examing the net sediment tran- sportation fs of the project of promoting siltation and comparatively analyzes the current siltation of the Hengsha East Shoal and siltation mouth layouts, entrance widths, entrance bottom elevations, and the impact of the South Main Dike on promoting siltation through calculating the net sediment transportation flux by tide over the fixed bed and the direct movable bed numerical simulations. The results are in good agreement with each other, indicating that the method for calculating the net sedi- ment transportation flux by the tide is also useful for assessing the project in promoting siltation. Finally, we use the modeling results to analyze the water and sediment diversion ratios and the changes in silting and scouting in riverbeds and draw the conclusion that the completion of the Hengsha East Shoal Promoting Siltation Project would not adversely affect the yangtze River Estuary Deepwater Channel Project.

关键词： Hengsha East Shoal promoting siltation effects mathematical simulation sediment diversion ratio net sediment transportation flux

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Multi-objective quality control method for cold-rolled products oriented to customized requirements

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International Journal of Minerals,Metallurgy and Materials 2021年第8期28卷 1332-1342页

作者： yi-fan yan Zhi-min Lü Collaborative Innovation Center of Steel Technology University of Science and Technology BeijingBeijing 100083China

To deal with the increasing demand for low-volume customization of the mechanical properties of cold-rolled products, a two-way control method based on mechanical property prediction and process parameter optimization(PPO) has become an effective solution. Aiming at the multi-objective quality control problem of a company's cold-rolled products, based on industrial production data, we proposed a process parameter design and optimization method that combined multi-objective quality prediction and PPO. This method used the multi-output support vector regression(MSVR) method to simultaneously predict multiple quality indices. The MSVR prediction model was used as the effect verification model of the PPO results. It performed multi-process parameter collaborative design and realized the optimization of production process parameters for customized multi-objective quality requirements. The experimental results showed that, compared with the traditional single-objective quality prediction model based on support vector regression(SVR), the multi-objective prediction model could better take into account the coupling effect between process parameters and quality index, the MSVR model prediction accuracy was higher than that of the SVR, and the optimized process parameters were more capable and reflected the influence of metallurgical mechanism on the quality index,which were more in line with actual production process requirements.

关键词： customized production quality control multi-objective prediction multi-output support vector regression process parameter optimization

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Nonlinear Squeezed States and Multiplication Rule of Nonlinear Squeezing Operators Gained via Nonlinear Coherent State Representation and IWOP Technique

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Communications in Theoretical Physics 2005年第1X期44卷 137-142页

作者： FANHong-yi HEHai-yan DepartmentofMaterialScienceandEngineering UniversityofScienceandTechnologyofChinaHefei230026China

Using the nonlinear coherent state representation we derive nonlinear squeezed states and the multiplication rule of nonlinear squeezing operators. We find that the symplectic matrices multiplication rule in nonlinear coherent state projection operator representation maps into the multiplication rule of successive nonlinear squeezing *** technique of integral within an ordered product of operators plays an essential role in deriving the multiplication rule.

关键词：非线性连贯非线性挤压算子乘法规则偶对变换

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NUMERICAL SIMULATIONS OF NONLINEAR WAVE TRANSFORMATION AROUND WAVE-PERMEABLE STRUCTURE

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Journal of Hydrodynamics 2005年第6期17卷 699-703页

作者： Li Xi yan yi-xin Department of Ocean Engineering Hohai University Nanjing 210098 China

The problem of wave partial/full reflection and transmission by wave-permeable structure is approached by solving the shape-related function with focus on the understanding of wave attenuation. 2D depth averaged Boussinesq type wave equations are given with new damping item in simulating the nonlinear wave transmission through wave-permeable structure. 1D wave equation is examined to give the analytical expression of the absorbing coefficient, and is compared with laboratory data in flume to calibrate the coefficients, and the expression is applied directly in modified Boussinesq type equations. Compared with wave basin data for various incident wave conditions, the accurate predictions of combined diffraction refraction effects in simulating nonlinear wave going through wave-permeable breakwater in the engineering application can be obtained. It shows that wave-permeable breakwaters with proper absorbing effects can be used as an effective alternative to massive gravity breakwaters in reduction of wave transmission in shallow water.

关键词： Boussinesq equations wav-absorbing coeffieient wave permeable breakwaters

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Grey incidence clustering method based on multidimensional dynamic time warping distance

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Journal of Systems Engineering and Electronics 2017年第5期28卷 946-954页

作者： Jin Dai yi yan Yuhong He School of Software Engineering Chongqing University of Posts and Telecommunications

The traditional grey incidence degree is mainly based on the distance analysis methods, which is measured by the displacement difference between corresponding points between sequences. When some data of sequences are missing (inconsistency in the length of the sequences), the only way is to delete the longer sequences or to fill the shorter sequences. Therefore, some uncertainty is introduced. To solve this problem, by introducing three-dimensional grey incidence degree (3D-GID), a novel GID based on the multidimensional dynamic time warping distance (MDDTW distance-GID) is proposed. On the basis of it, the corresponding grey incidence clustering (MDDTW distance-GIC) method is constructed. It not only has the simpler computation process, but also can be applied to the incidence comparison between uncertain multidimensional sequences directly. The experiment shows that MDDTW distance-GIC is more accurate when dealing with the uncertain sequences. Compared with the traditional GIC method, the precision of the MDDTW distance-GIC method has increased nearly 30%.

关键词： grey incidence analysis (GIA) dynamic time warping (DTW) distance grey incidence clustering

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Effects of coal seam dip angle on the outburst in coal roadway excavation

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International Journal of Mining Science and Technology 2019年第5期29卷 757-764页

作者： Cheng Hou yinghua Zhang yi yan University of Science and Technology Beijing Beijing 100083China Department of Mechanical Engineering McGill UniversityMontrealQC H3A 0C3Canada

The prevention and forecast of coal and gas outburst has always been one of the key issues in coal mining *** simulating the process of tunneling in coal seam with different dip angle through FLAC3D software,the dangerous zone in which outburst may occur and the probability of outburst near the working face were predicted through the distribution of stress,displacement and plastic *** we discussed the size of unstable area in the surrounding rock through the distribution of stress and the variation curve of the displacement on the roadway *** results show that,with an increase of the coal seam dip angle,the risk of outburst in the working face rises *** the dangerous areas in which may outburst occur moves to the upper part of coal *** size of unstable area in the surrounding rock increases with the increase of coal seam dip angle.

关键词： Dip angle Stress concentration Plastic zone Displacement Coal and gas outburst

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Nanoparticles Study on the Indosinian Xiaomei Shear Zone in the Hainan Island,China:Implication to Developmental Stage and Formation Mechanism of Nanoparticles in a Fault Zone

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Journal of Earth Science 2020年第5期31卷 957-967页

作者： yang Zhou Baoyun Shen yi yan Hailing Liu yan yan Key Laboratory of Ocean and Marginal Sea Geology Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou 510640China University of Chinese Academy of Sciences Beijing 100049China Guangdong University of Technology Guangzhou 510006China South China Sea Institute of Oceanology Chinese Academy of SciencesGuangzhou 510301China

Nanoparticles are widely observed in the natural shear zone and experimental slip faults, which can lubricate the fault and significantly reduce the friction coefficient during seismic slip. But it is still not clear how the nanoparticles develop during the process of sliding. Clarifying the development stage of nanoparticles in a fault zone is critical to understanding the formation mechanisms of nanoparticles and the mechanism of fault weakening from a nanoperspective. In this study, four types of nanoparticles were found in the Indosinian Xiaomei shear zone, including spherical nanoparticles, rod-like nanograins and their aggregations. Ultramicroscopic analyses indicate that polished patches are highly smooth and composed of tightly packed spherical nanoparticles and well orientated rod-like nanograins during slip at high velocities. Meanwhile, the dome nanoparticles were formed by the calcite thermal decomposition due to frictional heat during highspeed sliding. The polygonal grooves are possibly related to high temperature(>900℃) grain boundary sliding deformation mechanisms. However, the porous and rough surfaces are accompanied by a series of holes and parallel "scratches" during a subsequent low-velocity stage. To ascertain the chemical composition of these nanoparticles, the energy dispersive spectrometer(EDS) test were conducted. The results suggest that materials rich in Fe, MgO and wollastonite are likely to form the rod-like nanograins, while materials rich in SiO2 are likely to form the spherical nanoparticles.

关键词： nanoparticles slip faults development stage Xiaomei shear zone composition

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Analysis of the CME-driven shock from the SEP event that occurred on 2006 December 14

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Research in Astronomy and Astrophysics 2012年第11期12卷 1535-1548页

作者： Xin Wang yi-Hua yan Key Laboratory of Solar Activities National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100012China State Key Laboratory of Space Weather Chinese Academy of SciencesBeijing 100080China

In a solar flare or coronal mass ejection （CME）, observations of the subse- quent interplanetary shock provide us with strong evidence of particle acceleration to energies of multiple MeV, even up to GeV. Diffusive shock acceleration is an efficient mechanism for particle acceleration. For investigating the shock structure, the energy injection and energy spectrum ofa CME-driven shock, we perform a dynamical Monte Carlo simulation of the CME-driven shock that occurred on 2006 December 14 using an anisotropic scattering law. The simulated results of the shock＇s fine structure, par- ticle injection, and energy spectrum are presented. We find that our simulation results give a good fit to the observations from multiple spacecraft.

关键词： acceleration of particles -- shock waves -- Sun: coronal mass ejections(CMEs) -- solar wind -- methods: numerical

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Innate immune responses to DNA viruses

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Protein & Cell 2013年第1期4卷 1-7页

作者： ying Nie yan-yi Wang Wuhan Institute of Virology Chinese Academy of SciencesWuhan 430071China Graduate University of Chinese Academy of Sciences Beijing 100049China

The innate immune system acts as the first line of defense against pathogens,which is also essen-tial for initiation of adaptive *** immune responses are initiated by pattern-recognition receptors(PRRs),which recognize conserved molecular structures of pathogens called patho-gen-associated molecular patterns(PAMPs).The infection of virus triggers a series of signaling events leading to transcriptional induction of type I interferons(IFNs)and proinflammatory *** recent years,the mechanisms of viral RNA recognition and RNA virus-triggered signaling pathways have been well ***,it remains unclear on how DNA virus infection is sensed by host cells and triggers the host antiviral *** ten potential viral DNA sen-sors have been reported,none of them is validated as a generally used sensor for distinct DNA viruses in divergent cell types and ***,we provide a summary and perspective on recent advances in innate immune responses to DNA viruses.

关键词： initiated nat pattern

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