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International Journal of Ophthalmology(English edition) 2025年第1期18卷 184-186页

作者： yi-Wen Xue yi-qin Xiao Department of Ophthalmology Huashan HospitalFudan UniversityShanghai 200040China

Dear Editor,We present a case of vitreous amyloidosis in a patient who was previously confirmed as familial amyloidosis polyneuropathy(FAP)because of peripheral neuropathy symptom *** though the patient had already undergone liver transplantation 5y prior,the extracellular deposition of amyloid in vitreous body greatly infected the patient’s visual function.

关键词： amyloid neuropathy function.

吡仑帕奈辅助治疗遗传性癫痫儿童的临床疗效及安全性研究

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中国当代儿科杂志 2025年第2期27卷 171-175页

作者：易珈沁孙丹华中科技大学同济医学院附属武汉儿童医院神经内科湖北武汉430016

目的分析吡仑帕奈(perampanel,PER)添加治疗遗传性癫痫患儿的疗效及安全性。方法回顾性分析2020年11月—2023年4月就诊于武汉儿童医院神经内科,给予PER添加治疗并经全外显子组测序确定为遗传性病因的53例癫痫患儿的临床资料。主要结局... 详细信息

目的分析吡仑帕奈(perampanel,PER)添加治疗遗传性癫痫患儿的疗效及安全性。方法回顾性分析2020年11月—2023年4月就诊于武汉儿童医院神经内科,给予PER添加治疗并经全外显子组测序确定为遗传性病因的53例癫痫患儿的临床资料。主要结局指标为PER治疗12个月时发作频率较基线减少≥50%的患儿比例(即有效率),次要结局指标为PER治疗3、6个月时的有效率。分析PER添加治疗遗传性癫痫疗效的影响因素,观察不良反应。结果中位随访时长13.10个月,随访12个月时共42例患儿纳入分析,男性25例(60%),女性17例(40%)。PER中位起始剂量为1.5(1.0,2.0)mg/d,中位维持剂量为4.0(3.0,8.0)mg/d。PER在治疗3、6、12个月有效率为61%(30/49)、54%(25/46)及48%(20/42),编码不同蛋白质功能的基因突变患儿的PER疗效比较差异无统计学意义(P>0.05)。最常见药物不良反应为疲乏(3例,6%)。结论PER添加治疗遗传性癫痫患儿有较好疗效及安全性,暂未发现影响PER疗效的相关因素。

关键词：癫痫吡仑帕奈添加治疗儿童

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煤矿井下自动钻机集控技术应用研究

矿山机械 2025年第1期53卷 11-15页

作者：秦怡煤矿灾害防控全国重点实验室重庆400039 中煤科工集团重庆研究院有限公司重庆400039

针对煤矿井下自动钻机单兵作战模式,提出“一站多控”方案,即一台远程交互控制站可控制多台自动钻机。采用现代数字信息处理、建模和通信技术,将同一区域的自动钻机联网,实现了钻机群的协同控制及管理。通过井下试验研究,结果表明:该方... 详细信息

针对煤矿井下自动钻机单兵作战模式,提出“一站多控”方案,即一台远程交互控制站可控制多台自动钻机。采用现代数字信息处理、建模和通信技术,将同一区域的自动钻机联网,实现了钻机群的协同控制及管理。通过井下试验研究,结果表明:该方案可以较大地减少钻机操作人员数量及管理成本,降低了钻进事故率及钻机故障率,提高了钻孔作业安全性,为煤矿安全智能化开采提供新技术。

关键词：自动钻机集控技术一站多控协同控制

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煤矿安全知识问答系统的答案生成模型研究

现代电子技术 2025年第2期48卷 61-69页

作者：于非凡董立红秦昳西安科技大学计算机科学与技术学院陕西西安710600

随着国家和煤矿行业对煤矿应急管理要求的逐步提高,对煤矿安全知识的学习也提出了更高的要求,因此建立一种煤矿安全知识智能问答模型。有效学习煤矿安全知识,对于确保煤矿企业工作人员的人身安全和预防煤矿安全事故的发生至关重要。首先... 详细信息

随着国家和煤矿行业对煤矿应急管理要求的逐步提高,对煤矿安全知识的学习也提出了更高的要求,因此建立一种煤矿安全知识智能问答模型。有效学习煤矿安全知识,对于确保煤矿企业工作人员的人身安全和预防煤矿安全事故的发生至关重要。首先,基于RoBERTa-wwm算法自动生成问答对数据,获取并分析煤矿安全知识原始文本数据,定义问题类型并标注问答对;然后,结合RoBERTa-wwm与UniLM,采用点互信息与邻接熵发现新词扩充领域词典,提出问答对自动生成算法,同时构建煤矿安全培训知识问答对数据集,解决煤矿安全知识系统问答对数据集问题;最后,引入问题相似度机制,针对无法回答问题和无关问题提出答案生成策略,构建基于问题相似度机制的答案生成模型,使其只关注可回答问题,从而提升模型的推理能力。实验结果表明,所提出的煤矿安全知识问答系统答案生成模型可有效识别无法回答和无关的问题,能够为煤矿企业工作人员提供知识支持,最大程度地提升煤矿企业工作人员安全培训学习效果。

关键词：智能问答系统煤矿安全答案生成 RoBERTa-wwm UniLM 点互信息邻接熵问题相似度

FAST IMPLEMENTATION OF ORTHOGONAL EMPIRICAL MODE DECOMPOSITION AND ITS APPLIGA-TION INTO HARMONIC DETECTION

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Chinese Journal of Mechanical Engineering 2008年第2期21卷 93-98页

作者： qin yi qin Shuren MAO Yongfang College of Mechanical Engineering Chongqing University Chongqing 400044 China

Since the empirical mode decomposition （EMD） lacks strict orthogonality, the method of orthogonal empirical mode decomposition （OEMD） is innovationally proposed. The primary thought of this method is to obtain the intrinsic mode function （IMF） and the residual function by auto-adaptive band-pass filtering. OEMD is proved to preserve strict orthogonality and completeness theoretically, and the orthogonal basis function of OEMD is generated, then an algorithm to implement OEMD fast, IMF binary searching algorithm is built based on the point that the analytical band-pass filtering preserves perfect band-pass feature in the frequency domain. The application into harmonic detection shows that OEMD successfully conquers mode aliasing, avoids the occurrence of false mode, and is featured by fast computing speed. Furthermore, it can achieve harmonic detection accurately combined with the least square method.

关键词： Empirical mode decomposition Orthogonal empirical mode decomposition Analytic band-pass filtering Binary searching Harmonic detection

Demodulation Based on Harmonic Wavelet and Its Application into Rotary Machinery Fault Diagnosis

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Chinese Journal of Mechanical Engineering 2009年第3期22卷 419-425页

作者： MAO Yongfang qin Shuren qin yi College of Automation Chongqing Univers#y Chongqing 400030 China

The harmonic wavelet transform（HWT） and its fast realization based on fast Fourier transform（FFT） are introduced. Its ability to maintain the same amplitude-frequency feature is revealed. A new method to construct the time-frequency（TF） spectrum of HWT is proposed, which makes the HWT TF spectrum able to correctly reflect the time-frequency-amplitude distribution of the signal. A new way to calculate the HWT coefficients is proposed. By zero padding the data taken out, the non-decimated coefficients of HWT are obtained. Theoretical analysis shows that the modulus of the coefficients obtained by the new calculation way and living at a certain scale are the envelope of the component in the corresponding frequency band. By taking the cross section of the new TF spectrum, the demodulation for the component at a certain frequency band can be realized. A comparison with the Hilbert demodulation combined with band-pass filtering is done, which indicates for multi-components, the method proposed here is more suitable since it realizes ideal band-pass filtering and avoids pass band selecting. In the end, it is applied to bearing and gearbox fault diagnosis, and the results reflect that it can effectively extract the fault features in the signal.

关键词： harmonic wavelet transform time-frequency spectrum demodulation rotary machinery fault diagnosis

From the Photochromic Metallacycles to the "Turn-On" Photo-Switchable Fluorescent Metallacycles

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Chinese Journal of Chemistry 2019年第5期37卷 531-532页

作者： yi qin Shanghai Key Laboratory of Green Chemistry and Chemical Processes School of Chemistry and Molecular Engineering East China Normal University 3663 North Zhongshan Road Shanghai 200062 China

Stimuli-responsive supramolecular self-assemblies have gained in creasing interests on acco unt of their exte nsive applicati ons in mimicking natural systems and materials science.[1-2] Our group has been interested in constructing diverse stimuli-responsive supramolecular assemblies and investigating their applications in sensing, catalysis and functional materials. As for the cleanest energy, light has always been chosen for the development of stimuli-responsive supramolecular self-assemblies.

关键词： materials group light

Gear Pitting Measurement by Multi-Scale Splicing Attention U-Net

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Chinese Journal of Mechanical Engineering 2023年第2期36卷 140-154页

作者： yi qin Dejun Xi Weiwei Chen yi Wang State Key Laboratory of Mechanical Transmission Chongqing UniversityChongqing 400044China College of Mechanical Engineering Chongqing UniversityChongqing 400044China

The judgment of gear failure is based on the pitting area ratio of *** gear pitting calculation method mainly rely on manual visual *** method is greatly affected by human factors,and is greatly affected by the working experience,training degree and fatigue degree of the detection personnel,so the detection results may be *** non-contact computer vision measurement can carry out non-destructive testing and monitoring under the working condition of the machine,and has high detection *** improve the measurement accuracy of gear pitting,a novel multi-scale splicing attention U-Net(MSSA U-Net)is explored in this *** image splicing module is first proposed for concatenating the output feature maps of multiple convolutional layers into a splicing feature map with more semantic ***,an attention module is applied to select the key features of the splicing feature *** that MSSA U-Net adequately uses multi-scale semantic features,it has better segmentation performance on irregular small objects than U-Net and attention *** the basis of the designed visual detection platform and MSSA U-Net,a methodology for measuring the area ratio of gear pitting is *** three datasets,experimental results show that MSSA U-Net is superior to existing typical image segmentation methods and can accurately segment different levels of pitting due to its strong segmentation ***,the proposed methodology can be effectively applied in measuring the pitting area ratio and determining the level of gear pitting.

关键词： Gear pitting Image segmentation Attention module Computer vision Quantitative detection

提示策略应用于学前孤独症儿童社会规则习得的案例研究

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盐城师范学院学报(人文社会科学版) 2025年第1期45卷 78-87页

作者：秦奕林晓雯南京特殊教育师范学院教育科学学院江苏南京210038 福建师范大学教育学院福建福州350104

社会规则习得对学前孤独症儿童适应性行为养成具有重要作用,成人发起且有计划实施的提示策略能够补偿障碍对儿童社会认知带来的不利影响。以孤独症儿童班级的三名康复教师为研究对象,聚焦儿童在园集体活动、区域游戏和个别化训练三种教... 详细信息

社会规则习得对学前孤独症儿童适应性行为养成具有重要作用,成人发起且有计划实施的提示策略能够补偿障碍对儿童社会认知带来的不利影响。以孤独症儿童班级的三名康复教师为研究对象,聚焦儿童在园集体活动、区域游戏和个别化训练三种教育情境,观察教师如何借助口语、视觉和动作三种提示策略帮助儿童习得社会规则,分析了提示策略的实施要点和背后的理论支持。建议重视基于个体差异实施不同提示策略,关注园本教研提升教师专业能力,强化家园协同促进社会规则学习迁移。

关键词：孤独症儿童规则习得社会适应提示策略

COUPLED ELECTRICAL-THERMAL-MECHANICAL ANALYSIS FOR ELECTRICAL/LASER HEATING ASSISTED BLANKING

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Chinese Journal of Mechanical Engineering 2006年第2期19卷 294-299页

作者： PENG Xianghe qin yi Department of Engineering Mechanics Chongqing UniversityChongqing 400044 China Department of Design Manufacture and Engineering ManagementUniversity of StrathclydeGlasgow G11XJ UK

A coupled electrical-thermal-mechanical analysis is conducted for electrical/laser heating assisted blanking. Two novel localized-heating methods, electrical heating and laser-heating, recently proposed for small-part blanking, are investigated with FE simulations. Results show that electrical heating would result in an advantageous distribution of temperature in a 316 stainless steel work-material. A desired temperature distribution may also be achievable for a copper work-material, if laser beam is used. Both electrical heating and laser-heating enable to reduce the blanking force and increase the aspect ratio achievable by blanking. The simulation also demonstrates that both electrical heating and laser-heating can result in desired temperature-distributions at sufficiently high heating-rates, ease of implementation and application. Comparatively, electrical heating could generate more favorable temperature distribution for small-part blanking.

关键词： Blanking Electrical heating Laser-heating