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Efficacy of Chinese herbal medicine for lumbar disc herniation: a systematic review of randomized controlled trials

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Journal of Traditional Chinese Medicine 2013年第6期33卷 721-726页

作者： yi luo Jian Huang Lin Xu Weikang Zhao Jie Hao Zhenming Hu Department of Orthopedic Surgery First Affiliated Hospital Chongqing Medical University Department of Traditional Chinese Medicine Chongqing Medical University Department of Orthopedics Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

OBJECTIVE: This is a review of the effects of Chinese herbal medicine(CHM) used alone to treat lumbar disc herniation(LDH). METHORDS: A literature search of the following electronic databases from their inception to February 2013 was conducted: Chinese Biomedical databases, Chinese National Knowledge Infrastructure, Wanfang Database, China Science and Technology Journal Database, Cochrane Library, Web of Science, MEDLINE, and EMBASE. Randomized controlled trials where CHM had been used to treat LDH were selected. Data extraction, quality assessment, and data analysis were carried out by two independent reviewers. RESULTS: Of the 2415 studies identified, eight with complete data on 1146 patients were selected. The methodological quality was poor in all trials. Five studies reported that CHM was better than Western Medicine [OR=2.81, 95% CI(1.27, 6.18); OR=3.34, 95% CI(1.92, 5.79); OR=2.22, 95% CI(1.08, 4.57); OR= 6.67, 95% CI(1.34, 33.28); and OR=1.94, 95% CI(1.23, 3.06)]. Two studies reported that the clinical outcome was better in CHM groups than in physiotherapy and placebo groups, [OR=3.02, 95% CI(1.08, 8.46); and OR=2.67, 95% CI(1.26, 5.64), respectively], whereas one study reported no difference between CHM and physiotherapy groups. One study reported that CHM resulted in higher Japanese Orthopedic Association scores [MD=7.78, 95% CI(6.67, 8.89)] than in a control group and another that participants treated with CHM had lower Visual Analogue Scale scores [MD=﹣0.72, 95% CI( ﹣0.86, ﹣0.58)] than those in a control group. Three studies reported that the adverse effects of CHM and Western Medicine did not differ significantly [OR=0.10, 95% CI(0.01, 1.85); OR=0.19, 95% CI(0.01, 4.07); and OR=0.07, 95% CI(0.00, 1.32)]. CONCLUSION: CHM may be more effective than other interventions for LDH; however, methodological weaknesses in the studies assessed in this review prevent a definitive conclusion. More high-quality large-scale studies are required to clarify this matter.

关键词：腰椎间盘突出症随机对照试验草药治疗中国疗效观察国家知识基础设施万方数据库中药治疗

Pannexin-1 infl uences peritoneal cavity cell population but is not involved in NLRP3 infl ammasome activation

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Protein & Cell 2013年第4期4卷 259-265页

作者： Hongbin Wang Yue Xing Liming Mao yi luo Lishan Kang Guangxun Meng Unit of Innate Immunity Key Laboratory of Molecular Virology and ImmunologyInstitut Pasteur of ShanghaiShanghai Institutes for Biological SciencesUniversity of Chinese Academy of SciencesShanghai 200025China Beijing Novo Nordisk Pharmaceuticals Science and Technology Co. Ltd.29 Life Science Park RoadBeijing 102206China

Pannexin-1(Panx1)forms nonselective large channel in cell plasma membrane and has been shown to be associated with NLRP3 inflammasome activation,ATP release and phagocytes recruitment.In the current study,by manipulation of Panx1 expression in human myeloid cells and application of Panx1 defi cient mice,we failed to fi nd a correlation between Panx1 and NLRP3 infl ammasome activation,although an interaction between these two proteins was evident.However,in thioglycollate induced peritonitis,Panx1 defi cient mice showed much more phagocytes infiltration.Further analyses showed that mice defi cient for Panx1 exhibited enlarged F4/80^(low)Gr1-Ly6C-cell population in the peritonea.Our study thus reveals an important role for Panx1 in regulation of peritoneal cell population and peritonitis development.

关键词： innate Immunity inflammasome NLRP3 Pannexin-1 peritonitis

Targeting gut microbiota in type 2 diabetes mellitus:Potential roles of dietary flavonoids

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Food Bioscience 2022年第1期45卷 8-19页

作者： Shuai Han yi luo Zuomin Hu Dandan Qin Feijun luo National Engineering Laboratory for Deep Process of Rice and Byproducts Hunan Key Laboratory of Grain-oil Deep Process and Quality ControlHunan Key Laboratory of Forestry Edible Resources Safety and ProcessingHunan Key Laboratory of Processed Food for Special Medical PurposeCentral South University of Forestry and TechnologyChangsha410004HunanChina Department of Clinic Medicine Xiangya School of MedicineCentral South UniversityChangsha410008HunanChina

Type 2 diabetes mellitus(T2DM)is a common endocrine and progressive metabolic disorder disease,which seriously threatens peoples’lives and health.Due to the high cost of clinical treatments and obvious side effects,looking for effective bioactive ingredients in the diet is an important strategy to prevent or even reduce the risk of diabetes.Epidemiological studies have suggested that dietary flavonoids have a potential antidiabetic effect,but the underlying mechanism remains unclear.Accumulating evidences indicates that gut microbiota has become an important target of dietary interventions.It plays essential roles in the digestion and absorption of flavonoids and affects the occurrence and progression of T2DM.This review systematically summarized the progress of dietary flavonoids targeting gut microbiota to ameliorate T2DM and analyzed possible molecular mechanisms.It suggests that flavonoids may prevent T2DM for healthy people and ameliorate health situations for T2DM patients.In addition,microbiota-based nutrition aims to provide personalized nutritional guidance to alter an individual’s microbiota and further improve response to dietary flavonoids,which will benefit to achieve a more effective diet for the prevention and management of T2DM.

关键词： Human health Type 2 diabetes mellitus(T2DM) Gut microbiota Dietary flavonoids Dietary recommendations

Massively parallel universal linear transformations using a wavelength-multiplexed diffractive optical network

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Advanced Photonics 2023年第1期5卷 27-49页

作者： Jingxi Li Tianyi Gan Bijie Bai yi luo Mona Jarrahi Aydogan Ozcan University of California Electrical and Computer Engineering DepartmentLos AngelesCaliforniaUnited States University of California Bioengineering DepartmentLos AngelesCaliforniaUnited States University of California California NanoSystems InstituteLos AngelesCaliforniaUnited States

Large-scale linear operations are the cornerstone for performing complex computational tasks.Using optical computing to perform linear transformations offers potential advantages in terms of speed,parallelism,and scalability.Previously,the design of successive spatially engineered diffractive surfaces forming an optical network was demonstrated to perform statistical inference and compute an arbitrary complex-valued linear transformation using narrowband illumination.We report deep-learning-based design of a massively parallel broadband diffractive neural network for all-optically performing a large group of arbitrarily selected,complex-valued linear transformations between an input and output field of view,each with Ni and No pixels,respectively.This broadband diffractive processor is composed of Nw wavelength channels,each of which is uniquely assigned to a distinct target transformation;a large set of arbitrarily selected linear transformations can be individually performed through the same diffractive network at different illumination wavelengths,either simultaneously or sequentially(wavelength scanning).We demonstrate that such a broadband diffractive network,regardless of its material dispersion,can successfully approximate Nw unique complex-valued linear transforms with a negligible error when the number of diffractive neurons(N)in its design is≥2NwNiNo.We further report that the spectral multiplexing capability can be increased by increasing N;our numerical analyses confirm these conclusions for Nw>180 and indicate that it can further increase to Nw∼2000,depending on the upper bound of the approximation error.Massively parallel,wavelength-multiplexed diffractive networks will be useful for designing highthroughput intelligent machine-vision systems and hyperspectral processors that can perform statistical inference and analyze objects/scenes with unique spectral properties.

关键词： optical neural network deep learning diffractive optical network wavelength multiplexing optical computing

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自组织网络下的无人机应急通信系统设计研究

通信电源技术 2024年第9期41卷 28-30页

作者：罗燚四川省德阳市消防救援支队四川德阳618000

在消防通信领域,自组织网络下无人机应急通信系统的设计关键在于解决稳定性、实时性与安全性问题。研究通过服务器数据库与消息交互设计,结合软硬件环境优化,专注于提升系统部署效率、视频传输稳定性及状态监控准确性。实现与测试环节... 详细信息

在消防通信领域,自组织网络下无人机应急通信系统的设计关键在于解决稳定性、实时性与安全性问题。研究通过服务器数据库与消息交互设计,结合软硬件环境优化,专注于提升系统部署效率、视频传输稳定性及状态监控准确性。实现与测试环节验证该设计的有效性,促进应急通信系统进一步优化技术集成与安全性,并提供应急通信新方案。

关键词：自组织网络无人机应急通信系统

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基于深度学习的观光车轴承故障诊断分析

模具制造 2024年第6期24卷 223-225页

作者：罗毅黔南州检验检测院贵州都匀558000

观光车作为城市观光、景区旅游的重要交通工具,其稳定性和可靠性对游客体验至关重要。轴承作为观光车的核心部件,其故障诊断对预防事故、保障安全具有重要意义。传统的轴承故障诊断方法主要依赖人工检测和经验判断,易受主观因素影响,且... 详细信息

观光车作为城市观光、景区旅游的重要交通工具,其稳定性和可靠性对游客体验至关重要。轴承作为观光车的核心部件,其故障诊断对预防事故、保障安全具有重要意义。传统的轴承故障诊断方法主要依赖人工检测和经验判断,易受主观因素影响,且难以实现实时监测。对此,需要探讨基于深度学习的观光车轴承故障诊断。

关键词：深度学习观光车轴承故障诊断

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贵州省长顺县摆所河河道治理方案研究

水科学与工程技术 2024年第1期 18-21页

作者：罗艺贵州省水利水电勘察设计研究院有限公司贵阳550001

贵州省长顺县摆所河尚未完成系统治理,近年洪水灾害频发,淹没农田时有发生,防洪形势不容忽视。通过对摆所河暴雨洪水分析,评价摆所镇河段河道行洪能力,根据河道地形、地质条件,研究比较不同堤型方案,提出最优治理工程措施,为今后防洪减... 详细信息

贵州省长顺县摆所河尚未完成系统治理,近年洪水灾害频发,淹没农田时有发生,防洪形势不容忽视。通过对摆所河暴雨洪水分析,评价摆所镇河段河道行洪能力,根据河道地形、地质条件,研究比较不同堤型方案,提出最优治理工程措施,为今后防洪减灾、河道治理等提供重要依据。

关键词：摆所河河道行洪能力治理方案

采煤机用变频器抗震装联工艺设计与振动试验研究

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煤炭技术 2024年第6期43卷 238-241页

作者：罗毅天地上海采掘装备科技有限公司上海201401

为提高采煤机用变频器的抗震性能,设计模块化电子装联工艺和分层检验标准,改进变频器组装工艺流程。为验证采煤机用变频器抗震装联效果,结合机载变频器使用工况条件制定振动试验原则,设计振动试验夹具与实施方案。这种研究方法适用于矿... 详细信息

为提高采煤机用变频器的抗震性能,设计模块化电子装联工艺和分层检验标准,改进变频器组装工艺流程。为验证采煤机用变频器抗震装联效果,结合机载变频器使用工况条件制定振动试验原则,设计振动试验夹具与实施方案。这种研究方法适用于矿用机载电气设备装联工艺验证试验设计,为提高机载电气设备抗震能力提供新的试验思路。

关键词：装联工艺变频器抗震性振动试验

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基于网络社交媒体的法语跨文化交往研究

文化创新比较研究 2024年第16期8卷 163-167页

作者：罗忆武昌工学院湖北武汉430065

该文旨在探讨网络社交媒体法语跨文化交往,并提出相应的促进策略。通过对塑造包容性网络环境、完善跨文化交流机制,以及加强法律法规和伦理规范等措施的分析,可以发现这些策略有助于促进跨文化交流。具体而言,多语言支持、文化分享、打... 详细信息

该文旨在探讨网络社交媒体法语跨文化交往,并提出相应的促进策略。通过对塑造包容性网络环境、完善跨文化交流机制,以及加强法律法规和伦理规范等措施的分析,可以发现这些策略有助于促进跨文化交流。具体而言,多语言支持、文化分享、打击歧视言论等举措,可建立开放、尊重的交流氛围;逐步完善跨文化交流机制、探索新的研究方法和技术,以及加强法律法规和伦理规范,可以深化对跨文化交流的理解,保障研究的合法性。该文认为通过采用这些策略,可以促进网络社交媒体法语跨文化交往的持续进行,推动跨文化交流的深入开展,提升法语跨文化交往的效果。

关键词：网络社交媒体法语跨文化交往策略语言