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The ethical dilemma of placebo use in clinical practice

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Frontiers of Nursing 2020年第3期7卷 203-208页

作者： chun-yi xu chun-Ming Yuan Department of Orthopedics Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalChengduSichuan 610000China

The clinical use of placebo that involves some ethical issues has led to much *** the standpoint of both supporters and opponents,this article discusses this topic from three ethical principles such as beneficence,justice,and autonomy and also gives the ***,the moral dilemma caused by the different views between nurses and doctors in clinical practice is discussed.

关键词： placebo ethical dilemma moral distress

Rehabilitation nursing for an earthquake survivor with severe polytrauma:A case report and literature review

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Journal of Integrative Nursing 2020年第3期2卷 149-152页

作者： chun‑yi xu Fang TANG Department of Orthopedic Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalChengduChina

The aim of this article is to summarize the experience of rehabilitation nursing of one case of severe polytrauma caused by *** key points of the rehabilitation nursing include body posture nursing,orthopedic rehabilitation nursing,pulmonary function rehabilitation nursing,bladder rehabilitation nursing,nutritional support,and psychological rehabilitation *** the comprehensive rehabilitation nursing interventions,satisfactory outcomes were obtained,and the patient was successfully recovered and discharged after 2 months.

关键词： Earthquake polytrauma rehabilitation nursing

Roles of MT-ND1 in Cancer

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Current Medical Science 2023年第5期43卷 869-878页

作者： yi-chun xu Jun SU Jia-jing ZHOU Qing YUAN Jun-song HAN Department of Pathology Shanghai Tongji HospitalTongji Hospital Affiliated to Tongji UniversityShanghai 200065China National Engineering Research Center for Biochip Shanghai Biochip Limited CorporationShanghai 201203China

The energy shift toward glycolysis is one of the hallmarks of *** I is a vital enzyme complex necessary for oxidative *** mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1(MT-ND1)is the largest subunit coded by mitochondria of complex *** present study summarizes the structure and biological function of *** databases and literature,the expressions and mutations of MT-ND1 in a variety of cancers have been ***-ND1 may be a biomarker for cancer diagnosis and *** is also a potential target for cancer therapy.

关键词： mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 cancer biomarker mutation

Isolating Ships from Shape Curve with DBSCAN

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Isolating Ships from Shape Curve with DBSCAN

Interaction of radiation-induced defects with tungsten grain boundaries at across scales: a short review

第25届中国控制与决策会议

作者： yi-chun xu Man Zhu Zunhai Ke Yong Liu Suifa Sun Computer and Information College China Three Gorges University

ISBN: (纸本)9781467355339

This paper proposes a video surveillance system to position ships in a ship lock. A background subtraction method is employed to extract the foreground of all ships. Subsequently, the DBSCAN clustering algorithm is applied to isolate each ship from the curves scanned from the extracted foreground regions. The system can locate adjacent ships and identify each one in real time. Theoretical analyses and ex periments show that the performance of the whole system depends on the quality of the foreground extraction. A robust backgrounds subtrac tion method can bring improved system performance.

关键词： Object Detection Image Segmentation Background Subtraction DBSCAN Video Surveillance

来源： cnki会议评论

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Tungsten 2020年第1期2卷 15-33页

作者： Xiang‑Yan Li Yan‑Ge Zhang yi‑chun xu xue‑Bang Wu Xiang‑Shan Kong Xian‑Ping Wang Qian‑Feng Fang Chang‑Song Liu Key Laboratory of Materials Physics Institute of Solid State PhysicsChinese Academy of SciencesHefei 230031China Key Laboratory for Liquid‑Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJinan 250061China

As promising candidates for plasma-facing materials,tungsten-based materials suffer the irradiation of high-energy neutrons in addition to the hydrogen isotopes and helium irradiation and the high-thermal ***-produced defects,***-interstitial atoms(SIAs)and vacancies(Vs),can induce the hardening and embrittlement of tungsten,meanwhile enhancing the retention of hydrogen isotopes and helium in *** the grain size of materials to introduce a high density of defect sinks,e.g.,grain boundaries(GBs)prevalent in nano-/ultrafine-crystalline materials,was demonstrated to be an effective approach for mitigating irradiation damage in *** this paper,we reviewed the theoretical advances in exploring radiation-resistance of nano-structured tungsten at across *** was concentrated on the results of molecular dynamics,molecular statics,and the object kinetic Monte Carlo simulations on the fundamental interaction of the radiation-created Vs and SIAs with the *** mechanisms include GB-promoted V/SIA migration and SIA-V recombination,interstitial-emission induced annihilation,coupling of the V migration close to the GB with the SIA motion within the GB,and interstitial reflection by the locally dense GB *** proposed the remaining scientific issues on the defect-GB interactions at across scales and their relation to experimental *** prospected the possible trends for simulating the radiation damage accumulation and healing processes in nano-structured tungsten in terms of the development of the across-scale computational techniques and efficiency of the GB-enhanced tolerance of tungsten to irradiation under complex in-service conditions.

关键词： Nano-crystalline Grain boundary Radiation-resistance Self-healing Radiation damage Tungsten

A deep learning interatomic potential suitable for simulating radiation damage in bulk tungsten

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Tungsten 2024年第2期6卷 304-322页

作者： Chang-Jie Ding Ya-Wei Lei Xiao-Yang Wang Xiao-Lin Li Xiang-Yan Li Yan-Ge Zhang yi-chun xu Chang-Song Liu xue-Bang Wu Key Laboratory of Materials Physics Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China Science Island University of Science and Technology of ChinaHefei 230026China Laboratory of Computational Physics Institute of Applied Physics and Computational MathematicsBeijing 100088China

So far, it has been a challenge for existing interatomic potentials to accurately describe a wide range of physical properties and maintain reasonable efficiency. In this work, we develop an interatomic potential for simulating radiation damage in body-centered cubic tungsten by employing deep potential, a neural network-based deep learning model for representing the potential energy surface. The resulting potential predicts a variety of physical properties consistent with first-principles calculations, including phonon spectrum, thermal expansion, generalized stacking fault energies, energetics of free surfaces, point defects, vacancy clusters, and prismatic dislocation loops. Specifically, we investigated the elasticity-related properties of prismatic dislocation loops, i.e., their dipole tensors, relaxation volumes, and elastic interaction energies. This potential is found to predict the maximal elastic interaction energy between two 1/2 loops better than previous potentials, with a relative error of only 7.6%. The predicted threshold displacement energies are in reasonable agreement with experimental results, with an average of 128 eV. The efficiency of the present potential is also comparable to the tabulated gaussian approximation potentials and modified embedded atom method potentials, meanwhile, can be further accelerated by graphical processing units. Extensive benchmark tests indicate that this potential has a relatively good balance between accuracy, transferability, and efficiency.

关键词： Machine learning Deep learning Interatomic potential Radiation damage Tungsten

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基于拉曼光谱的复杂硫化矿快速分类方法研究

光谱学与光谱分析 2017年第1期37卷 129-134页

作者：蔡耀仪阳春华徐德刚李原鹰桂卫华中南大学信息科学与工程学院湖南长沙410083 湖南师范大学工程与设计学院湖南长沙410083

热液硫化物型脉状矿作为一类复杂硫化矿,其区域特征、成矿规律及矿物成份已有初步研究。由于成矿时期的不同,矿石中有用矿物的特征存在较大差异,导致不同矿物的性质变化较大。在选矿过程中,矿物性质的差异一定程度增加了选矿难度,减少... 详细信息

热液硫化物型脉状矿作为一类复杂硫化矿,其区域特征、成矿规律及矿物成份已有初步研究。由于成矿时期的不同,矿石中有用矿物的特征存在较大差异,导致不同矿物的性质变化较大。在选矿过程中,矿物性质的差异一定程度增加了选矿难度,减少了有用矿物回收率。因此,迫切需要一种快速、简单的对复杂硫化矿进行分类的方法,进而提高选矿指标。激光拉曼光谱技术作为一种能够分析物质结构信息的手段,已被应用于矿物的成份鉴定和结构分析。通过对大量矿物样本的激光拉曼光谱的研究,结合矿物性质深入揭示其光谱差异的原因,提出了一种基于拉曼光谱的复杂硫化矿矿源分类方法。实验结果表明:由于此类复杂硫化矿成矿时期的差异,从而造成矿物结构和性质存在较大差异。荧光主要由原矿中的脉石矿物产生,猝灭矿物中瞒石的荧光背景后可知201.62,242.54,288.38和309.77cm-1处拉曼峰可以作为此类硫化矿的拉曼指纹谱。为此,基于此类硫化矿的荧光强度和代表谱峰强度与荧光背景比值可以将矿源分为三类,并利用工业试验结果进一步验证分类方法的准确性。本研究深入分析了此类复杂硫化矿的激光拉曼光谱与其矿物性质与类别之间的密切关系,提出了矿源快速分类方法,矿样无需经过复杂的化学前处理过程,对提高选矿作业效率具有重要应用价值。

关键词：拉曼光谱硫化矿荧光散射成矿时期分类

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乡道公路改造中梁桥加固、拓宽方法的研究

交通标准化 2007年第1期35卷 141-143页

作者：伊旭春浙江省台州市公路管理处浙江台州318000

根据乡道公路改造过程中中小跨径梁桥的主要病害,结合乡道改造资金不足等实际情况,借鉴工程经验和专业处置措施,分别提出相应的修补桥台、拓宽桥面、重新铺装等经济、有效的技术方案,可供乡道公路梁桥改造参考。

关键词：梁桥病害加固拓宽重新铺装

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis

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Neural Regeneration Research 2025年第2期20卷 354-365页

作者： Li xu Huiming xu Changyong Tang Department of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor *** date,no effective treatment exists as the exact causative mechanism remains ***,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic *** most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets *** experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum *** this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model *** addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.

关键词： aquaporin-4 experimental model neuromyelitis optica spectrum disorder pathogenesis