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CYBERNETIC PARADIGM BASED INNOVATIVE APPROACHES TOWARDS COPING WITH CLIMATE CHANGE

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Journal of Systems Science and Systems Engineering 2017年第3期26卷 359-382页

作者： yi lu Jiuping Xu Uncertainty Decision-making Laboratory Sichuan University Chengdu 610064 China Engineering Research Center of Low Carbon Technology and Economy Sichuan University Chengdu 610064 China

Increasing carbon emissions from large-scale human activities have contributed to global climate change, which has resulted in an increase in significant human crises. Therefore, as carbon abatement is a public good, coping with climate change is also a public-good; however, it suffers from many free-rider incentives, leading to a tragedy of the commons. Overcoming this challenge from a systemic perspective, requires that all sectors such as industry, government, and citizens on global, national, and regional levels engage in low-carbon development and the implementation of fair and efficient climate policies. Through a theoretical exploration of carbon abatement and a systemic description of low-carbon systems, this paper developed a cybernetic framework for coping with climate change, which consists of a cloud platform for data analysis, meta-synthetic engineering for decision support, a polycentric approach to extensive consultation and various functional goal achievement modules. On this basis, by combining the ＂invisible hand＂ and ＂visible hand＂ and by integrating negotiation at the global level, cooperation at the national level and knowledge at the local level, a multilevel policymaking model is proposed to address complex climate change problems. This cybernetic paradigm based innovative approach could provide valuable illumination to stakeholders seeking to cope with climate change.

关键词： Cybernetics climate change carbon abatement public good low-carbon development

Kinetostatics Analysis of a Novel 6-DOF Parallel Manipulator with Three Planar Limbs and Equipped with Three Fingers

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Chinese Journal of Mechanical Engineering 2014年第5期27卷 919-927页

作者： lu yi LI Xuepeng College of Mechanical Engineering Yanshan University Key Laboratory of Parallel Robot and Mechatronic System of Hebei Province Key Laboratory of Advanced Forging & Stamping Technology and Science of Ministry of National Education

It is significant to develop a robot hand with high rigidity by a 6-DOF parallel manipulator（PM）.However,the existing6-DOF PMs include spherical joint which has less capability of pulling force bearing,less rotation range and lower precision under alternately heavy loads.A novel 6-DOF PM with three planar limbs and equipped with three fingers is proposed and its kinematics and statics are analyzed systematically.A 3-dimension simulation mechanism of the proposed manipulator is constructed and its structure characteristics is *** kinematics formulae for solving the displacement,velocity,acceleration of the platform,the active legs and the fingers are *** statics formulae are derived for solving the active forces of PM and the finger *** analytic example is given for solving the kinematics and statics of proposed manipulator and the analytic solved results are verified by the simulation *** is proved from the error analysis of analytic solutions and simulation solutions that the derived analytic formulae are correct and provide the theoretical and technical foundations for its manufacturing,control and application.

关键词： parallel manipulator planar limbs finger kinematics statics

An experimental setup with controllable tuning parameters for studying the Kondo systems

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Science China(Physics,Mechanics & Astronomy) 2022年第4期65卷 121-122页

作者： Zhong-yi lu Department of Physics Renmin University of ChinaBeijing 100872China

The Kondo physics has been studied since the 1960 s in condensed matter physics[1,2],which is mainly determined by two competing factors namely the Kondo effect and the Ruderman-Kittel-Kasuya-Yosida(RKKY)interaction.

关键词： interaction Kondo condensed

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The role of oxygen vacancies in metal oxides for rechargeable ion batteries

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Science China Chemistry 2021年第11期64卷 1826-1853页

作者： Runzhe Wei yi lu Yang Xu Department of Chemistry University College LondonLondonWC1H 0AJUK

Rechargeable ion batteries are one of the most reliable energy storage technologies for the applications ranging from small portable devices and electric vehicles to renewable energy integration and large-scale stationary energy *** the roadmap of developing and understanding new electrode materials for rechargeable ion batteries,oxygen vacancies,known as defects in metal oxides,have shown a high impact on the final electrochemical performance of the *** present review aims to summarise the synthesis methods and characterisation techniques of oxygen vacancies as well as some of the most recent and exciting progress made to understand the role of oxygen vacancies in the electrochemical performance of Li-,Na-,K-and Zn-ion *** review discusses not only the role of oxygen vacancies directly in electrode materials and indirectly in the coating layers on electrode materials,but also the synergistic role of oxygen vacancies interplaying with other contributors such as carbonaceous materials,doping,amorphisation,structural transformation,nanostructuring and functional ***,perspectives are given to stimulate new ideas and open questions to facilitate the further development of oxygen deficient electrode materials in energy research landscape.

关键词： oxygen vacancies defect chemistry metal oxide rechargeable ion batteries ion diffusion intercalation reaction conversion reaction

Pseudovirus-based neuraminidase inhibition assays reveal potential H5N1 drug-resistant mutations

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Protein & Cell 2013年第5期4卷 356-363页

作者： yi lu Taijiao Jiang Key Laboratory of Protein and Peptide Pharmaceuticals National Laboratory of BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China College of Life Sciences University of Chinese Academy of SciencesBeijing 100049China

The use of antiviral drugs such as influenza neuraminidase (NA) inhibitors is a critical strategy to prevent and control flu pandemic, but this strategy faces the challenge of emerging drug-resistant strains. For a highly pathogenic avian influenza (HPAI) H5N1 virus, biosafety restrictions have significantly limited the efforts to monitor its drug responses and mechanisms involved. In this study, a rapid and biosafe assay based on NA pseudovirus was developed to study the resistance of HPAI H5N1 virus to NA inhibitor drugs. The H5N1 NA pseudovirus was comprehensively tested using oseltamivir-sensitive strains and their resistant mutants. Results were consistent with those in previous studies, in which live H5N1 viruses were used. Several oseltamivir-resistant mutations reported in human H1N1 were also identified to cause decreased oseltamivir sensitivity in H5N1 NA by using the H5N1 NA pseudovirus. Thus, H5N1 NA pseudoviruses could be used to monitor HPAI H5N1 drug resistance rapidly and safely.

关键词： infl uenza virus H5N1 neuraminidase inhibi-tor drug resistance pseudovirus

SYMPLECTIC SCHEMES FOR TELEGRAPH EQUATIONS

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Journal of Computational Mathematics 2016年第3期34卷 285-299页

作者： yi lu Yaolin Jiang School of Mathematics and Statistics Xi'an Jiaotong University Shaanxi 710049 China

A new numerical algorithm for telegraph equations with homogeneous boundary con- ditions is proposed. Due to the damping terms in telegraph equations, there is no royal conservation law according to Noether＇s theorem. The algorithm origins from the discovery of a transform applied to a telegraph equation, which transforms the telegraph equation to a Klein-Gordon equation. The Symplectic method is then brought in this algorithm to solve the Klein-Gordon equation, which is based on the fact that the Klein-Gordon equation with the homogeneous boundary condition is a perfect Hamiltonian system and the symplectic method works very well for Hamiltonian systems. The transformation itself and the inverse transformation theoretically bring no error to the numerical computation. Therefore the error only comes from the symplectic scheme chosen. The telegraph equation is finally explicitly computed when an explicit symplectic scheme is utilized. A relatively long time result can be expected due to the application of the symplectic method. Mean- while, we present order analysis for both one-dimensional and multi-dimensional cases in the paper. The efficiency of this approach is demonstrated with numerical examples.

关键词： Telegraph equation Klein-Gordon equation Symplectic method Explicitmethod.

Recent advances in DNAzyme-based gene silencing

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Science China Chemistry 2017年第5期60卷 591-601页

作者： Huanhuan Fan Xiaobing Zhang yi lu Molecular Science and Biomedicine Laboratory State Key Laboratory of Chemo/Bio-Sensing and Chemometrics Collaborative Innovation Center for Chemistry and Molecular MedicineCollege of Chemistry and Chemical Engineering College of Biology Hunan University Changsha 410082 China Department of Chemistry Materials Science and Engineering University of Illinois at Urbana-Champaign Urbana Illinois 61801 USA

DNAzymes, generated through in vitro selection processes, are single-stranded DNA catalysts that can catalyze a wide variety of reactions, such as RNA or DNA cleavage and ligation or DNA phosphorylation. Based on specific cofactor dependence and potent catalytic ability, DNAzymes have been extensively used to develop highly sensitive and specific sensing platforms for metal ions,small molecules, and biomacromolecules. However, in spite of their multiple strong enzymatic turnover properties, few reports have addressed the potential application of RNA-cleaving DNAzymes as therapeutic gene-silencing agents. The main challenges are being met with low efficiency of cellular uptake, instability and the lack of sufficient cofactors for cellular or in vivo study, which have limited the development of DNAzymes for clinical application. In recent years, substantial progress has been made to enhance the delivery efficiency and stability of DNAzymes by developing variety of methods. Smart metal oxide nanomaterials have also been used to meet the requirement of cofactors in situ. This review focuses on the gene silencing application of DNAzymes as well as their physicochemical properties. Methods of increasing the efficacy of DNAzymes in gene therapy are also discussed: delivery systems to enhance the cellular uptake, modifications to enhance the stability and smart systems to generate sufficient cofactors in situ. Finally, some future trends and perspectives in these research areas are outlined.

关键词： DNAzymes gene-silencing delivery stability cofactors

Efficient photoelectrodes based on two-dimensional transition metal dichalcogenides heterostructures:from design to construction

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Rare Metals 2022年第4期41卷 1142-1159页

作者： Xiang-Chao lu yi-Zhen lu Cong Wang Yang Cao State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials(iChEM)College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China

Hydrogen production by photoelectrochemical(PEC) water splitting converts the inexhaustible supply of solar radiation to storable H2 as clean energy and thus has received widespread *** efficiency of PEC water splitting is largely determined by the properties of the ***-dimensional(2 D) layered transition metal dichalcogenides(TMDs) are promising candidates for photoelectrodes due to their atomic layer thickness,tunable bandgap,large specific surface area,and high carrier ***,the construction of 2 D TMDs heterostructures provides freedom in material design,which facilitates the further improvement of PEC water *** review begins by describing the mechanism of PEC water splitting and the advantages of 2 D TMDbased heterostructures for photo ***,the design considerations of the heterostructures for enhanced PEC efficiency are comprehensively reviewed with a focus on material selection,band engineering,surface modification,and long-term ***,current challenges and future perspectives for the development of photoelectrodes based on 2 D TMDs heterostructures are addressed.

关键词： Two-dimensional transition metal van der Waals heterostructure Photoelectrode Photoelectrochemical cell Water splitting

A Hazard Analysis-based Approach to Improve the Landing Safety of a BWB Remotely Piloted Vehicle

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Chinese Journal of Aeronautics 2012年第6期25卷 846-853页

作者： lu yi ZHANG Shuguang LI Xueqing Airworthiness Technologies Research Center Beihang University Beijing 100191 China

The BUAA-BWB remotely piloted vehicle （RPV） designed by our research team encountered an unexpected landing safety problem in flight tests. It has obviously affected further research project for blended-wing-body （BWB） aircraft configuration characteristics. Searching for a safety improvement is an urgent requirement in the development work of the RPV. In view of the vehicle characteristics, a new systemic method called system-theoretic process analysis （STPA） has been tentatively applied to the hazardous factor analysis of the RPV flight test. An uncontrolled system behavior ＂path sagging phenomenon＂ is identified by implementing a three degrees of freedom simulation based on wind tunnel test data and establishing landing safety system dynamics archetype. To obtain higher safety design effectiveness and considering safety design precedence, a longitudinal ＂belly-flap＂ control surface is innovatively introduced and designed to eliminate hazards in landing. Finally, flight tests show that the unsafe factor has been correctly identified and the landing safety has been efficiently improved.

关键词： BWB RPV landing safety STPA system dynamics safety design precedence sagging phenomenon belly-flap