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Can the Bass innovation diffusion model describe adsorption breakthrough curves of pharmaceutical contaminants?

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Green Chemical Engineering 2024年第2期5卷 145-149页

作者： Khim Hoong chu Mohd Ali Hashim Department of Chemical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur50603Malaysia

*** Fixed bed adsorption is a widely used separation process in the chemical industry for the processing of liquids and *** performance of fixed bed adsorption systems is often evaluated by analyzing the breakthrough curves,which represent the variation of the solute concentration in the effluent stream as a function of time or bed volume.

关键词： adsorption breakthrough curves

Strigolactone regulates nitrogen-phosphorus balance in rice

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Science China(Life Sciences) 2024年第2期67卷 428-430页

作者： Huwei Sun Hanyun Wang Chengcai chu Guangdong Provincial Key Laboratory of Plant Molecular Breeding College of AgricultureSouth China Agricultural UniversityGuangzhou 510642China Key Laboratory for Enhancing Resource Use Efficiency of Crops in South China Ministry of Agriculture and Rural AffairsSouth China Agricultural UniversityGuangzhou 510642China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642

Phosphorus(P) is one of the essential elements for growth and development of *** agriculture depends heavily on the application of large amounts of fertilizers,including P *** application of P fertilizers causes sever... 详细信息

关键词： pollution phosphorus fertilizers

Navigating Epstein–Barr virus autoimmunity:role of NK cells and T cells in multiple sclerosis

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Signal Transduction and Targeted Therapy 2024年第3期9卷 833-835页

作者： chu Xie Cong Sun Mu-Sheng Zeng State Key Laboratory of Oncology in South China Guangdong Provincial Clinical Research Center for CancerGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer CenterGuangzhouP.R.China

In a recent study published in Cell,Vietzen and colleagues discovered the novel role of natural killer(NK)cells and EBVspecific CD8+T cell response in controlling EBV-inducing autoimmune response and collectively def... 详细信息

关键词： Epstein sclerosis killer

Structural characterization of three acidic polysaccharides from Opuntia dillenii *** and their protective effect against hydrogen peroxide-induced oxidative stress in Huh-7 cells

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Food Science and Human Wellness 2024年第4期13卷 1929-1942页

作者： Rui Liu Fangxin chu Zheng Yan Hanqing Chen School of Food and Biological Engineering Hefei University of TechnologyHefei 230601China Engineering Research Center of Bio-Process Ministry of EducationHefei University of TechnologyHefei 230601China

Three novel acidic polysaccharide fractions(OFPP-1,OFPP-2,OFPP-3)with different m olecular weights(803.7,555.1 and 414.5 k Da)were isolated from the peeled Opuntia dillenii *** by alkali-extraction,graded alcohol precipitation and column *** analysis indicated that OFPPs were pectic polysaccharides consisting of rhamnose,arabinose and galactose *** backbone of OFPP-1 consisted of a repeating unit→6-α-D-Galp A-(1→2)-α-L-Rhap-(1→with T-α-D-Galp A-(1→6)-α-D-Galp A-(1→4)-α-D-Glcp-(1→,T-β-D-Xylp-(1→6)-α-D-Galp A-(1→4)-α-D-Glcp-(1→or T-α-D-Galp A-(1→3)-α-L-Araf-(1→as the side *** backbone of OFPP-2 consisted of a disaccharide repeating unit→2)-α-L-Rhap-(1→4)-β-D-Galp A-(1→with T-β-L-Araf-(1→as the branches substituted at the O-4 position of→2,4)-α-LRhap-(1→.Whereas the backbone of OFPP-3 was→2,4)-α-L-Rhap-(1→2)-α-L-Rhap-(1→3)-β-L-Araf-(1→or→2,4)-α-L-Rhap-(1→2)-α-L-Rhap-(1→4)-β-D-Galp A-(1→,which was branched at the O-4 position of→2,4)-α-L-Rhap-(1→.Moreover,these three polysaccharide fractions could protect Huh-7 cells against H2O2-induced oxidative stress to different extents by decreasing the MDA content and increasing the SOD,CAT,GSH-Px activities and the GSH level in the Huh-7 *** results suggest that OFPPs have the potential to be used as natural antioxidants.

关键词： Opuntia dillenii Haw.fruits Polysaccharide Alkali extraction Structural characterization Oxidative stress

MOF-derived porous graphitic carbon with optimized plateau capacity and rate capability for high performance lithium-ion capacitors

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International Journal of Minerals,Metallurgy and Materials 2024年第2期31卷 395-404页

作者： Ge chu Chaohui Wang Zhewei Yang Lin Qin Xin Fan College of Materials Science&Engineering Guilin University of TechnologyGuilin 541004China Institute of Energy Innovation College of Materials Science and EngineeringTaiyuan University of TechnologyTaiyuan 030024China

The development of anode materials with high rate capability and long charge-discharge plateau is the key to improve per-formance of lithium-ion capacitors(LICs).Herein,the porous graphitic carbon(PGC-1300)derived from a new triply interpenetrated co-balt metal-organic framework(Co-MOF)was prepared through the facile and robust carbonization at 1300°C and washing by HCl *** as-prepared PGC-1300 featured an optimized graphitization degree and porous framework,which not only contributes to high plateau capacity(105.0 mAh·g^(−1)below 0.2 V at 0.05 A·g^(−1)),but also supplies more convenient pathways for ions and increases the rate capability(128.5 mAh·g^(−1)at 3.2 A·g^(−1)).According to the kinetics analyses,it can be found that diffusion regulated surface induced capa-citive process and Li-ions intercalation process are coexisted for lithium-ion ***,LIC PGC-1300//AC constructed with pre-lithiated PGC-1300 anode and activated carbon(AC)cathode exhibited an increased energy density of 102.8 Wh·kg^(−1),a power dens-ity of 6017.1 W·kg^(−1),together with the excellent cyclic stability(91.6%retention after 10000 cycles at 1.0 A·g^(−1)).

关键词： metal-organic framework porous graphitic carbon optimized plateau capacity kinetic analysis lithium-ion capacitor

Finite Element Simulations on Failure Behaviors of Granular Materials with Microstructures Using a Micromechanics-Based Cosserat Elastoplastic Model

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Computer Modeling in Engineering & Sciences 2024年第3期138卷 2305-2338页

作者： Chenxi Xiu Xihua chu School of Civil Engineering Chongqing Jiaotong UniversityChongqing400074China School of Civil Engineering Wuhan UniversityWuhan430072China

This paper presents a micromechanics-based Cosserat continuum model for microstructured granular *** utilizing this model,the macroscopic constitutive parameters of granular materials with different microstructures are expressed as sums of microstructural *** microstructures under consideration can be classified into three categories:a medium-dense microstructure,a dense microstructure consisting of one-sized particles,and a dense microstructure consisting of two-sized ***,the Cosserat elastoplastic model,along with its finite element formulation,is derived using the extended Drucker-Prager yield *** investigate failure behaviors,numerical simulations of granular materials with different microstructures are conducted using the ABAQUS User Element(UEL)*** demonstrates the capacity of the proposed model to simulate the phenomena of strain-softening and strain *** study investigates the influence of microscopic parameters,including contact stiffness parameters and characteristic length,on the failure behaviors of granularmaterials ***,the study examines themesh independence of the presented model and establishes its relationship with the characteristic length.A comparison is made between finite element simulations and discrete element simulations for a medium-dense microstructure,revealing a good agreement in results during the elastic *** parameters describing plasticity are shown to be partially related to microscopic factors such as confining pressure and size of the representative volume element.

关键词： Granular materials micromechanics Cosserat elastoplastic model microstructures failure behaviors

Intuitive Human-Robot-Environment Interaction With EMG Signals:A Review

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1075-1091页

作者： Dezhen Xiong Daohui Zhang Yaqi chu Yiwen Zhao Xingang Zhao State Key Laboratory of Robotics Shenyang Institute of AutomationChinese Academy of SciencesShenyang 110016 Institutes for Robotics and Intelligent Manufacturing Chinese Academy of SciencesShenyang 110169 University of Chinese Academy of Sciences Beijing 100049China

A long history has passed since electromyography(EMG)signals have been explored in human-centered robots for intuitive ***,it still has a gap between scientific research and real-life *** studies mainly focused on EMG decoding algorithms,leaving a dynamic relationship between the human,robot,and uncertain environment in real-life scenarios seldomly *** fill this gap,this paper presents a comprehensive review of EMG-based techniques in human-robot-environment interaction(HREI)*** general processing framework is summarized,and three interaction paradigms,including direct control,sensory feedback,and partial autonomous control,are ***-based intention decoding is treated as a module of the proposed *** key issues involving precision,stability,user attention,compliance,and environmental awareness in this field are *** important directions,including EMG decomposition,robust algorithms,HREI dataset,proprioception feedback,reinforcement learning,and embodied intelligence,are proposed to pave the way for future *** the best of what we know,this is the first time that a review of EMG-based methods in the HREI system is *** provides a novel and broader perspective to improve the practicability of current myoelectric interaction systems,in which factors in human-robot interaction,robot-environment interaction,and state perception by human sensations are considered,which has never been done by previous studies.

关键词： robot summarized Robot

Developing risk models and subtypes of autophagy-associated LncRNAs for enhanced prognostic prediction and precision in therapeutic approaches for liver cancer patients

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Oncology Research 2024年第4期32卷 703-716页

作者： LU ZHANG JINGUO chu YUSHAN YU Department of General Practice The First Affiliated Hospital of Ningbo UniversityNingboChina

Background:Limited research has been conducted on the influence of autophagy-associated long non-coding RNAs(ARLncRNAs)on the prognosis of hepatocellular carcinoma(HCC).Methods:We analyzed 371 HCC samples from TCGA,identifying expression networks of ARLncRNAs using autophagy-related *** for prognostically relevant ARLncRNAs involved univariate Cox regression,Lasso regression,and multivariate Cox regression.A Nomogram was further employed to assess the reliability of Riskscore,calculated from the signatures of screened ARLncRNAs,in predicting ***,we compared drug sensitivities in patient groups with differing risk levels and investigated potential biological pathways through enrichment analysis,using consensus clustering to identify subgroups related to ***:The screening process identified 27 ARLncRNAs,with 13 being associated with HCC ***,a set of signatures comprising 8 ARLncRNAs was successfully constructed as independent prognostic factors for *** in the high-risk group showed very poor prognoses in most clinical *** Riskscore was closely related to immune cell scores,such as macrophages,and the DEGs between different groups were implicated in metabolism,cell cycle,and mitotic ***,high-risk group patients demonstrated a significantly lower IC50 for Paclitaxel,suggesting that Paclitaxel could be an ideal treatment for those at elevated risk for *** further identified C2 as the Paclitaxel subtype,where patients exhibited higher Riskscores,reduced survival rates,and more severe clinical ***:The 8 signatures based on ARLncRNAs present novel targets for prognostic prediction in *** drug candidate Paclitaxel may effectively treat HCC by impacting ARLncRNAs *** the identification of ARLncRNAsrelated isoforms,these results provide valuable insights for clinical exploration of autophagy mechanisms in HCC pathogenesis and offer potential av

关键词： Autophagy Hepatocellular carcinoma(HCC) Prognosis Precision medicine Paclitaxel

Enzyme-driven Nanorobots Walking Along Predesigned Tracks on the DNA Origami for Cargo Transport and Catalysis

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Chemical Research in Chinese Universities 2024年第2期40卷 333-342页

作者： NIE Cunpeng MA Tianran CHEN Tingting chu Xia State Key Laboratory of Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha410082P.R.China

In molecular engineering,designing and synthesizing molecular machines with capable of performing complex tasks,remains a formidable *** is an excellent candidate for building molecular robots because it is highly ***,we present an artificial nanorobot,in which a DNA cube serves as the inert‘body’,and nucleic acid catalysts based on an enzymatic nicking reaction act as the‘legs’for *** nanorobot can execute a series of actions,such as‘start’,‘turn’,and‘stop’when it walks along a predefined *** performance could be confirmed and monitored by using an atomic force microscope(AFM)and fluorescence *** by biological machines,we artificially designed a series of specialized tasks that combined walking with control of cargo transport and ***-time fluorescence kinetics curves provide monitoring signals for cargo transport and catalytic *** work can enrich the toolbox of DNA machinery and has great potential for engineering molecular nanofactories.

关键词： DNA origami DNA nanorobot Controlled cargo transport DNAzyme catalysis