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Open Journal of Obstetrics and Gynecology 2018年第3期8卷 170-174页

作者： Divyesh V. Shukla Shilpi D. Shukla Ajay Valia yesha chokshi Isha Hospital Sarabhai Campus Vadodara India

This case is of Rh -ve 2nd gravida having antibody titre detected 1:2 at 8 weeks of 2nd pregnancy. Serial antibody titre carried out along with clinical examination. Fetal monitoring was done by assessing MCA-PSV (Middle cerebral artery peak systolic velocity) and CTG (Cardiotocograph) when required. Pregnancy was terminated when the titre reached 1:512 at 34 wks of pregnancy with abnormal MCA-PSV values. Neonate just had begun to show sign of anaemia & haemolysis at birth.

关键词： Rh -Ve Rh +Ve MCA-PSV CTG Rh Isoimmunization Rh Antibody Titre

Advances in teleophthalmology and artificial intelligence for diabetic retinopathy screening:a narrative review

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Annals of Eye Science 2024年第2期9卷 24-37页

作者： Tanvi chokshi Maria Jessica Cruz Jonathon Ross Glenn Yiu Tschannen Eye Institute Department of OphthalmologyUniversity of CaliforniaDavis HealthSacramentoCAUSA Department of Research College of MedicineCalifornia Northstate UniversityElk GroveCAUSA

Background and Objective:Advances in teleophthalmology and artificial intelligence(AI)for diabetic retinal screening is of growing public health ***,only 30–40%of patients with diabetes adhere to recommended diabetes screening *** enhance early detection and reduce vision threatening complications,there has been a growing number of teleophthalmology programs and novel AI algorithms with the aim to improve eye care *** purpose of this review is to assess current literature on teleophthalmology and AI for use in diabetic retinopathy(DR)screening,and to discuss advances and barriers to these innovative ***:Literature review involving teleophthalmology and AI for DR screening,with focus on the past *** Content and Findings:Teleophthalmology has demonstrated the ability to increase DR screening rates,enable earlier eye care access,and reduce healthcare *** AI-based DR screening programs appear accurate and effective,but detection of other ocular pathologies is still under development and not yet approved in the United ***,technological,financial,and legal barriers limit widespread adoption and long-term sustainability of teleophthalmology ***:The use of teleophthalmology and AI algorithms expands eye care access and helps prevent vision loss from DR and potentially other sight threatening *** in the process utilized for arriving at a particular diagnosis or decision to refer,often referred to as the“black box”,remains a multifaceted issue within the field of telemedicine for developing trust and improving patient-centered outcomes.

关键词： Teleophthalmology artificial intelligence(AI) diabetic retinopathy(DR) screening public health

Locus coeruleus-norepinephrine: basic functions and insights into Parkinson’s disease

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Neural Regeneration Research 2020年第6期15卷 1006-1013页

作者： Bilal Abdul Bari Varun chokshi Katharina Schmidt The Solomon H.Snyder Department of Neuroscience Brain Science InstituteKavli Neuroscience Discovery InstituteThe Johns Hopkins University School of MedicineBaltimoreMDUSA Department of Physiology The Johns Hopkins University School of MedicineBaltimoreMDUSA

The locus coeruleus is a pontine nucleus that produces much of the brain's *** its small size,the locus coeruleus is critical for a myriad of functions and is involved in many neurodegenerative and neuropsychiatric *** this review,we discuss the physiology and anatomy of the locus coeruleus system and focus on norepinephrine's role in synaptic *** highlight Parkinson's disease as a disorder with motor and neuropsychiatric symptoms that may be understood as aberrations in the normal functions of locus coeruleus.

关键词： catecholamines copper neurodegenerative diseases neuromodulation neuronal circuits neuropsychiatric symptoms noradrenaline synaptic plasticity

LOCA FREQUENCY EVALUATION USING EXPERT ELICITATION

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LOCA FREQUENCY EVALUATION USING EXPERT ELICITATION

Simultaneous bilateral shoulder and bilateral central acetabular fracture dislocation： What to do？

第十八届国际反应堆结构力学大会

作者： Robert Lee Tregoning Lee Richard Abramson Paul Michael Scott Nilesh chokshi United States Nuclear Regulatory Commission United States Nuclear Regulatory Commission Battelle Memorial Institute United States Nuclear Regulatory Commission

＜正＞ The double-ended-guillotine break （DEGB） criterion of the largest primary piping system in the plant, which generally provides the limiting condition for the emergency core cooling system requirements, is widely recognized as an extremely unlikely event. As a result, US Nuclear Regulatory Commission （NRC） staff are currently considering a risk-informed revision of the design-basis break size requirements for commercial nuclear power plants. In support of this effort, loss-of-coolant accident （LOCA） frequency estimates have been developed using an expert elicitation process by consolidating service history data and

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Chinese Journal of Traumatology 2016年第1期19卷 59-62页

作者： Hardik Sheth Abhijeet Ashok Salunke Ramesh Panchal Jimmy chokshi G.I. Nambi Saranjeet Singh Amit Patel Ranu Sheth Pramukswami Medical College Anand. Gujrat. India

Musculoskeletal injuries following seizures have a high morbidity and mortality. These injuries are often missed and the diagnosis is delayed due to a lack of clinical suspicion and appropriate investigations. We report a case of 72 years old male with simultaneous bilateral central acetabular fracture dislocation and bilateral posterior shoulder fracture dislocation secondary to an epileptic seizure. Present study high- lights the significance of clinical suspicion and clinico-radiological evaluation for diagnosis of a rare injury following episode of seizures. Simultaneous fracture dislocation of all four limbs treated with a holistic approach can lead to a good functional recovery. Surgical management with open reduction and internal fixation is preferred and replacement arthroplasty should be reserved for cases with implant failure and elderly patients.

关键词： Epilepsy Seizures Acetabulum Fracture Dislocation Shoulder

REVIEW OF NUCLEAR POWER REACTOR COOLANT SYSTEM LEAKAGE EVENTS AND LEAK DETECTION REQUIREMENTS

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REVIEW OF NUCLEAR POWER REACTOR COOLANT SYSTEM LEAKAGE EVENT...

拉米夫定联合白介素-12治疗慢性乙型肝炎:抗病毒活性和免疫活性

第十八届国际反应堆结构力学大会

作者： N.C. chokshi M. Srinivasan D. S. Kupperman P. Krishnaswamy U.S. Nuclear Regulatory Commission U.S. Nuclear Regulatory Commission Argonne National Laboratory Eng. Mechanics Corporation of Columbus

＜正＞ In response to the vessel head event at the Davis-Besse reactor, the U.S. Nuclear Regulatory Commission （NRC） formed a Lessons Learned Task Force （LLTF）. Four action plans were formulated to respond to the recommendations of the LLTF. The action plans involved efforts on barrier integrity, stress corrosion cracking （SCC）, operating experience, and inspection and program management. One part of the action plan on barrier integrity was an assessment to identify potential safety benefits from changes in requirements pertaining to

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世界核心医学期刊文摘（胃肠病学分册） 2006年第5期2卷 42-43页

作者： Rigopoulou E.I. Suri D. chokshi S. N.V. Naoumov 陈瑜 Institute of Hepatology University College London 69-75 Chenies Mews London WC1E 6HX United Kingdom Dr.

Interleukin-12 (IL-12) is an immunomodulatory cytokine that promotes cellular immunity. Pre-clinical data suggest that IL-12 inhibits hepatitis B virus (HBV) replication by stimulating interferon-gamma (IFN-γ ) production. We investigated whether a combination treatment with lamivudine plus recombinant human interleukin-12 (rhIL-12) will result in a greater and prolonged suppression of HBV replication in comparison with lamivudine monotherapy. Fifteen patients with HBeAg-positive chronic hepatitis B were randomized to receive either lamivudine alone for 24 weeks (group 1); combination of lamivudine for 16 weeks and rhIL-12 (200 ng/kg twice weekly), starting 4 weeks after initiation of lamivudine, for 20 weeks (group 2), or the same schedule as for group 2, with lamivudine and a higher dose of rhIL-12 (500 ng/kg, group 3). Serum HBV DNA levels, T-cell proliferation, frequency of virus-specific T-cells, and IFN-γ production were evaluated serially during and 24 weeks posttreatment. Lamivudine plus rhIL-12/500 showed greater antiviral activity than lamivudine monotherapy. However, after stopping lamivudine in groups 2 and 3, serum HBV DNA increased significantly despite continuing rhIL-12 administration. Lamivudine plus rhIL-12 treatment was associated with a greater increase in virus-specific T-cell reactivity, IFN-γ production, and an inverse correlation between the frequency of IFN-γ -producing CD4+ T-cells and viremia. The T-cell proliferative response to HBcAg did not differ between the three groups. In conclusion, the addition of IL-12 to lamivudine enhances T-cell reactivity to HBV and IFN-γ production. However, IL-12 does not abolish HBV replication in HBeAg-positive patients and does not maintain inhibition of HBV replication after lamivudine withdrawal.

关键词：拉米夫定治疗慢性乙型肝炎患者白介素-12 抗病毒活性联合治疗免疫活性乙型肝炎病毒(HBV) rhIL-12 HBV的复制 HBeAg阳性

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从褐煤制取腐植酸类肥料的发展研究情况综述

腐植酸 1989年第3期 63-65,52页

作者： Dr.R.K.Shah Dr.M.R.chokshi Dr.B.C.Joshi Prof.V.C.Lala 徐晓

本文献综述是关于从褐煤制取合成腐植酸类物质的发展研究。褐煤腐植酸对土壤肥力、土壤形成以及植物营养和作物生长都是非常有益的。从褐煤腐植酸制备的各种金属腐植酸盐对植物的新陈代谢起很重要的作用。这些物质就是大家熟知的褐煤腐... 详细信息

本文献综述是关于从褐煤制取合成腐植酸类物质的发展研究。褐煤腐植酸对土壤肥力、土壤形成以及植物营养和作物生长都是非常有益的。从褐煤腐植酸制备的各种金属腐植酸盐对植物的新陈代谢起很重要的作用。这些物质就是大家熟知的褐煤腐植酸——腐植酸类肥料。

关键词：褐煤制取腐植酸肥料