检索结果-南通市图书馆

Stable operation of highly loaded pure Si-Fe anode under ambient pressure via carboxy silane-directed robust solid electrolyte interphase

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第7期94卷 568-576页

作者： Guntae Lim Dong Guk Kang Hyeon Gyu lee yen Hai Thi Tran Kihun An Junghyun Choi Kwang Chul Roh Do Youb Kim Seung-Wan Song Department of Chemical Engineering&Applied Chemistry Chungnam National University Daejeon 34134Republic of Korea Energy Storage Materials Center Korea Institute of Ceramic Engineering&TechnologyJinju 52851Republic of Korea Advanced Energy Materials Research Center Korea Research Institute of Chemical TechnologyDaejeon 34114Republic of Korea

Incorporation of higher content Si anode material beyond 5 wt% to Li-ion batteries(LIBs)is challenging,owing to large volume change,swelling,and solid electrolyte interphase(SEI)instability ***,a strategy of diacetoxydimethylsilane(DAMS)additive-directed SEI stabilization is proposed for a stable operation of Si-0.33FeSi_(2)(named as Si-Fe)anode without graphite,which provides siloxane inorganics and organics enrichment that compensate insufficient passivation of fluoroethylene carbonate(FEC)additive and reduce a dependence on *** stable cycling performance of highly loaded(3.5 mA h cm^(-2))pure Si-Fe anode is achieved with 2 wt%DAMS combined with 9 wt%FEC additives under ambient pressure,yielding high capacity 1270 mA h g^(-1)at 0.5 C and significantly improved capacity retention of 81% after 100 cycles,whereas short circuit and rapid capacity fade occur with FEC only ***-directed robust SEI layer dramatically suppresses swelling and particles crossover through separator,and therefore prevents short circuit,demonstrating a possible operation of pure Si or Sidominant anodes in the next-generation high-energy-density and safe LIBs.

关键词： High-energy Li-ion battery Pure Si-Fe anode without graphite Silane additive SEI layer Suppressed swelling

Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第11期19卷 2543-2552页

作者： Sam Enayati Karen Chang Anton Lennikov Menglu Yang Cherin lee Ajay Ashok Farris Elzaridi Christina yen Kasim Gunes Jia Xie Kin-Sang Cho Tor Paaske Utheim Dong Feng Chen Schepens Eye Research Institute of Massachusetts Eye and Ear Department of OphthalmologyHarvard Medical SchoolBostonMAUSA Institute of clinical medicine Faculty of MedicineUniversity of OsloOsloNorway Department of Medical Biochemistry Oslo University HospitalUniversity of OsloOsloNorway Department of Ophthalmology Drammen HospitalVestre Viken Hospital TrustDrammenNorway Department of Histology and Embryology School of MedicineMarmara UniversityIstanbulTurkiye

Retinitis pigmentosa is a hereditary retinal disease that affects rod and cone photoreceptors,leading to progressive photoreceptor *** research supports the beneficial effect of electrical stimulation on photoreceptor *** study aims to identify the most effective electrical stimulation parameters and functional advantages of transcorneal electrical stimulation(tcES)in mice affected by inherited retinal ***,the study seeked to analyze the electric field that reaches the retina in both eyes in mice and post-mortem *** this study,we recorded waveforms and voltages directed to the retina during transcorneal electrical stimulation in C57BL/6J mice using an intraocular needle probe with rectangular,sine,and ramp *** investigate the functional effects of electrical stimulation on photoreceptors,we used human retinal explant cultures and rhodopsin knockout(Rho^(-/-))mice,demonstrating progressive photoreceptor degeneration with *** retinal explants isolated from the donors’eyes were then subjected to electrical stimulation and cultured for 48 hours to simulate the neurodegenerative environment in *** density was evaluated by rhodopsin *** vivo Rho^(-/-)mice were subjected to two 5-day series of daily transcorneal electrical stimulation using rectangular and ramp *** function and visual perception of mice were evaluated by electroretinography and optomotor response(OMR),*** was used to assess the morphological and biochemical changes of the photoreceptor and bipolar cells in mouse *** recordings indicated effective delivery of rectangular,sine,and ramp waveforms to the retina by transcorneal electrical stimulation,of which the ramp waveform required the lowest *** of the total conductive resistance of the post-mortem human compared to the mouse eyes indicated higher cornea-to-retina resistance in human *** tem

关键词： bipolar cells electrical stimulation neuroprotection photoreceptor degeneration retina retinal explants retinitis pigmentosa transcorneal electrical stimulation waveform

A Single Mooring System with Sag-Extensibility and Flexural Rigidity Applied to Offshore Platform

在线全文

学校读者我要写书评

暂无评论

China Ocean Engineering 2013年第3期27卷 335-350页

作者： M.-C. Tsai hsien Hua lee Jun-yen lee S.-S. Hsiao Department of Marine Environment and Engineering National Sun Yat-sen University Department of Harbor and River Engineering National Taiwan Ocean University

Floating platform system has been extensively used in ocean exploitation, particularly for a tension-leg platform （TLP） system in deep water. Most of the TLPs are multi-mooring systems, where multi-joints are connected to the tension-legs so that the platform is not allowed to twist freely and may subject to enormous force induced by large incident waves in the weak-direction of the structure. This study aims to exploit a single moored offshore platform system that may attract less force and can be operated with less effort. In our analysis, in addition to mechanical properties of the tether, two important properties are also taken into consideration for the single mooring tether with expanded cross sectional dimension and utilization of stronger material, namely, the sag-extensibility and the flexural rigidity. Finally, the dynamic structural behavior produced by the mechanical effects on the new system is investigated and compared with that of traditional design while the wave-structure interactions of large body are also accounted for. Our study finds that the neglect of sag-extensibility or the flexural rigidity of large, strong mooring cable may result in a conservative but not necessarily safe design.

关键词： tention leg platform (TLP) single mooring platform system flexural rigidity sag extensibility wave-structure interactions

KinasePhos 3.0:Redesign and Expansion of the Prediction on Kinase-specific Phosphorylation Sites

在线全文

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2023年第1期21卷 228-241页

作者： Renfei Ma Shangfu Li Wenshuo Li Lantian Yao hsien-Da Huang Tzong-Yi lee Warshel Institute for Computational Biology School of MedicineThe Chinese University of Hong KongShenzhen 518172China School of Life Sciences University of Science and Technology of ChinaHefei 230027China School of Science and Engineering The Chinese University of Hong KongShenzhen 518172China School of Life and Health Sciences School of MedicineThe Chinese University of Hong KongShenzhen 518172China

The purpose of this work is to enhance KinasePhos,a machine learning-based kinasespecific phosphorylation site prediction *** verified kinase-specific phosphorylation data were collected from PhosphoSitePlus,UniProtKB,the GPS 5.0,and *** total,41,421 experimentally verified kinase-specific phosphorylation sites were identified.A total of 1380 unique kinases were identified,including 753 with existing classification information from KinBase and the remaining 627 annotated by building a phylogenetic *** on this kinase classification,a total of 771 predictive models were built at the individual,family,and group levels,using at least 15 experimentally verified substrate sites in positive training *** improved models demonstrated their effectiveness compared with other prediction *** example,the prediction of sites phosphorylated by the protein kinase B,casein kinase 2,and protein kinase A families had accuracies of 94.5%,92.5%,and 90.0%,*** average prediction accuracy for all 771 models was 87.2%.For enhancing interpretability,the SHapley Additive exPlanations(SHAP)method was employed to assess feature *** web interface of KinasePhos 3.0 has been redesigned to provide comprehensive annotations of kinase-specific phosphorylation sites on multiple ***,considering the large scale of phosphoproteomic data,a downloadable prediction tool is available at https://***/KinasePhos/*** or https://***/tom-209/KinasePhos-3.0-executable-file.

关键词： Kinase-specific phosphorylation Phosphorylation site prediction Phosphorylation SHAP feature importance Kinase

Endoscopic salvage therapy after failed biliary cannulation using advanced techniques:A concise review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第29期28卷 3803-3813页

作者： Yung-Kuan Tsou Kuang-Tse Pan Mu hsien lee Cheng-Hui Lin Department of Gastroenterology and Hepatology Chang Gung Memorial HospitalTaoyuan 333Taiwan Department of Medicine Chang Gung UniversityTaoyuan 333Taiwan Department of Medical Imaging and Intervention Chang Gung Memorial HospitalTaoyuan 333Taiwan

Therapeutic endoscopic retrograde cholangiopancreatography(ERCP)begins with successful biliary ***,it is not always be *** failure of the initial ERCP is attributed to two main aspects:the papilla/biliary orifice is endoscopically accessible,or it is *** the papilla/biliary orifice is accessible,bile duct cannulation failure can occur even with advanced cannulation techniques,including double guidewire techniques,transpancreatic sphincterotomy,needle-knife precut papillotomy,or *** is currently no consensus on the next steps of treatment in this ***,this review aims to propose and discuss potential endoscopic options for patients who have failed ERCP due to difficult bile duct *** options include interval ERCP,percutaneous-transhepatic-endoscopic rendezvous procedures(PTE-RV),and endoscopic ultrasound-assisted rendezvous procedures(EUS-RV).The overall success rate for interval ERCP was 76.3%(68%-79% between studies),and the overall adverse event rate was 7.5%(0-15.9% between studies).The overall success rate for PTE-RV was 88.7%(80.4%-100%between studies),and the overall adverse event rate was 13.2%(4.9%-19.2% between studies).For EUS-RV,the overall success rate was 82%-86.1%,and the overall adverse event rate was 13%-15.6%.Because interval ERCP has an acceptably high success rate and lower adverse event rate and does not require additional expertise,facilities,or other specialists,it can be considered the first choice for salvage ***-RV can also be considered if local experts are *** patients in urgent need of biliary drainage,PTE-RV should be considered.

关键词： Difficult biliary cannulation Endoscopic ultrasound Rendezvous Endoscopic retrograde cholangiopancreatography Percutaneous transhepatic biliary drainage Interval

Cholecystectomy for asymptomatic gallstones:Markov decision tree analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第29期10卷 10399-10412页

作者： Brian Juin hsien lee Qai Ven Yap Jee Keem Low Yiong Huak Chan Vishal G Shelat lee Kong Chian School of Medicine Nanyang Technological UniversitySingapore S308232Singapore Biostatistics Unit Yong Loo Lin School of MedicineNational University of SingaporeSingapore S117597Singapore Department of General Surgery Tan Tock Seng HospitalSingapore S308433Singapore

Gallstones are a common public health problem,especially in developed *** are an increasing number of patients who are diagnosed with gallstones due to increasing awareness and liberal use of imaging,with 22.6%-80% of gallstone patients being asymptomatic at the time of *** being asymptomatic,this group of patients are still at life-long risk of developing symptoms and complications such as acute cholangitis and acute biliary ***,while early prophylactic cholecystectomy may have some benefits in selected groups of patients,the current standard practice is to recommend cholecystectomy only after symptoms or complications *** reviewing the current evidence about the natural course of asymptomatic gallstones,complications of cholecystectomy,quality of life outcomes,and economic outcomes,we recommend that the option of cholecystectomy should be discussed with all asymptomatic gallstone *** of material information is essential for patients to make an informed choice for prophylactic *** is for the patient to decide on watchful waiting or prophylactic cholecystectomy,and not for the medical community to make a blanket policy of watchful waiting for asymptomatic gallstone *** patients with high-risk profiles,it is clinically justifiable to advocate cholecystectomy to minimize the likelihood of morbidity due to complications.

关键词： Asymptomatic Cholecystectomy Cholelithiasis Gallbladder Gallstone

Using a consensus acupoints regimen to explore the relationship between acupuncture sensation and lumbar spinal postoperative analgesia: A retrospective analysis of prospective clinical cooperation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2022年第4期20卷 329-337页

作者： yen-Lin Chao Yi-Ai Rau Hong-Sheng Shiue Jiun-Lin Yan Yuan-Yun Tang Shao-Wen Yu Bo-Yan Yeh yen-Lung Chen Tsung-hsien Yang Shu-Chen Cheng Yi-Wen Hsieh Hsin-Chia Huang Fu-Kuang Tsai Yu-Sheng Chen Geng-Hao Liu Division of Acupuncture and Moxibustion Department of Traditional Chinese MedicineChang Gung Memorial HospitalTaoyuan 333TaiwanChina School of Traditional Chinese Medicine College of MedicineChang Gung UniversityTaoyuan 333TaiwanChina Department of Neurosurgery Keelung Chang Gung Memorial HospitalKeelung 204TaiwanChina Department of Traditional Chinese Medicine New Taipei Municipal TuCheng HospitalChang Gung Memorial HospitalNew Taipei 236TaiwanChina Sleep Center Chang Gung Memorial HospitalTaoyuan 333TaiwanChina

Objective: This study evaluated the effectiveness of acupuncture treatment on postoperative pain in patients with degenerative lumbar spine disease, and explored the relationship between the postoperative analgesic effect of acupuncture and the sensation of acupuncture experienced by the ***: This retrospective study analyzed the medical records of 97 patients who had undergone an operation by the same surgeon due to degenerative lumbar disease. These patients were divided into acupuncture group(n = 32), patient-controlled analgesia(PCA) group(n = 27), and oral analgesia group(n = 38) according to the different postoperative analgesic methods. During their hospitalization, patients completed daily evaluations of their pain using a visual analogue scale(VAS), and injection times of supplemental meperidine were recorded. Also, the Chinese version of the Massachusetts General Hospital Acupuncture Sensation Scale(C-MASS) was used in the acupuncture ***: Each of the three treatment groups showed significant reductions in postoperative pain, as shown by reduced VAS scores. The acupuncture group, however, had less rebound pain(P < 0.05) than the other two groups. Both the acupuncture and PCA groups experienced acute analgesic effects that were superior to those in the oral analgesia group. In addition, the higher the C-MASS index on the second day after surgery, the lower the VAS score on the fourth day after surgery. There was also a significant difference in the“dull pain” in the acupuncture ***: The results demonstrated that acupuncture was beneficial for postoperative pain and discomfort after simple surgery for degenerative spinal disease. It is worth noting that there was a disproportionate relevance between the patient’s acupuncture sensation and the improvement of pain VAS score.

关键词： Acupuncture analgesia Postoperative period Neurodegenerative diseases Lumbosacral region Acupuncture sensation De-qi

Predicting portal venous anomalies by left-sided gallbladder or rightsided ligamentum teres hepatis: A large scale, propensity scorematched study

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2023年第27期29卷 4344-4355页

作者： Hsuan-Yin Lin Rheun-Chuan lee Jyh-Wen Chai Chiann-Yi Hsu yen Chou Hsuen-En Hwang Chien An Liu Nai-Chi Chiu Ho-Hsian yen Department of Radiology Taichung Veterans General HospitalTaichung 407219Taiwan Department of Radiology Taipei Veterans General HospitalTaipei 11267Taiwan School of Medicine National Yang Ming Chiao Tung UniversityTaipei 112Taiwan Department of Medical Research Taichung Veterans General HospitalTaichung 40705Taiwan Department of Radiology Fu Jen Catholic University HospitalTaipei 24352Taiwan Department of Radiology Far Eastern Memorial HospitalNew Taipei City 220Taiwan

BACKGROUND Right-sided ligamentum teres(RSLT)is often associated with portal venous anomalies(PVA)and is regarded as a concerning feature for hepatobiliary *** studies consider RSLT to be one of the causes of left-sided gallbladder(LGB),leading to the hypothesis that LGB must always be present with ***,some cases have shown that right-sided gallbladder(RGB)can also be present in livers with *** To highlight the rare variation that RSLT may not come with LGB and to determine whether ligamentum teres(LT)or gallbladder location is reliable to predict *** This study retrospectively assessed 8552 contrast-enhanced abdominal computed tomography examinations from 2018 to 2021[4483 men,4069 women;mean age,59.5±16.2(SD)years].We defined the surrogate outcome as major *** cases were divided into 4 subgroups according to gallbladder and LT *** one hand,we analyzed PVA prevalence by LT locations using gallbladder location as a controlled variable(n=36).On the other hand,we controlled LT location and computed PVA prevalence by gallbladder locations(n=34).Finally,we investigated LT location as an independent factor of PVA by using propensity score matching(PSM)and inverse probability of treatment weighting(IPTW).RESULTS We found 9 cases of RSLT present with *** the LGB cases,RSLT is associated with significantly higher PVA prevalence than typical LT[80.0%vs 18.2%,P=0.001;OR=18,95%confidence interval(CI):2.92-110.96].When RSLT is present,we found no statistically significant difference in PVA prevalence for RGB and LGB cases(88.9%vs 80.0%,P>0.99).Both PSM and IPTW yielded balanced cohorts in demographics and gallbladder *** RSLT group had a significantly higher PVA prevalence after adjusted by PSM(77.3%vs 4.5%,P<0.001;OR=16.27,95%CI:2.25-117.53)and IPTW(82.5%vs 4.7%,P<0.001).CONCLUSION RSLT doesn't consistently coexist with *** can predict PVA independently while the gallbladder location does not serve as a suf

关键词： Right-sided ligamentum teres Left-sided gallbladder Portal venous anomalies Inverse probability of treatment weighting Average treatment effect in the treated

Clinical values of Barcelona Clinic Liver Cancer subgroup and up-to-7 criteria in intermediate stage hepatocellular carcinoma with transcatheter arterial chemoembolization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第21期10卷 7275-7284页

作者： Shou-Wu lee yen-Chun Peng Han-Chung Lien Chung-Wang Ko Chun-Fang Tung Chi-Sen Chang Division of Gastroenterology and Hepatology Department of Internal MedicineTaichung Veterans General HospitalTaichung 40705Taiwan Department of Internal Medicine Yang Ming Chiao Tung UniversityTaipei 112304Taiwan Department of Post-Baccalaureate Medicine College of MedicineChung Hsing UniversityTaichung 40227Taiwan Department of Internal Medicine Chung Shan Medical UniversityTaichung 40201Taiwan

BACKGROUND Transarterial chemoembolization(TACE)is a recommended treatment for patients with intermediate stage hepatocellular carcinoma(HCC)but with variable treatment *** To determine factors for predicting outcomes of TACE in patients with intermediate stage B *** Patients with Barcelona Clinic Liver Cancer(BCLC)stage B HCC who underwent TACE as the primary treatment were enrolled at Taichung Veterans General Hospital from January 2005 to December *** were assigned to either the objective responder(OR)group or the non-OR group according to mRECIST *** and radiological characteristics were compared between the 2 *** overall survival of enrolled subjects was *** In 128 enrolled patients,66(51.6%)were in the OR group and 62(48.4%)in the non-OR *** with the non-OR group,the OR group had a significantly smaller HCC size(6.55 cm vs 9.50 cm,P=0.001)and was within the up-to-7 criteria(50%vs 26.7%,P=0.001).After multivariable analyses,these significant associations still *** survival rate of all the subjects averaged 20.65±13.26 *** survival rate at 1-year was 64.8%,2-year was 46.9%,and 3-year was 31.2%.For those patients with OR to TACE,smaller tumor size and within up-to-7 criteria were associated with significantly better overall *** patients with subgroup B1 had the highest OR ratio(75%)and better overall survival(26.70±12.07 mo)after *** BCLC stage B HCC patients with smaller tumor size or within up-to-7 criteria had better survival outcomes to *** stage B subgroup is useful to predict refractoriness to TACE.

关键词： Hepatocellular carcinoma Objective response Overall survival Transcatheter arterial chemoembolization Barcelona Clinic Liver Cancer