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Acute pancreatitis and amiodarone:A case report

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World Journal of Gastroenterology 2007年第6期13卷 975-977页

作者： yen-Yuan Chen Ching-Yu Chen Kai-Kuen Leung Department of Family Medicine National Taiwan University Hospital Taipei Taiwan China

Amiodarone, a class Ⅲ antiarrhythmic drug, is one of the most effective drugs used in the treatment of ventricular and paroxysmal supraventricular tachyarrhythmia. Adverse effects of amiodarone including pulmonary toxicity, hepatotoxicity, aggravation of arrhythmia, and thyroid diseases are well understood. A 66-year old woman with acute pancreatitis was admitted to our hospital with the complaint of epigastralgia radiating to both flanks for two months. Her symptoms and elevation of pancreatic enzymes did not respond to conventional medical treatment of pancreatitis for 18 d. No known causal factors for pancreatitis such as biliary tract stone, hypertriglyceridemia and alcohol consumption could be identified. Under the suspicion of amiodarone-induced acute pancreatitis, amiodarone was substituted by propafenone. Her symptoms soon alleviated and serum lipase level declined. Three months after hospital discharge, the abdominal pain did not recur. Amiodarone was approved to treat recurrent ventricular fibrillation or sustained ventricular tachyarrhythmia that has been resistant to other medications since 1986. Pancreatitis is a very rare adverse effect associated with the use of amiodarone, and only four cases of amiodarone-induced pancreatitis have been reported in literature. We report a patient who developed acute pancreatitis during amiodarone therapy.

关键词： Acute pancreatitis Amiodarone Amylase Lipase

AI-Assisted approach for building energy and carbon footprint modeling

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Energy and AI 2021年第3期5卷 201-208页

作者： Chih-yen Chen Kok Keong Chai Ethan Lau School of Electronic Engineering and Computer Science Queen Mary University of LondonUnited Kingdom

This paper proposes an energy and carbon footprint modelling using artificial intelligence technique to assess the impact of occupant density for various types of office *** use EnergyPlus to simulate energy con-sumption,and then estimate the related CO₂emissions based on three years(2016–2018)of Actual Meteoro-logical Year(AMY)weather *** occupant densities were used to evaluate the annual energy consumption and CO₂*** this work,a robust deep learning technique of long short-term memory(LSTM)model was established to predict the time-series energy consumption and CO₂emissions.A power exponential curve was suggested to correlate the behaviour of annual energy and CO₂emission for occupant densities range from 10 to 100 m2/person for each office building *** results of LSTM model show high prediction performance and small variations within the three types of office building data,which can be applied to the similar building model to predict and optimise energy consumption and CO₂emission.

关键词： Building energy simulation and benchmarking Carbon footprint Occupant density Artificial intelligence Long short-term memory(LSTM) Smart city

Unusual presentation of cutaneous metastasis from bladder urothelial carcinoma

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Chinese Journal of Cancer Research 2013年第3期25卷 362-365页

作者： Chin-Pao Chang I-yen Lee Hung-Jen Shih Division of Urology Department of Surgery Changhua Christian Hospital

Cutaneous metastases from urothelial carcinoma of the bladder are a rare disease. In previous reports, the most common metastatic cutaneous lesions were non-tender nodules on the abdominal skin. We report a patient with bladder urothelial carcinoma with cutaneous metastases initially presenting as right leg and suprapubic lymphedema. Bladder tumor was the incidental finding by magnetic resonance venography. Urothelial carcinoma （clinical stage IV） was diagnosed, and chemotherapy was performed. Extensive painful erythematous plaques with an erysipelas-like appearance located on the suprapubic area, chest and abdomen were noted, and cutaneous metastases were confirmed by histopathology. Subsequently, extensive scrotal and prepuce ulcerative changes developed. This paper reports a rare case of extensive cutaneous metastasis of bladder urothelial carcinoma who presented an interesting clinical course.

关键词： Bladder skin metastasis lymphedema

Successful endoscopic sclerotherapy for cholecystojejunostomy variceal bleeding in a patient with pancreatic head cancer

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World Journal of Gastroenterology 2010年第1期16卷 123-125页

作者： Yu-Chun Hsu Hsu-Heng yen Maw-Soan Soon Department of Gastroenterology Changhua Christian Hospital

Variceal bleeding outside the esophagus and stomach is rare but important because of its difficult diagnosis and *** from cholecystojejunostomy varices has been reported to be a late complication of palliative biliary surgery for chronic *** ectopic variceal bleeding has never been reported after palliative surgery for pancreatic cancer,probably because of the limited lifespan of these patients. Herein,we report our successful experience using endoscopic cyanoacrylate sclerotherapy to treat bleeding from cholecystojejunostomy varices in a 57-year-old man with pancreatic head *** our knowledge,this is the first case report in the literature of this rare complication.

关键词： Ectopic varix Pancreatic cancer Cholecystojejunostomy Sclerotherapy

Training the old dog new tricks: the applications of the Biginelli reaction in polymer chemistry

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Science China Chemistry 2016年第12期59卷 1541-1547页

作者： Yuan Zhao Haibo Wu Zilin Wang yen Wei Zhiming Wang Lei Tao Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology(Ministry of Education) Department of ChemistryTsinghua University School of Petrochemical Engineering Changzhou University

Recently, the Biginelli reaction, one of the most famous multicomponent reactions, has been introduced into the polymer chemistry to highly efficiently synthesize some interesting functional polymers. In this mini-review, several applications of the Biginelli reaction in polymer chemistry have been summarized, including polycondensation, post-polymerization modification,one-pot synthesis of well-defined polymer, etc. Meanwhile, the utilization of the Biginelli reaction in material science and chemical biology, and the future development of the Biginelli reaction in polymer chemistry have also been discussed.

关键词： Biginelli reaction functional polymer synthesis polycondensation

Multifunctional Fluorescent Magnetic Nanoparticles： Synthesis, Characterization and Targeted Cell Imaging Applications

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Chinese Journal of Chemistry 2017年第6期35卷 977-983页

作者： Lilin Zhou, Xiaoyong Zhang Lei Liu yen Wei Jinying Yuan Key Lab of Organic Optoelectronic & Molecular Engineering Department of Chemistry Tsinghua University Beijing 100084 China

Multifunctional fluorescent magnetic nanoparticles （Fe3O4@SiO2-PLLA-RhB/FA） with cell recognition ability were synthesized through conjugation of magnetic nanoparticles with folic acid （FA） and Rhodamine B. To verity their potential biomedical applications, biocompatibility as well as cell imaging applications of the multifunctional nanoparticles were further investigated. Results showed that these fluorescent magnetic nanoparticles are well bio- compatible with NIH-3T3 cells and HeLa cells. More importantly, these nanoparticles could be selectively taken up by HeLa cells （FA receptor positive） as evidenced by laser scanning confocal microscopy, suggesting their potential for biological imaging applications. Given their excellent biocompatibility and multifunctional characteristics, weexpect that the fluorescent magnetic nanoparticles could be promising for various biomedical applications.

关键词： fluorescent magnetic particles biological imaging multifunctional biocompatibility

Characterization of crud deposited on fuel rods under HWC environment in Kuosheng Nuclear Power Plant

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Nuclear Science and Techniques 2016年第1期27卷 141-148页

作者： tsuey-lin tsai te-yen su tsung-yuan wang tsen-yu yang Chemistry Division Institute of Nuclear Energy ResearchLongtanTaoyuanTaiwanChina

Under normal water chemistry conditions, the oxygen and hydrogen peroxide produced by water radiolysis in the coolant of boiling water reactors(BWRs) can lead to intergranular stress corrosion cracking in the constituent materials of plant components. This fact has led to the wide-scale adoption of hydrogen water chemistry(HWC) in the nuclear industry to counteract these *** study seeks to characterize the metallic composition and the surface properties of the constituent materials of plant components in order to determine their effects on the accumulation of chalk river unidentified deposits(crud) on fuel rods in the BWR Unit-1 of the Kuosheng Nuclear Power Plant in Taiwan. Inductively coupled plasma-atomic emission spectroscopy was used to calculate the concentrations of surface crud and gamma spectrometry was used to determine the radioactivity of the corrosion products, as well as their axial distribution across the surface of the fuel rods. X-ray diffraction analysis and scanning electron microscopy/energy-dispersive X-ray spectroscopy were used to identify the crystalline phase and morphology of the crud as irregular shapes and flakes. The amount of crud deposited during the fourth fuel cycle exceeded that of the third fuel cycle due to extended burn-up time. Our analytical results indicate that the implementation of HWC had no significant effect on the characteristics of subsequent crud.

关键词：燃料棒核电站电感耦合等离子体原子发射光谱法表征沉积 X射线衍射分析反应堆冷却剂系统扫描电子显微镜

Landscape structure and bird's diversity in the rural areas of Taiwan

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Journal of Environmental Sciences 2003年第2期15卷 241-248页

作者： Chun-yen-Chang (Department of Horticulture, “National Chung Hsing University”, Taichung, Taiwan, China) Department of Horticulture National Chung Hsing University Taichung Taiwan

This study tries to discuss the relationship between landscape structure and organisms in the perspective of landscape architecture. The research hypotheses were then proposed as (1) there are relationships between landscape structure indexes and birds' diversity in the rural areas of Taiwan; (2) the relationships between landscape structure and birds' diversity will be different in different hierarchical levels. In order to increase the bird species, landscape planners could tries to increase the density of water bodies, but decrease the farms and human planted woods. Decrease the density of constructed and human planted grasslands. Increase the area of un-worked acres, natural grasslands, and the area of water bodies and circular the water bodies and natural forest. In order to increase birds' diversity, landscape planners could decrease the concentration of paved areas. Concentrate the human planted trees to increase the core areas of woodlands. Increase the area of natural grassland circular. In order to increase the total number of birds in the planning areas, landscape planners could scattered the paved areas and lengthen the constructed areas. Decreases the core region of the constructed areas. Increase the area of un-worked acres and water bodies. Decrease the disturbance of both the interior area of natural and human planted woodlands and try to increase the density of water bodies.;The analysis results showed that the small grain size indexes are more suitable for the rural areas of Taiwan to capture the influential factors of bird communities. The high fragmentation of land usages in Taiwan lessens the influences of the regional landscape pattern.

关键词： landscape structure bird diversity Taiwan

Strengthening reinforced concrete beams using prestressed glass fiber-reinforced polymer-Part I: Experimental study

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2005年第8期6卷 166-174页

作者： WU Jong-hwei yen Tsong HUNG Chien-hsing LIN Yiching Department of Civil Engineering National Chung-Hsing University 40227 Taiwan ChinaDepartment of Civil Engineering National Chung-Hsing University 40227 Taiwan ChinaDepartment of Civil Engineering National Chung-Hsing University 40227 Taiwan ChinaDepartment of Civil Engineering National Chung-Hsing University 40227 Taiwan China

This work is aimed at studying the strengthening of reinforced concrete (R. C.) beams using prestressed glass fi- ber-reinforced polymer (PGFRP). Carbon fiber-reinforced polymer (CFRP) has recently become popular for use as repair or rehabilitation material for deteriorated R. C. structures, but because CFRP material is very stiff, the difference in CFRP sheet and concrete material properties is not favorable for transferring the prestress from CFRP sheets to R. C. members. Glass fi- ber-reinforced polymer (GFRP) sheets with Modulus of Elasticity quite close to that of concrete was chosen in this study. The load-carrying capacities (ultimate loads) and the deflections of strengthened R. C. beams using GFRP and PGFRP sheets were tested and compared. T- and ⊥-shaped beams were used as the under-strengthened and over-strengthened beams. The GFRP sheets were prestressed to one-half their tensile capacities before being bonded to the T- and ⊥-shaped R. C. beams. The prestressed tension in the PGFRP sheets caused cambers in the R. C. beams without cracks on the tensile faces. The PGFRP sheets also enhanced the load-carrying capacity. The test results indicated that T-shaped beams with GFRP sheets increased in load-carrying capacity by 55% while the same beams with PGFRP sheets could increase load-carrying capacity by 100%. The ⊥-shaped beams with GFRP sheets could increase load-carrying capacity by 97% while the same beams with PGFRP sheets could increase the loading-carrying capacity by 117%. Under the same external loads, beams with GFRP sheets underwent larger deflections than beams with PGFRP sheets. While GFRP sheets strengthen R. C. beams, PGFRP sheets decrease the beams’ ductility, especially for the over-strengthened beams (⊥-shaped beams).

关键词： Strengthening Prestressed glass fiber reinforcement polymer Modulus of Elasticity R. C. beams

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