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A Recent Study Concerning the Climatic Variability over the Kingdom Saudi Arabia for the Period 1948-2018

Journal of Geoscience and Environment Protection（地球科学和环境保护期刊） 2019年第8期

作者： yehia Hafez

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Whole Exome Sequencing: Novel Genetic Polymorphisms in Saudi Arabian Attention Deficit Hyperactivity Disorder (ADHD) Children

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Natural Science 2019年第2期11卷 45-60页

作者： Neda Mostafa Bogari Amr Ahmed Amin Ashwag Aljohani Ghida Dairi Mahmoud Zaki El-Readi Anas Dannoun Udaya Raja Mohammad Adil Nermeen Qutub Suhair Alhelfawi Amal Alobaidi Derar Alqudah Hussain Banni Safaa yehia Eid Huda Balto Faisal Al-Allaf Mohiuddin Taher Hiba Saed Al-Amoodi Ahmed Fawzy Department of Medical Genetics Faculty of Medicine Umm Al-Qura University Makkah KSA Biochemistry Department Faculty of Medicine Umm Al-Qura University Makkah KSA Faculty of Medicine Ain Shams University Cairo Egypt Umm Al-Qura University Makkah KSA Biochemistry Department Faculty of Pharmacy Al-Azhar University Assuit Egypt Integrated Gulf Biosystems Jeddah KSA Special Needs Department School of Education Umm Al-Qura University Mecca KSA Sinad City for Special Needs Makkah KSA Institute of Education University of Reading Reading UK Faculty of Medicine King Abdulaziz University Jeddah KSA Science and Technology Unit Umm Al-Qura University Makkah KSA Division of Human Genetics & Genome Researches Department of Molecular Genetics and Enzymology National Research Centre Dokki Egypt

Background: Attention-deficit hyperactivity disorder (ADHD) is a widespread and debilitating disorder with relatively high prevalence in Saudi Arabia. Neuropsychological and radiological investigations have revealed that there are some differences in the components of the brain regions in children with and without ADHD. In this study we have performed whole exome sequencing (WES) in four non-familial cases of ADHD from Makkah Region to identify the genetic polymorphisms associated with the disease in our Saudi population. Methods: Exome sequencing was carried out using Ion Proton with AmpliSeq Exome library methods, and the data were analysed by Ion Reporter 5.6 software. Results: A total of 33 variants were identified from 222 genes selected from the GWAS catalogue for ADHD associated genes. However, the SNPs we identified in these genes were not reported to be associated with ADHD in previous studies. We have identified 2 novel missense variants;one in c.3451G > T;p. (Ala1151Ser) in ITGA1 gene and another is c.988G > A;p. (Ala330Thr) in SPATA13 genes. The variants rs928661, rs11150370 and rs386792899 were the only three variants that appeared on all the 4 patients studied. Six missense variants, rs16841277, rs2228209, rs2230283, rs3741883, rs1716 and rs2272606, were found in 3 different patients, respectively. However, the three documented variants are rs13166360 with bipolar disorder, rs920829 with neuropathic pain, and rs6558702 with schizophrenia. Conclusion: We have identified 2 novel variants in ADHD children. SIFT score of all variants indicates that these substitutions have damaging effects on the protein function. Further screening studies are recommended for confirmation.

关键词： Next Generation DNA Sequencing Single Nucleotide Polymorphisms Saudi Children Attention-Deficit Hyperactivity Disorder ADHD

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Exploring the factors influencing nurses' work motivation during the COVID-19 pandemic in King Faisal Hospital in Makkah al-Mukarramah, Saudi Arabia

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Nursing Communications 2022年第1期6卷 148-155页

作者： Albandre Alenezi Mari Almutairi Mohammed Saleh Alshmemri Maram Taher Alghabbashi Hala yehia Faculty of Nursing Umm Al-Qura UniversityMakkah 24382Saudi Arabia Ministry of health The Directorate of Health affairs in Northern ProvinceAr a r 91471Saudi Arabia

Background:At this time of severe budgetary constraints and worldwide nursing shortages,the nursing profession is already facing challenges in keeping its professionals motivated to work during the COVID-19 *** study explores the factors influencing nurses’work motivation during the COVID-19 pandemic in Saudi *** s:A descriptive quantitative cross-sectional study was conducted at King Faisal Hospital in Makkah al-Mukarramah,Saudi Arabia.A convenience sample of 184 nurses participated in the *** electronic self-administrative questionnaire in the English language was used to collect *** comprises two parts:demographic data and the Multidimensional Work Motivation Scale(MWMS)using a 7-point Likert *** of variance(ANOVA)and t-tests were utilized to identify the differences in MWMS scores among participants’***:The study found that the overall mean score for the MWMS scale accounted for M=81.32,SD=18.66,with the highest mean score reported for interjected regulation(M=20.19,SD=5.59).Moreover,the results revealed that 62%of the participants attained an average level on the overall *** addition,the ANOVA and t-test showed a significant overall effect of the duration of nurses’work experience,the unit of care,the number of working hours per week and salary on nurses’work motivation during COVID-19 at P<***:The study’s findings suggest that hospital administrators and nursing managers should pay careful attention to nurses’work motivation and related factors to increase nurses’quality performance,retention and satisfaction.

关键词： nurses work satisfaction motivation COVID-19 Saudi Arabia

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埃及尼罗河三角洲城市化监测

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AMBIO－人类环境杂志 1999年第7期28卷 627-631页

作者： Mohamed Sultan Michael Fiske Thomas Stein Mohamed Gamal yehia Abdel Hady Hesham El Araby Ahmed Madani Salah Mehanee Richard Becker 石培礼阿尔贡国家实验室华盛顿大学地球与行星科学系开罗大学中国科学院地理科学与资源研究所

对1972、1984和1990年在尼罗河三角洲获取的Landsat MSS和TM影象(scenes)处理的和协同配准的(coregistered)数字镶嵌图比较表明,城镇增长正危及着埃及农业的生产力。在1972、1984和1990年尼罗河三角洲的城镇面积至少分别占3.6%、4.7%和5... 详细信息

对1972、1984和1990年在尼罗河三角洲获取的Landsat MSS和TM影象(scenes)处理的和协同配准的(coregistered)数字镶嵌图比较表明,城镇增长正危及着埃及农业的生产力。在1972、1984和1990年尼罗河三角洲的城镇面积至少分别占3.6%、4.7%和5.7%,在这18年期间增长了58%。大约一半的增长出现在1984～1990年期间。如果这种趋势继续下去,到2010年埃及将因城市化而丧失农地总面积的12%。尽管事实上城镇增长主要出现在城市周围,但在几千个小村庄周围的增长却对尼罗河三角洲的农业生产构成最大的威胁。1972～1990年间,城市和大村庄的累积增长率为37%,而同期小村庄的累积增长率为77%。

关键词：尼罗河三角洲城市化监测埃及农业生产力

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The Effect of Early versus Traditional Hospital Discharge on Activities of Daily Living for Women Undergoing Elective Cesarean *** Observational Cohort Study

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Open Journal of Obstetrics and Gynecology（妇产科期刊） 2023年第3期

作者： Ahmed Mohammed Elmaraghy Rasha Elhoseny yehia Ahmed Hamdy Naguib

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Biliary fistula and late recurrence of liver hydatid cyst:Role of cystobiliary communication:A prospective multicenter study

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World Journal of Methodology 2023年第4期13卷 272-286页

作者： Tamer A A M Habeeb Mauro Podda Boris Tadic Vishal G Shelat Yaman Tokat Mohamed Ibrahim Abo Alsaad Abd-Elfattah Kalmoush Mohammed Shaaban Nassar Fawzy Metwally Mustafa Mahmoud Hassib Morsi Badawy Mohamed Sobhy Shaaban Tarek Zaghloul Mohamed Mohammed Ibrahim El Sayed Henish Hamdi Elbelkasi Mahmoud Abdou Yassin Abdelshafy Mostafa Amr Ibrahim Waleed A-Abdelhady TamerMohamed Elshahidy Mohamed Ibrahim Mansour Adel Mahmoud Moursi Mohamed Abdallah Zaitoun EhabShehata Abd-Allah Ashraf Abdelmonem Elsayed Rasha S Elsayed Ahmed M yehia Amr Abdelghani Mohamed Negm Heba Alhussein Abo-Alella Mostafa M Elaidy Department of General Surgery Faculty of Medicine Zagazig UniversitySharkia 44511Egypt Department of Surgical Science University of CagliariCagliari 09126Italy Clinic for Digestive Surgery–First Surgical Clinic University Clinical Centre of SerbiaBelgrade 11000Serbia Department of General Surgery Tan Tock Seng HospitalSingapore 018971Singapore Department of Liver Transplantation and Hepatobiliary Surgery IstanbulTurkeyInternational Liver Centerand Acibadem Hospital GroupIstanbul 34000Turkey Department of General Surgery Faculty of Medicine-Merit UniversitySohag 82511Egypt Department of General Surgery Faculty of MedicineAl-Azher UniversityCairo 11765Egypt Department of General Surgery Mataryia Teaching HospitalCairo 11765Egypt

BACKGROUND Hydatid cyst disease(HCD)is common in certain *** is associated with postoperative biliary fistula(POBF)and *** primary aim of this study was to identify whether occult cysto-biliary communication(CBC)can predict recurrent *** secondary aim was to assess the role of cystic fluid bilirubin and alkaline phosphatase(ALP)levels in predicting POBF and recurrent *** To identify whether occult CBC can predict recurrent *** secondary aim was to assess the role of cystic fluid bilirubin and ALP levels in predicting POBF and recurrent *** From September 2010 to September 2016,a prospective multicenter study was undertaken involving 244 patients with solitary primary superficial stage cystic echinococcosis 2 and cystic echinococcosis 3b HCD who underwent laparoscopic partial cystectomy with *** logistic regression analysis assessed independent factors determining biliary complications and *** There was a highly statistically significant association(P≤0.001)between cystic fluid biochemical indices and the development of biliary complications(of 16 patients with POBF,15 patients had high cyst fluid bilirubin and ALP levels),where patients with high bilirubin-ALP levels were 3405 times more likely to have biliary *** was a highly statistically significant association(P≤0.001)between biliary complications,biochemical indices,and the occurrence of recurrent HCD(of 30 patients with recurrent HCD,15 patients had high cyst fluid bilirubin and ALP;all 16 patients who had POBF later developed recurrent HCD),where patients who developed biliary complications and high bilirubin-ALP were 244.6 and 214 times more likely to have recurrent hydatid cysts,*** Occult CBC can predict recurrent *** cyst fluid bilirubin and ALP levels predicted POBF and recurrent HCD.

关键词： Cysto-biliary communication Echinococcus granulosus Hydatid disease recurrence Hydatid fluid analysis Laparoscopy

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Fetoscopy Role in Fetal Surgery and Fetal Medicine

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Open Journal of Obstetrics and Gynecology（妇产科期刊） 2019年第11期

作者： Wael S. S. Elbanna Ibrahim A. Oun Emad M. Abd Ellatif Wael R. Hablas Walid I. El Shaikh yehia A. Wafa

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