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Effects of intravascular laser phototherapy on delayed neurological sequelae after carbon monoxide intoxication as evaluated by brain perfusion imaging:A case report and review of the literature

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World Journal of Clinical Cases 2021年第13期9卷 3048-3055页

作者： Chuan-Ching Liu Chun-Sheng Hsu hsin-chen He Yuan-Yang cheng Shin-Tsu Chang Department of Physical Medicine and Rehabilitation Taichung Veterans General HospitalTaichung 407Taiwan Department of Public Health and Institute of Public Health Chung Shan Medical UniversityTaichung 402Taiwan Department of Rehabilitation Science Jenteh Junior College of MedicineNursing and ManagementMiaoli 356Taiwan School of Medicine National Yang-Ming UniversityTaipei 112Taiwan Center for Geriatrics and Gerontology Taichung Veterans General HospitalTaichung 407Taiwan Department of Physical Medicine and Rehabilitation Tri-Service General HospitalSchool of MedicineNational Defense Medical CenterTaipei 114Taiwan

BACKGROUND Delayed neurological sequelae(DNS)caused by carbon monoxide(CO)intoxication poses considerable treatment challenges for clinical *** this report,we used nuclear medicine imaging and the Mini-Mental State Examination(MMSE)to evaluate the effectiveness of intravascular laser irradiation of blood(ILIB)therapy for the management of *** SUMMARY A 51-year-old woman presented to our medical center experiencing progressive bradykinesia,rigidity of limbs,gait disturbance,and cognitive *** on her neurological deficits,laboratory tests and imaging findings,the patient was diagnosed with delayed neurological sequelae of CO *** received intensive rehabilitation and ILIB therapy during 30 sessions over 2 mo after *** single-photon emission computed tomography was performed both prior to and after ILIB *** original hypoperfusion area in bilateral striata,bilateral frontal lobe,right parietal lobe,and bilateral cerebellum showed considerable improvement after completion of *** patient’s MMSE score also increased markedly from 6/30 to 25/*** of DNS became barely detectable,and the woman was able to carry out her daily living activities *** ILIB therapy could facilitate recovery from delayed neurological sequelae in patients with CO intoxication,as demonstrated by improved cerebral blood flow and functional outcomes in our patient.

关键词： Carbon monoxide poisoning Delayed neurological sequelae Intravascular laser irradiation of blood Redistribution Single photon emission computed tomography Case report

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SpyGlass application for duodenoscope working channel inspection: Impact on the microbiological surveillance

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World Journal of Gastroenterology 2020年第26期26卷 3767-3779页

作者： Tao-Chieh Liu chen-Ling Peng Hsiu-Po Wang hsin-Hung Huang Wei-Kuo Chang Division of Gastroenterology Department of Internal MedicineTri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Department of Integrated Diagnostics&Therapeutics National Taiwan University HospitalNational Taiwan University College of MedicineTaipei 10002Taiwan Division of Gastroenterology and Hepatology Department of Internal MedicineNational Taiwan University HospitalNational Taiwan University College of MedicineTaipei 114Taiwan Division of Gastroenterology Cheng Hsin General HospitalNational Defense Medical CenterTaipei 114Taiwan

BACKGROUND Patient-ready duodenoscopes were designed with an assumed contamination rate of less than 0.4%;however,it has been reported that 5.4%of clinically used duodenoscopes remain contaminated with viable high-concern organisms despite following the manufacturer’s *** inspection of working channels has been proposed as a quality control measure for endoscope *** are few studies related to this *** To investigate the types,severity rate,and locations of abnormal visual inspection findings inside patient-ready duodenoscopes and their microbiological *** Visual inspections of channels were performed in 19 patient-ready duodenoscopes using the SpyGlass visualization system in two endoscopy units of tertiary care teaching hospitals(Tri-Service General Hospital and National Taiwan University Hospital)in *** were recorded and reviewed to evaluate the presence of channel scratches,buckling,stains,debris,and *** findings were used to analyze the relevance of microbiological *** Seventy-two abnormal visual inspection findings in the 19 duodenoscopes were found,including scratches(n=10,52.6%),buckling(n=15,78.9%),stains(n=14,73.7%),debris(n=14,73.7%),and fluids(n=6,31.6%).Duodenoscopes>12 mo old had a significantly higher number of abnormal visual inspection findings than those≤12 mo old(46 findings vs 26 findings,P<0.001).Multivariable regression analyses demonstrated that the bending section had a significantly higher risk of being scratched,buckled,and stained,and accumulating debris than the insertion *** and fluids showed a significant positive correlation with microbiological contamination(P<0.05).There was no significant positive Spearman’s correlation coefficient between negative bacterial cultures and debris,between that and fluids,and the concomitance of debris and *** result demonstrated that the presence of fluid and debris was associated with positive

关键词： Duodenoscope Working channel Visual inspection Microbiological surveillance Reprocessing Endoscope reprocessing

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Two-color multiphoton in vivo imaging with a femtosecond diamond Raman laser

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Light(Science & Applications) 2017年第1期6卷 400-407页

作者： Evan P Perillo Jeremy W Jarrett Yen-Liang Liu Ahmed Hassan Daniel C Fernée John R Goldak Andrei Bonteanu David J Spence hsin-Chih yeh Andrew K Dunn Department of Biomedical Engineering The University of Texas at AustinTX 78712USA Department of Physics The University of Texas at AustinTX 78712USA MQ Photonics Department of Physics and AstronomyMacquarie UniversitySydneyNSW 2109Australia

Two-color multiphoton microscopy through wavelength mixing of synchronized lasers has been shown to increase the spectral window of excitable fluorophores without the need for wavelength ***,most currently available dual output laser sources rely on the costly and complicated optical parametric generation *** this report,we detail a relatively simple and low cost diamond Raman laser pumped by a ytterbium fiber amplifier emitting at 1055 nm,which generates a first Stokes emission centered at 1240 nm with a pulse width of 100 *** two excitation wavelengths of 1055 and 1240 nm,along with the effective two-color excitation wavelength of 1140 nm,provide an almost complete coverage of fluorophores excitable within the range of 1000–1300 *** compared with 1055 nm excitation,two-color excitation at 1140 nm offers a 90%increase in signal for many far-red emitting fluorescent proteins(for example,tdKatushka2).We demonstrate multicolor imaging of tdKatushka2 and Hoechst 33342 via simultaneous two-color two-photon,and two-color three-photon microscopy in engineered 3D multicellular *** further discuss potential benefits and applications for two-color three-photon *** addition,we show that this laser system is capable of in vivo imaging in mouse cortex to nearly 1 mm in depth with two-color excitation.

关键词： microscopy nonlinear processes three-dimensional imaging ultrafast lasers

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Dynamic Gain-Clamped Amplifier with Backward-Injection of a Fabry-Perot Laser

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光学学报 2003年第S1期23卷 499-500页

作者： Chien-Hung yeh Chih-Yang chen Chien-Chung Lee Sien Chi Institute of Electro-Optical Engineering Chiao-Tung University 1001 Ta Hsueh Road Hsinchu Taiwan 300

We have been experimentally demonstrated an active control technique of dynamic gain-clamped spectra for theerbium-doped fiber amplifiers (EDFA's) by a backward-injected Fabry-Perot (F-P) laser into this EDFA. In addition, employing a short length erbium-doped fiber (EDF) that not cause any gain saturation for preamplification in front of this amplifier module, it can reduce the noise figure degradation and simultaneously achieve gain variation from 11.1 dB to 0.5 dB for 10 dB input power level change.

关键词： control technique fiber amplifiers noise figure input power

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Mechanics and mechanotransduction of tumorigenic cells

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医用生物力学 2013年第S1期28卷 1-2页

作者： Youhua Tan Junwei chen Arash Tajik yeh-chuin Poh Ning Wang School of Life Science and Technology Huazhong University of Science and Technology Department of Mechanical Science and Engineering University of Illinois at Urbana-Champaign

Despite significant progress in cancer research during the past decades,yet there are no major breakthroughs that can be translated into major benefits for the general public in terms of treatment or therapy for the complex neoplastic diseases,especially for the malignant solid *** depressing but indisputable fact leads to a call for new ideas to target tumor metastasis by editors of Nature Medicine[1].The real problems are that the fundamental issues of transformation and malignancy in vivo are poorly *** a recent review on cancer,

关键词： malignancy understood neoplastic metastasis poorly translated metastatic tumorigenesis invasion angiogenesis

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Block Decompositions and Applications of Generalized Reflexive Matrices

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Advances in Linear Algebra & Matrix Theory 2018年第3期8卷 122-133页

作者： hsin-Chu chen Department of Cyber-Physical Systems Clark Atlanta University Atlanta GA USA

Generalize reflexive matrices are a special class of matrices ?that have the relation where? and ?are some generalized reflection matrices. The nontrivial cases ( or ) of this class of matrices occur very often in many scientific and engineering applications. They are also a generalization of centrosymmetric matrices and reflexive matrices. The main purpose of this paper is to present block decomposition schemes for generalized reflexive matrices of various types and to obtain their decomposed explicit block-diagonal structures. The decompositions make use of unitary equivalence transformations and, therefore, preserve the singular values of the matrices. They lead to more efficient sequential computations and at the same time induce large-grain parallelism as a by-product, making themselves computationally attractive for large-scale applications. A numerical example is employed to show the usefulness of the developed explicit decompositions for decoupling linear least-square problems whose coefficient matrices are of this class into smaller and independent subproblems.

关键词： Generalized Reflexive Matrices Reflexive Matrices Centrosymmetric Matrices Generalized Simultaneous Diagonalization Simultaneous Diagonalization Linear Least-Square Problems

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The Chinese Yin-Yang Thinking in Antoni Tàpies’Artistic Creation

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Journal of Literature and Art Studies 2020年第9期10卷 815-820页

作者： Mei-hsin chen University of Navarra PamplonaSpain

The writings and artistic works of Antoni Tàpies(2009;2011)mirror the influences of the cosmic vision of the Chinese ***,numbers,and creative procedures related to this correlative thought prevail in his art.Tàpies integrated different iconological codes from the ancient Chinese thinking into his art to question the existential meaning of the universe and to express his thoughts on the cultural and socio-political controversies of his *** other words,the images,media,and techniques that he utilized for his works were extensions of his life experiences intertwined with various socio-historical facts and his personal feelings.

关键词： Antoni Tàpies theory of art aesthetics contemporary art yin-yang thinking Book of Changes

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Two-Level Block Decompositions for Solving Helmholtz Equation via Chebyshev Pseudo Spectral Method

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Journal of Modern Physics 2018年第9期9卷 1713-1723页

作者： hsin-Chu chen Department of Computer and Information Science Clark Atlanta University Atlanta GA USA

In this paper, we consider solving the Helmholtz equation in the Cartesian domain , subject to homogeneous Dirichlet boundary condition, discretized with the Chebyshev pseudo-spectral method. The main purpose of this paper is to present the formulation of a two-level decomposition scheme for decoupling the linear system obtained from the discretization into independent subsystems. This scheme takes advantage of the homogeneity property of the physical problem along one direction to reduce a 2D problem to several 1D problems via a block diagonalization approach and the reflexivity property along the second direction to decompose each of the 1D problems to two independent subproblems using a reflexive decomposition, effectively doubling the number of subproblems. Based on the special structure of the coefficient matrix of the linear system derived from the discretization and a reflexivity property of the second-order Chebyshev differentiation matrix, we show that the decomposed submatrices exhibits a similar property, enabling the system to be decomposed using reflexive decompositions. Explicit forms of the decomposed submatrices are derived. The decomposition not only yields more efficient algorithm but introduces coarse-grain parallelism. Furthermore, it preserves all eigenvalues of the original matrix.

关键词： Helmholtz Equation Chebyshev Pseudo-Spectral Method Chebyshev Differentiation Matrix Coarse-Grain Parallelism Reflexive Matrix

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Refeeding syndrome in Southeastern Taiwan:Our experience with 11 cases

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World Journal of Gastroenterology 2014年第30期20卷 10525-10530页

作者： Li-Ju chen Huan-Lin chen Ming-Jong Bair Chia-Hsien Wu I-Tsung Lin Yuan-Kai Lee cheng-hsin Chu Department of Nutrition Mackay Memorial Hospital Division of Gastroenterology Department of Internal MedicineMackay Memorial Hospital Department of Nursing Meiho University Department of Pharmacy and Graduate Institute of Pharmaceutical Technology Tajen University Department of Nutrition and Gastroenterology Mackay Memorial Hospital Mackay Junior College of Medicine Nursingand Management College

AIM: To present our experience with refeeding syndrome in southeastern Taiwan.

关键词： Refeeding syndrome Nutrition status Cachexia Hypophosphatemia Risk assessment

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Size-dependent dissociation of small cobalt clusters on ultrathin NaCI films

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Nano Research 2017年第5期10卷 1832-1839页

作者： Zhe Li hsin-Yi Tiffany chen Koen Schouteden Thomas Picot Arnaud Hillion Gianfranco Pacchioni Chris Van Haesendonck Ewald Janssens Peter Lievens Laboratory of Solid-State Physics and Magnetism KU Leuven BE-3001 Leuven Belgium Key Laboratory of Materials Modification by Laser Ion and Electron Beams Ministry of Education Dalian University of Technology Dalian 116024 China Department of Engineering and System Science "National Tsing Hua University" Hsinchu 30013 Taiwan China Dipartimen to di Scienza dei Materiali Universita di Milano-Bicocca 1-20125 Milano Italy

Mass-selected anionic cobalt clusters of two different sizes （Co2 and Co13） were deposited onto ultrathin NaC1 films grown on an Au（111） substrate. Using scanning tunneling microscopy experiments and density functional theory simulations, we show that the deposited Co2 cluster dissociates and that the resulting Co atoms dope the NaCI surface by substituting Na ions. In contrast, the larger Co13 cluster does not dissociate and remains stable on top of the NaC1 film. The size- dependent fragmentation of clusters is an important aspect in the understanding of the chemical interaction between size-selected small aggregates of atoms and supporting surfaces.

关键词： cobalt clusters mass selection size-dependentfragmentation scanning tunnelingmicroscopy density functional theory

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