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On-site rapid detection of multiple pesticide residues in tea leaves by lateral flow immunoassay

Journal of Pharmaceutical Analysis 2024年第2期14卷 276-283页

作者： Junxia Gao Tianyi zhang Yihua Fang Ying Zhao Mei Yang Li Zhao ye Li Jun Huang Guonian zhu Yirong Guo Institute of Pesticide and Environmental Toxicology Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang ProvinceMinistry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and InsectsZhejiang UniversityHangzhou310058China Tea Research Institute Chinese Academy of Agricultural SciencesKey Laboratory of Tea Biology and Resources UtilizationMinistry of AgricultureHangzhou310008China Shanghai Agricultural Technology Extension Service Center Shanghai201103China School of Biological and Chemical Engineering Zhejiang University of Science and TechnologyHangzhou311200China

The application of pesticides (mostly insecticides and fungicides) during the tea-planting process will undoubtedly increase the dietary risk associated with drinking tea. Thus, it is necessary to ascertain whether pesticide residues in tea products exceed the maximum residue limits. However, the complex matrices present in tea samples comprise a major challenge in the analytical detection of pesticide residues. In this study, nine types of lateral flow immunochromatographic strips (LFICSs) were developed to detect the pesticides of interest (fenpropathrin, chlorpyrifos, imidacloprid, thiamethoxam, acetamiprid, carbendazim, chlorothalonil, pyraclostrobin, and iprodione). To reduce the interference of tea substrates on the assay sensitivity, the pretreatment conditions for tea samples, including the extraction solvent, extraction time, and purification agent, were optimized for the simultaneous detection of these pesticides. The entire testing procedure (including pretreatment and detection) could be completed within 30 min. The detected results of authentic tea samples were confirmed by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), which suggest that the LFICS coupled with sample rapid pretreatment can be used for on-site rapid screening of the target pesticide in tea products prior to their market release.

关键词： Lateral flow immunoassay Rapid detection Pesticide multi-residue Tea matrix Sample rapid pretreatment

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Acute suppurative terminal cholangitis:Clinical characteristics of a new subtype of acute cholangitis

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 293-299页

作者： Rong-Tao zhu ye Li Chi-Xian zhang Wei-Jie Wang Ruo-Peng Liang Jian Li Kai Bai Yu-Ling Sun Department of Hepatobiliary and Pancreatic Surgery the First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Zhengzhou Key Laboratory of Hepatobiliary and Pancreatic Diseases Zhengzhou 450052China Institute of Hepatobiliary and Pancreatic Diseases Zhengzhou UniversityZhengzhou 450052China Department of Pathology the First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China

Background:Acute suppurative terminal cholangitis(ASTC)is rarer than acute obstructive cholangitis and is not well *** explore this subtype of acute cholangitis,we described our clinical experience with ***:We performed a retrospective review of patients with ASTC admitted to our center from September 2014 to August *** analyzed their clinical characteristics,including etiology,clinical manifestations,imaging features,treatment and ***:A total of 32 ASTC patients were included in the *** majority of the patients had a history of biliary operations,and clinical manifestations were occult and *** positive rate of bacterial culture was 46.9%.All the patients had typical imaging features on computed tomography and magnetic resonance *** with effective antibiotics was provided as soon as diagnosis was *** treatment,most patients had a good *** levels of total bilirubin,aspartate aminotransferase,procalcitonin and gamma-glutamyltransferase were the characteristics of critically ill patients and were associated with relatively poor ***:Our results demonstrated that ASTC should be recognized as a new subtype of acute cholangitis,and that earlier diagnosis and more personalized treatments are needed.

关键词： Acute suppurative terminal cholangitis Acute cholangitis Gram-negative bacterial infections Diagnosis Treatment

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Learning accurate template matching with differentiable coarseto-fine correspondence refinement

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Computational Visual Media 2024年第2期10卷 309-330页

作者： Zhirui Gao Renjiao Yi Zheng Qin Yunfan ye Chenyang zhu Kai Xu College of Computer National University of Defense TechnologyChangsha 410073China

Template matching is a fundamental task in computer vision and has been studied for *** plays an essential role in manufacturing industry for estimating the poses of different parts,facilitating downstream tasks such as robotic *** methods fail when the template and source images have different modalities,cluttered backgrounds,or weak *** also rarely consider geometric transformations via homographies,which commonly exist even for planar industrial *** tackle the challenges,we propose an accurate template matching method based on differentiable coarse-tofine correspondence *** use an edge-aware module to overcome the domain gap between the mask template and the grayscale image,allowing robust *** initial warp is estimated using coarse correspondences based on novel structure-aware information provided by *** initial alignment is passed to a refinement network using references and aligned images to obtain sub-pixel level correspondences which are used to give the final geometric *** evaluation shows that our method to be significantly better than state-of-the-art methods and baselines,providing good generalization ability and visually plausible results even on unseen real data.

关键词： template matching differentiable homography structure-awareness transformers

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Effect of yttrium and manganese addition on catalytic soot combustion activity and anti-high-temperature stability of CeO_(2) catalyst

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Journal of Rare Earths 2024年第2期42卷 334-344,I0004页

作者： Yi zhu Xingyu Liu Wei Shi Jia Li Changbing ye Ruimei Fang Huifeng zhu Shanhu Chen Li Lan College of Chemistry Biology and Environment Yuxi Normal UniversityYuxi 653100China Institute of Biology and Environmental Engineering Yuxi Normal UniversityYuxi 653100China College of Environment and Resources Chongqing Technology and Business UniversityChongqing 400067China College of Chemistry and Chemical Engineering Jiangxi Science and Technology Normal UniversityNanchang 330013China College of Materials and Mechatronics Jiangxi Science and Technology Normal UniversityNanchang 330013China

In order to analyze the influence of the addition of yttrium and manganese on the soot combustion performance and high temperature stability of CeO_(2) catalyst,a series of Y/Mn-modified CeO_(2) catalysts were *** effects of structural properties,textural properties,oxygen vacancies,Ce^(3+),surface adsorbed oxygen species,reduction properties and desorption properties of oxygen species on the activity were analyzed by various characterization *** results of the activity test show that the addition of manganese is beneficial to enhancement of the activity,while the addition of yttrium increases the amount of reactive oxygen species,but decreases the *** aging at 700℃,the activity of the CeMn catalyst decreases most sharply,while the catalytic activity of the CeY catalyst can be maintained to a certain ***,the addition of yttrium and manganese at the same time can stabilize the *** fundamental reason is that yttrium and manganese move to the surface of the solid solution after aging,which increases the reduction performance of the catalyst,thus contributing to the increase of *** the activity of CeYMn catalyst decreases after aging at 800℃,it is still higher than that of other catalysts aged at 700℃.

关键词： CeO_(2)catalyst Soot catalytic combustion Diesel pollution control Rare earths High temperature stability Low temperature reduction performance

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Structural phase transition in a new organic-inorganic hybrid post-perovskite:(N,N-dimethylpyrrolidinium)[Mn(N(CN)_(2))_(3)]

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Chinese Journal of Structural Chemistry 2024年第6期43卷 40-44页

作者： Le ye Wei-Xiong zhang MOE Key Laboratory of Bioinorganic and Synthetic Chemistry School of ChemistryIGCMESun Yat-Sen UniversityGuangzhou510275China

In the realm of molecular phase transition research,particularly for applications in sensors,data storage and switching technologies,the role of organic-inorganic hybrid perovskite materials has been increasingly recognized for their significant ***,hybrid post-perovskites,as a critical subclass of perovskites,have not been thoroughly studied and mainly limit in the instances based on polyatomic bridging agents like dicyanamide(dca^(-))and non-cyclic organic ***,a polar cyclic quaternary ammonium cation,N,N-dimethylpyrrolidinium(DMP^(+)),was used to assemble a new hybrid post-perovskite,(DMP)[Mn(dca)_(3)](1),which undergoes a phase transition from orthorhombic Bmmb to monoclinic P2_(1)/n space group at 249 *** employing multiple techniques such as differential scanning calorimetry,variable-temperature single-crystal X-ray analysis,dielectric measurements,and Hirshfeld surface analysis,we disclosed the role of polar cyclic quaternary ammonium DMP^(+)in elevating the phase-transition temperature by 48 K,generating significant dielectric switching effect and facilitating interlayer sliding of inorganic framework.

关键词： Structural phase transitions Dielectric switching Organic-inorganic hybrid crystals Post-perovskites

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Netrin-1 signaling pathway mechanisms in neurodegenerative diseases

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Neural Regeneration Research 2025年第4期20卷 960-972页

作者： Kedong zhu Hualong Wang Keqiang ye Guiqin Chen Zhaohui zhang Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina Department of Neurology The First Hospital of Hebei Medical UniversityBrain Aging and Cognitive Neuroscience Laboratory of Heibei ProvinceShijiazhuangHebei ProvinceChina Faculty of Life and Health Sciences Shenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

Netrin-1 and its receptors play crucial roles in inducing axonal growth and neuronal migration during neuronal *** profound impacts then extend into adulthood to encompass the maintenance of neuronal survival and synaptic *** amounts of evidence highlight several key points:(1)Diminished Netrin-1 levels exacerbate pathological progression in animal models of Alzheimer’s disease and Parkinson’s disease,and potentially,similar alterations occur in humans.(2)Genetic mutations of Netrin-1 receptors increase an individuals’susceptibility to neurodegenerative disorders.(3)Therapeutic approaches targeting Netrin-1 and its receptors offer the benefits of enhancing memory and motor function.(4)Netrin-1 and its receptors show genetic and epigenetic alterations in a variety of *** findings provide compelling evidence that Netrin-1 and its receptors are crucial targets in neurodegenerative *** a comprehensive review of Netrin-1 signaling pathways,our objective is to uncover potential therapeutic avenues for neurodegenerative disorders.

关键词： Alzheimer’s disease axon guidance colorectal cancer Netrin-1 receptors Netrin-1 signaling pathways Netrin-1 neurodegenerative diseases neuron survival Parkinson’s disease UNC5C

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An Algorithm of Deformation Image Correction Based on Spatial Mapping

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Chinese Journal of Electronics 2024年第5期33卷 1326-1336页

作者： Xiangyu DENG Aijia zhang Jinhong ye College of Physics and Electronic Engineering Northwest Normal University

The original image undergoes geometric deformation in terms of position, shape, size, and orientation due to the shooting angle or capturing process during image acquisition. This leads to inconveniences and significant challenges in various image processing fields such as image fusion, denoising, recognition, and segmentation. To enhance the processing ability and recognition accuracy of deformation images, an adaptive algorithm for correcting image deformities is proposed for quadrilaterals and triangles. Firstly, the deformation image undergoes preprocessing, and the contour of the image edge is extracted. Then, discrete points on the image edge are identified to accurately locate the edges. Finally, the deformation of the quadrilateral or triangle is transformed into a standard rectangular or equilateral triangular image using the proposed three-dimensional homography transformation algorithm. This effectively completes the conversion from an irregular image to a regular image in an adaptive manner. Numerous experiments demonstrate that the proposed algorithm surpasses traditional methods like Hough transform and Radon *** improves the effectiveness of correcting deformation in images, effectively addresses the issue of geometric deformation, and provides a new technical method for processing deformation images.

关键词： Image preprocessing Image vertex positioning Three-dimensional space Homography transformation Image correction Image preprocessing Image vertex positioning Three-dimensional space Homography transformation Image correction DISTORTION

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Polyethylene interfacial dielectric layer for organic semiconductor single crystal based field-effect transistors

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Chinese Chemical Letters 2024年第4期35卷 431-435页

作者： Min Chen Boyu Peng Xuyun Guo ye zhu Hanying Li Department of Polymer Science and Engineering MOE Key Laboratory of Macromolecular Synthesis and FunctionalizationInternational Research Center for X PolymersShanxi-Zheda Institute of Advanced Materials and Chemical EngineeringZhejiang UniversityHangzhou 310027China Department of Applied Physics Research Institute for Smart EnergyThe Hong Kong Polytechnic UniversityHong Kong 999077China

Organic semiconductor single crystals(OSSCs) have shown their promising potential in high-performance organic field-effect transistors(OFETs). The interfacial dielectric layers are critical in these OFETs as they not only govern the key semiconductor/dielectric interface quality but also determine the growth of OSSCs by their wetting properties. However, reported interfacial dielectric layers either need rigorous preparation processes, rely on certain surface chemistry reactions, or exhibit poor solvent resistance, which limits their applications in low-cost, large-area, monolithic fabrication of OSSC-based OFETs. In this work, polyethylene(PE) thin films and lamellar single crystals are utilized as the interfacial dielectric layers, providing solvent resistive but wettable surfaces that facilitate the crystallization of 6,13-bis(tri-isopropylsilylethynyl)pentacene(TIPS-PEN) and 6,13-bis(triisopropylsilylethynyl)-5,7,12,14-tetraazapentacene(TIPS-TAP). As evidenced by the presence of ambipolar behavior in TIPS-PEN single crystals and the high electron mobility(2.3 ± 0.34 cm^(2)V^(-1)s^(-1)) in TIPS-TAP single crystals, a general improvement on electron transport with PE interfacial dielectric layers is revealed, which likely associates with the chemically inertness of the saturated C-H bonds. With the advantages in both processing and device operation, the PE interfacial dielectric layer potentially offers a monolithic way for the enhancement of electron transport in solution-processed OSSC-based OFETs.

关键词： Polyethylene Interfacial dielectric layer Organic semiconductor Single crystal Organic field-effect transistors

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Dynamic compliance of energy-saving legged elastic parallel joints for quadruped robots:design and realization

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Frontiers of Mechanical Engineering 2024年第2期19卷 45-58页

作者： Yaguang zhu Minghuan zhang Xiaoyu zhang Haipeng QIN Key Laboratory of Road Construction Technology and Equipment of Ministry of Education School of Engineering MachineryChang’an UniversityXi’an 710064China State Key Laboratory of Robotics and Systems Harbin Institute of TechnologyHarbin 150001China

Achieving dynamic compliance for energy-efficient legged robot motion is a longstanding *** recent predictive control methods based on single-rigid-body models can generate dynamic motion,they all assume infinite energy,making them unsuitable for prolonged robot *** this issue necessitates a mechanical structure with energy storage and a dynamic control strategy that incorporates feedback to ensure *** work draws inspiration from the efficiency of bio-inspired muscle–tendon networks and proposes a controllable torsion spring leg *** design integrates a spring-loaded inverted pendulum model and adopts feedback delays and yield springs to enhance the delay effects.A leg control model that incorporates motor loads is developed to validate the response and dynamic performance of a leg with elastic *** model provides torque to the knee joint,effectively reducing the robot’s energy consumption through active or passive control *** benefits of the proposed approach in agile maneuvering of quadruped robot legs in a realistic scenario are demonstrated to validate the dynamic motion performance of the leg with elastic joints with the advantage of energy-efficient legs.

关键词： dynamic responsiveness energy dissipation legged locomotion parallel joints quadruped robot

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Comprehensive Relation Modelling for Image Paragraph Generation

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Machine Intelligence Research 2024年第2期21卷 369-382页

作者： Xianglu zhu zhang zhang Wei Wang Zilei Wang Automation Department University of Science and Technology of ChinaHefei 230027China Center for Research on Intelligent Perception and Computing National Laboratory of Pattern RecognitionInstitute of AutomationChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100864China

Image paragraph generation aims to generate a long description composed of multiple sentences,which is different from traditional image captioning containing only one *** of previous methods are dedicated to extracting rich features from image regions,and ignore modelling the visual *** this paper,we propose a novel method to generate a paragraph by modelling visual relationships ***,we parse an image into a scene graph,where each node represents a specific object and each edge denotes the relationship between two ***,we enrich the object features by implicitly encoding visual relationships through a graph convolutional network(GCN).We further explore high-order relations between different relation features using another graph convolutional *** addition,we obtain the linguistic features by projecting the predicted object labels and their relationships into a semantic embedding *** these features,we present an attention-based topic generation network to select relevant features and produce a set of topic vectors,which are then utilized to generate multiple *** evaluate the proposed method on the Stanford image-paragraph dataset which is currently the only available dataset for image paragraph generation,and our method achieves competitive performance in comparison with other state-of-the-art(SOTA)methods.

关键词： Image paragraph generation visual relationship scene graph graph convolutional network(GCN) long short-term memory

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