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Seroepidemiology of hepatitis B virus infection and impact of vaccination

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World Journal of Gastroenterology 2015年第25期21卷 7842-7850页

AIM: To investigate hepatitis B virus(HBV) prevalence in the general population in ***: A total of 148931 individuals were investigated by multistage random sampling in Eastern China. Data were collected on demographics and hepatitis B vaccination history, and serum was tested for hepatitis B surface antigen(HBs Ag) by ELISA. RESULTS: A total of 11469 participants(7.70%, 95%CI: 7.57%-7.84%) were positive for HBs Ag. HBs Ag prevalence was 0.77% among children years old but increased progressively from adolescents(1.40%-2.55%) to adults(5.69%-11.22%). A decrease in HBs Ag prevalence was strongly associated with vaccination and familial history of HBV among both children and adult groups. Meanwhile, HBs Ag risk in adults was associated with invasive testing and sharing needles. The HBV immunization rate among participants aged years was 93.30%(95%CI: 93.01%-93.58%). Significant difference in HBs Ag prevalence appeared between vaccinated and unvaccinated participants(3.59% vs 10.22%). CONCLUSION: Although the national goal of HBs Ag prevalence years old has been reached, immunization programs should be maintained to prevent resurgence.

关键词： Epidemiological study Familial history Hepatitis B surface antigen Immunization Generalpopulation

Langmuir-Blodgett Films of Hexamolybdate and Naphthylamine Prepared by Two Different Approaches: Synthesis, Characterization, and Materials Properties

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Langmuir-Blodgett Films of Hexamolybdate and Naphthylamine P...

Netrin-1 signaling pathway mechanisms in neurodegenerative diseases

中国化学会第五届全国多酸化学学术研讨会

作者： Qian Liu Jing Ni Zhou Zhou ye-fei zhu Shi-Zhong Liu Fa-Bao Li Li Liu School of Chemistry and Chemical Engineering Hubei University

＜正＞Two novel covalently-linked organic-inorganic hybrid compounds[（n-C4H9）4N]2[Mo6O18（N-（2-Np））]（NA-Mo6） and [（n-C4H9）4N]2[Mo6O17（N-（1-Np））2]（NA2-Mo6）（2-Np=2-naphthyl;1-Np=1-naphthyl） have been pr... 详细信息

关键词： crystal structure hexamolybdate naphthylamine Langmuir-Blodgett film organic-inorganic hybrid

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Neural Regeneration Research 2025年第4期20卷 960-972页

作者： Kedong zhu Hualong Wang Keqiang ye Guiqin Chen Zhaohui Zhang Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina Department of Neurology The First Hospital of Hebei Medical UniversityBrain Aging and Cognitive Neuroscience Laboratory of Heibei ProvinceShijiazhuangHebei ProvinceChina Faculty of Life and Health Sciences Shenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

Netrin-1 and its receptors play crucial roles in inducing axonal growth and neuronal migration during neuronal *** profound impacts then extend into adulthood to encompass the maintenance of neuronal survival and synaptic *** amounts of evidence highlight several key points:(1)Diminished Netrin-1 levels exacerbate pathological progression in animal models of Alzheimer’s disease and Parkinson’s disease,and potentially,similar alterations occur in humans.(2)Genetic mutations of Netrin-1 receptors increase an individuals’susceptibility to neurodegenerative disorders.(3)Therapeutic approaches targeting Netrin-1 and its receptors offer the benefits of enhancing memory and motor function.(4)Netrin-1 and its receptors show genetic and epigenetic alterations in a variety of *** findings provide compelling evidence that Netrin-1 and its receptors are crucial targets in neurodegenerative *** a comprehensive review of Netrin-1 signaling pathways,our objective is to uncover potential therapeutic avenues for neurodegenerative disorders.

关键词： Alzheimer’s disease axon guidance colorectal cancer Netrin-1 receptors Netrin-1 signaling pathways Netrin-1 neurodegenerative diseases neuron survival Parkinson’s disease UNC5C

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Modification of Maxwell model for conductivity prediction of carbon nanotubes-filled polymer composites with tunneling effect

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 25-36页

作者： Jue zhu Longyuan LI Ningtao zhu Zhejiang Provincial Engineering Research Center for the Safety of Pressure Vessel and Pipeline Key Laboratory of Impact and Safety Engineering (Ningbo University) Ministry of Education School of Engineering Computing and Mathematics University of Plymouth Xi'an Zhanshi Testing & Engineering Co.Ltd.

Carbon nanotubes(CNTs) have garnered great attention in recent years due to their outstanding electrical, thermal, and mechanical properties. The incorporation of small amounts of CNTs in polymers can substantially improve the sensitivity of the polymer's electrical conductivity. This paper presents a modified Maxwell model to evaluate the electrical conductivity of CNTs-filled polymer composites by introducing a transition zone to account for the tunneling effect. In this modified Maxwell model, the CNTs-filled polymer composite is modeled as a three-phase composite, consisting of a matrix(polymer), inclusions(CNTs), and a transition zone(tunneling zone). The effective electrical conductivity(EEC) of the composite is calculated based on the volume fractions and electrical conductivities of the matrix, inclusions, and transition zone. The model's validity is confirmed through the use of available test data, which demonstrates its capability to accurately capture the nonlinear conductivity behavior observed in CNTs-polymer composites. This study offers valuable insights into the design of high-performance conductive polymer nanocomposites, and enhances the understanding of electrical conduction mechanisms in CNT-dispersed polymer composites.

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Impacts of the annual cycle of background SST in the tropical Pacific on the phase and amplitude of ENSO

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 12-17页

作者： Song Jiang Congwen zhu Ning Jiang State Key Laboratory of Severe Weather(LASW) Chinese Academy of Meteorological SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina

The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of *** on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bjerknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual *** magnitude of the SST anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity *** reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SST on ENSO,which possibly carries important implications for forecasting ENSO.

关键词： Annual cycle SST anomaly Antisymmetric mode ENSO

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Satellite remote sensing reveals overwhelming recovery of forest from disturbances in Asia

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 46-51页

作者： Yiying zhu Hesong Wang Anzhi Zhang School of Ecology and Nature Conservation Beijing Forestry UniversityBeijingChina Key Laboratory of Regional Climate and Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina College of Forestry and Landscape Architecture Xinjiang Agricultural UniversityUrumqiChina

Forest ecosystems play key roles in mitigating human-induced climate change through enhanced carbon uptake;however,frequently occurring climate extremes and human activities have considerably threatened the stability of *** the same time,detailed accounts of disturbances and forest responses are not yet well quantified in *** study employed the Breaks For Additive Seasonal and Trend method-an abrupt-change detection method-to analyze the Enhanced Vegetation Index time series in East Asia,South Asia,and Southeast *** approach allowed us to detect forest disturbance and quantify the resilience after *** showed that 20%of forests experienced disturbance with an increasing trend from 2000 to 2022,and Southeast Asian countries were more severely affected by ***,95%of forests had robust resilience and could recover from disturbance within a few *** resilience of forests suffering from greater magnitude of disturbance tended to be stronger than forests with lower disturbance *** summary,this study investigated the resilience of forests across the low and middle latitudes of Asia over the past two *** authors found that most forests exhibited good resilience after disturbance and about two-thirds had recovered to a better state in *** findings of this study underscore the complex relationship between disturbance and resilience,contributing to comprehension of forest resilience through satellite remote sensing.

关键词： Forest ecosystem Enhanced vegetation index Breaks for additive seasonal and trend method Disturbance Resilience

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In vivo imaging of macrophage activity in the early-stage abdominal aortic dissection

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In vivo imaging of macrophage activity in the early-stage ab...

第十三次全国心血管病学术会议

作者： YAO Yu-yu,WANG Yuan-yuan,Zhang Yi,LI ye-fei,SHENG zhu-long, WENG Song,MA Gen-shan,LIU Nai-feng,FANG Fang,TENG Gao-jun *Department of Cardiology,Zhongda Hospital,Medical School of Southeast University,Nanjing,Jiangsu 210009,China

Objective AngiotensinⅡ(AngⅡ) has been reported to accelerate atherosclerosis and induce aortic aneurysm in hyperlipidemic apolipoprotein E knock-out(apoE

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基于肠道菌群的视角探讨中医药治疗肝纤维化

世界华人消化杂志 2023年第21期31卷 889-895页

作者：吕生霞王章程朱颖贾玲娟朱梦陶凌辉王一科朱飞叶张永生浙江中医药大学基础医学院浙江省杭州市310053 浙江中医药大学中医药科学院浙江省杭州市310053

肝纤维化是各种慢性肝病的关键阶段,其发生发展与肠道微生物菌群失调密切相关.在治疗方面,目前尚缺乏理想的化学药物,然而中药在该领域显示出独特的临床疗效.近年来中医药在肠道菌群调节方面的研究备受学术界关注,中药复方抗肝纤维化有... 详细信息

肝纤维化是各种慢性肝病的关键阶段,其发生发展与肠道微生物菌群失调密切相关.在治疗方面,目前尚缺乏理想的化学药物,然而中药在该领域显示出独特的临床疗效.近年来中医药在肠道菌群调节方面的研究备受学术界关注,中药复方抗肝纤维化有效成分的首要作用靶点可能是肠道菌群,或者通过肠道菌群媒介、菌群特征性重构发挥生物学效应.“肠肝轴”视角下,中医药通过“肝脾同治”调节肠道菌群,与抗肝纤维化紧密相连.本文立足“肠肝轴”,以调和肝脾为落脚点,讨论中药及其活性成分通过调节肠道菌群从而发挥其抗肝纤维化作用,为中医药抗肝纤维化提供新的研究视角.

关键词：肝纤维化肠道菌群中医药肠肝轴调和肝脾

“Slope-adsorption & plateau-pore filling” mechanism unlocking the potential of hard carbon anodes for “fast-charging & large-sized”batteries

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Science China Materials 2025年第1期 309-311页

作者： Tian Liang Xiaoming zhu Hubei Key Laboratory of Radiation Chemistry and Functional Materials School of Nuclear Technology and Chemistry & Biology Hubei University of Science and Technology

To date, there has been no report on fast-charging and Ahlevel sodium-ion batteries (SIBs) by utilizing thick hard carbon anodes that demonstrate prolonged cycling life and high areal capacity at high rates. Further, the relationship among the complex structure of hard carbon, storage mechanism, and fastcharging performance in alkali-metal ion batteries has been a subject of ongoing debate [1,2].

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