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Understanding of Five Grains for YANG:a way to straighten Asians’dietary structure

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Food and Health 2024年第3期6卷 18-19页

作者： Jing-Chao Ma Cai-Jie Zhang Wen-Li zhao ye zhao* Intelligent Imaging College He UniversityShenyang 110163China.2 Liver CenterSaga University HospitalSaga University 849-8501Japan.3 Department of Public HealthInternational CollegeKrirk UniversityBangkok 10220Thailand.

According to the general opinion,grains should occupy the largest amount of human food each day,but this grain-based eating habit does not allow human life to be extended.Grains are high in carbohydrates and five commonly recognized plant hormones,namely auxin,gibberellin,cytokinin,abscisic acid,and ethylene.Through in-depth analysis of ancient books,it was found that five grains for support:support is a restriction,and it means the essence,which means that grains should be eaten less,and it is the essence of the least daily intake.To correctly understand the Chinese dietary concept of"five grains for support"is the basis for improving Asian dietary health and promoting Asian human health.

关键词： Grains Hormones Carbohydrates Eating habits

Transforming liquid flow fuel cells to controllable reactors for highlyefficient oxidation of 5-hydroxymethylfurfural to 2, 5-furandicarboxylic acid at low temperature

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Journal of Energy Chemistry 2024年第3期90卷 621-631,I0014页

作者： ye Qiang Xi Liu Denghao Ouyang zhao Jiang Xuebing zhao Key Laboratory of Industrial Biocatalysis Ministry of EducationTsinghua UniversityBeijing 100084China Institute of Applied Chemistry Department of Chemical EngineeringTsinghua UniversityBeijing 100084China School of Chemical Engineering and Technology Xi'an Jiaotong UniversityXi'an 710049ShaanxiChina

Highly-efficient oxidation of 5-hydroxymethylfurtural(HMF) to 2,5-furandicarboxylic acid(FDCA) at low temperature with air as the oxidant is still challenging.Herein,inspired by the respirato ry electron transport chain(ETC) of living cells mediated by electron carriers,we constructed artificial ETCs and transformed liquid flow fuel cells(LFFCs) to flexible reactors for efficient oxidation of HMF to produce FDCA under mild conditions.This LFFC reactor employed an electrodeposition modified nickel foam as an anode to promote HMF oxidation and(VO_(2))_(2)SO_(4) as a cathode electron carrier to facilitate the electron transfer to air.The reaction rate could be easily controlled by selecting the anode catalyst,adjusting the external loading and changing the cathodic electron carrier or oxidants.A maximal power density of 44.9 mW cm^(-2) at room temperature was achieved,while for FDCA production,short-circuit condition was preferred to achieve quick transfer of electrons.For a single batch operation with 0.1 M initial HMF,FDCA yield reached 97.1%.By fed-batch operation,FDCA concentration reached 144.5 g L^(-1) with a total yield of 96%.Ni^(2+)/Ni^(3+) redox couple was the active species mediating the electron transfer,while both experimental and DFT calculation results indicated that HMFCA pathway was the preferred reaction mechanism.

关键词： 5-Hydroxymethylfurfural 2 5-Furandicarboxylic acid Electrodeposition Electron transport chain Liquid flow fuel cell

Rotor cross-tilt optimization for yaw control improvement of multi-rotor eVTOL aircraft

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Chinese Journal of Aeronautics 2024年第3期37卷 153-167页

作者： Xufei YAN ye YUAN Yanqin zhao Renliang CHEN Zhejiang Lab Hangzhou 311100China Department of Aerospace Engineering Swansea UniversitySwanseaWales SA28PPUK National Key Laboratory of Rotorcraft Aeromechanics Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Manned multi-rotor electric Vertical Takeoff and Landing(eVTOL)aircraft is prone to actuator saturation due to its weak yaw control efficiency.To address this inherent problem,a rotor cross-tilt configuration is applied in this paper,with an optimization method proposed to improve the overall control efficiency of the vehicle.First,a flight dynamics model of a 500-kg manned multi-rotor eVTOL aircraft is established.The accuracy of the co-axial rotor model is verified using a single arm test bench,and the accuracy of the flight dynamics model is verified by the flight test data.Then,an optimization method is designed based on the flight dynamics model to calculate an optimal rotor cross-tilt mounting angle,which not only improves the yaw control efficiency,but also basically maintains the efficiency of other control channels.The ideal rotor cross-tilt mounting angle for the prototype is determined by comprehensively considering the optimal results with different payloads,forward flight speeds,and rotor mounting angle errors.Finally,the feasibility of the rotor cross-tilt mounting angle is proved by analyzing the control derivatives of the flight dynamics model,the test data of a ground three Degree-of-Freedom(3DOF)platform,and the actual flight data of the prototype.The results show that a fixed rotor cross-tilt mounting angle can achieve ideal yaw control effectiveness,improving yaw angle tracking and hold ability,increasing endurance time,and achieving good yaw control performance with different payloads and forward speeds.

关键词： Multi-rotor eVTOL Control efficiency Flight dynamics model Cross-tilt optimization Endurance time

Ergothioneine and its congeners:anti-ageing mechanisms and pharmacophore

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Protein & Cell 2024年第3期15卷 191-206页

作者： Li Chen Liping Zhang Xujun ye Zixin Deng Changming zhao Department of Geriatrics Zhongnan Hospital of Wuhan UniversityWuhan UniversityWuhan 430072China Key Laboratory of Combinatory Biosynthesis and Drug Discovery School of Pharmaceutical SciencesMinistry of EducationWuhan UniversityWuhan 430072China tThese authors contributed equally.

Ergothioneine,Ovothiol,and Selenoneine are sulfur/selenium-containing histidine-derived natural products widely distributed across different organisms.They exhibit significant antioxidant properties,making them as potential lead compounds for promoting health.Increasing evidence suggests that Ergothioneine is positively correlated with healthy ageing and longevity.The mechanisms underlying Ergothioneine's regulation of the ageing process at cellular and molecular levels are beginning to be understood.In this review,we provide an in-depth and extensive coverage of the anti-ageing studies on Ergothioneine and discuss its possible intracellular targeting pathways.In addition,we highlight the recent efforts in elucidating the biosynthetic details for Ergothioneine,Ovothiol,and Selenoneine,with a particular focus on the study of their pharmacophore-forming enzymology.

关键词： Ergothioneine antioxidant anti-ageing longevity biosynthesis enzymology

HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies

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Genes & Diseases 2024年第1期11卷 234-251页

作者： Yan zhao Cheng Xing Yating Deng Can ye Hongling Peng Department of Hematology The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China Hunan Key Laboratory of Tumor Models and Individualized Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China Hunan Engineering Research Center of Cell Immunotherapy for Hematopoietic Malignancies The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China

The hypoxic microenvironment is an essential characteristic of most malignant tu-mors.Notably,hypoxia-inducible factor-1 alpha(HIF-1a)is a key regulatory factor of cellular adaptation to hypoxia,and many critical pathways are correlated with the biological activity of organisms via HIF-1a.In the intra-tumoral hypoxic environment,HIF-1αis highly expressed and contributes to the malignant progression of tumors,which in turn results in a poor prog-nosis in patients.Recently,it has been indicated that HiF-1αinvolves in various critical pro-cesses of life events and tumor development via regulating the expression of HiF-1a target genes,such as cell proliferation and apoptosis,angiogenesis,glucose metabolism,immune response,therapeutic resistance,etc.Apart from solid tumors,accumulating evidence has re-vealed that HiF-1αis also closely associated with the development and progression of hemato-logical malignancies,such as leukemia,lymphoma,and multiple myeloma.Targeted inhibition of HiF-1a can facilitate an increased sensitivity of patients with malignancies to relevant ther-apeutic agents.In the review,we elaborated on the basic structure and biological functions of HIF-1a and summarized their current role in various malignancies.It is expected that they will have future potential fortargeted therapy.

关键词： Angiogenesis Hematological malignancies Hypoxia-inducible factor-1 alpha(HIF-1α) Immune escape Targeted therapy

Emerging interactively stretchable electronics with optical and electrical dual-signal feedbacks based on structural color materials

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Nano Research 2024年第3期17卷 1837-1855页

作者： Jialin Wang Kai zhao Changqing ye Yanlin Song School of Materials Science and Engineering Suzhou University of Science and TechnologySuzhou 215009China Key Laboratory of Green Printing Institute of ChemistryChinese Academy of SciencesBeijing 100190China

The booming development of wearable devices has aroused increasing interests in flexible and stretchable devices.With mechanosensory functionality,these devices are highly desirable on account of their wide range of applications in electronic skin,personal healthcare,human–machine interfaces and beyond.However,they are mostly limited by single electrical signal feedback,restricting their diverse applications in visualized mechanical sensing.Inspired by the mechanochromism of structural color materials,interactively stretchable electronics with optical and electrical dual-signal feedbacks are recently emerged as novel sensory platforms,by combining both of their sensing mechanisms and characteristics.Herein,recent studies on interactively stretchable electronics based on structural color materials are reviewed.Following a brief introduction of their basic components(i.e.,stretchable electronics and mechanochromic structural color materials),two types of interactively stretchable electronics with respect to the nanostructures of mechanochromic materials are outlined,focusing primarily on their design considerations and fabrication strategies.Finally,the main challenges and future perspectives of these emerging devices are discussed.

关键词： stretchable electronics structural color materials interactive sensing mechanochromism dual-signal feedbacks

Clarification of the dispersion mechanism of cathode slurry of lithium-ion battery under effects of both poly vinylidene fluoride/carbon black ratio and mixing time

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Particuology 2024年第5期88卷 116-127页

作者： Zhilong Wang Zhenzhen zhao ye Yang An Zhang Xiayi Liu Tong zhao Yahui Cui School of Mechanical and Precision Instrument Engineering Xi'an University of TechnologyXi'an 710048China

This paper presents the effects of both poly vinylidene fluoride(PVDF)/carbon black(CB)ratio(m PVDF:m CB)and mixing time t on the dispersion mechanism of the cathode slurry of lithium-ion battery(LIB).The dispersion mechanism is deduced from the electrochemical,morphological and rheological properties of the cathode slurry by using electrical impedance spectroscopy(EIS),scanning electron microscopy and rheology methods,respectively.From the perspective of EIS method,static simulation models are established in the COMSOL Multiphysics software;meanwhile,the simulated results are used to verify the correctness of the electrochemical properties of the cathode slurry.As a result,the following conclusions are able to be obtained.Firstly,in the case of the mass ratio m PVDF:m CB=5:10,LiCoO2 particles are completely coated by the mixture of CB and PVDF to form a stable polymer gel structure.Higher or lower m PVDF:m CB leads to the larger impedance and worse dispersion status for the cathode slurry.Secondly,when t=6 min,a good gel-like conductive network structure is formed by coating the thinner evenly dispersed CB–PVDF double layer around LiCoO2 particles.Finally,a strategy regarding to both m PVDF:m CB and t in experimental scale is proposed,which has the capability of improving the performance of LIB.

关键词： Cathode slurry Dispersion mechanism Lithium-ion battery(LIB)

The Extension Dimension of Subcategories and Recollements of Abelian Categories

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Acta Mathematica Sinica,English Series 2024年第4期40卷 1042-1058页

作者： Xin MA ye Yang PENG zhao Yong HUANG College of Science Henan University of EngineeringZhengzhou 451191P.R.China Department of Mathematics Nanjing UniversityNanjing 210093P.R.China

We investigate the behavior of the extension dimension of subcategories of abelian categories under recollements.LetΛ',Λ,Λ"be art in algebras such that(modΛ',mod A,modΛ")is a recollement,and let D'and D"be subcategories of modΛand modΛ"respectively.For any n,m≥0,under some conditions,we get dimΩ^(k)(D)≤dimΩ^(n)(D')+dimΩ^(m)(D")+1,where k=max{m,n}and D is the subcategory of modΛglued by D'and D";moreover,we give a sufficient condition such that the converse inequality holds true.As applications,some results for Igusa-Todorov subcategories and syzygy finite sub categories are obtained.

关键词： Recollements extension dimension Igusa–Todorov subcategories syzygy finite subcategories

Preparation and properties of Ti_(3)SiC(2) -based corrosion mitigation coatings for SiC_(f) /SiC PWR accident tolerant fuel cladding

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Journal of Advanced Ceramics 2024年第1期13卷 73-85页

作者： Jinsong Yang Fang ye Laifei Cheng Kai zhao Yucong Wei Science and Technology on Thermostructural Composite Materials Laboratory Northwestern Polytechnical UniversityXi’an 710072China

To enhance the resistance of SiC_(f)/SiC to hydrothermal corrosion in the pressurized water reactor(PWR)environment,structurally tunable Ti_(3)SiC(2)-based corrosion mitigation coatings for SiC_(f)/SiC were prepared using molten salt synthesis.The influence of various process parameters,such as Si/Ti molar ratio in raw materials,annealing time,and annealing temperature,on the phase composition and the structure of the coatings was explored.Through the process control,the fabricated coatings can be either Ti_(3)SiC(2) monolithic structure or TiC/Ti_(3)SiC(2) and TiC/Ti_(3)SiC(2)/Ti_(5)Si_(3)C_(x) multilayered structures.The coatings demonstrate strong bonding to the substrate due to in-situ reaction,exhibiting tensile and shear strength of at least 26.9 and 30.8 MPa,respectively.Incorporating TiC as a transition layer further enhances the tensile and shear strength to 41.3 and 51.4 MPa,respectively.Monolithic Ti_(3)SiC(2) coatings enhance the thermal conductivity of SiC_(f)/SiC by 10%–12%.Notably,Ti_(3)SiC(2) coatings effectively protect SiC_(f)/SiC from hydrothermal corrosion,demonstrating an 83%strength retention rate compared to 71%in the control group after corrosion.However,the Ti5Si3Cx layer exhibits unsatisfactory corrosion mitigation.The Ti_(3)SiC(2) monolithic coating has higher thermal conductivity,TiC/Ti_(3)SiC(2) multi-layered coating has higher bonding strength,and both have desirable resistance to the hydrothermal corrosion.

关键词： Ti_(3)SiC(2) SiC_(f)/SiC nuclear materials hydrothermal corrosion coating