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Cooling effect of urban parks and their relationship with urban heat islands

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Atmospheric and Oceanic Science Letters 2016年第4期9卷 298-305页

作者： YANG Ping XIAO Zi-Niu ye Meng-shu China Metrological Administration Training Center BeijingChina Institute of Urban Meteorology China Meteorological AdministrationBeijingChina Institute of Atmospheric Physics Chinese Academy of SciencesBeijingChina

为了揭示城市中公园和其周边城市环境的相互关系,本文以位于北京二环以内的天坛站为例,重点分析天坛站对最邻近城市站(天安门站)的冷岛效应。研究发现,当城市公园中的周边环境热岛强度在一定的范围内变化时,城市公园站的降温作用是比较... 详细信息

为了揭示城市中公园和其周边城市环境的相互关系,本文以位于北京二环以内的天坛站为例,重点分析天坛站对最邻近城市站(天安门站)的冷岛效应。研究发现,当城市公园中的周边环境热岛强度在一定的范围内变化时,城市公园站的降温作用是比较稳定的,当城市热岛强度超过了某一临界阈值后,公园的降温作用就变得不稳定,本文将这种现象称为"冷岛增强效应"(enhanced cooling effect)。研究中选取了北京城区内六组公园-城市站,进行公园冷岛效应的进一步研究,发现水体、绿地等要素是影响冷岛作用的重要因素。

关键词：城市热岛强度冷却效果城市公园开放空间邻近地区相互作用城市环境天坛公园

T2-weighted imaging-based radiomic-clinical machine learning model for predicting the differentiation of colorectal adenocarcinoma

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 819-832页

作者： Hui-Da Zheng Qiao-Yi Huang Qi-Ming Huang Xiao-Ting Ke Kai ye shu Lin Jian-Hua Xu Department of Gastrointestinal Surgery The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Gynaecology and Obstetrics The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Computed Tomography/Magnetic Resonance Imaging The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Centre of Neurological and Metabolic Research The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Group of Neuroendocrinology Garvan Institute of Medical ResearchSydneyNSW 2010Australia

BACKGROUND The study on predicting the differentiation grade of colorectal cancer(CRC)based on magnetic resonance imaging(MRI)has not been reported *** a non-invasive model to predict the differentiation grade of CRC is of great *** To develop and validate machine learning-based models for predicting the differ-entiation grade of CRC based on T2-weighted images(T2WI).METHODS We retrospectively collected the preoperative imaging and clinical data of 315 patients with CRC who underwent surgery from March 2018 to July *** were randomly assigned to a training cohort(n=220)or a validation cohort(n=95)at a 7:3 *** were delineated layer by layer on high-resolution *** absolute shrinkage and selection operator regression was applied to screen for radiomic *** and clinical models were constructed using the multilayer perceptron(MLP)*** radiomic features and clinically relevant variables(selected based on a significance level of P<0.05 in the training set)were used to construct radiomics-clinical *** performance of the three models(clinical,radiomic,and radiomic-clinical model)were evaluated using the area under the curve(AUC),calibration curve and decision curve analysis(DCA).RESULTS After feature selection,eight radiomic features were retained from the initial 1781 features to construct the radiomic *** different classifiers,including logistic regression,support vector machine,k-nearest neighbours,random forest,extreme trees,extreme gradient boosting,light gradient boosting machine,and MLP,were used to construct the model,with MLP demonstrating the best diagnostic *** AUC of the radiomic-clinical model was 0.862(95%CI:0.796-0.927)in the training cohort and 0.761(95%CI:0.635-0.887)in the validation *** AUC for the radiomic model was 0.796(95%CI:0.723-0.869)in the training cohort and 0.735(95%CI:0.604-0.866)in the validation *** clinical model achieved an AUC of 0.7

关键词： Radiomics Colorectal cancer Differentiation grade Machine learning T2-weighted imaging

Genome-wide Expansion and Expression Divergence of the Basic Leucine Zipper Transcription Factors in Higher Plants with an Emphasis on Sorghum

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Journal of Integrative Plant Biology 2011年第3期53卷 212-231页

作者： Jizhou Wang Junxia Zhou Baolan Zhang Jeevanandam Vanitha Srinivasan Ramachandran shu-ye Jiang Institute of Botany and Temasek Life Sciences Laboratory Joint Research & Development Laboratory Institute of Botany the Chinese Academy of Sciences Beijing 100093 China Temasek Life Sciences Laboratory 1 Research Link the National University of Singapore Singapore 117604 Singapore

Plant bZIP transcription factors play crucial roles in multiple biological processes. However, little is known about the sorghum bZIP gene family although the sorghum genome has been completely sequenced. In this study, we have carried out a genome-wide identification and characterization of this gene family in sorghum. Our data show that the genome encodes at least 92 bZIP transcription factors. These bZIP genes have been expanded mainly by segmental duplication. Such an expansion mechanism has also been observed in rice, arabidopsis and many other plant organisms, suggesting a common expansion mode of this gene family in plants. Further investigation shows that most of the bZIP members have been present in the most recent common ancestor of sorghum and rice and the major expansion would occur before the sorghum-rice split era. Although these bZlP genes have been duplicated with a long history, they exhibited limited functional divergence as shown by nonsynonymous substitutions （Ka）lsynonymous substitutions （Ks） analyses. Their retention was mainly due to the high percentages of expression divergence. Our data also showed that this gene family might play a role in multiple developmental stages and tissues and might be regarded as important regulators of various abiotic stresses and sugar signaling.

关键词： Transcription factors Transcription Plants Planting Families Genes Sorghum Genomes Stress Data

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温润如玉:中国美学原点与“润”的观念起源

南京大学学报:哲学.人文科学.社会科学 2023年第4期60卷 58-65,159,160页

作者：叶舒宪上海交通大学中国语言文学系上海市200240

对于上下五千年的中国文明而言,玉文化研究相较其他物质文化方面,具有无可比拟的优势,这也是当下新文科拓展知识创新点之所在。中国美学学术重建应回归本土视角和本土话语,根据考古新资料重建万年中国观的深度历史大视野和知识更新格局... 详细信息

对于上下五千年的中国文明而言,玉文化研究相较其他物质文化方面,具有无可比拟的优势,这也是当下新文科拓展知识创新点之所在。中国美学学术重建应回归本土视角和本土话语,根据考古新资料重建万年中国观的深度历史大视野和知识更新格局,锁定华夏文明核心价值观的原型物质——美玉,通过上五千年的鉴玉经验积淀过程分析,诠释下五千年“君子温润如玉”人格理想及其审美实践底蕴。万年玉文化传承在审美聚焦方面的两个本土核心问题是:温润如玉的价值判断究竟从何而来?为什么后代儒家的人格理想表达,要借助于玉的温润之美作为元隐喻?前一问的答案,将是解说后一问的认识前提。这样的连锁解答思路需要诉诸上五千年的先民审美感知世界。通过聚焦古人鉴玉的核心审美标准——华夏独有的美学关键词“润”的观念起源问题,可以发现,“温润”是古人通过佩玉和盘玉的把玩实践检验后提炼出来的美学理想和人格理想。

关键词：格物致知中国美学感觉学润泽玉德

Analysis of Serum Metabolic Profile by Ultra-performance Liquid Chromatography-mass Spectrometry for Biomarkers Discovery： Application in a Pilot Study to Discriminate Patients with Tuberculosis

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Chinese Medical Journal 2015年第2期128卷 159-168页

作者： shuang Feng Yan-Qing Du Li Zhang LeiZhang Ran-Ran Feng shu-ye Liu Department of Clinical Laboratory Haihe Hospital Respiratory Disease Research Institute Tianjin 300350 China Department of Clinical Laboratory Institute for Hepatology of the Third Center Hospital Tianjin 300350 China

Background：Tuberculosis （TB） is a chronic wasting inflammatory disease characterized by multisystem involvement,which can cause metabolic derangements in afflicted *** signatures have been exploited in the study of several ***,the serum that is successfully used in TB diagnosis on the basis of metabolic profiling is not by ***：Orthogonal partial least-squares discriminant analysis was capable of distinguishing TB patients from both healthy subjects and patients with conditions other than ***,TB-specific metabolic profiling was *** of potential biomarkers for differentiating TB active from non-TB diseases were identified using Mann-Whitney *** logistic regression analysis of metabolites was calculated to determine the suitable biomarker group that allows the efficient differentiation of patients with TB active from the control ***：From among 271 participants,12 metabolites were found to contribute to the distinction between the TB active group and the control *** metabolites were mainly involved in the metabolic pathways of the following three biomolecules：Fatty acids,amino acids,and *** receiver operating characteristic curves of3D,7D,and 11D-phytanic acid,behenic acid,and threoninyl-γ-glutamate exhibited excellent efficiency with area under the curve （AUC） values of 0.904 （95% confidence interval [CI]：0.863-0.944）,0.93 （95% CI：0.893-0.966）,and 0.964 （95% CI：0.941-0.988）,*** largest and smallest resulting AUCs were 0.964 and 0.720,indicating that these biomarkers may be involved in the disease *** combination of lysophosphatidylcholine （18∶0）,behenic acid,threoninyl-γ-glutamate,and presqualene diphosphate was used to represent the most suitable biomarker group for the differentiation of patients with TB active from the control subjects,with an AUC value of ***：The metabolic analysis results identified new serum biomarkers that

关键词： Metabolites Orthogonal Partial Least-squares Discriminant Analysis Serum Tuberculosis Ultra-performance LiquidChromatography-mass Spectrometry

四重证据·N级编码·“玉教”理论——叶舒宪先生访谈兼答李永平教授

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陕西师范大学学报（哲学社会科学版） 2016年第5期45卷 5-10页

作者：叶舒宪栾为上海交通大学人文学院上海200240

自1996年中国文学人类学研究会成立至今,文学人类学在近20年的时间里发展迅速,不断提出新的学术探索命题并逐渐积累成一种理论体系的创新。"四重证据"是该学科标志性的理论工具,是人类学"田野"与文学"场域"对接的跨学科研究成果。其在... 详细信息

自1996年中国文学人类学研究会成立至今,文学人类学在近20年的时间里发展迅速,不断提出新的学术探索命题并逐渐积累成一种理论体系的创新。"四重证据"是该学科标志性的理论工具,是人类学"田野"与文学"场域"对接的跨学科研究成果。其在神话学领域的应用,产生出文化符号的"N级编码"理论,将西方"神话—原型"批评的应用范围向前大大推进了一步。在对中国文学和文化"大传统"探寻过程中,文学人类学提出了华夏"玉教"理论。从"四重证据"到"N级编码"再到"玉教"理论,中国文学人类学一直努力通过本土神话的溯源研究为中国文化找回失落已久的信仰之根。

关键词：四重证据 N级编码 “玉教” 文学人类学

Synergistic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and N-nitrosodiethylamine on Cell Malignant Transformation

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Biomedical and Environmental Sciences 2013年第5期26卷 323-330页

作者： ZHANG Lei ZHAO Rui ye shu Qing ZHOU Ling WU Yong Ning ZENG Yi Key Laboratory of Food Safety Risk Assessment Ministry of HealthChina National Center for Food Safety Risk Assessment College of Life Science and Bio-engineering Beijing University of Technology National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention

Objective The present paper aims to investigate the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin （TCDD） and N-nitrosodiethylamine （DEN） on tumorigenesis and its potential mechanism. Methods The potentials of TCDD and DEN in separation or in combination to induce malignant transformation were tested in Balb/c 3T3 cells by using a cell transformation assay method. The possible mechanism of observed effects was studied further by adding α-naphthoflavone （α-NF）, a competitive binding agent of TCDD, to the Aryl hydrocarbon receptor （AhR） pathway. The mRNA expressions of Cyp1a1 and Cyp2a5 gene in Balb/c 3T3 cells treated by DEN and TCDD in separation or in combination with or without presence of α-NF were measured with fluorescence quantification RT-PCR technique. Results The cell transformation frequency （TF） was significantly higher in case of induction with TCDD in combination with DEN, as compared to that with either TCDD or DEN alone. These effects were not inhibited via α-NF. The mRNA expression levels of both Cyp1a1 and Cyp2a5 were enhanced by TCDD treatment alone, but this inducible effect was blocked in cells treated by TCDD and DEN in combination. Conclusion TCDD and DEN had a significant synergistic effect on tumorigenesis when they were used in combination. AhR pathway may not be the key mechanism of this synergistic effect. Thus, it is necessary to further test the potential mechanism involved in cancer development.

关键词： Dioxin Nitrosodiethylamine Cell transformation Tumorigenesis

执天之“机”——《阴符经》天人关系中“机”的思想研究

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世界宗教文化 2023年第4期 107-113页

作者：郭文娅舒也南京大学哲学系雅典大学哲学系

《阴符经》以“贼”“盗”为特色的天人关系是道教天人关系认识上的飞跃,天人之间并非相生相养,而是相互窃取,这实际上是基于天人不一的信念。把握“贼”“盗”到来之“机”是天人沟通的关键。“机”中蕴含着天的维度和人的维度,人通过... 详细信息

《阴符经》以“贼”“盗”为特色的天人关系是道教天人关系认识上的飞跃,天人之间并非相生相养,而是相互窃取,这实际上是基于天人不一的信念。把握“贼”“盗”到来之“机”是天人沟通的关键。“机”中蕴含着天的维度和人的维度,人通过执天之“机”实现天人合一。“天”不再具有神圣性,“人”也不再被动“无为”。《阴符经》提供了一种天人关系的新型典范,这种新型的天人关系既没有削减天的不测性,也没有夸大人的能力。

关键词：《阴符经》天人关系 “机”

Unilateral spatial neglect,global processing deficit and prosopagnosia following right hemisphere stroke:a case report

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Chinese Medical Journal 2005年第21期118卷 1846-1848页

作者： LU Xue-song ye Jing ZHOU shu LU Bing-xun CHEN Xian-hong Department of Neurology Nanfang Hospital Southern Medical University Guangzhou 510515 China

Although unilateral spatial neglect, global processing deficit, or prosopagnosia followingbrain damage has been usually reported separately, to our knowledge, a report on a patient with the three mentioned syndromes has not been reported. We now present a case that developed unilateral spatial neglect, global processing deficit and prosopagnosia after right hemisphere stroke in September 2004.

关键词： attention prosopagnosia right hemisphere