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长江口一次持续性强浓雾过程特征和成因分析

海洋预报 2024年第1期41卷 74-82页

作者：韩苗苗高雅文钟剑杜树浩周彤中国卫星海上测控部江苏江阴214431

使用船载观测资料、FNL再分析资料和葵花八号云图资料,对2022年3月11—14日发生于长江口的持续性浓雾过程进行研究分析,并归纳总结了预报的实用性方法。结果表明:本次浓雾过程包含辐射雾和锋面平流雾,持续时间长,影响范围广,雾区在锋面... 详细信息

使用船载观测资料、FNL再分析资料和葵花八号云图资料,对2022年3月11—14日发生于长江口的持续性浓雾过程进行研究分析,并归纳总结了预报的实用性方法。结果表明:本次浓雾过程包含辐射雾和锋面平流雾,持续时间长,影响范围广,雾区在锋面的前后部都相继出现,且锋面移动往往影响着雾的移动。在雾的生消和维持过程中,气温和相对湿度通常呈负相关,温度露点差和能见度呈正相关,当温度露点差大于3℃时,长江口也会有雾生成,但能见度不低于3 km。雾生时段通常盛行偏南风和偏北风,偏西风和西北风则会导致相对湿度迅速下降,不利于雾的形成和维持。可见光云图上雾的特征明显,颜色纹理均匀,边界清晰整齐,外围无丝状或纤维状云系扩散,而红外云图上对应处是一片灰暗区,只有边界隐约可见。

关键词：浓雾长江口雾生消过程水汽输送预报

Cotton flooding and drought analysis regarding growth stages in Hubei,China,using a daily agrometeorological index

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International Journal of Agricultural and Biological Engineering 2023年第4期16卷 173-183页

作者： Long Qian Cheng Chen Xiaohong Chen Wenzhi Zeng yawen gao Kenan Deng School of Civil Engineering Sun Yat-sen UniversityGuangzhou 510275China State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminatsy Shanghai 200233China State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan 430072China

Cotton yield is restricted worldwide by flooding and drought that occur across various growth *** this study,cotton flooding and drought in Hubei(a major cotton-production province in China)from 1961 to 2019 were analyzed regarding growth stages through a daily index named the standardized antecedent precipitation evapotranspiration index(SAPEI).In addition,the impacts of flooding and drought on cotton climatic yield were quantified using multiple regression *** results showed that the temporal trends of cotton flooding and drought intensities were generally smooth,except for an obvious downward trend for cotton drought intensity at the flowering and boll-forming ***,cotton drought intensity varied more drastically than that of flooding over the ***-flooding proneness was much greater than cotton-drought proneness at all growth stages,and the most flooding-prone and drought-prone periods were identified as the flowering and boll-forming stage and the budding stage,*** terms of spatial distribution,northeastern Hubei and southwestern Hubei were most prone to flooding and drought,*** SAPEI-based regression model(R2=0.490,p<0.001),obviously outperforming the SPEI-based model(R2=0.278,p<0.05),revealed that both cotton flooding and drought exhibited negatively significant effects on cotton climatic yield and that the yield-reducing effect of cotton flooding was much greater than that of ***,when growth stages were further considered using regression analysis,only the flowering and boll-forming stage was detected with a significant yield-reducing effect of cotton *** conclusion,the SAPEI can effectively assist in monitoring cotton flooding and drought;cotton flooding,especially during the flowering and boll-forming stage and that occurring in northeastern Hubei,is the key issue for cotton field water management in Hubei.

关键词： irrigation drainage climatic yield waterlogging

单细胞转录组测序联合孟德尔随机化分析揭示慢性鼻窦炎中CTSC的关键作用

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中华耳鼻咽喉头颈外科杂志 2024年第6期59卷 551-559页

作者：周世灿赖菊范锴李敬文徐夏月姚春艳龙波锦赵传亮车娜高雅玟余少卿同济大学同济医院耳鼻咽喉头颈外科变态反应科上海200065

目的:旨在深入探索慢性鼻窦炎(CRS)的分子机制,识别关键细胞亚群和基因,构建有效的诊断模型,并筛选潜在的治疗药物。方法:通过单细胞转录组测序数据鉴定CRS中的关键细胞亚群。通过高维加权基因共表达网络分析(high dimensional weighted... 详细信息

目的:旨在深入探索慢性鼻窦炎(CRS)的分子机制,识别关键细胞亚群和基因,构建有效的诊断模型,并筛选潜在的治疗药物。方法:通过单细胞转录组测序数据鉴定CRS中的关键细胞亚群。通过高维加权基因共表达网络分析(high dimensional weighted gene co-expression network analysis,hdWGCNA)和多种机器学习算法的联合应用,筛选CRS的关键基因并构建CRS的诊断模型。通过孟德尔随机化和共定位分析进行因果推断分析。使用分子对接技术进行靶点药物的鉴定,并通过免疫荧光染色对生信分析的结果进行验证。采用Graphpad Prism、R、python和Adobe Illustrator软件进行数据及图像处理。结果:CRS尤其是嗜酸性慢性鼻窦炎伴鼻息肉(ECRSwNP)中基底细胞和基上皮细胞占比增加(P=0.001)。hdWGCNA显示“黄色模块”与CRS中基底细胞和基上皮细胞密切相关。采用单因素逻辑回归和最小绝对值收敛和选择算法(least absolute shrinkage and selection operator,LASSO)筛选出13个关键基因(CTSC、LAMB3、CYP2S1、TRPV4、ARHGAP21、PTHLH、CDH26、MRPS6、TENM4、FAM110C、NCKAP5、SAMD3和PTCHD4)。基于这13个基因,使用多种机器学习算法构建出有效的CRS诊断模型(AUC=0.958)。孟德尔随机化分析显示组织蛋白酶C(cathepsin C,CTSC)与CRS具有因果关系(逆方差加权:OR=1.06,P=0.006),共定位分析证实CTSC与CRS具有共享的遗传变异(PPH4/PPH3>2)。分子对接结果显示,对乙酰氨基酚与CTSC具有较好的结合能力(结合能:-5.638 kcal/mol)。免疫荧光染色实验表明CRS中CTSC^(+)细胞增多。结论:本研究综合运用多种生物信息学方法,识别了CRS中的关键细胞类型和基因,构建了有效的诊断模型,强调了CTSC在CRS中的关键作用,为CRS的治疗提供了新的靶点。

关键词：鼻窦炎单细胞转录组测序孟德尔随机化组织蛋白酶C

Removal of kathon by UV-C activated hydrogen peroxide:Kinetics,mechanisms,and enhanced biodegradability assessment

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Chinese Journal of Chemical Engineering 2024年第1期65卷 178-187页

作者： Jinzhi Cui Guiqiao Wang Xing Rong Wensu gao Yaxin Lu yawen Luo Lichao Zhang Zhongfa Cheng Canzhu gao School of Environmental Science and Engineering Shandong UniversityQingdao 266237China Shandong Taihe Technologies Co. Ltd.Zaozhuang 250031China

Kathon(CMI-MI),a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one(CMI)and 2-methyl-4-isothiazolin-3-one(MI),was extensively used in industry as a nonoxidizing biocide or ***,it would show adverse effects on aquatic life when it is discharged into surface *** this study,the removal performance,parameter influence,degradation products and enhancement of subsequent biodegradation of CMI-MI in UV/H_(2)O_(2)system were systematically *** degradation rate of CMI-MI could reach 90%under UV irradiation for 20 min when the dosage of H_(2)O_(2)was 0.3 mmol·L^(–1).The DOC(dissolved organic carbon)mineralization rate of CMI-MI could reach 35%under certain conditions([H_(2)O_(2)]=0.3 mmol·L^(–1),UV irradiation for 40 min).kobs was inversely proportional to the concentration of CMI-MI and proportional to the concentration of H_(2)O_(2).The degradation rate of CMIMI was almost unchanged in the pH range from 4 to *** the presence of CO_(3)^(2-)inhibited the removal rate of CMI-MI,SO_(4)^(2-),Cl^(-),NO_(3)^(-),and NH_(4)^(+) did not interfere with the degradation of CMI-MI in the *** was found that UV/H_(2)O_(2)system had lower energy consumption and more economic advantage compared with UV/PS system by comparing the EEO(electric energy per order)values under the same *** main organic products were identified,namely HCOOH and CH_(3)NH_(2).There’s also the formation of Cl^(-)and SO_(4)^(2-).After UV and UV/H_(2)O_(2)photolysis,the biochemical properties of CMI-MI solution were obviously improved,especially the UV/H_(2)O_(2)treatment effect was better,indicating that UV/H_(2)O_(2)technology is expected to combine with biotechnology to remove CMI-MI effectively and environmentally friendly from wastewater.

关键词： Kathon UV/H_(2)O_(2) Biological degradation Circulating cooling water

Role of the portal system in liver regeneration:From molecular mechanisms to clinical management

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Liver Research 2024年第1期8卷 1-10页

作者： Hanzhi Xu Xun Qiu Zhoucheng Wang Kai Wang yawen Tan Fengqiang gao Marcos Vinicius Perini Xiao Xu Zhejiang University School of Medicine HangzhouZhejiangChina Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province HangzhouZhejiangChina Department of Surgery University of MelbourneAustin HealthHeidelbergVictoriaAustralia

The liver has a strong regenerative capacity that ensures patient recovery after hepatectomy and liver *** portal system plays a crucial role in the dual blood supply to the liver,making it a significant factor in hepatic *** surgical strategies,such as portal vein ligation,associating liver partition and portal vein ligation for staged hepatectomy,and dual vein embolization,have high-lighted the portal system's importance in liver *** hepatectomy or liver trans-plantation,the hemodynamic properties of the portal system change dramatically,triggering regeneration via shear stress and the induction of ***,excessive portal hyperperfusion can harm the liver and negatively affect patient ***,as the importance of the gut-liver axis has gradually been revealed,the effect of metabolites and cytokines from gut microbes carried by portal blood on liver regeneration has been *** these perspectives,this review outlines the molecular mechanisms of the portal system's role in liver regeneration and summarizes therapeutic strategies based on the portal system intervention to promote liver regeneration.

关键词： Portal system Liver regeneration Hemodynamic properties Gut microbiota Therapeutic strategies

Industry-Oriented Detection Method of PCBA Defects Using Semantic Segmentation Models

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1438-1446页

作者： Yang Li Xiao Wang Zhifan He Ze Wang Ke Cheng Sanchuan Ding Yijing Fan Xiaotao Li yawen Niu Shanpeng Xiao Zhenqi Hao Bin gao Huaqiang Wu Department of Internet of Things Technology and Application China Mobile Research InstituteBeijing 100053China Beijing Advanced Innovation Center for Integrated Circuits the School of Integrated CircuitTsinghua UniversityBeijing 100084China SigmaStar Technology Limited Xiamen 361199China IEEE

Automated optical inspection(AOI)is a significant process in printed circuit board assembly(PCBA)production lines which aims to detect tiny defects in *** AOI equipment has several deficiencies including low throughput,large computation cost,high latency,and poor flexibility,which limits the efficiency of online PCBA *** this paper,a novel PCBA defect detection method based on a lightweight deep convolution neural network is *** this method,the semantic segmentation model is combined with a rule-based defect recognition algorithm to build up a defect detection *** improve the performance of the model,extensive real PCBA images are collected from production lines as *** optimization methods have been applied in the model according to production demand and enable integration in lightweight computing *** results show that the production line using our method realizes a throughput more than three times higher than traditional *** method can be integrated into a lightweight inference system and pro-mote the flexibility of *** proposed method builds up a general paradigm and excellent example for model design and optimization oriented towards industrial requirements.

关键词： Automated optical inspection(AOI) deep learning defect detection printed circuit board assembly(PCBA) semantic segmentation.

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中国地方企业主义:多重身份与实践策略

热带地理 2024年第4期44卷 608-620页

作者：杨雅雯高金龙中国科学院流域地理学重点实验室中国科学院南京地理与湖泊研究所南京210008 中国科学院大学北京100049

改革开放以来,中国社会经历了市场化、分权化和全球化的剧烈变迁,地方政府的行为逻辑也随之发生深刻变化。在转型中,地方政府越来越明显地表现出原本属于企业的行为特征,并创造了“中国模式”的经济奇迹和独特空间现象,被广泛称为“地... 详细信息

改革开放以来,中国社会经历了市场化、分权化和全球化的剧烈变迁,地方政府的行为逻辑也随之发生深刻变化。在转型中,地方政府越来越明显地表现出原本属于企业的行为特征,并创造了“中国模式”的经济奇迹和独特空间现象,被广泛称为“地方企业主义”。随着城镇化和经济社会发展进入攻坚期,探索地方治理能力提升和地方发展模式转型的有效路径,成为社会各界共同关注的重要话题。文章从人文经济地理学研究视角切入,系统梳理地方企业主义理论的兴起与发展历程,从战略、话语和方式等3方面构建中国地方企业主义的分析框架。在此基础上,从地方政府的差异化“身份”视角入手,梳理中国地方政府为实现企业主义治理而采取的实践策略,总结了中国地方企业主义不同于西方的“中国特性”。研究认为:1)相较广泛参与的西方民主制度,中国的地方企业主义更具行政干预的色彩,各地政府凭借其在行政、公共资源等方面的垄断性权利在地方的企业化实践中发挥着主导作用;2)分权化改革虽然赋予了地方政府一定的经济发展的权责,但国家的干预仍无处不在,地方企业主义战略的最终目的是维护国家权力;3)进入高质量发展的新阶段,地方企业主义的内涵和外在形式不断扩展,经济增长不再是地方发展的主旋律,如何在发展中兼顾效率和公平的问题成为现阶段政府的重要议题。最后,对企业化治理的可持续性进行讨论,并提出地方企业主义在乡村治理研究中的拓展方向。

关键词：地方企业主义政府角色新自由主义全球城市化治理中国

Soft,body conformable electronics for thermoregulation enabled by kirigami

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Bio-Design and Manufacturing 2024年第4期7卷 453-462页

作者： Lung Chow Guangyao Zhao Pengcheng Wu Xingcan Huang Jiyu Li Jian Li Wanying Wang Guihuan Guo Zhiyuan Li Jiachen Wang Jingkun Zhou yawen Yang Yuyu gao Binbin Zhang Qiang Zhang Dengfeng Li Ya Huang Kuanming Yao Jian Lu Xinge Yu Department of Biomedical Engineering City University of Hong KongHong Kong 999077China Hong Kong Centre for Cerebro-Cardiovascular Health Engineering Hong Kong 999077China Department of Biomedical Sciences City University of Hong KongHong Kong 999077China Department of Mechanical Engineering City University of Hong KongHong Kong 999077China

The application of thermoelectric devices(TEDs)for personalized thermoregulation is attractive for saving energy while balancing the quality of *** that directly attach to human skin remarkably minimized the energy wasted for cooling the entire ***,facing the extreme dynamic geometry change and strain of human skin,conventional TEDs cannot align with the contour of our bodies for the best thermoregulation ***,we designed a kirigami-based wearable TED with excellent water vapor permeability,flexibility,and *** analysis and experimental results reveal that our product can withstand various types of large mechanical deformation without circuit *** stated outcome and proposed facile approach not only reinforce the development of wearable TEDs but also offer an innovative opportunity for different electronics that require high conformability.

关键词： Thermoregulation Thermoelectric Kirigami Body conformable Wearable

新冠肺炎疫情背景下云南禁毒工作堵源截流的思考

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云南警官学院学报 2022年第3期 20-24页

作者：高雅文云南警官学院(党委)办公室云南昆明650223

云南在全球蔓延的新冠肺炎疫情防控中,坚持“外防输入、内防反弹”总策略和“动态清零”总方针,肩负为国守边的重大责任。云南省实施强边固防等一系列强有力的措施,同时严厉打击偷越国边境等违法犯罪行为,治理“三非”外国人问题,严格... 详细信息

云南在全球蔓延的新冠肺炎疫情防控中,坚持“外防输入、内防反弹”总策略和“动态清零”总方针,肩负为国守边的重大责任。云南省实施强边固防等一系列强有力的措施,同时严厉打击偷越国边境等违法犯罪行为,治理“三非”外国人问题,严格管理入境人员,将疫情挡在了国门之外,也使“金三角”地区毒品向云南境内渗透趋势发生了新的变化。面对云南边境管控的铜墙铁壁,“金三角”地区毒品被迫改变分销路线,或是采用物流寄递等更加隐蔽的方式向云南境内渗透。毒品过境通道被阻,使得境内毒品紧缺价格数倍增长,但全省毒品滥用形势向好。毒品犯罪形势存在因疫情缓解而反弹的风险,仍需保持高压态势,常态开展边境巡防,织密查缉网络,增强大数据运用能力,全力整治物流寄递贩毒,巩固堵源截流成果。

关键词：新冠肺炎疫情毒品犯罪堵源截流