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Identifying key traits in high-yielding rice cultivars for adaptability to both temperate and tropical environments

The Crop Journal 2019年第5期7卷 685-693页

作者： Toshiyuki Takai Patrick Lumanglas Eliza Vie Simon Yumiko arai-Sanoh Hidetoshi Asai Nobuya Kobayashi Japan International Research Center for Agricultural Sciences TsukubaIbaraki 305-8686Japan International Rice Research Institute DAPO Box 7777Metro ManilaPhilippines Institute of Crop Science National Agriculture and Food Research Organization(NARO)TsukubaIbaraki 305-8518Japan

Increasing rice yield potential is a continuous challenge posed by world population *** increase yield potential,favorable alleles of valuable genes need to be accumulated in promising *** conducted comparative yield trials for two years in Tsukuba,Japan,in a temperate region and at the International Rice Research Institute(IRRI),Philippines,in a tropical region using five high-yielding rice cultivars:Takanari and Hokuriku193,developed in Japan,and IR64,NSIC Rc158,and YTH183,developed in the *** plus genotype×environment interaction(GGE)biplot analysis across four environments(two regions×two seasons)classified the five cultivars into four categories:Takanari and YTH183 showed high adaptability to both tropical and temperate regions,Hokuriku193 was suitable for temperate regions,NSIC Rc158 was suitable for the tropics,and IR64 was inferior to the other cultivars in both *** high yield and adaptability in Takanari and YTH183 were attributed to their large sink capacity with good grain *** plant type for high yield was different,however,between the two cultivars;Takanari was a panicle-weight type,whereas YTH183 was a panicle-number *** of F2 progeny of a cross between Takanari and YTH183 showed transgressive segregation for number of panicles per plant as well as number of spikelets per panicle,leading some F2 plants to produce more spikelets per plant(corresponding to larger sink size)than the parental cultivars in both *** results suggest the possibility of developing rice cultivars with high yield potential in both temperate and tropical regions by crossing temperate with tropical high-yielding cultivars.

关键词： Adaptability Genotype×environment interaction Rice Sink capacity Yield potential

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Can endoscopic submucosal dissection be safely performed in a smaller specialized clinic?

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World Journal of Gastroenterology 2013年第4期19卷 528-535页

作者： Naondo Sohara Satoshi Hagiwara Riki arai Haruhisa Iizuka Yasuhiro Onozato Satoru Kakizaki Department of Endoscopy and Endoscopic Surgery Shirakawa ClinicMaebashiGunma 371-0051Japan Department of Medicine and Molecular Science Gunma University Graduate School of MedicineMaebashiGunma 371-8511Japan

AIM:To investigate whether endoscopic submucosal dissection(ESD) can be safely performed at small clinics,such as the Shirakawa ***:One thousand forty-seven ESDs to treat gastrointestinal tumors were performed at the Shirakawa Clinic from April 2006 to March *** efficacy,technical feasibility and associated complications of the procedures were *** ESD procedures were performed by five *** was induced with propofol for esophagogastorduodenal ***:One thousand forty-seven ESDs were performed to treat 64 patients with esophageal cancer(E),850 patients with gastric tumors(G:764 patients with cancer,82 patients with adenomas and four others),four patients with duodenal cancer(D) and 129 patients with colorectal tumors(C:94 patients with cancer,21 patients with adenomas and 14 others).The en bloc resection rate was 94.3%(E:96.9%,G:95.8%,D:100%,C:79.8%).The median operation time was 46 min(range:4-360 min) and the mean size of the resected specimens was 18 mm(range:2-150 mm).No mortal complications were observed in association with the ESD *** occurred in 12 cases(1.1%,E:1 case,G:9 cases,D:1 case,C:1 case) and postoperative bleeding occurred in 53 cases(5.1%,G:51 cases,D:1 case,C:1 case);however,no case required either emergency surgery or blood *** of the perforations and postperative bleedings were resolved by endoscopic clipping or *** other problematic complication observed was pneumonia,which was treated with conservative ***:ESD can be safely performed in a clinic with established therapeutic methods and medical services to address potential complications.

关键词： Endoscopic submucosal dissection Complication Perforation Clinic

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Non-ossifying fibromas: Case series, including in uncommon upper extremity sites

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World Journal of Orthopedics 2017年第7期8卷 561-566页

作者： Akio Sakamoto Ryuzo arai Takeshi Okamoto Shuichi Matsuda Department of Orthopaedic Surgery Graduate School of Medicine Kyoto University

AIM To investigate non-ossifying fibromas(NOFs) common fibrous bone lesions in children that occur in bones of the lower *** We analyzed 44 cases of NOF including 47 lesions, which were referred with a working diagnosis of neoplastic lesions. Lesions were located in the upper extremities(1 proximal humerus, 1 distal radius) and the lower extremities(25 distal femurs, 12 proximal and 4 distal tibias, and 4 proximal fibulas).RESULTS Three cases had NOFs in multiple anatomical locations(femur and fibula in 1 case, femur and tibia in 2 cases). Overall, larger lesions > 4 cm and lesion expansion at the cortex were seen in 21% and 32% of cases, respectively. Multiple lesions with bilateral symmetry in the lower extremities suggest that these NOFs were developmental bone defects. Two patients suffered from fracture and were treated without surgery, one in the radius and one in the femur. Lesions in the upper extremities(i.e., humerus of a 4-year-old female and radius of a 9-year-old male) expanded at the cortex and lesion size increased with slow *** NOFs in the lower extremity had fewer clinical problems, regardless of their size and expansiveness. In these two upper extremity cases, the NOFs had aggressive biological features. It seems that there is a site specific difference, especially between the upper extremity and the lower extremity. Furthermore, NOFs in the radius are predisposed to fracture because of the slender structure of the radius and the susceptibility to stress.

关键词： Non-ossifying fibroma Humerus Radius Fibula Upper extremity

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Ultrasound-triggered three dimensional hyaluronic acid hydrogel promotes in vitro and in vivo reprogramming into induced pluripotent stem cells

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Bioactive Materials 2024年第8期38卷 331-345页

作者： Deogil Kim Min-Ju Lee Yoshie arai Jinsung Ahn Gun Woo Lee Soo-Hong Lee Department of Biomedical Engineering Dongguk University-Seoul04620SeoulSouth Korea

Cellular reprogramming technologies have been developed with different physicochemical factors to improve the reprogramming efficiencies of induced pluripotent stem cells(iPSCs).Ultrasound is a clinically applied noncontact biophysical factor known for regulating various cellular behaviors but remains uninvestigated for cellular ***,we present a new reprogramming strategy using low-intensity ultrasound(LIUS)to improve cellular reprogramming of iPSCs in vitro and in *** 3D microenvironment conditions,increased LIUS stimulation shows enhanced cellular reprogramming of the *** cellular reprogramming process facilitated by LIUS is accompanied by increased mesenchymal to epithelial transition and histone *** stimulation transiently modulates the cytoskeletal rearrangement,along with increased membrane fluidity and mobility to increase HA/CD44 ***,LIUS stimulation with HA hydrogel can be utilized in application of both human cells and in vivo environment,for enhanced reprogrammed cells into ***,LIUS stimulation with a combinatorial 3D microenvironment system can improve cellular reprogramming in vitro and in vivo environments,which can be applied in various biomedical fields.

关键词： Induced pluripotent stem cell Cellular reprogramming Low-intensity ultrasound Biophysical stimulation Cytoskeletal rearrangement

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Isolation of the Left Subclavian Artery in D-Transposition of the Great Arteries with Right Aortic Arch

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Congenital Heart Disease 2021年第4期16卷 369-371页

作者： Kotaro Hine Kohei Ogata Keiko Saitou Norio Mizukaki Hiroko arai Hitoshi Yoda Department of Neonatology Toho University Omori Medical CenterTokyo143-8541Japan

Abnormal branching of the aorta associated with the right aortic arch(RAA)has been reported as isolation of left subclavian artery(ILSA),isolation of left common carotid artery,isolation of brachiocephalic *** is a rare aortic branch anomaly that originates in the left subclavian artery from the pulmonary artery via ductus *** reports have described ILSA associated with 22q11.2 deletion syndrome and tetralogy of ***,we present a very unusual case of RAA with ILSA associated with D-transposition of the great arteries and inferior vena cava interrupted with azygos continuation.

关键词： Isolated left subclavian artery transposition of the great arteries RAA ILSA

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Magnetically Driven Soft Continuum Microrobot for Intravascular Operations in Microscale

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Cyborg and Bionic Systems 2022年第1期2022卷 265-272页

作者： Dan Liu Xiaoming Liu Zhuo Chen Zhaofeng Zuo Xiaoqing Tang Qiang Huang Tatsuo arai Key Laboratory of Biomimetic Robots and Sytems Ministry of EducationState Key Laboratory of Ielligent Control and Decision.of Complex SystemBeijing Advanced Innovation Center for Itelligent Robots and Systemsand School of Mechatronical EngineeringBeijing Institute of TechnologyBejing 100081China Center for Neuroscience and Biomedical Engineering The University of Electro-CommunicationsTokyo 1828585Japan

Remotely controlled soft continuum robots with active steering capability have broad prospects in medical ***,conventional continuum robots have the miniaturization *** paper presents a microscale soft continuum microrobot with steering and locomotion capabilties based on magnetic field *** magnetically driven soft continuum microrobot is made of NdFeB particles and polyd imethylsiloxane(PDMS),and it can be as small as 200 pum in ***,a hydrogel layer is covered on the surface of the microrobot,which not only overcomes the adhesion force between the microobjects and the soft tip but also reduces the friction between the microrobot and *** performance test indicates the soft continuum microrobot featured excellent control and steering *** experimental results demonstrate that the soft continuum microrobot can travel through the microfluidic channel by its own vibration and flexibly steer in a bifurcation ***,the micromanipulation of microbeads in the microfluidic channels proves that the proposed microscale soft continuum microrobot has a great potential for intravascu lar manipu lation.

关键词： friction robot overcome

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Circulating tumor cells and cell-free tumor DNA analyses in urothelial cancer using the LiquidBiopsy platform

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Current Urology 2022年第2期16卷 99-106页

作者： Minoru Kobayashi Hideyuki Abe Kyoko arai Satoshi Murakami Takao Kamai Department of Urology Utsunomiya Memorial HospitalTochigi320-0811Japan Department of Urology Yuai Memorila HospitalIbarakiJapan Department of Urology Dokkyo Medical UniversityTochigiJapan Diagnostic Division Abbott Japan LLCTokyoJapan

Background:Emerging data suggested that liquid biopsy such as detection of circulating tumor cells(CTCs)and cell-free tumor DNA analysis augments the management of patients with urothelial cancer(UC).We presented our pilot experience of liquid biopsy using the Ion Torrent platform to detect CTCs and genomic alterations in *** and methods:Blood or urine samples from 16 patients were subjected to CTC and plasma/urine cell-free tumor DNA isolation for next generation sequencing(NGS)using the Ion S5 system to detect mutations among 50 oncogenes on the Ion AmpliSeq Cancer Hotspot ***:The Ion Torrent platform detected a higher number of CTCs than those in previous studies using the CellSearch^(TM)***,mutations were detected in 13/16(81.3%)patients with a median number of 18(range 12-25).NGS isolated 17 hotspot mutations from 11 genes and 41 novel genomic alterations from 24 genes,some of which are supposed to be clinically ***:The Ion Torrent platform efficiently detected CTCs compared with previous *** with the present system also allowed for detection of gene alterations which are likely to be therapeutic targets and provided an attractive tool to guide personalized therapy for patients with advanced UC.

关键词： Cell-free DNA Cell-free tumor DNA Circulating tumor cell Next generation sequencing Urothelial cancer

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Electrochemical behavior of the V（ Ⅳ ）／V（ Ⅴ ）couple in sulfuric acid medium

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电池 2003年第6期33卷 339-341页

作者： S.Iwasa Y.Wei B.Fang T.arai M.Kumagai InstituteofResearch＆Innovation 1201TakadaKashiwaChiba277-0861Japan

The electrochemical behavior of the V( Ⅳ )/V( Ⅴ ) redox couple at a glassy carbon electrode was investigated. Cyclic voltammetry(CV) results indicated that electrode process of the V( Ⅳ )/V( Ⅴ ) couple was electrochemically quasi-reversible with a rate constant of 8 × 10^-4 cm/S . Increasing concentration of sulfuric acid was electrochemically favourable for the V( Ⅳ )/V( Ⅴ )couple while elevated temperature was unfavourable for this system. Constant-current electrolysis results showed that current efficiency of more than 95 % could be achieved, which indicated that the V( Ⅳ )/V( Ⅴ ) couple had excellent electrolytic performance and was suitable for the application as the anolyte of redox flow batteries.

关键词：全钒氧化还原电池 RFB 可充电电池循环伏安法电解液阳极

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Micro-Fabrication on Surface of Transparent Solid Materials by Nanosecond Laser

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材料科学与工程（中英文B版） 2012年第8期2卷 471-481页

作者： Takeji arai Research and Development Initiative Chuo University 1-13-27 Kasuga Bunlryou-ku Tokyo12-8 5 51 Japan

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Magnetic Microrobots Fabricated by Photopolymerization and Assembly

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Cyborg and Bionic Systems 2023年第1期4卷 41-46页

作者： Xiyue Liang Yue Zhao Dan Liu Yan Deng Tatsuo arai Masaru Kojima Xiaoming Liu Key Laboratory of Biomimetic Robots and Systems Ministry of EducationState Key Laboratory of Intelligent Control and Decision of Complex SystemBeijing Advanced Innovation Center for Intelligent Robots and Systemsand School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing 100081China Center for Neuroscience and Biomedical Engineering The University of Electro-CommunicationsTokyo 182-8585Japan Department of Materials Engineering Science Osaka UniversityOsaka 560-8531Japan

Magnetic soft microrobots have great potential to access narrow spaces and conduct multiple tasks in the biomedical *** now,drug delivery,microsurgery,disease diagnosis,and dredging the blocked blood vessel have been realized by magnetic soft microrobots in vivo or in ***,as the tasks become more and more complex,more functional units have been embedded in the body of the developed magnetic *** magnetic soft microrobots with complex designed geometries,mechanisms,and magnetic orientation are now greatly challenging the fabrication of the magnetic *** this paper,we propose a new method combining photopolymerization and assembly for the fabrication of magnetic soft *** the micro-hand assembly system,magnetic modules with different shapes and materials are firstly arrayed with precise position and orientation ***,the developed photopolymerization system is employed to fix and link these modules with soft *** on the proposed fabrication method,3 kinds of soft magnetic microrobots were fabricated,and the fundamental locomotion was *** believe that the presented fabrication strategy could help accelerate the clinical application of magnetic microrobots.

关键词： Magnetic system precise

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