检索结果-南通市图书馆

Effects of soil profile and characteristic of exciting force on propagation of ground vibrations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Modern Transportation 2012年第3期20卷 129-137页

作者： Sunao KUNIMATSU Yoshihiro HIRAO yasutoshi KITAMURA Institute for Geo-Resources and Environment National Institute of Advanced Industrial Science and Technology1-1-1 Higashi Tsukuba Ibaraki 305-8567 Japan Kobayashi Institute of Physical Research 3-20-41 Higashi-Motomachi Kokubunji Tokyo 185-0020 Japan Construction Engineering Research Institute Foundation 1-3-10 Turukabuto Nada-ku Kobe Hyogo 657-0011 Japan

Ground-borne vibrations caused by vibration sources such as road traffic and construction exhibit complicated properties during propagation from the vibration source to the inside of a building. In the present paper, a numerical analysis technique for the system of vibration source and propagation path of ground vibration is developed in order to systematically determine the propagation properties of the vibration as part of developing a predictive technique for exposure evaluations by vibrations in three directions at receiving points of vibration in the human body. First, the exciting forces in three directions for input into the numerical computation are inversely-estimated by using the measured acceleration rec- ords of the measurement points, which are near the vibration source. The thin-layered element method is used for numerical computation of the ground vibration. Then, the calculation results for the ground vibration obtained by using the estimated exciting force are compared with the measured results, and the influence of the stratified structure of the ground on the exciting force and the propagation properties of the ground vibration are studied. From these results, in a prediction of the ground vibration in three directions, it is emphasized that it is necessary to consider the influence of horizontal exciting force, although attention has been paid to only the vertical exciting force for simulating ground vibration.

关键词： ground-borne vibration vibration source exciting force stratified structure soil profile

Vascular endothelial growth factor 165b expression in stromal cells and colorectal cancer

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第44期17卷 4867-4874页

作者： Makoto Tayama Tomohisa Furuhata Yoshiko Inafuku Kenji Okita Toshihiko Nishidate Toru Mizuguchi yasutoshi Kimura Koichi Hirata the First Department of Surgery Sapporo Medical University

AIM:To characterize the implications of vascular endothelial growth factor(VEGF)-A in stromal cells and colorectal cancer and the expression of VEGF-A splice ***:VEGF-A expression in tumor and stromal cells from 165 consecutive patients with colorectal cancer was examined by *** association between VEGF-A expression status and clinicopathological factors was *** freshfrozen samples were obtained for laser capture microdissection to analyze the splice variants of ***:VEGF-A was expressed in 53.9% and 42.4% of tumor and stromal cells,***-A expression in tumor cells(t-VEGF-A) was associated with advanced clinical stage(stage 0,1/9;stage 1,2/16;stage 2,32/55;stage 3,38/66;stage 4,16/19,P < 0.0001).VEGF-A expression in stromal cells(s-VEGF-A) increased in the earlier clinical stage(stage 0,7/9;stage 1,6/16;stage 2,33/55;stage 3,22/66;stage 4,5/19;P = 0.004).Multivariate analyses for risk factors of recurrence showed that only s-VEGF-A expression was an independent risk factor for recurrence(relative risk 0.309,95% confidence interval 0.141-0.676,P = 0.0033).The five-year disease-free survival(DFS) rates of t-VEGF-A-positive and-negative cases were 51.4% and 62.9%,*** was no significant difference in t-VEGF-A expression *** five-year DFS rates of s-VEGF-A-positive and-negative cases were 73.8% and 39.9%,respectively.s-VEGFA-positive cases had significantly better survival than s-VEGF-A-negative cases(P = 0.0005).Splice variant analysis revealed that t-VEGF-A was mainly composed of VEGF165 and that s-VEGF-A included both VEGF165 and *** cases with no venous invasion(v0),the level of VEGF165b mRNA was significantly higher(v0 204.5 ± 122.7,v1 32.5 ± 36.7,v2 2.1 ± 1.7,P = 0.03).The microvessel density tended to be lower in cases with higher VEGF165b mRNA ***:s-VEGF-A appears be a good prognostic factor for colorectal cancer and includes VEGF165 and VEGF165b.

关键词： Colorectal cancer Vascular endothelial growth factor-A Vascular endothelial growth factor 165 Microvascular density Stromal cell

Assessment of liver fibrosis by a noninvasive method of transient elastography and biochemical markers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第27期12卷 4325-4330页

作者： Masaki Kawamoto Toru Mizuguchi Tadashi Katsuramaki Minoru Nagayama Hideki Oshima Hiroyuki Kawasaki Takayuki Nobuoka yasutoshi Kimura Koichi Hirata Department of Surgery Ⅰ Sapporo Medical University HospitalSapporo Medical University School of MedicineS-1W-16Chuo-KuSapporoHokkaido 060-8543Japan

AIM： To assess the correlation between the fibrotic area （FA） as calculated by a digital image analysis （DIA）, and to compare the diagnostic accuracy of FibroScan to the other existing Liver fibrosis （LF） markers using the receiver operating curve analysis.METHODS： We recruited 30 patients who underwent a liver resection for three different etiologies including normal liver, hepatitis B, and hepatitis C. Liver stiffness was measured by using a FibroScan. The FA was then calculated by DIA to evaluate LF in order to avoid any sampling bias. RESULTS： The FA negatively correlated with Prothrombin time （PT）, platelet count, lecithin-cholesterol acyltransferase （LCAT）, and pre-albumin （ALB）. On the other hand, the findings of FibroScan correlated with similar markers. The FA positively correlated with FibroScan, serum hyaluronate level, and type Ⅳ collagen level, and aspartate transaminase to platelet ratio index （APRI）. The area under the receiver operating curve for FibroScan was higher than that for the other markers, even though the statistical significance was minimal. CONCLUSION： Our findings suggest that FibroScan can initially be used to assess LF as an alternative to a liver biopsy （LB） and serum diagnosis, because it is a safe method with comparable diagnostic accuracy regarding the existing LF markers.

关键词： Cirrhosis Digital image analysis Fibro-Scan Fibrotic area Hyaluronate Lecithin-cholesterol acyltransferase Liver fibrosis Pre-albumin

Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第31期20卷 10813-10824页

作者： Daisuke Kyuno Hiroshi Yamaguchi Tatsuya Ito Tsuyoshi Kono yasutoshi Kimura Masafumi Imamura Takumi Konno Koichi Hirata Norimasa Sawada Takashi Kojima Department of Surgery Sapporo Medical University School of Medicine Department of Cell Science Research Institute for Frontier Medicine Sapporo Medical University School of Medicine Department of Pathology Sapporo Medical University School of Medicine

Pancreatic cancer continues to be a leading cause of cancer-related death worldwide and there is an urgent need to develop novel diagnostic and therapeutic strategies to reduce the mortality of patients with this disease. In pancreatic cancer, some tight junction proteins, including claudins, are abnormally regulated and therefore are promising molecular targets for diagnosis, prognosis and therapy. Claudin-4 and-18 are overexpressed in human pancreatic cancer and its precursor lesions. Claudin-4 is a high affinity receptor of Clostridium perfringens enterotoxin(CPE). The cytotoxic effects of CPE and monoclonal antibodies against claudin-4 are useful as novel therapeutic tools for pancreatic cancer. Claudin-18 could be a putative marker and therapeutic target with prognostic implications for patients with pancreatic cancer. Claudin-1,-7, tricellulin and marvelD3 are involved in epithelial to mesenchymal transition(EMT) of pancreatic cancer cells and thus might be useful as biomarkers during disease. Protein kinase C is closely related to EMT of pancreatic cancer and regulates tight junctions of normal human pancreatic duct epithelial cells and the cancer cells. This review focuses on the regulation of tight junctions via protein kinase C during EMT in human pancreatic cancer for the purpose of developing new diagnostic and therapeutic modalities for pancreatic cancer.

关键词： Tight junctions Claudins Tricellulin MarvelD3 Normal human pancreatic duct epithelial cells Pancreatic cancer Protein kinase C Epithelial to mesenchymal transition

Treatment strategy for pancreatic head cancer with celiac axis stenosis in pancreaticoduodenectomy:A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第8期28卷 868-877页

作者： Eiji Yoshida yasutoshi Kimura Takuro Kyuno Ryoko Kawagishi Kei Sato Tsuyoshi Kono Takehiro Chiba Toshimoto Kimura Hitoshi Yonezawa Osamu Funato Makoto Kobayashi Kenji Murakami Akinori Takagane Ichiro Takemasa Department of Surgery Hakodate Goryoukaku HospitalHakodate City 040-8611Japan Department of Surgery Surgical Oncology and ScienceSapporo Medical UniversitySapporo City 060-8543HokkaidoJapan Department of Diagnostic Radiology Hakodate Goryoukaku HospitalHakodate City 040-8611Japan

BACKGROUND During pancreaticoduodenectomy in patients with celiac axis(CA)stenosis due to compression by the median arcuate ligament(MAL),the MAL has to be divided to maintain hepatic blood flow in many ***,MAL division often fails,and success can only be determined *** overcome this problem,we performed endovascular CA stenting preoperatively,and thereafter safely performed *** present this case as a new preoperative treatment strategy that was *** SUMMARY A 77-year-old man with a diagnosis of pancreatic head cancer presented to our department for *** assessment revealed CA stenosis caused by *** performed endovascular stenting in the CA preoperatively because we knew that going into the operation without a strategy could lead to ischemic ***-antiplatelet therapy(DAPT)–which is needed when a stent is inserted–was then administered in parallel with neoadjuvant chemotherapy(NAC).This allowed us to administer DAPT for a sufficient period before the main pancreaticoduodenectomy procedure while obtaining therapeutic effects from *** stomach-preserving pancreaticoduodenectomy was *** operation did not require any unusual techniques and was performed ***,the patient progressed well,without any ischemic ***,curative resection was confirmed,and the patient had no recurrence or complications due to ischemia up to six months *** Preoperative endovascular stenting,with NAC and DAPT,is effective and safe prior to pancreaticoduodenectomy in potentially resectable pancreatic cancer.

关键词： Pancreaticoduodenectomy Celiac axis stenosis Median arcuate ligament Endovascular stenting Pancreatic head cancer Case report

Progression of remnant gastric cancer is associated with duration of follow-up following distal gastrectomy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第22期18卷 2832-2836页

作者： Shuhei Komatsu Daisuke Ichikawa Kazuma Okamoto Daito Ikoma Masahiro Tsujiura Yukihisa Nishimura yasutoshi Murayama Atsushi Shiozaki Hisashi Ikoma Yoshiaki Kuriu Masayoshi Nakanishi Hitoshi Fujiwara Toshiya Ochiai Yukihito Kokuba Eigo Otsuji Division of Digestive Surgery Department of Surgery Kyoto Prefectural University of Medicine 465 Kajii-cho Kawaramachihirokoji Kamigyo-ku Kyoto 602-8566 Japan

AIM： TO re-evaluate the recent clinicopathological fea- tures of remnant gastric cancer （RGC） and to develop desirable surveillance ***： Between 1997 and 2008, 1149 patients underwent gastrectomy for gastric cancer at the Department of Digestive Surgery, Kyoto Prefectural Uni- versity of Medicine, Japan. Of these, 33 patients un- derwent gastrectomy with lymphadenectomy for RGC. Regarding the initial gastric disease, there were 19 patients with benign disease and 14 patients with gas- tric cancer. The hospital records of these patients were reviewed retrospectively. RESULTS： Concerning the initial gastric disease, the RGC group following gastric cancer had a shorter in- terval [P 〈 0.05; gastric cancer vs benign disease： 12 （2-22） vs 30 （4-51） years] and were more frequently reconstructed by Billroth- I procedure than those fol- lowing benign lesions （P 〈 0.001）. Regarding recon- struction, RGC following Billroth-]_l reconstruction showed a longer interval between surgical procedures [P 〈 0.001; Billroth-11 vs Billroth- I ： 32 （5-51） vs 12 （2-36） years] and tumors were more frequently associated with benign disease （P 〈 0.001） than those following Billroth- I reconstruction. In tumor location of RGC, after Billroth- I reconstruction, RGC occurred more fre- quently near the suture line and remnant gastric wall. After Billroth- 1I reconstruction, RGC occurred more fre- quently at the anastomotic site. The duration of follow- up was significantly associated with the stage of RGC （P 〈 0.05）. Patients diagnosed with early stage RGC such as stage Ⅰ-Ⅱ tended to have been followed up almost every second year. CONCLUSION： Meticulous follow-up examination and early detection of RGC might lead to a better prognosis. Based on the initial gastric disease and the procedure of reconstruction, an appropriate follow-up interval and programs might enable early detection of RGC.

关键词： Remnant gastric cancer Surveillance Fol-low-up Reconstruction Distal gastrectomy

Early thrombomodulin-α administration outcome for acute disseminated intravascular coagulopathy in gastrointestinal surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第5期23卷 891-898页

作者： Hirotaka Konishi Kazuma Okamoto Katsutoshi Shoda Tomohiro Arita Toshiyuki Kosuga Ryo Morimura Shuhei Komatsu yasutoshi Murayama Atsushi Shiozaki Yoshiaki Kuriu Hisashi Ikoma Masayoshi Nakanishi Daisuke Ichikawa Hitoshi Fujiwara Eigo Otsuji Division of Digestive Surgery Department of SurgeryKyoto Prefectural University of MedicineKajii-choKyoto city 6028566Japan

AIMTo investigate the efficacy of thrombomodulin (TM)-α for treatment of disseminated intravascular coagulopathy (DIC) in the field of gastrointestinal ***-six peri-operative DIC patients in the field of gastrointestinal surgery who were treated with TM-α were retrospectively investigated. The relationships between patient demographics and the efficacy of TM-α were examined. Analysis of survival at 28 d was also performed on some parameters by means of the Kaplan-Meier method. Relationships between the initiation of TM-α and patient demographics were also *** formation or bacteremia was the most frequent cause of DIC (33%), followed by digestive tract perforation (31%). Twenty-six patients developed DIC after surgery, frequently within 1 wk (81%). TM-α was most often administered within 1 d of the DIC diagnosis (72%) and was continued for more than 3 d (64%). Although bleeding tendency was observed in 7 patients (19%), a hemostatic procedure was not needed. DIC scores, systemic inflammatory response syndrome (SIRS) scores, quick-sequential organ failure assessment (qSOFA) scores, platelet counts, and prothrombin time ratios significantly improved after 1 wk (P < 0.05, for all). The overall survival rate at 28 d was 71%. The duration of TM-α administration (≥ 4 , ≤ 6) and improvements in DIC-associated scores (DIC, SIRS and qSOFA) at 1 wk were significantly better prognostic factors for 28-d survival (P < 0.05, for all). TM-α was administered significantly earlier to patients with severe clinical symptoms, such as high qSOFA scores, sepsis, shock or high lactate values (P < 0.05, for all).CONCLUSIONEarly administration of TM-α and improvements in each parameter were essential for treatment of DIC. The diagnosis of patients with mild symptoms requires further study.

关键词： Quick-sequential organ failure assessment Thrombomodulin-α Gastrointestinal surgery Systemic inflammatory response syndrome Acute disseminated intravascular coagulopathy

Characterization of Microcrystalline Germanium Carbon Thin Films-A Novel Absorber Material for PV Applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Characterization of Microcrystalline Germanium Carbon Thin F...

Vietnam’s Future Water Usage Model: A Controlled Living Experiment

第十五届国际光伏科学与工程大会

作者： yasutoshi Yashiki Shinsuke Miyajima Akira Yamada Makoto Konagai Department of Physical Electronics Tokyo Institute of Technology Quantum Nanoelectronics Research Center Tokyo Institute of Technology 2-12-1-S9-9O-okayamaMeguro-kuTokyo 152-8552Japan

Thin films of amorphous germanium carbon (a-GeC) and microcrystalline germanium carbon (μc-GeC) were deposited by Hotwire CVD technque. Monomethylgermane and hydrogen were used as source gases during the deposition of these films. Optical properties of these films were characterized by photothermal deflection spectroscopy. Optical absorption spectra of a-GeC and μc-GeC thin films shifted up to the higher energy side compared with amorphous germanium and crystal germanium. The Tauc gap of a-GeC thin films is found to be 1.45 eV, and the absorption spectra of μc-GeC thin films is shifted up by 0.3 eV. The Urbach energy of a-GeC and μe-GeC films are found to be 82meV and 79meV, respectively.

关键词： Germanium carbon Hot wire chemical vapor deposition Optical property

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Water Resource and Protection 2018年第2期10卷 204-214页

作者： Kanako Toyosada Takayuki Otani yasutoshi Shimizu Hiroshi Takata Kazuhiko Sakamoto Saburo Murakawa Shunsuke Managi Department of Environmental Science Fukuoka Women’s University Fukuoka Japan ESG Promotion Department TOTO Ltd. Fukuoka Japan Urban Institute & Departments of Urban and Environmental Engineering Kyushu University Fukuoka Japan Water and Lifestyle Research Laboratory Fukuoka Japan Graduate School of Education Hiroshima University Hiroshima Japan Department of Architecture Okayama University of Science Okayama Japan Hiroshima University Hiroshima Japan

The purpose of this study was to explore the water usage profile of future Vietnamese households by carrying out a controlled living experiment with Vietnamese high-income households. By studying showering time, flow rate and toilet-use frequency of these households, the study revealed the water usage believed to be representative of future households in light of continued urbanization. This study also determined that the average time of showering was 9.7 minutes per person per day with an average flow rate of 12 L/minute for the existing shower head and 6.6 L/minute for the water-saving shower head. Toilet usage frequency was 5.25 times per person per day, and there was no difference with the results for an average (middle-income) household.

关键词： Water-Saving Equipment Water Usage Controlled Living Experiment Vietnamese Household