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World Journal of Gastroenterology 2012年第16期18卷 1926-1932页

作者： Hideki Fujii Yoshito Itoh Naoki Ohnishi Masafumi Sakamoto Tohru Ohkawara Yoshihiko Sawa Koichi Nishida yasuo Ohkawara Kanji Yamaguchi Masahito Minami Takeshi Okanoue Department of Internal Medicine Aiseikai Yamashina HospitalKyoto 602-8566Japan Molecular Gastroenterology and Hepatology Kyoto Prefectural University of MedicineGraduate School of Medical ScienceKyoto 602-8566Japan Hepatology Center Saiseikai Suita HospitalOsaka 564-0013Japan

AIM:To identify the factors associated with overall survival of elderly patients with hepatocellular carcinoma(HCC).METHODS:A total of 286 patients with HCC(male/female:178/108,age:46-100 years),who were diagnosed and treated by appropriate therapeutic procedures between January 2000 and December 2010,were enrolled in this *** were stratified into two groups on the basis of age:Elderly(≥ 75 years old) and non-elderly(< 75 years old).Baseline clinical characteristics as well as cumulative survival rates were then compared between the two *** and multivariate analyses were used to identify the factors associated with prolonged overall survival of patients in each *** survival rates in the two groups were calculated separately for each modified Japan Integrated Stage score(mJIS score) category by the Kaplan-Meier *** addition,we compared the cumulative survival rates of elderly and non-elderly patients with good hepatic reserve capacity(≤ 2 points as per mJIS).RESULTS:In the elderly group,the proportion of female patients,patients with absence of hepatitis B or hepatitis C viral infection,and patients with coexisting extrahepatic comorbid illness was higher(56.8% vs 31.1%,P < 0.001;27.0% vs 16.0%,P = 0.038;33.8% vs 22.2%,P = 0.047;respectively) than that in the nonelderly *** the non-elderly group,the proportion of hepatitis B virus(HBV)-infected patients was higher than that in the elderly group(9.4% vs 0%,P = 0.006).The cumulative survival rates in the elderly group were 53.7% at 3 years and 32.9% at 5 years,which were equivalent to those in the non-elderly group(55.9% and 39.4%,respectively),as shown by a log-rank test(P = 0.601).In multivariate analysis,prolonged survival was significantly associated with the extent of liver damage and stage(P < 0.001 and P < 0.001,respectively),but was not associated with patient ***,on individual evaluation of factors in both groups,stage was significantly(P < 0.001) associ

关键词： Age Hepatocellular carcinoma Liver damage Stage Survival

利用ISSR标记进行菜用大豆和普通大豆的分类

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大豆科学 2008年第5期27卷 732-739页

作者：谢甫绨 Takahata Yoshihito Ohno yasuo 沈阳农业大学农学院辽宁沈阳110161 Faculty of Agriculture lwate University020-8550Japan Sato Masayuki Seed Co. Yahabacho 02-0891Japan

ISSR标记技术因具有很高的多肽性而被广泛应用于遗传多样性研究。进行菜用大豆品种多样性研究将有助于育种家进行杂交亲本的合理选配。采用ISSR标记技术对37个菜用大豆品种（系）和13个普通大豆品种（系）进行了分类研究。结果表明：50... 详细信息

ISSR标记技术因具有很高的多肽性而被广泛应用于遗传多样性研究。进行菜用大豆品种多样性研究将有助于育种家进行杂交亲本的合理选配。采用ISSR标记技术对37个菜用大豆品种（系）和13个普通大豆品种（系）进行了分类研究。结果表明：50个ISSR引物中有11个引物没有多肽性，其他39个引物共产生132条谱带，其中81条多肽性谱带，占61．4％。引物扩增的谱带数在1—7条之间，大小为830—3530bp．每个引物平均扩增的谱带数和多肽性带数分别为3．3和2．1。聚类分析结果表明，可将供试的50个品种划分为3个类组，扁茎大豆Taikadaizu单独一组，7个普通大豆（多数为中国选育）划归为B组，C组由日本菜用大豆和4个普通大豆组成。C组还可以划分成若干亚组，同一亚组的品种具有相似的性状，比如有一亚组的品种均是褐脐、茶色种皮、白花、不易炸荚。系选的品种和原始品种在分类图中也显示出其密切的亲缘关系。基于ISSR标记的分类可以反映菜用大豆的遗传关系，菜用大豆和普通大豆之间存在遗传多样性，合理保存菜用大豆种质将有助于未来大豆品质改良计划。

关键词：大豆 ISSR标记多样性

Formation of Gel-Like Shear-Induced Structure with Dosing of Dilute Surfactant Solution and Its Effect on Turbulent Channel Flow

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Open Journal of Fluid Dynamics 2022年第3期12卷 249-262页

作者： Shumpei Hara Kazuki Ishii yasuo Kawaguchi Department of Mechanical Engineering Doshisha University Kyoto Japan Department of Mechanical Engineering Tokyo University of Science Chiba Japan

A shear-induced structure (SIS) is formed under appropriate concentration and shear conditions in a surfactant micellar solution. In this study, we performed experiments of surfactant solution dosing in a fully developed two-dimensional turbulent channel flow from a sintered metallic wire mesh plate attached to a side wall. We investigated the behavior of the solution under the elongation during its passing through the wire mesh and under the strong shear due to the channel flow. It was confirmed that the dosed solution containing a laser dye was visualized by a laser sheet, and the accumulated gel from the wire mesh formed a layer and developed with time. Consequently, on dosing the dilute surfactant solution from the wire mesh, a gel-like SIS layer was formed, which majorly covered the wire mesh plate. The gel-like SIS layer on the wire mesh plate acted as a sticky solid and restricted the flow in the channel. This layer continued to grow while dosing, owing to which the pressure drop of the channel flow significantly increased. The gel-like SIS layer grew rapidly even in the turbulent flow and reached the equilibrium thickness. After the termination of the dosing, the gel layer collapsed gradually. In addition, the thickness of the gel-like SIS layer (indicating the strength indirectly) strongly depended on the surfactant concentration and the elongation rate in the wire mesh.

关键词： Turbulent Channel Flow Viscoelastic Fluid Gelation Scalar Transfer PIV/PLIF

Study on the Shear Effect on Dye Patches Diffused in Wall-Bounded Shear Flow

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Open Journal of Fluid Dynamics 2016年第4期6卷 438-452页

作者： Qianqian Shao Takahiro Tsukahara yasuo Kawaguchi Department of Mechanical Engineering Tokyo University of Science Chiba Japan

This paper focuses on the high intensity filaments (dye patches) embedded in dye plumes in a wall-bounded shear flow, to investigate the shear effect on the dye patch distribution. Motivated by the widely concerned inverse estimation of the source location, we try extracting useful information to know the source location from down-stream dye patches. Accordingly, we changed the dye injection location at different distances from the wall and made observations at different downstream (diffusion) distances from the source. The orientation angle and roundness of dye patches were concerned to examine the shear effect and dye patch characteristics. To capture the dye plume images, a planar laser induced fluorescence (PLIF) technique was used. The orientation and roundness of each dye patch were calculated by least-square fitting. The statistics of both the orientation angle and the roundness were compared with those in homogeneous turbulent cases to reveal the shear effect. Different from uniformly-orientated dye patches in the homogeneous flow, larger occurrence probabilities with positive orientation angles of dye patches are observed in wall-bounded shear flow, in particular, when the injection location is near the wall. As with information extraction for the inverse estimation of source location, it is found that the orientation distribution of dye patches is independent of the diffusion distance, but related with the injection location from the wall. While for the homogeneous flow cases, a strong dependence on the diffusion distance is observed in the orientation distribution profiles. As for the roundness, similar aspects are found regarding the dependencies on the injection location in shear flow and on diffusion distance in homogeneous flow.

关键词： Dye Patch Image Processing Inverse Problem Least-Square Fitting Passive Scalar Shear Flow Source Estimation Point-Source Diffusion Wall Turbulence

Life prognosis of sentinel node navigation surgery for early-stage gastric cancer:Outcome of lymphatic basin dissection

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World Journal of Gastroenterology 2021年第46期27卷 8010-8030页

作者： Shinichi Kinami Naohiko Nakamura Tomoharu Miyashita Hidekazu Kitakata Sachio Fushida Takashi Fujimura yasuo Iida Noriyuki Inaki Toru Ito Hiroyuki Takamura Department of Surgical Oncology Kanazawa Medical UniversityKahoku 920-0293IshikawaJapan Department of Gastroenterological Endoscopy Kanazawa Medical UniversityKahoku 920-0293IshikawaJapan Department of Gastrointestinal Surgery Kanazawa UniversityKanazawa 920-8641IshikawaJapan Department of Surgery Toyama City HospitalToyama 939-8511ToyamaJapan Department of Mathematics Division of General EducationKanazawa Medical UniversityKahoku 920-0293IshikawaJapan

BACKGROUND Lymphatic basin dissection is a sentinel node biopsy method that is specific for gastric *** this method,the dyed lymphatic system is dissected en bloc,and sentinel nodes are identified at the back table(ex vivo).Even with lymphatic basin dissection,blood flow to the residual stomach can be preserved,and functionpreserving curative gastrectomy can be *** oncological safety of function-preserving curative gastrectomy combined with lymphatic basin dissection has not yet been fully *** hypothesized that the oncological safety of sentinel node navigation surgery(SNNS)is not inferior to that of the *** To investigate the life prognosis of SNNS for gastric cancer in comparison with guidelines *** This was a retrospective cohort *** were selected from gastric cancer patients who underwent sentinel node biopsy from April 1999 to March *** from April 1999 to August 2008 were from the Department of Surgery II,Kanazawa University Hospital,and patients from August 2009 to March 2016 were from the Department of Surgical Oncology,Kanazawa Medical University *** who were diagnosed with gastric cancer,which was preoperatively diagnosed as superficial type(type 0),5 cm or less in length,clinical T1-2 and node negative,and underwent various gastrectomies guided by sentinel node navigation were retrospectively *** overall survival(OS)and relapsefree survival(RFS)of these patients(SNNS group)were *** with gastric cancer of the same stage and who underwent guidelines gastrectomy with standard nodal dissection were also selected as the control *** A total of 239 patients in the SNNS group and 423 patients in the control group were *** nodal metastasis was observed in 10.5%and 10.4%of the SNNS and control groups,*** diagnostic abilities of sentinel node biopsy were 84%and 98.6%for sensitivity and accuracy,*** the

关键词： Early gastric cancer Sentinel node biopsy Function preserving surgery Lymph node dissection Gastrectomy Lymphatic basin dissection

CT/^(99m)Tc-GSA SPECT fusion images demonstrate functional differences between the liver lobes

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World Journal of Gastroenterology 2013年第21期19卷 3217-3225页

作者： Tatsuaki Sumiyoshi yasuo Shima Ryoutarou Tokorodani Takehiro Okabayashi Akihito Kozuki Yasuhiro Hata Yoshihiro Noda Yoriko Murata Toshio Nakamura Kiminori Uka Department of Gastroenterological Surgery Kochi Health Sciences CenterIke 2125KochiJapan Department of Radiology Kochi Health Sciences CenterIke 2125KochiJapan Department of Gastroenterology Kochi Health Sciences CenterIke 2125KochiJapan

AIM: To evaluate the functional differences between the 2 liver lobes in non-cirrhotic patients by using computed tomography/99mTc-galactosyl human serum albumin (CT/99mTc-GSA) single-photon emission computed tomography (SPECT) fusion images. METHODS: Between December 2008 and March 2012, 264 non-cirrhotic patients underwent preoperative liver function assessment using CT/99mTc-GSA SPECT fusion images. Of these, 30 patients, in whom the influence of a tumor on the liver parenchyma was estimated to be negligible, were selected. Specifically, the selected patients were required to meet either of the following criteria: (1) the presence of an extrahepatic tumor; or (2) presence of a single small intrahepatic tumor. These 30 patients were retrospectively analyzed to calculate the percentage volume (%Volume) and the percentage function (%Function) of each lobe. The ratio between the %Function and %Volume (function-to-volume ratio) of each lobe was also calculated, and the ratios were compared between the 2 lobes. Furthermore, the correlations between the function-to-volume ratio and each of 2 liver parameters [lobe volume and diameter ratio of the left portal vein to the right portal vein (LPV-to-RPV diameter ratio)] were investigated. RESULTS: The median values of %Volume and %Function were 62.6% and 67.1% in the right lobe, with %Function being significantly higher than %Volume (P < 0.01). The median values of %Volume and %Function were 31.0% and 28.7% in the left lobe, with %Function being significantly lower than %Volume (P < 0.01). The function-to-volume ratios of the right lobe (1.04-1.14) were significantly higher than those of the left lobe (0.74-0.99) (P < 0.01). The function-to-volume ratio showed no significant correlation between the lobe volume in either lobe. In contrast, the function-to-volume ratio showed significant correlations with the LPV-to-RPV diameter ratio in both lobes (right lobe: negative correlation, rs = -0.37, P = 0.048; left lobe: positive

关键词： Computed tomography 99mTc neogalactoalbumin Single-photon emission computed tomography Fusion image Liver Portal system

Thermally activated delayed fluorescence carbazole-triazine dendrimer with bulky substituents

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Aggregate 2024年第1期5卷 236-243页

作者： Hiroki Ikebe Kohei Nakao Eri Hisamura Minori Furukori yasuo Nakayama Takuya Hosokai Minlang Yang Guanting Liu Takuma Yasuda Ken Albrecht Interdisciplinary Graduate School of Engineering Sciences Kyushu UniversityFukuokaJapan Institute for Materials Chemistry and Engineering Kyushu UniversityKasugaJapan Department of Pure and Applied Chemistry Graduate School of Science and TechnologyTokyo University of ScienceNodaChibaJapan National Metrology Institute of Japan(NMIJ) National Institute of Advanced Industrial Science and Technology(AIST)TsukubaIbarakiJapan Institute for Advanced Study Kyushu UniversityNishi-kuFukuokaJapan

Carbazole-triazine dendrimers with a bulky terminal substituent were synthesized,and the thermally activated delayed fluorescence(TADF)property was *** to unsubstituted carbazole dendrimers,dendrimers with bulky terminal substituents showed comparable to better photoluminescence quantum yields(PLQY)in neat ***(PF)-substituted dendrimers showed the highest PLQY of 81%,a smallΔEst of 0.06 eV,and the fastest reverse intersystem crossing(RISC)rate of∼1×10^(5 )s^(−1) compared to other *** measurements of dendrimers and dendrons(fragments)indicate that the close proximity of the triplet energy of phenylfluorene-substituted carbazole dendrons(^(3)LE)to that of phenylfluorene-substituted dendrimers(^(1)CT,^(3)CT)contributes to RISC promotion and improves TADF *** modification fine-tunes the energy level and suppresses intermolecular interactions,and this study provides a guideline for designing efficient solution-processable and non-doped TADF materials.

关键词： dendrimer OLED TADF 1 INTRODUCTION Thermally activated delayed fluorescence(TADF)materials which are inexpensive and highly efficient alternatives to fluorescent

新疆阿尔泰山南部富蕴右旋走滑断裂带晚第四纪错断水系的遥感分析研究

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第四纪研究 2008年第2期28卷 273-279页

作者：张之武付碧宏 yasuo Awata 中国科学院青藏高原研究所北京100085 中国科学院地质与地球物理研究所北京100029 日本经济产业省产业技术综合研究所日本筑波305-8567

富蕴断裂带位于阿尔泰山南侧，横切阿尔泰山褶皱带南缘及额尔齐斯深断裂，是一条呈北北西向展布的右旋走滑断裂带。沿断裂带发育一系列错断水系、错断冲积扇、挤压脊、走滑拉分盆地等反映右旋走滑活动的典型构造地貌标志。本研究在高分... 详细信息

富蕴断裂带位于阿尔泰山南侧，横切阿尔泰山褶皱带南缘及额尔齐斯深断裂，是一条呈北北西向展布的右旋走滑断裂带。沿断裂带发育一系列错断水系、错断冲积扇、挤压脊、走滑拉分盆地等反映右旋走滑活动的典型构造地貌标志。本研究在高分辨率遥感图像和数字高程模型分析的基础上，结合野外实地构造地貌测量，对沿富蕴断裂带发育的系统错断水系特征进行了详细分析研究。研究结果表明，沿富蕴断裂带发育不同级别的错断水系，大致可划分为6级：1931年地震形成的冲沟；90m左右断距的错断水系；150m左右断距的错断水系；500m左右断距的错断水系；1500m左右断距的错断水系；2000m以上断距的错断水系。同时，结合研究区及邻区的第四纪冰川资料讨论了不同级别水系可能形成时间：恰尔沟三级支流可能形成时间为末次冰期Ⅲ阶段末期，约20ka；恰尔沟二级支流可能形成时间为末次冰期Ⅰ阶段末期，约120ka；恰尔沟一级支流可能形成于该地区冰川广泛消融的倒数第2次冰期的Ⅱ阶段末期，约为250ka；恰尔沟、水磨沟、白杨沟、乌铁布拉克河、卡布尔特河等可能形成于倒数第3次冰期Ⅱ阶段末期，约为360ka。最后，我们估算出富蕴断裂带晚第四纪以来的平均右旋走滑速率为1．46—4．99mm／a。

关键词：右旋走滑走滑速率系统水系错断富蕴断裂带阿尔泰山

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Journal of Signal and Information Processing 2018年第2期9卷 73-91页

作者： Teruki Horie Masato Uchida yasuo Matsuyama Department of Computer Science and Engineering Waseda University Tokyo Japan Faculty of Science and Engineering Waseda University Tokyo Japan

In this paper, we present machine learning algorithms and systems for similar video retrieval. Here, the query is itself a video. For the similarity measurement, exemplars, or representative frames in each video, are extracted by unsupervised learning. For this learning, we chose the order-aware competitive learning. After obtaining a set of exemplars for each video, the similarity is computed. Because the numbers and positions of the exemplars are different in each video, we use a similarity computing method called M-distance, which generalizes existing global and local alignment methods using followers to the exemplars. To represent each frame in the video, this paper emphasizes the Frame Signature of the ISO/IEC standard so that the total system, along with its graphical user interface, becomes practical. Experiments on the detection of inserted plagiaristic scenes showed excellent precision-recall curves, with precision values very close to 1. Thus, the proposed system can work as a plagiarism detector for videos. In addition, this method can be regarded as the structuring of unstructured data via numerical labeling by exemplars. Finally, further sophistication of this labeling is discussed.

关键词： Similar Video Retrieval Exemplar Learning M-Distance Sequence Alignment Data Structuring