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第三届亚洲机械电子学学术会议

作者： yasuhito yoshizawa Shunji Shimizu Nobuhide Hirai Fumikazu Miwakeichi Senichiro Kikuchi Hironori Tedzuka Eiju Watanabe Graduate School of Engineering Management Tokyo University of Science Suwa Tokyo University of Science Suwa Department of Psychiatry Jichi Medical University Faculty of Engineering Chiba University Graduate School of Engineering Management Tokyo University of Science Suwa

There have been numerous single-channel measurements performed in one area of the prefrontal cortex regarding brain activity while driving.[1]The steering action while driving a vehicle is simulated,and the seated subjects move each of their hands in a clockwise and counterclockwise circular motion. Simultaneously,the brain act ivity of the subjects was measured using near infrared spectroscopy(NIRS).Since the optic pathways in the brain process information using two pathways,a ventral(objects’shape and color)and dorsal(movement and position)pathway, which are believed to be integrated in the prefrontal cortex of the frontal lobe,the area we measured was the area in the vicinity of the prefrontal cortex of the frontal *** details regarding the circular movement include holding a mouse at a desk,and drawing a circle with a diameter of about 30 *** circles are drawn at a pace of about one circle every four seconds,with the measurements taken over a durat ion of 20 s(total 5 circles).The measurement intervals consist of a 10-s break, the 20-s task,followed by another 10-s break, repeated over 5 *** subjects used in our study were all right-handed males in their twent ies who had a histor y of driving.

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Classifying genotype F of hepatitis B virus into F1 and F2 subtypes

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World Journal of Gastroenterology 2005年第40期11卷 6295-6304页

作者： Hideaki Kato Kei Fujiwara Robert G. Gish Hiroshi Sakugawa Hiroshi yoshizawa Fuminaka Sugauchi Etsuro Orito Ryuzo Ueda yasuhito Tanaka Takanobu Kato Yuzo Miyakawa Masashi Mizokami Department of Internal Medicine and Molecular Science Hepatology and Gastroenterology First Department of Medicine Department of Epidemiology and Control of Infectious Diseases Department of Clinical Molecular Informative Medicine Miyakawa Memorial Research Foundation

AIM: To explore the propriety of providing hepatitis B virus(HBV) genotypes F and H with two distinct ***: Eleven HBV isolates of genotype F (HBV/F)were recovered from patients living in San Francisco,Japan, Panama, and Venezuela, and their full-length sequences were determined. Phylogenetic analysis was carried out among them along with HBV isolates previously ***: Seven of them clustered with reported HBV/F isolates in the phylogenetic tree constructed on the entire genomic sequence. The remaining four flocked on another branch along with three HBV isolates formerly reported as genotype H. These seven HBV isolates, including the four in this study and the three reported, had a sequence divergence of 7.3-9.5% from the other HBV/F isolates,and differed by ＞ 13.7% from HBV isolates of the other six genotypes (A-E and G). Based on a marked genomic divergence, falling just short of ＞8% separating the seven genotypes, these seven HBV/F isolates were classified into F2 subtype and the former seven into F1 subtype provisionally. In a pairwise comparison of the S-gene sequences among the 7 HBV/F2 isolates and against 47HBV/F1 isolates as well as 136 representing the other six genotypes (A-E and G), two clusters separated by distinct genetic distances ***: Based on these analyses, classifying HBV/F isolates into two subtypes (F1 and F2) would be more appropriate than providing them with two distinct genotypes (F and H).

关键词：基因型F 乙型肝炎病毒病毒类型病毒感染

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