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Efficacy and safety of distal radial approach for cardiac catheterization: A systematic review and meta-analysis

World Journal of Cardiology 2021年第5期13卷 144-154页

作者： Toshihide Izumida Jun Watanabe Ryo Yoshida Kazuhiko kotani Division of Community Medicine Kanazawa Medical University Himi Municipal HospitalHimi 935-8531ToyamaJapan Center for Community Medicine Jichi Medical UniversityShimotsuke-City 329-0498TochigiJapan Department of Internal Medicine Iwami HospitalIwami-Town 681-0003TottoriJapan

BACKGROUND The traditional radial approach(RA)is recommended as the standard method for coronary angiography(CAG),while a distal RA(DRA)has been recently used for *** To assess the efficacy and safety of the DRA vs RA during *** The following databases were searched through December 2020:MEDLINE,the Cochrane Central Register of Controlled Trials,EMBASE,the World Health Organization International Clinical Trials Platform Search Portal,and *** randomized-controlled trials for adult patients undergoing cardiac catheterization were *** primary outcomes were the successful cannulation rate and the incidence of radial artery spasm(RAS)and radial artery occlusion(RAO).Study selection,data abstraction and quality assessment were independently performed using the Grading of Recommendations,Assessment,Development,and Evaluation *** Three randomized control trials and 13 registered trials were *** two approaches showed similar successful cannulation rates[risk ratio(RR)0.90,95%confidence interval(CI):0.72-1.13].The DRA did not decrease RAS(RR 0.43,95%CI:0.08-2.49)and RAO(RR 0.48,95%CI:0.18-1.29).Patients with the DRA had a shorter hemostasis time in comparison to those with the RA(mean difference-6.64,95%CI:-10.37 to-2.90).The evidence of certainty was *** For CAG,the DRA would be safer than the RA with comparable cannulation *** the limited data,additional research,including studies with standard protocols,is necessary.

关键词： Radial artery Cardiac catheterization Coronary angiography Snuff box Systematic review Meta-analysis

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Spectral Problems of Ergodic Schrodinger Operators

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应用概率统计 2015年第6期31卷 596-661页

作者： SHINICHI kotani Osaka University Osaka Japan 565-0871

本文介绍一维Schrdinger算子的谱理论.主要讨论作者所得到的定理,并给出了详细证明.

关键词：数学概率分析函数

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Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: A case report

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World Journal of Gastroenterology 2005年第34期11卷 5394-5397页

作者： Hiroki Oikawa Chihaya Maesawa Ryo Sato Kanta Oikawa Hiroyuki Yamada Seizo Oriso Sadahide Ono Akiko Yashima-Abo Koji kotani Kazuyuki Suzuki Tomoyuki Masuda Department of Pathology Iwate Medical University School of Medicine Morioka Japan Department of Internal Medicine I Iwate Medical University School of Medicine Morioka Japan Department of Internal Medicine Iwate Prefectural Ninohe Hospital Ninohe Japan Department of Pathology Iwate Prefectural Central Hospital Morioka Japan

The anti-arrhythmic agent amiodarone （AD） is associated with numerous adverse effects, but serious liver disease is rare. The improved safety of administration of daily low doses of AD has already been established and this regimen is used for long-term medication. Nevertheless, asymptomatic continuous liver injury by AD may increase the risk of step-wise progression of non-alcoholic fatty liver disease. We present an autopsy case of AD-induced liver cirrhosis in a patient who had been treated with a low dose of AD （200 rag/d） daily for 84 too. The patient was a 85-year-old male with a history of ischemic heart disease. Seven years after initiation of treatment with AD, he was admitted with cardiac congestion. The total dose of AD was 528 g. Mild elevation of serum aminotransferase and hepatomegaly were present. Liver biopsy specimens revealed cirrhosis, and under electron microscopy numerous lysosomes with electron-dense, whorled, lamellar inclusions characteristic of a secondary phospholipidosis were observed. Initially, withdrawal of AD led to a slight improvement of serum aminotransferase levels, but unfortunately his general condition deteriorated and he died from complications of pneumonia and renal failure. Long-term administration of daily low doses of AD carries the risk of progression to irreversible liver injury. Therefore, periodic examination of liver function and/or liver biopsy is required for the management of patients receiving long-term treatment with AD.

关键词： Amiodarone Liver cirrhosis NASH NAFLD Liver biopsy

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Natural history of major complications in hepatitis C virus-related cirrhosis evaluated by per-rectal portal scintigraphy

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World Journal of Gastroenterology 2005年第25期11卷 3882-3886页

作者： Etsushi Kawamura Daiki Habu Takehiro Hayashi Ai Oe Jin kotani Hirotaka Ishizu Kenji Torii Joji Kawabe Wakaba Fukushima Takashi Tanaka Shuhei Nishiguchi Susumu Shiomi Department of Nuclear Medicine Department of Hepatology Department of Public Health

AIM: To examine the correlation between the porto-systemic hypertension evaluated by portal shunt index (PSI) and life-threatening complications, including hepatocellular carcinoma (HCC), liver failure (Child-Pugh stage progression), and esophagogastric varices. METHODS: Two hundred and twelve consecutive subjects with HCV-related cirrhosis (LC-C) underwent per-rectal portal scintigraphy. They were allocated into three groups according to their PSI: group Ⅰ, PSI≤10%; group Ⅱ, 10%

关键词： Portal shunt index Porto-systemic shunting Per-rectal portal sdntigraphy Natural history Liver cirrhosis HCV Hepatocellular carcinoma Liver failure Varix

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Estimation of the Antioxidant Activities of Flavonoids from Their Oxidation Potentials

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中国实验方剂学杂志 2002年第S1期8卷 -页

作者： Kensuke ARAI Fumiyo KUSU Akira kotani School of Pharmacy Tokyo University of Pharmacy and Life Science Tokyo University of Pharmacy and Life Science 14321Horinouchi Hachioji Tokyo192-0392 Japan 14321Horinouc

Ａｓｉｍｐｌｅｅｌｅｃｔｒｏｃｈｅｍｉｃａｌｍｅｔｈｏｄｆｏｒｅｓｔｉｍａｔｉｎｇｔｈｅａｎｔｉｏｘｉｄａｎｔａｃｔｉｖｉｔｙ (ＡＡ)ｏｆｆｌａｖｏｎｏｉｄｓｈａｓｂｅｅｎｄｅｖｅｌｏｐｅｄ .Ｔｈｅｐｒｏｐｏｓｅｄｍ...

Ａｓｉｍｐｌｅｅｌｅｃｔｒｏｃｈｅｍｉｃａｌｍｅｔｈｏｄｆｏｒｅｓｔｉｍａｔｉｎｇｔｈｅａｎｔｉｏｘｉｄａｎｔａｃｔｉｖｉｔｙ (ＡＡ)ｏｆｆｌａｖｏｎｏｉｄｓｈａｓｂｅｅｎｄｅｖｅｌｏｐｅｄ .Ｔｈｅｐｒｏｐｏｓｅｄｍｅｔｈｏｄｉｓｂａｓｅｄｏｎａｍｅａｓｕｒｅｍｅｎｔｏｆｔｈｅｈａｌｆｗａｖｅｐｏｔｅｎｔｉａｌ(Ｅ1/2 )ｏｆｔｈｅｆｉｒｓｔｏｘｉｄａｔｉｏｎｗａｖｅｏｆｆｌａｖｏｎｏｉｄｓｂｙｕｓｉｎｇｆｌｏｗｔｈｒｏｕｇｈｃｏｌｕｍｎｅｌｅｃｔｒｏｌｙｓｉｓ.Ａｔｔｈｅｓａｍｅｔｉｍｅ ,ｔｈｅｌｉｐｉｄｐｅｒｏｘｉｄａｔｉｏｎ (ＬＰＯ)ｉｎｈｉｂｉｔｉｎｇｅｆｆｅｃｔｓｏｆｔｈｅｓｅｆｌａｖｏｎｏｉｄｓｗｅｒｅｄｅｔｅｒｍｉｎｅｄ .ＡｑｕａｎｔｉｔａｔｉｖｅｓｔｒｕｃｔｕｒｅａｃｔｉｖｉｔｙｒｅｌａｔｉｏｎｓｈｉｐｗａｓｏｂｔａｉｎｅｄｔｏｄｅｓｃｒｉｂｅｔｈｅＡＡｏｆｆｌａｖｏｎｏｉｄｓ:ＩＣ5 0 (μＭ ) =3 0 .3 6+1 51 .50Ｅ1/2 (Ｖ) - 1 2 .63ｌｏｇＰ(ｒ =0 .852 ) ,ｗｈｅｒｅＩＣ5 0 ｒｅｐｒｅｓｅｎｔｓｔｈｅｃｏｎｃｅｎｔ...

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Assessment of Non-Contact Measurement Using a Microwave Sensor to Jugular Venous Pulse Monitoring

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Journal of Biomedical Science and Engineering 2021年第3期14卷 94-102页

作者： Satoshi Suzuki Masaaki Hoshiga Kentaro kotani Takafumi Asao Faculty of Engineering Science Kansai University Osaka Japan Faculty of Medicine Osaka Medical College Osaka Japan

The jugular venous pulse (JVP) waveform provides an insight into right heart function, and its assessment is important in patients with heart failure. However, the conventional pulse-transducer (contact) method for monitoring this waveform is not frequently used because it requires a high degree of skill. The aim of this study was to confirm the effectiveness of a prototype non-contact system that employs microwave radar (24 GHz, 7 mW;non-contact system) for JVP measurement. Experiments were conducted on eight healthy male volunteers (21.88 ± 0.99 years). JVP measurements were compared between the conventional contact method and the proposed non-contact method. Change in JVP waveform was measured in response to an angle of reclining in five steps from the supine position to 75° of elevation. The obtained JVP measurements were similar between the two methods. Because in the non-contact method the faint pulsation of the JVP is not suppressed by the pressure of a sensor placed on the skin, the prototype microwave radar system is particularly suitable for evaluating the JVP waveform.

关键词： Microwave Radar Non-Contact Monitoring Jugular Venous Pressure Right Heart Function

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Effects of Coronavirus Disease 2019 and Frailty on Delirium in the Intensive Care Unit: A Propensity Score Analysis

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Open Journal of Anesthesiology 2023年第2期13卷 23-31页

作者： Takayuki Yamanaka Mitsuru Ida Taich kotani Masahiko Kawaguchi Department of Anesthesiology Nara Medical University Kashihara Nara Japan

Purpose: The association between frailty and delirium has emerged as a research topic. Neurological symptoms have been reported among patients with coronavirus disease 2019 (COVID-19), but its effects on delirium remain unclear. This study aimed to compare the incidence of delirium between patients with COVID-19 and those without COVID-19, and to evaluate the impact of COVID-19 and frailty on delirium. Methods: This retrospective study included patients aged ≥ 20 years who were admitted to our intensive care unit (ICU) between January 2020 and February 2022. An inverse probability of treatment weighting using stabilized inverse propensity scores was adopted to minimize bias. After patient demographics were adjusted, the incidence of delirium, assessed using the Confusion Assessment Method for ICU, was compared between patients with COVID-19 and those without COVID-19. The effects of COVID-19 and the Clinical Frailty Scale score on delirium were analyzed by adjusting some covariates, including the sequential organ failure assessment (SOFA) score, using a generalized estimating equation. Results: Among 260 eligible patients, 226 patients were included. The weighted incidence of delirium was 56.9% and 61.9% in patients with and without COVID-19, respectively (p = 0.67). The generalized estimating equation revealed that the odds ratios (95% confidence interval) for COVID-19, the CFS score, and the SOFA score were 1.49 (0.62 - 3.57), 1.46 (1.11 - 1.91), and 1.22 (1.10 - 1.36), respectively. Conclusion: CFS and SOFA scores on ICU admission may be associated with delirium, with no significant difference between patients with COVID-19 and those without COVID-19.

关键词： COVID-19 Delirium Frailty Intensive Care Unit SARS-CoV-2

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Relationship of Electrochemical Oxidation of Catechins on Their Antioxidant Activity in Microsomal Lipid Peroxidation

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中国实验方剂学杂志 2002年第S1期8卷 -页

作者： Akira kotani Kensuke Arai Fumiyo Kusu

Ｃａｔｅｃｈｉｎｓ (Ｆｉｇ .1 ) ,ｔｈｅｍａｉｎｃｏｎｓｔｉｔｕｅｎｔｓｉｎｇｒｅｅｎｔｅａ ,ｈａｖｅａｔｔｒａｃｔｅｄｌａｓｔｉｎｇｉｎｔｅｒｅｓｔｂｅｃａｕｓｅｏｆｔｈｅｉｒｗｉｄｅｂｉｏｌｏｇｉｃａｌｅｆｆｅｃ...

Ｃａｔｅｃｈｉｎｓ (Ｆｉｇ .1 ) ,ｔｈｅｍａｉｎｃｏｎｓｔｉｔｕｅｎｔｓｉｎｇｒｅｅｎｔｅａ ,ｈａｖｅａｔｔｒａｃｔｅｄｌａｓｔｉｎｇｉｎｔｅｒｅｓｔｂｅｃａｕｓｅｏｆｔｈｅｉｒｗｉｄｅｂｉｏｌｏｇｉｃａｌｅｆｆｅｃｔｓ.Ｒｅｃｅｎｔｌｙ ,ｔｈｅａｎｔｉｏｘｉｄａｎｔａｃｔｉｖｉｔｙ (ＡＡ)ｏｆｃａｔｅｃｈｉｎｓｈａｓｂｅｅｎｗｉｄｅｌｙｒｅｐｏｒｔｅｄ .Ｃａｔｅｃｈｉｎｓｅｆｆｅｃｔｉｖｅｌｙｓｕｐｐｒｅｓｓｅｄｌｉｐｉｄｐｅｒｏｘｉｄａｔｉｏｎ (ＬＰＯ)ｉｎｂｉｏｌｏｇｉｃａｌｔｉｓｓｕｅｓａｎｄｓｕｂｃｅｌｌｕｌａｒｆｒａｃｔｉｏｎｓｓｕｃｈａｓｍｉｔｏｃｈｏｎｄｒｉａ ,ｍｉｃｒｏｓｏｍｅｓ ,ｌｉｐｏｓｏｍｅｓ ,ａｎｄｌｏｗｄｅｎｓｉｔｙｌｉｐｏｐｒｏｔｅｉｎｓ(ＬＤＬ) .[1～ 5 ] Ｏｎｔｈｅｏｔｈｅｒｈａｎｄ ,ｔｈｅｙｅｘｈｉｂｉｔｅｄｓｃａｖｅｎｇｉｎｇａｃｔｉｖｉｔｙｏｎｆｒｅｅｒａｄｉｃａｌｓ ,ｓｕｃｈａｓ 1 ,1’ ｄｉｐｈｅｎｙｌ 2 ｐｉｃｒｙｌｈｙｄｒａｚｙｌ (ＤＰＰＨ )ｒａｄｉｃａｌ,ｓｕｐｅｒｏｘｉｄｅａｎｉｏｎ ,ｈｙｄｒｏｘｙｌｒａｄ...

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基因治疗中逆转录病毒载体转导及生产的改进方法

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国际免疫学杂志 1994年第4期17卷 225-226页

作者： kotani-H 刘杰王敏

基因治疗中逆转录病毒载体转导及生产的改进方法［英］／ＫｏｔａｎｉＨ…／／ＨｕｍａｎＧｅｎｅＴｈｅｒａｐｙ，－１９９４，５．－１９目前进行基因治疗的人体实验不断增多，为了推进逆转录病毒介导的基因转导的临床应用，需要获得... 详细信息

基因治疗中逆转录病毒载体转导及生产的改进方法［英］／ＫｏｔａｎｉＨ…／／ＨｕｍａｎＧｅｎｅＴｈｅｒａｐｙ，－１９９４，５．－１９目前进行基因治疗的人体实验不断增多，为了推进逆转录病毒介导的基因转导的临床应用，需要获得大量最高效价的载体。作者系统地探讨...

关键词：逆转录病毒载体基因治疗基因疗法转导改进方法

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A BLOCK PARTITIONING VECTOR QUANTIZATION METHOD THROUGH POST-PROCESSING TO ACHIEVE HIGHER PSNR

A BLOCK PARTITIONING VECTOR QUANTIZATION METHOD THROUGH POST...

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2002年第6届信号处理国际会议

作者： Koji kotani Tadahiro Ohmi Department of electronic engineering graduate school of engineering Tohoku University SendaiJapan New industry creation hatchery center Tohoku University SendaiJapan AZa-aoba 05AramakiAoba-kuSendai980-8579Japan

＜正＞ In conventional vector quantization（VQ） method, the reachable best PSNR is implemented by full search or its equivalent method when codebook is fixed. To achieve an even higher PSNR by fixed codebook, a post-processing VQ method is proposed in this paper. This method firstly checks how well the VQ matching is for a whole image and locates some bad matching image blocks definitely. Then it partitions a bad matching image block into two partial blocks further by a certain pattern and encodes them once again using the same fixed codebook but two different codes partially. It makes total distortion for current bad matching image block smaller. At the receiving end, current bad matching image block is synthesized by two codes partially according to adopted partitioning pattern so as to realize a better *** 10 gray-level standard images of size 512x512 with different detail, 0.3 dB-1.2 dB PSNR improvement can be reached individually by just partitioning 5% worst matching image blocks at the cost of less than 1 bit degradation of equivalent code length. Moreover this improvement is basically for edge portion of an image. Therefore, subject assessment can be made much better at the same time.

关键词： Vector quantization Block partitioning Post-processing Image quality.

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