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Acta Biochimica et Biophysica Sinica 2007年第1期39卷 1-7页

作者： Masataka NARUKAWA Naoto SUZUKI Tadahiro TAKAYAMA yasuhiko yamashita Kichibee OTSUKA Koichi ITO Department of Periodontology Nihon University School of DentistryTokyo101-8310Japan Department of Biochemistry Nihon University School of DentustryTokyo 101-8310Japan Division of Functional Morphology Dental Research CenterNihon University School of DentistryTokyo 101-8310Japan Department of Biochemistry Nihon University School of DentistryTokyo101-8310Japan Division of Functional Morphology Dental Research CenterNihon University School of DentistryTokyo101-8310Japan Division of Advanced Dental Treatment Dental Research CenterNihon University School of DentistryTokyo101-8310Japan

Our purpose was to determine how enamel matrix derivative (EMD) affects the expression ofosteogenesis- and chondrogenesis-related transcription factors in undifferentiated mesenchymal cells.C3H10T1/2 cell line,a typical pluripotential mesenchymal cell line,was cultured with or without EMD forup to 7 *** of mRNAs encoding osteogenesis-and chondrogenesis-related transcription factors(Runx2, Osterix,AJ18,Dlx5,Msx2,Sox5,Sox9 and Zfp60) was measured using real-time polymerasechain ***2 and Sox9 protein expression and the presence of bone morphogenetic protein (BMP)-6-like molecules in EMD were determined by Western *** substantially increased mRNA levels ofosteogenesis-and chondrogenesis-related transcription *** also induced Runx2 and Sox9 *** blotting analysis of EMD using anti-BMP-6 antibody revealed immunoreactive bandscorresponding to about 14 kDa and 60 *** results suggest that EMD stimulates osteogenesis- andchondrogenesis-related transcription factors,and these activities may be mediated,at least in part,by BMP-6in EMD.

关键词： enamel matrix derivative osteogenesis chondrogenesis

In-silico clearing approach for deep refractive index tomography by partial reconstruction and wave-backpropagation

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Light(Science & Applications) 2023年第5期12卷 877-893页

作者： Osamu yasuhiko Kozo Takeuchi Central Research Laboratory Hamamatsu Photonics K.K5000 HirakuchiHamakita-kuHamamatsu 434-8601 ShizuokaJapan

Refractive index(RI)is considered to be a fundamental physical and biophysical parameter in biological imaging,as it governs light-matter interactions and light propagation while reflecting cellular *** tomography enables volumetric visualization of RI distribution,allowing biologically relevant analysis of a ***,multiple scattering(MS)and sample-induced aberration(SIA)caused by the inhomogeneity in RI distribution of a thick sample make its visualization *** paper proposes a deep RI tomographic approach to overcome MS and SIA and allow the enhanced reconstruction of thick samples compared to that enabled by conventional linear-model-based RI *** proposed approach consists of partial RI reconstruction using multiple holograms acquired with angular diversity and their backpropagation using the reconstructed partial RI map,which unambiguously reconstructs the next partial *** this operation efficiently reconstructs the entire RI tomogram while suppressing MS and *** visualized a multicellular spheroid of diameter 140μm within minutes of reconstruction,thereby demonstrating the enhanced deep visualization capability and computational efficiency of the proposed method compared to those of conventional RI ***,we quantified the high-RI structures and morphological changes inside multicellular spheroids,indicating that the proposed method can retrieve biologically relevant information from the RI *** from the excellent biological interpretability of RI distributions,the label-free deep visualization capability of the proposed method facilitates a noninvasive understanding of the architecture and time-course morphological changes of thick multicellular specimens.

关键词： properties refractive overcome

SYNTHESIS OF CATALYSIS BY THE FUNCTIONALIZATION OF SILICA AND ITS APPLICATIONS

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Chinese Journal of Polymer Science 1999年第1期17卷 1-12页

作者： yasuhiko Kurusu Department of Chemistry Sophia University 7-1 Kioicho Chiyoda-ku Tokyo Japan 102

Hybrid organic-inorganic silica materials containing organic functional groups have been preparedby the reaction of activated silica with a silane coupling reagent such as N-(2-aminoethyl)3-aminopropyltrimethoxysilane. The hybrid silica was further modified by organic compounds having abifunctional group. These modified hybrid silicas were used as catalysts for various nucleophilic *** also, these were complexed with metallic ions for use as catalysts for oxygen oxidation of hydrocarbons.

关键词： Organic-inorganic hybrid polymer Functionalized silica Dioxygen oxidation of hydrocarbon Reaction with functionalized silica

Living-donor liver transplantation for patients with hepatocellular carcinoma in Japan: Current situations and challenge

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Hepatobiliary & Pancreatic Diseases International 2020年第1期19卷 1-2页

作者： yasuhiko Sugawara Department of Transplantation/Pediatric Surgery Postgraduate School of Life Science Kumamoto University

Liver transplantation has now been a standard therapy for patients with hepatocellular carcinoma(HCC)in the early stage[1].Liver transplantation is an ideal treatment for HCC which can treat both the tumors and the un... 详细信息

关键词： patients hepatocellular Liver

Pilot Study to Examine Radial Variation in Annual Ring Width, Density and Shrinkage

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Chinese Forestry Science and Technology 2003年第4期2卷 25-30页

作者： URAKAMI Hiroyuki HIRAKAWA yasuhiko yamashita Kana Research Institute of Wood Industry Chinese Academy of Forestry Beijing 100091 ChinaForestry and Forest Products Research Institute JapanForestry and Forest Products Research Institute Japan

The annual ring width, density and shrinkage variation from pith to bark in Chinese fir (Cunninghamia lanceolata) and Boka sugi (Cryptomeria japonicd) were studied and compared. The results show that the ring width decreased sharply from pith to bark for Chinese fir. However, the ring width variation pattern for Boka sugi followed a different way, i.e., the ring width decreased to the fifth ring, increased to the tenth ring, decreased again to the fifteenth, and then increased to the twentieth, where it...

关键词： plantation wood annual ring width density variation shrinkage characteristics Chinese fir Boka sugi

Living donor liver transplantation to patients with hepatitis C virus cirrhosis

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World Journal of Gastroenterology 2006年第28期12卷 4461-4465页

作者： yasuhiko Sugawara Masatoshi Makuuchi Artificial Organ and Transplantation Division Department of SurgeryGraduate School of MedicineUniversity of Tokyo7-3-1 HongoBunkyokuTokyo 113-8655Japan

Living donor liver transplantation （LDLT） is an alternative therapeutic option for patients with end-stage hepatitis C virus （HCV） cirrhosis because of the cadaveric organ shortage. HCV infection is now a leading indication for LDLT among adults worldwide, and there is a worse prognosis with HCV recurrence. The antivirus strategy after transplantation, however, is currently under debate. Recent updates on the clinical and therapeutic aspects of living donor liver transplantation for HCV are discussed in the present review.

关键词： Hepatitis C virus Living donor liver transplantation Interferon Rivabirin

FUZZY DECISION MAKING FOR SELECTION OF INFORMATION SYSTEM DEVELOPMENT APPROACH

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中国有色金属学会会刊：英文版 1998年第1期8卷 173-177页

作者： Chen, Xiaohong Liu, Mai Takahara, yasuhiko Central South Univ of Technology Changsha China

ＦＵＺＺＹＤＥＣＩＳＩＯＮＭＡＫＩＮＧＦＯＲＳＥＬＥＣＴＩＯＮＯＦＩＮＦＯＲＭＡＴＩＯＮＳＹＳＴＥＭＤＥＶＥＬＯＰＭＥＮＴＡＰＰＲＯＡＣＨ①ＣｈｅｎＸｉａｏｈｏｎｇａｎｄＬｉｕＭａｉＣｏｌｅｇｅｏｆＢｕｓｉｎｅｓａｎ... 详细信息

ＦＵＺＺＹＤＥＣＩＳＩＯＮＭＡＫＩＮＧＦＯＲＳＥＬＥＣＴＩＯＮＯＦＩＮＦＯＲＭＡＴＩＯＮＳＹＳＴＥＭＤＥＶＥＬＯＰＭＥＮＴＡＰＰＲＯＡＣＨ①ＣｈｅｎＸｉａｏｈｏｎｇａｎｄＬｉｕＭａｉＣｏｌｅｇｅｏｆＢｕｓｉｎｅｓａｎｄＭａｎａｇｅｍｅｎｔ，Ｃｅｎｔｒ...

关键词： ISDA fuzzy decision making fuzzy synthetic descrimination model

Effects of Diffuser Vane Geometry on Interaction Noise Generated from a Centrifugal Compressor

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Journal of Thermal Science 2005年第4期14卷 321-328页

作者： Yutaka OHTA Naho TAKEHARA yasuhiko OKUTSU Eisuke OUTA Department of Mechanical Engineering Waseda University 3-4-1 Okubo ShinjukuTokyo 169-8555Japan

The characteristics of interaction tone noise radiated from a centrifugal compressor with a vaned diffuser are discussed by experiments, including visualization techniques using the oil-film method. Research attention is paid to the leading edge geometries of the diffuser vanes that are deeply related to the generation mechanism of the interaction tone noise. The compressor-radiated noise can be reduced by several decibels by setting some clearances in both the hub and shroud surfaces of the diffuser wall along with some decline in the pressure-rise coefficient. Since the decline turned out to be caused by the flow impingement and also by the secondary flow within the diffuser passages, several new types of diffuser vane geometries which do not detract from both the performance and noise level are developed and utilized for the experiments. The presented diffuser vane geometries will offer a few basic guidelines for the diffuser vane design.

关键词： centrifugal compressor vaned diffuser interaction noise noise reduction.

Dynamics and geometry of developing planar jets based on the invariants of the velocity gradient tensor

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Journal of Hydrodynamics 2015年第6期27卷 894-906页

作者：吴楠楠 SAKAI yasuhiko NAGATA Kouji ITO Yasumasa School of Electric Power Engineering China University of Mining and Technology Department of Mechanical Science and Engineering Nagoya University

Based on the direct numerical simulation （DNS）, the developing planar jets under different initial conditions, e.g., the con- ditions of the exit Reynolds number and the exit mean velocity profile, are investigated. We mainly focus on the characteristics of the invariants of the velocity gradient tensor, which provides insights into the evolution of the dynamics and the geometry of the planar jets along with the flow transition. The results show that the initial flow near the jet exit is strongly predominated by the dissipation over the enstrophy, the flow transition is accompanied by a severe rotation and straining of the flow elements, where the vortex structure evolves faster than the fluid element deformation, in the fully-developed state, the irrotational dissipation is dominant and the most probable geometry of the fluid elements should remain between the biaxial stretching and the axisymmetric stretching. In addition, with a small exit Re and a parabolic profile for the exit mean streamwise velocity, the decay of the mean flow field and the magnitude of the turbulent variables will be strengthened in the process of the flow transition, however, a large exit Re will promote the flow transition to the fully-developed state. The cross-impact between the exit Re and the exit mean velocity profile is also observed in the present study.

关键词： planar jet direct numerical simulation (DNS) velocity gradient tensor flow transition joint probability density function(joint pdf)

Study and evaluation of a plant form modeling system based on the Lindenmayer system

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International Journal of Modeling, Simulation, and Scientific Computing 2018年第3期9卷 107-114页

作者： Taiyo Maeda yasuhiko Manabe Shigeo Kawata Department of System Engineering Graduate School of Engineering Saitama Institute of Technology 1690 Fusaiji FukayaSaitama 369-0293Japan Department of Electrical and Electronics Engineering National Institute of Technology Numazu CollegeJapan Department of Electrical and Electronic Engineering Graduate School of Engineering Utsunomiya UniversityJapan

In order to evaluate and recognize plant growth automatically based on photos of plants in plant science and engineering,we propose a diagnostic system for plant growth in which simulated plant growth is used as a reference for real growing *** our diagnostic system,we employ the Lindenmayer system[Lecture Notes in Computer Science,15,53–68,1974]to model healthy growing *** the Lindenmayer system plant growth is expressed by string expressions designed as a numerical model for the *** proposal system provides users the string expressions by using image *** users compare with two strings such as DNA sequence genetic code,users obtain developmental change of plat *** results show that our automatic plant diagnostic system is effective in checking actual healthy plant growth,and suggest that the diagnostic system should be useful in large-scale plant factories.

关键词： Plant growth Lindenmayer system string expression for plant modeling