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Daily Lifestyle Habits as Risk Factors for Plaque-Induced Gingivitis and Periodontitis Severity and Grading among Samples of Dental Students at King Khalid University

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International Journal of Clinical Medicine 2023年第2期14卷 65-78页

作者： Mohammed M. A. Abdullah Al-Abdaly Amer Hassan Alasmari Feras Ali Alsaeed Ali Abdullah Ali Alqhtani Fahad Hassan Alhifthi yasir saad jaadan Periodontics and Community Dental Sciences College of Dentistry King Khalid University Abha Saudi Arabia College of Dentistry King Khalid University Abha Saudi Arabia

Objective: To assess daily lifestyle habits as risk factors for plaque-induced gingivitis and periodontitis severity and grading among samples of dental students at King Khalid University. Material and Methods: This study included 150 male participants. They were divided according to the levels into three equal groups: levels 5, 6, and 7 (group I), levels 8, 9, 10 (group II) and levels 11, 12, and interns (group III). This study consisted of questions related to age, gender, educational level, father’s education, mother’s education, home ownership, brushing teeth more than or twice a day, in addition to daily lifestyle habits that were daily smoking, daily use of sugary drinks, and daily use of sugary foods. Some clinical parameters of plaque-induced gingivitis and periodontitis and the percentage of radiographic bone loss were recorded. All data were collected and analyzed using Tukey’s test and Chi-square test. A P-value of less than 0.5 (p Results: One hundred fifty male dental students of different levels in the college of dentistry at King Khalid University participated in the study in three groups (I, II, and III). The mean age of group III is more than that of group II and group I, with highly statistically significant differences (p 30%) were more among the participants in group I than the participants in groups III and II. There was an increase in the percentage of affected participants with stages III and IV of clinical attachment loss (CAL), periodontal pocket depth (PPD), radiographic bone loss (%RBL), tooth mobility, as well as glycated hemoglobin (HbA1c) test values (>7%), and the number of cigarettes smoked per day (>10 cigs) in group III more than in group II and I. Conclusion: We conclude that the severity and grading of plaque-induced gingivitis were higher among the participants in group I, while the severity and grading of periodontitis were higher among the participants in group III due to the different impact of their daily lifestyle habits.

关键词： Daily Lifestyle Dental Students King Khalid University Periodontitis Plaque-Induced Gingivitis

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Daily Lifestyle Habits as Risk Factors for Plaque-Induced Gingivitis and Periodontitis Severity and Grading among Samples of Dental Students at King Khalid University

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International Journal of Clinical Medicine（临床医学国际期刊） 2023年第2期

作者： Mohammed M. A. Abdullah Al-Abdaly Amer Hassan Alasmari Feras Ali Alsaeed Ali Abdullah Ali Alqhtani Fahad Hassan Alhifthi yasir saad jaadan

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Maternal TMPRSS6 Gene Polymorphism rs855791SNP in Women with Preeclampsia

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Journal of Biosciences and Medicines 2023年第1期11卷 70-81页

作者： yasir I. B. Ahmed Hind S. Yagoub Mohamed A. Hassan Department of Haematology and Immunohematology Faculty of Medical Laboratory Sciences Omdurman Islamic University Omdurman Sudan Department of Medical Laboratory Technology College of Applied Medical Sciences Taibah University Medina Saudi Arabia Africa City of Technology Khartoum Sudan

Introduction: Preeclampsia can lead to several maternal and perinatal adverse effects. There are few published data on the association between transmembrane serine protease 6 (TMPRSS6) gene polymorphism and preeclampsia. Objective: To assess the association between TMPRSS6 gene polymorphism rs855791SNP in women with preeclampsia compared with healthy pregnant women. Method: A case-control study (60 women in each arm) was conducted at saad Abuaela Maternity Hospital in Khartoum, Sudan. Sociodemographic and clinical data were gathered through a questionnaire. The participant was genotype for TMPRSS6 gene rs855791SNP using Polymerase Chain Reaction and Restriction Fragment Length Polymorphism (PCR-RFLP). The results were confirmed by DNA sequencing. Result: There was no significant difference in the median of age, parity, and body mass index. The distribution of the genotypes and alleles of TMPRSS6 rs855791 was consistent with the HWE. The overall TMPRSS6 rs855791 polymorphism was not significantly associated with preeclampsia. However, the proportion of heterozygotes (TC) was considerably higher in the women with preeclampsia (46.7%) than in the control group (23.3%) (p = 0.001;OR = 2.71;95% CI = 1.21 - 6.07). The proportion of homozygotes (TT) and T alleles was not significantly different between women with preeclampsia and the control group. Conclusion: The overall TMPRSS6 rs855791 polymorphism was not significantly associated with preeclampsia and healthy control.

关键词： Preeclampsia TMPRSS6 Gene Polymorphism rs855791SNP

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