检索结果-南通市图书馆

The role of acetazolamide in critical care and emergency medicine

Journal of Geriatric Cardiology 2024年第11期21卷 1085-1095页

作者： Jacopo Davide Giamello Gabriele Savioli yaroslava longhitano Fiorenza Ferrari Salvatore D’Agnano Ciro Esposito Manfredi Tesauro Christian Zanza Department of Emergency Medicine Azienda Ospedaliera S.Croce e CarleCuneoItaly Emergency Medicine and Surgery IRCCS Fondazione Policlinico San MatteoPaviaItaly Department of Anesthesiology and Perioperative Medicine University of PittsburghPittsburghPA 15260USA Department of Emergency Medicine-Emergency Medicine Residency Program Humanitas University-Research Hospital20089 RozzanoItaly International Renal Research Institute of Vicenza(IRRIV) Department of NephrologyDialysis and TransplantationSan Bortolo HospitalAzienda ULSS Berica VicenzaItaly Department of Anaesthesia Critical Care and EmergencyFoundation IRCCS Ca'Granda Ospedale Maggiore PoliclinicoMilanItaly Unit of Nephrology and Dialysis ICS MaugeriUniversity of PaviaPaviaItaly Department of Systems Medicine University of Rome"Tor Vergata"RomeItaly Geriatric Medicine Residency Program University of Rome"Tor Vergata"RomeItaly

Acetazolamide is the commonly prescribed oral and intravenous carbonic anhydrase inhibitor;over the years,its use in clinical practice has decreased in favor of more recent ***,it is a rather handy drug,which can be useful in several clinical settings when managing critically ill *** objective of this review is the evaluation of the most recent evidence on the use of acetazolamide in emergency medicine and critical care ***,the safety profile of this drug has been *** is a narrative review on the use of acetazolamide in the main contexts in which this drug can be useful in emergency situations for patients with potential critical *** the timeline 1999–2024,a search was conducted on the main scientific platforms;resources of greatest relevance for the use of acetazolamide in critical care and emergency medicine were *** most common emergency situations in which a critically ill patient could benefit from acetazolamide therapy are acute heart failure,acute mountain sickness,post hypercapnic metabolic alkalosis,idiopathic intracranial hypertension and acute angle-closure *** a few cases,however,randomized controlled clinical trials have been *** are also other less solid indications based mostly on experience or retrospective *** seems to be an overall safe drug;serious side effects are rare and can be avoided by carefully selecting the patients to be *** represents a precious resource for emergency physicians and intensivists;critical patients with different conditions can in fact benefit from it;furthermore,acetazolamide is a safe drug if administered to correctly selected patients.

关键词： critical prescribed furthermore

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of functional foods, nutraceuticals, and herbal products on pancreas

引用

Chinese Medical Journal 2023年第5期136卷 619-620页

作者： Angela Saviano Christian Zanza yaroslava longhitano Enrico Celestino Nista Francesco Franceschi Veronica Ojetti Department of Emergency Medicine Fondazione Policlinico Universitario Agostino GemelliIRCCSRomeItaly Foundation“Ospedale Alba-Bra”and Department of Anesthesia Critical Care and Emergency MedicineMichele and Pietro Ferrero HospitalVerdunoItaly Department of Anesthesiology and Perioperative Medicine University of PittsburghPittsburghPAUSA Department of Gastroenterology Fondazione Policlinico Universitario Agostino GemelliIRCCSRomeItaly.

To the Editor:Today functional foods,nutraceuticals,and herbal products are becoming a part of human daily *** patient’s interest and demand for them are ***,healthcare systems and people have shown an increased desire to prevent some diseases and to improve their *** data about the properties and side effects of these products on the pancreas are still lacking,and more studies are required to provide a definitive opinion on their clinical benefits and *** industry of functional foods,nutraceuticals,and herbal products is gaining popularity.

关键词： herbal functional becoming

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Oxidation of diesel soot on binary oxide Cu Cr(Co)-based monoliths

引用

Journal of Environmental Sciences 2015年第2期27卷 171-177页

作者： Sergiy O.Soloviev Andriy Y.Kapran yaroslava P.Kurylets L.V.Pisarzhevskii Institute of Physical Chemistry National Academy of Sciences of Ukraine

Binary oxide systems（Cu Cr2O4, Cu Co2O4）, deposited onto cordierite monoliths of honeycomb structure with a second support（finely dispersed Al2O3）, were prepared as filters for catalytic combustion of diesel soot using internal combustion engine’s gas exhausts（O2, NOx, H2 O, CO2） and O3 as oxidizing agents. It is shown that the second support increases soot capacity of aforementioned filters, and causes dispersion of the particles of spinel phases as active components enhancing thereby catalyst activity and selectivity of soot combustion to CO2. Oxidants used can be arranged with reference to decreasing their activity in a following series： O3 NO2〉 H2 O 〉 NO 〉 O2〉 CO2. Ozone proved to be the most efficient oxidizing agent： the diesel soot combustion by O3 occurs intensively（in the presence of copper chromite based catalyst） even at closing to ambient *** obtained give a basis for the conclusion that using a catalytic coating on soot filters in the form of aforementioned binary oxide systems and ozone as the initiator of the oxidation processes is a promising approach in solving the problem of comprehensive purification of automotive exhaust gases at relatively low temperatures, known as the ＂cold start＂ problem.

关键词： Catalyzed diesel particulate filters Cu Cr2O4 Cu Co2O4catalytic coatings Cordierite monoliths Second support Oxidizing agents Ozone

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

里姆斯基—科萨科夫歌剧《雪姑娘》中女中音角色“列尔”的分析

里姆斯基—科萨科夫歌剧《雪姑娘》中女中音角色“列尔”的分析

引用

作者： yaroslava Bozhko（雅拉）上海音乐学院

学位级别：硕士

作为来自俄罗斯的声歌系硕士,笔者观察到中国听众对俄罗斯歌剧音乐的浓厚兴趣。但专注于俄罗斯声乐研究的学术文献数量有限,这凸显了该领域尚未开发的潜力。本研究第一章探讨里姆斯基-科萨科夫歌剧《雪姑娘》的总体背景,探讨其创作背后... 详细信息

作为来自俄罗斯的声歌系硕士,笔者观察到中国听众对俄罗斯歌剧音乐的浓厚兴趣。但专注于俄罗斯声乐研究的学术文献数量有限,这凸显了该领域尚未开发的潜力。本研究第一章探讨里姆斯基-科萨科夫歌剧《雪姑娘》的总体背景,探讨其创作背后的文化、历史和个人动机,从历史、文化和哲学的角度提供了研究视角。此外,本研究还考察了歌剧的情节,重点关注其音乐属性,并对人物、他们的行为以及叙述叙事的更广泛的文化背景进行了简要分析。第二章着重对女中音角色“列尔”进行分析。本章从探索他的背景故事以及与其他角色的互动开始,深入探讨该角色在歌剧中的角色文化意义。此外,第二节更深入地探讨了“列尔”与斯拉夫文化的联系。接着第三节通过对列尔的三首歌曲进行音乐分析,丰富了读者对这个多面角色的理解。第三章通过比较研究进行更深层次的思考。第一节提供了《雪姑娘》中其他女中音角色的一般信息。第二节对两位歌手在塑造“列尔”这一角色时的演唱和表演方式进行了详细的比较。本章最后为表演者提供了富有洞察力的结论和中肯的建议

关键词：里姆斯基-科萨科夫雪姑娘列尔俄罗斯歌剧角色分析女中音

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Nanoscale architecture of ceria-based model catalysts: Pt-Co nanostructures on well-ordered CeO_(2)(111) thin films

引用

Chinese Journal of Catalysis 2020年第6期41卷 985-997页

作者： yaroslava Lykhach TomásSkála Armin Neitzel Nataliya Tsud Klára Beranová Kevin CPrince Vladimír Matolín Jorg Libuda Interface Research and Catalysis Erlangen Catalysis Resource CenterFriedrich-Alexander-Universit?t Erlangen-NürnbergEgerlandstrasse 391058 ErlangenGermany Charles University Faculty of Mathematics and PhysicsDepartment of Surface and Plasma ScienceV Hole?ovi?kách 218000 PragueCzech Republic Elettra-Sincrotrone Trieste SCpA Strada Statale 14km 163.534149 Basovizza-TriesteItaly

We have prepared and characterized atomically well-defined model systems for ceria-supported Pt-Co core-shell catalysts. Pt@Co and Co@Pt core-shell nanostructures were grown on well-ordered CeO2(111) films on Cu(111) by physical vapour deposition of Pt and Co metals in ultrahigh vacuum and investigated by means of synchrotron radiation photoelectron spectroscopy and resonant photoemission spectroscopy. The deposition of Co onto CeO2(111) yields CoCeO2(111) solid solution at low Co coverage(0.5 ML), followed by the growth of metallic Co nanoparticles at higher Co coverages. Both Pt@Co and Co@Pt model structures are stable against sintering in the temperature range between 300 and 500 K. After annealing at 500 K, the Pt@Co nanostructure contains nearly pure Co-shell while the Pt-shell in the Co@Pt is partially covered by metallic Co. Above 550 K, the re-ordering in the near surface regions yields a subsurface Pt-Co alloy and Pt-rich shells in both Pt@Co and Co@Pt nanostructures. In the case of Co@Pt nanoparticles, the chemical ordering in the near surface region depends on the initial thickness of the deposited Pt-shell. Annealing of the Co@Pt nanostructures in the presence of O2 triggers the decomposition of Pt-Co alloy along with the oxidation of Co, regardless of the thickness of the initial Pt-shell. Progressive oxidation of Co coupled with adsorbate-induced Co segregation leads to the formation of thick CoO layers on the surfaces of the supported Co@Pt nanostructures. This process is accompanied by the disintegration of the CeO2(111) film and encapsulation of oxidized Co@Pt nanostructures by CeO2 upon annealing in O2 above 550 K. Notably, during oxidation and reduction cycles with O2 and H2 at different temperatures, the changes in the structure and chemical composition of supported Co@Pt nanostructures were driven mainly by oxidation while reduction treatments had little effect regardless of the initial thickness of the Pt-shell.

关键词： Core-shell nanoparticles Model catalyst Pt-Co Cerium oxide Chemical ordering Synchrotron radiation photoelectron spectroscopy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cellulose synthase ‘class specific regions’ are intrinsically disordered and functionally undifferentiated

引用

Journal of Integrative Plant Biology 2018年第6期60卷 481-497页

作者： Tess R.Scavuzzo-Duggan Arielle M.Chaves Abhishek Singh Latsavongsakda Sethaphong Erin Slabaugh yaroslava G.Yingling Candace H.Haigler Alison W.Roberts Department of Biological Sciences University of Rhode Island120 Flagg RoadKingstonRI 02881USA Department of Materials Science and Engineering North Carolina State UniversityRaleighNC 27695USA Department of Crop and Soil Sciences and Department of Plant and Microbial Biology North Carolina State UniversityRaleighNC 27695USA

Cellulose synthases （CESAs） are glycosyltransferases that catalyze formation of cellulose microfibrils in plant cell walls. Seed plant CESA isoforms cluster in six phylogenetic clades, whose non-interchangeable members play distinct roles within cellulose synthesis complexes （CSCs）. A ＇class specific region＇（CSR）, with higher sequence similarity within versus between functional CESA classes, has been suggested to contribute to specific activities or interactions of different isoforms. We investigated CESA isoform specificity in the moss, Physcomitrella patens （Hedw.） B. S. G. to gain evolutionary insights into CESA structure/function relationships. Like seed plants, P. patens has oligomeric rosette-type CSCs, but the PpCESAs diverged independently and form a separate CESA clade. We showed that P. patens has two functionally distinct CESAs classes, based on the ability to complement the gametophore-negative phenotype of a ppcesa5 knockout line. Thus, non-interchangeable CESA classes evolved separately in mosses and seed plants. However, testing of chimeric moss CESA genes for complementation demonstrated that functional classspecificity is not determined by the CSR. Sequence analysis and computational modeling showed that the CSR is intrinsically disordered and contains predicted molecular recognition features, consistent with a possible role in CESA oligomerization and explaining the evolution of class-specific sequences without selection for class-specific function.

关键词： Uwe Sonnewald Friedrich-Alexander University Germany

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

点突变对胶原纤维结构和机械性能的影响：分子动力学研究

引用

北京皮革（中外鞋讯）（下） 2013年第5期 91-95页

作者： Ashley E. Marlowe Abhishek Singh yaroslava G. Yingling 何青(编译) Department of Materials Science and Engineering North Carolina Stare University 911 Partners Way Raleigh NO 27695 USA 四川大学制革清洁技术国家工程实验室

现代人对胶原机械性能和结构的理解程度，对于生物医学材料以及纳米技术的应用至关重要。而且，点突变与许多胶原类疾病有关，其中包括成骨不全症（OI）。我们进行一系列传统研究以及能够操纵原子的分子动力学模拟，以便检测点突变对于... 详细信息

现代人对胶原机械性能和结构的理解程度，对于生物医学材料以及纳米技术的应用至关重要。而且，点突变与许多胶原类疾病有关，其中包括成骨不全症（OI）。我们进行一系列传统研究以及能够操纵原子的分子动力学模拟，以便检测点突变对于胶原纤维结构和机械性能的影响，包括甘氨酸到丙氨酸、天冬氨酸、半胱氨酸和丝氨酸的突变以及羟脯氨酸到精氨酸、天冬酰胺、谷酰胺和赖氨酸的突变。研究发现，所有点突变均能分散胶原纤维的结构，并降低其强度，从而影响纤维的层堆积。相对于羟脯氨酸突变（wT〉Arg〉Glu〉Asn〉Lys），甘氨酸突变（wT〉Ala〉ser〉cys〉Asp）对纤维的机械强度的影响更为有害。甘氨酸突变的临床表现与通过分子模拟预言纤维可拉伸强度降低的趋势相一致。大体上，胶原纤维机械性能的降低能够预言点突变的临床表现。

关键词：胶原纤维分子动力学模拟点突变成骨不全症机械性能

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：