检索结果-南通市图书馆

Oral administration of a non-absorbable plant cellexpressed recombinant anti-TNF fusion protein induces immunomodulatory effects and alleviates nonalcoholic steatohepatitis

引用

World Journal of Gastroenterology 2016年第39期22卷 8760-8769页

作者： yaron Ilan Ami Ben Ya'acov Yehudit Shabbat Svetlana Gingis-Velitski einat Almon Yoseph Shaaltiel Gastro-enterology and Liver Units Department of MedicineHadassah Hebrew University Medical CenterJerusalem IL 91120Isreal Protalix Biotherapeutics Carmel 20100Israel

AIM To evaluate the immunomodulatory effect of oral administration of PRX-106 in the high-fat diet *** For 22 wk, C57BL/6 HFD-fed mice received daily oral treatments with BY-2 cells expressing recombinant antitumor necrosis factor alpha fusion protein(PRX-106). Mice were followed for serum liver enzyme and triglyceride levels, liver histology and intrahepatic and systemic *** The orally administered non-absorbable PRX-106 w a s b i o l o g i c a l l y a c t i v e. A l t e r e d d i s t r i b u t i o n o f CD4+CD25+Fox P3+ between the liver and spleen and an increase in the intrasplenic-to-intrahepatic CD4+CD25+Fox P3+ ratio and a decrease in the intrasplenic-to-intrahepatic CD8+CD25+Fox P3+ ratio were observed. An increase in intrahepatic NKT cells and a decrease in the intrasplenic-to-intrahepatic NKT ratio were noted. Assessment of the CD4-to-CD8 ratios showed sequestration of CD8+ lymphocytes in the liver. These effects were associated with a decrease in serum triglyceride levels, decrease in the aspartate aminotransferase levels, serum glucose levels, and HOMA-IR score. A decrease in hepatic triglycerides content was observed in the high dose-treated *** Orally administered PRX-106 shows biological activity and exerts an immunomodulatory effect, alleviating liver damage. The data suggest that PRX-106 may provide an oral immunotherapy for nonalcoholic steatohepatitis.

关键词： Nonalcoholic steatohepatitis Nonalcoholic fatty liver disease Tumor necrosis alpha enbrel Diabetes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Coupled Ieee 802.11ac and TCP Goodput Improvement Using Aggregation and Reverse Direction

引用

Wireless Sensor Network 2016年第7期8卷 107-136页

作者： Oran Sharon yaron Alpert Department of Computer Science Netanya Academic College Netanya Israel Intel Ra’anana Israel

This paper suggests a new model for the transmission of Transmission Control Protocol (TCP) traffic over Ieee 802.11 using the new features of Ieee 802.11ac. The paper examines the first step in this direction and as such we first consider a single TCP connection, which is typical in a home environment. We show that when the Ieee 802.11ac MAC is aware of QoS TCP traffic, using Reverse Direction improves the TCP Goodput in tens of percentages compared to the traditional contention based channel access. In an error-free channel this improvement is 20% while in an error-prone channel the improvement reaches 60% also using blind retransmission of frames. In our operation modes we also assume the use in Two-Level aggregation scheme, the Automatic Repeat-Request (ARQ) protocol of the Ieee 802.11ac MAC layer, the data rates and the four Access Categories defined in this standard.

关键词： 802.11ac TCP Aggregation Reverse Direction Goodput

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oral Co-administration of Soy-derived extracts with Alcohol or with Sugar-sweetened Beverages exerts Liver and Sugar Protective effects

引用

Journal of Clinical and Translational Hepatology 2017年第3期5卷 208-215页

作者： Tawfik Khoury Devorah Rotnemer-Golinkin Yehudit Shabat Lidya Zolotarovya yaron Ilan Gastroenterology and Liver Units Department of Medicine Hadassah-Hebrew University Medical CenterJerusalem Israel

Background and Aims:Both alcoholic drinks and high sugar-containing soft drinks cause major health problems *** administration of OS and M1 soy-derived extracts has been shown to alleviate liver injury in animal *** aim of the present study was to determine the liver-and sugar-protective effect of OS and M1 soy-derived extracts when added to alcohol and sugar-enriched ***:Mice were treated with alcohol or high sugarcontaining drinks,with and without administration of a combination of OS and M1 soy *** were observed for the effects on liver injury,glucose metabolism,and the immune ***:Co-administration of the soy extracts OS and M1 significantly alleviated the liver injury induced by acute alcohol,as evidenced by decreased liver *** beneficial effects were associated with promotion of subsets of regulatory T lymphocytes and with a trend towards a pro-inflammatory to an anti-inflammatory cytokine ***-administration of OS M1 soy extracts with sugar-sweetened beverages significantly alleviated the increases in serum sugar ***:OS and M1 extracts exert a synergistic hepato-and glucose-protective effect in models of alcohol-induced liver damage and soft drinks-associated increases in serum *** extracts may provide a solution to the two pressing health problems.

关键词： Soy Soda drinks Alcoholic liver disease T regulatory cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A New Aggregation Based Scheduling Method for Rapidly Changing Ieee 802.11ac Wireless Channels

引用

Wireless Sensor Network 2016年第8期8卷 145-165页

作者： Oran Sharon yaron Alpert Department of Computer Science Netanya Academic College Netanya Israel Intel Ra’anana Israel

In this paper we suggest a novel idea to improve the Throughput of a rapidly changing WiFi channel by exploiting the standard aggregation schemes in Ieee 802.11ac networks. The idea is based on blindly transmitting several copies of the first 4 MAC Protocol Data Units (MPDU) in the Transmission Window. This increases the probability that the window moves forward, enabling the transmission of new MPDUs and resulting in increased Throughput. It turns out that transmitting 2 copies of each of the first 4 MPDUs yields the best Throughput gain, in the order of 50% - 60% in PHY rates of 1.3 - 3.5 Gbps and few hundreds of bytes MPDUs. The proposed idea has advantage over Link Adaptation since it reduces the actual PHY rate only for the transmission of few MPDUs while Link Adaptation reduces the PHY rate for all the transmissions.

关键词： 802.11ac Aggregation Scheduling Link Adaptation Reliability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Scheduling Strategies and Throughput Optimization for the Downlink for Ieee 802.11ax and Ieee 802.11ac Based Networks

引用

Wireless Sensor Network 2017年第10期9卷 355-383页

作者： Oran Sharon yaron Alpert Department of Computer Science Netanya Academic College Netanya Israel Intel Ra’anana Israel

The new Ieee 802.11ax standard is aimed to serve many users while enabling every station to transmit a consistent stream of data without interruption. In this paper we evaluate the upper bound on the throughput of a Downlink Ieee 802.11ax channel using the Single User (SU) mode and using the Multi User Multiple-Input-Multiple-Output (MU-MIMO) and Orthogonal Frequency Division Multiple Access (OFDMA) mode. We compare between Ieee 802.11ax and Ieee 802.11ac for the case of 1, 4, 8, 16, 32 and 64 stations in different Modulation/Coding schemes (MCS) and different transmission windows’ sizes, 64 and 256 frames in Ieee 802.11ax. Ieee 802.11ax outperforms Ieee 802.11ac in the SU and MU modes by 52% and 74% in a reliable channel respectively, while in an unreliable channel the improvements are by 59% and 103% respectively. Also, in terms of the access delay, the advantage of Ieee 802.11ax increases as the number of stations increases.

关键词： Ieee 802.11ax Ieee 802.11ac Throughput Single User MU-MIMO OFDMA

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Single User MAC Level Throughput Comparision: Ieee 802.11ax vs. Ieee 802.11ac

引用

Wireless Sensor Network 2017年第5期9卷 166-177页

作者： Oran Sharon yaron Alpert Department of Computer Science Netanya Academic College 1 University Street Netanya Israel Intel Ra’anana Israel

With the ever-increasing range of video and audio applications in portable handheld devices, demand for high throughput in Wi-Fi networks is escalating. In this paper we introduce several novel features defined in next generation WLAN, termed as Ieee 802.11ax standard, and compare between the maximum throughputs received in Ieee 802.11ax and Ieee 802.11ac in a scenario where the AP continuously transmits to one station in the Single User mode. The comparison is done as a function of the modulation/coding schemes in use. In Ieee 802.11ax we consider two levels of frame aggregation. Ieee 802.11ax outperforms Ieee 802.11ac by about 29% and 48% in reliable and unreliable channels respectively.

关键词： Ieee 802.11ax Ieee 802.11ac Throughput Single User Aggregation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Scheduling Strategies and Throughput Optimization for the Uplink for Ieee 802.11ax and Ieee 802.11ac Based Networks

引用

Wireless Sensor Network 2017年第8期9卷 250-273页

作者： Oran Sharon yaron Alpert Department of Computer Science Netanya Academic College 1 University St. Netanya Israel Intel Ra’anana Israel

The new Ieee 802.11 standard, Ieee 802.11ax, has the challenging goal of serving more Uplink (UL) traffic and users as compared with his predecessor Ieee 802.11ac, enabling consistent and reliable streams of data (average throughput) per station. In this paper we explore several new Ieee 802.11ax UL scheduling mechanisms and compare between the maximum throughputs of unidirectional UDP Multi Users (MU) triadic. The evaluation is conducted based on Multiple-Input-Multiple-Output (MIMO) and Orthogonal Frequency Division Multiple Access (OFDMA) transmission multiplexing format in Ieee 802.11ax vs. the CSMA/CA MAC in Ieee 802.11ac in the Single User (SU) and MU modes for 1, 4, 8, 16, 32 and 64 stations scenario in reliable and unreliable channels. The comparison is conducted as a function of the Modulation and Coding Schemes (MCS) in use. In Ieee 802.11ax we consider two new flavors of acknowledgment operation settings, where the maximum acknowledgment windows are 64 or 256 respectively. In SU scenario the throughputs of Ieee 802.11ax are larger than those of Ieee 802.11ac by 64% and 85% in reliable and unreliable channels respectively. In MU-MIMO scenario the throughputs of Ieee 802.11ax are larger than those of Ieee 802.11ac by 263% and 270% in reliable and unreliable channels respectively. Also, as the number of stations increases, the advantage of Ieee 802.11ax in terms of the access delay also increases.

关键词： Ieee 802.11ax Ieee 802.11ac Throughput Single User MU-MIMO OFDMA

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ownership Concentration and the Value effect of Related Party Transactions （RPTs）

引用

Journal of Modern Accounting and Auditing 2013年第2期9卷 239-255页

作者： yaron Amzaleg Ronen Barak Peres Academic Center Rehovot Israel Bar-Ilan University Ramat Gan Israel

This paper investigates 218 related party transactions （RPTs） in Israel, an economy characterized by a high percentage of closely-held finns and identifies a non-linear inverted U connection between the value effect of RPT and the level of finn ownership concentration. This non-linear connection is similar to the worldwide documented quadratic （inverted U） relation between ownership concentration and a finn＇s Tobin＇s Q. The relation becomes even statistically stronger, when measuring ownership concentration using a strategic power approach, in an attempt to identify the source of this puzzling connection.

关键词： related party transaction (RPT) ownership concentration private benefits

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Retrograde intrarenal surgery for lower pole stones utilizing stone displacement technique yields excellent results

引用

Asian Journal of Urology 2023年第1期10卷 58-63页

作者： Dor Golomb Hanan Goldberg Shlomi Tapiero Yariv Stabholz Paz Lotan Abd elhalim Darawsha Ronen Holland yaron e.rlich David Lifshitz Department of Urology Rabin Medical Center-Beilinson HospitalPetach TikvaSackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael Department of Urology State University of New York Upstate Medical UniversitySyracuseNYUSA

Objective:To evaluate the long-term stone-free rate(SFR)of retrograde intrarenal surgery(RIRS)in the treatment of lower pole renal calculi using only basket relocation and identify independent predictors of stone-free ***:All consecutive patients undergoing RIRS lower pole renal calculi at a single highvolume tertiary center were analyzed *** pole stones were relocated to the upper pole,where laser lithotripsy was *** patients were followed up in the clinic following the surgery and yearly *** stone-free status was assessed with a combination of an abdominal ultrasound and abdominal X-ray,or an abdominal non-contrast computed tomography if the stones were known to be ***:A total of 480 consecutive patients who underwent RIRS for treatment of lower pole renal calculi,between January 2012 and December 2018,were analyzed from a prospectively maintained database of 3000 *** a median follow-up time of 18.6 months,the mean SFR was 94.8%.The procedures were unsuccessful in 26(5.4%)patients due to unreachable *** median stone size of the unreachable stones was 12 mm(range 10e30 mm).Multivariable logistic regression analysis revealed two predictors of SFR for lower pole stones:a small cumulative stone burden(odds ratio[OR]:0.903,95%confidence interval[CI]:0.867e0.941,peoperative ureteral stent insertion(OR:0.515,95%CI:0.318e0.835,pZ0.007).Conclusion:The long-term SFR of RIRS for the treatment of lower pole stones with basket displacement with appropriate patient selection is high.

关键词： Ureteroscopy Lower pole stones Retrograde intrarenal surgery Stone-free rate Basketing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

establishing an integrated gastroenterology service between a medical center and the community

引用

World Journal of Gastroenterology 2015年第7期21卷 2152-2158页

作者： yaron Niv Ram Dickman Zohar Levi Gadi Neumann Dorit e.rlich Haim Bitterman Jacob Dreiher Arnon Cohen Doron Comaneshter eyran Halpern Rabin Medical Center Clalit Health Services Tel Aviv University Dan-Petach Tikva District Clalit Health Services General Management Clalit Health Services

AIM:To combine community and hospital services inorder to enable improvements in patient management,an integrated gastroenterology service(IGS)was ***:Referral patterns to specialist clinics were optimized;open access route for endoscopic procedures(including esophago-gastro-duodenoscopy,sigmoidoscopy and colonoscopy)was established;family physicians’knowledge and confidence were enhanced;direct communication lines between experts and primary care physicians were *** education,guidelines and agreed instructions for referral were promoted by the *** quality indicators were developed by the Delphi method,rigorously designed and regularly *** was assessed by comparing 2010,2011 and 2012 ***:An integrated delivery system in a specific medical field may provide a solution to a fragmented healthcare system impaired by a lack of *** this paper we describe a new integrated gastroenterology service established in April *** time for procedures decreased:3 mo in April 30th 2010 to 3 wk in April 30th 2011and stayed between 1-3 wk till December 30th *** cost for patient’s visit decreased from 691 to638 NIS(a decrease of 7.6%).Six health indicators were improved significantly comparing 2010 to 2012,2.5%to 67.5%:Bone densitometry for patients with inflammatory bowel disease,preventive medications for high risk patients on aspirin/NSAIDs,colonoscopy following positive fecal occult blood test,gastroscopy in Barrett’s esophagus,documentation of family history of colorectal cancer,and colonoscopy in patients with a family history of colorectal ***:establishment of an IGS was found to effectively improve quality of care,while being costeffective.

关键词： Gastroenterology Direct referral endoscopy Communi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：