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Wuhan University Journal of Natural Sciences 2006年第6期11卷 1895-1898页

作者： ZHAO yaqun WANG Jue Institute of Information Engineering Information Engineering University Zhengzhou 450002 Henan China State Key Laboratory of Information Security Chinese Academy of Sciences Beijing 100039 China

Orthomorphic permutations have good characteristics in cryptosystems. In this paper, by using of knowledge about relation between orthomorphic permutations and multi-output functions, and conceptions of the generalized Walsh spectrum of multi-output functions and the auto-correlation function of multi-output functions to investigate the Walsh spectral characteristics and the auto-correlation function characteristics of orthormophic permutations, several results are obtained.

关键词： orthomorphic permutation multi-output functions walsh spectral auto-correlation function

Gap junction gene innexin3 being highly expressed in the nervous system and embryonic stage of the mud crab Scylla paramamosain

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Journal of Oceanology and Limnology 2019年第5期37卷 1649-1658页

作者： WANG Shuping CHEN Fangyi ZHANG yaqun MA Xiaowan QIAO Kun State Key Laboratory of Marine Environmental Science College of Ocean & Earth SciencesXiamen UniversityXiamen 361005China State-Province Joint Engineering Laboratory of Marine Bioproducts and Technology Xiamen UniversityXiamen 361005China Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources Xiamen UniversityXiamen 361005China State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China

Innexin proteins are a class of transmembrane proteins existing in invertebrates and they have diverse biological functions. The innexin protein Sp-inx2 has been demonstrated to play roles in immune response and promotion of cell apoptosis in the mud crab Scylla paramamosain . One novel innexin gene, named as Sp-inx3 was characterized from S. paramamosin in this study, with an open reading frame of 1 101 bp encoding 367 amino acid residues. Multiple sequence alignment revealed that the Sp-inx3 is highly homologous with innexin3 of Cancer boredis and Homorus americanus . Quantitative real-time PCR (qPCR) and the western blotting results revealed that Sp-inx3 gene was expressed predominantly in the eyestalk, brain, and thoracic ganglion mass in both female and male crabs. The immunohistochemistry assay (IHC) also showed the widespread and intense immunoreactivity of Sp-inx3 in the brain and thoracic ganglion mass. Sp-inx3 mRNA transcription profi les exhibited signifi cantly higher expression from the embryo1 to embryo4 period and low level of expression at the prehatching period and zoea I larva period of S . paramamosain . These results indicate that the Sp-inx3 may play an important role in the nervous system and early embryonic development of S . paramamosain.

关键词： Scylla paramamosain Sp-inx3 gene expression embryonic development nervous system

基于数据挖掘探究溪黄草药用成分及潜在抗癌的作用机制

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现代医药卫生 2024年第6期40卷 930-935,940页

作者：李小敏张佳涵梁宏轩黄镇江张振霞郑玉忠陈良辉刘亚群韩山师范学院生命科学与食品工程学院广东潮州521041

目的探讨溪黄草的药效成分及其潜在的抗肿瘤作用机制。方法通过文献检索、BATMAN-TCM数据库及CancerHSP数据库收集溪黄草的化学成分,利用化源网查询CAS号,通过TCMSP数据库和SwissADME在线平台筛选有效成分;运用SwissTargetPrediction在... 详细信息

目的探讨溪黄草的药效成分及其潜在的抗肿瘤作用机制。方法通过文献检索、BATMAN-TCM数据库及CancerHSP数据库收集溪黄草的化学成分,利用化源网查询CAS号,通过TCMSP数据库和SwissADME在线平台筛选有效成分;运用SwissTargetPrediction在线平台预测各有效成分的靶点,通过Metascape数据库对靶点进行GO和KEGG富集分析,通过在线作图平台微生信将结果可视化。通过STRING平台获取蛋白互相作用网络并筛选关键靶点,通过NIMNT数据库进行关键靶标的适应证预测,采用网络绘图软件Cytocape3.9.1构建“药物-核心靶标-疾病”互作网络。结果共筛选到5,6,3′,4′-四羟基-7-甲氧基黄酮、铁锈醇、山柰酚和杜鹃黄素等10个有效成分,这些成分作用于212个靶点,其中SRC、PIK3R1、PIK3CA、AKT1、ESR1、CDK1和EGFR等为核心靶点。GO富集分析得到生物过程条目5310条,细胞组成条目524条,分子功能条目981条;KEGG通路富集筛选获得260条信号通路,参与癌症通路、磷酸酶D信号通路和cGMP-PKGX信号通路等多条通路。结论溪黄草抗癌活性是多成分、多靶点、多通路的作用结果,为临床合理使用中草药辅助治疗癌症提供了一定的科学理论依据。

关键词：溪黄草网络药理学靶点信号通路癌症

Three-Dimensional Porous Heterometallic-Organic Frameworks： Synthesis, Luminescent, Magnetic, Adsorption and Hydrogen Storage Properties

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Chinese Journal of Chemistry 2016年第2期34卷 196-202页

作者： yaqun Cao Runwei Wang Gang Wu Qianrong Fang Shilun Qiu State Key Laboratory of Inorganic Synthesis and Preparative Chemistry Jilin University Changchun Jilin 130012 China

Two three-dimensional （3D） porous heterometal-organic frameworks （HMOFs） with isostructures, [Zn2Cd（OH）（BTC）2（DMF）（H20）z].（H30）（JUC-155A） and [ZnCo2（OH）（BTC）z（DMF）（H2O）2].（H3O）（JUC-155B）（JUC = Jilin University China, BTC = 1,3,5-benzenetricarboxylate and DMF = N,N-dimethylformamide）, have been successfully synthesized by utilizing two kinds of 3d metal ions （Zn（II） and Cd（II） or Zn（II） and Co（II）） under conformable conditions. X-ray crystallography reveals that both HMOFs consist of trinuclear metal-carboxylate secon- dary building units （SBUs）, and these SBUs are interlinked by the phenyl groups of BTC ligands to generate 3D open-frameworks with two types of channels of about 6.3 and 10.7 A.. Both HMOFs show the multifunctional prop- erties in photoluminescence and adsorption. JUC-155B also exhibits an antiferromagnetic interaction, owing to the presence of dinuclear cobalt centers. Additionally, the high-pressure hydrogen storage of JUC-155A has been also examined at 77 K. By using mixed metal centers in clustered SBUs, it is a good strategy to construct those isostructures with heterometallic systems, and it is believed that the presence of such HMOFs will further facilitate the exploration ofmultifunctional materials.

关键词： metal-organic framework heterometal-organic framework multifunctional materials porous materials

Mechanistic understanding of the charge storage processes in FeF_(2) aggregates assembled with cylindrical nanoparticles as a cathode material for lithium-ion batteries by in situ magnetometry

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Carbon Energy 2022年第6期4卷 1011-1020页

作者： Zhengqiang Hu Fengling Zhang Huanyu Liang Hao Zhang Huaizhi Wang Tiansheng Wang Renbin Liu Jie Liu Yadong Li Xiaotong Dong Lianyu Bao Zhuan Liang yaqun Wang Shishen Yan Qiang Li Hongsen Li Center for Marine Observation and Communications College of PhysicsQingdao UniversityQingdaoShandongChina College of Electrical Engineering and Automation Shandong University of Science and TechnologyQingdaoShandongChina State Key Laboratory of Crystal Materials School of PhysicsShandong UniversityJinanShandongChina

Transition metal fluorides(TMFs)cathode materials have shown extraordinary promises for electrochemical energy storage,but the understanding of their electrochemical reaction mechanisms is still a matter of debate due to the complicated and continuous changing in the battery internal ***,we design a novel iron fluoride(FeF_(2))aggregate assembled with cylindrical nanoparticles as cathode material to build FeF_(2) lithium-ion batteries(LIBs)and employ advanced in situ magnetometry to detect their intrinsic electronic structure during cycling in real *** results show that FeF_(2) cannot be involved in complete conversion reactions when the FeF_(2) LIBs operate between the conventional voltage range of 1.0–4.0 V,and that the corresponding conversion ratio of FeF_(2) can be further ***,we first demonstrate that the spin-polarized surface capacitance exists in the FeF_(2) cathode by monitoring the magnetic responses over various voltage *** research presents an original and insightful method to examine the conversion mechanism of TMFs and significantly provides an important reference for the future artificial design of energy systems based on spinpolarized surface capacitance.

关键词： charge storage mechanism FeF_(2)cathode materials in situ magnetometry lithium-ion batteries

Separation performance of fine low-rank coal by vibrated gas-solid fluidized bed for dry coal beneficiation

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Particuology 2015年第6期13卷 100-108页

作者： Jingfeng He Yuemin Zhao Jie Zhao Zhenfu Luo Chenlong Duan yaqun He School of Chemical Engineering and Technology Chino University of Mining and Technology Xuzhou 221116 China

Vibrational energy was introduced to a dense medium gas-solid fluidized bed to improve the separation performance of 1-6 mm fine low-rank coal. The setup was termed a vibrated gas-solid fluidized bed and could provide a stable fluidization state and uniform density distribution for dry coal beneficiation by the transfer of vibrational energy and the interaction between vibrations and the gas phase. Favorable segregation of the ash content of the 1-6-ram-sized lignite samples is achieved under suitable operating conditions. Higher yields of cleaning coal were acquired when the ash content was reduced. The probable error values were 0.065 and 0.055 at separating densities of 1.68 and 1.75 g/clTl3 for the 1-3- and 3-6-mm- sized lignite samples, respectively. Effective beneficiation of 1-6-ram-sized fine lignite could be achieved using the vibrated gas-solid fluidized bed, which provides an alternative technique for the separation of fine low-rank coal in arid areas.

关键词： Lignite Vibrational energyGas-solid fluidized bedSegregationSeparation performance

Removal of hydrophobic volatile organic compounds with sodium hypochlorite and surfactant in a co-current rotating packed bed

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Journal of Environmental Sciences 2018年第2期30卷 190-196页

作者： Wenhui Li Haidi Liu Shuangde Li Weiman Li Yunfa Chen Jiajia Gao yaqun Cao State Key Laboratory of Multi-phase Complex Systems Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 China Key Laboratory of Healthy &Intelligent Kitchen System Integration Zhejiang Ningbo 315336 China University of Chinese Academy of Sciences Beijing 100049 China

A co-current flow rotating packed bed was applied to remove volatile organic compounds（VOCs） by sodium hypochlorite（Na Cl O） and surfactant（sodium dodecyl benzene sulfonate,SDBS） from air stream. Xylene was used as a model VOC herein. The effect of p H,concentration of Na Cl O and SDBS solution, liquid flow rate, gas flow rate and rotational speed on xylene removal efficiency and overall mass transfer coefficient（KGa） were discussed. Then, a correlation for KGa of the co-current rotating packed bed was proposed by fitting the experimental data of KGa and independent variables of liquid/gas ratio,rotational speed, p H, Na Cl O concentration and treatment time, which was in good agreement with the experimental data（the deviation ≤ ± 30%）.

关键词： Co-current flow rotating packed bed VOCs Removal efficiency Overall mass transfer coefficient

ICP-AES法和原子荧光法检测硫熏处理对山药中重金属的影响

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现代食品 2024年第11期30卷 147-151,163页

作者：刘亚群陈良辉张勇张慷孙延杰谢耀庆张泽坤郑玉忠张振霞韩山师范学院生命科学与食品工程学院广东潮州521041 广东省粤东药食资源功能物质与治未病研究重点实验室广东潮州521041 右江民族医学院临床医学院广西百色533000

目的:研究硫黄熏蒸对山药中重金属含量的影响,为评估硫黄熏蒸的安全性及山药加工工艺提供科学依据。方法:选取13批不同产地的硫黄对山药进行熏蒸处理,使用微波消解法对样品进行前处理,并通过电感耦合等离子体原子发射光谱法与原子荧光... 详细信息

目的:研究硫黄熏蒸对山药中重金属含量的影响,为评估硫黄熏蒸的安全性及山药加工工艺提供科学依据。方法:选取13批不同产地的硫黄对山药进行熏蒸处理,使用微波消解法对样品进行前处理,并通过电感耦合等离子体原子发射光谱法与原子荧光光谱分析法定量分析硫黄及熏蒸前后山药中汞(Hg)、砷(As)、铜(Cu)、镉(Cd)和铅(Pb)的含量。结果:13批硫黄中Pb、As、Hg含量偏高。硫黄熏蒸后,山药中Pb含量普遍上升,且部分样品中As、Hg和Cu含量亦有增加。结论:硫黄熏蒸可能导致重金属元素从硫黄迁移到山药中,因此应制定严格的硫黄熏蒸工艺规范,确保山药的安全性和质量,减少对人体健康的潜在风险。

关键词：硫黄熏蒸山药重金属电感耦合等离子体发射光谱法原子荧光法

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2010—2021年深圳市ST314肯塔基沙门菌遗传特征和耐药分析

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卫生研究 2024年第2期53卷 243-249,256页

作者：郜晨曦佘艺颖罗苗苗岳芝娇姜伊祥胡璐璐蔡锐江敏吴双石晓路李迎慧邱亚群扈庆华山西医科大学公共卫生学院太原030001 南华大学衡阳421001 深圳市疾病预防控制中心深圳518000

目的了解深圳市ST314肯塔基沙门菌流行情况、遗传特性及耐药特征。方法对2010—2021年深圳市疾病预防控制中心食源性疾病监测网络收集的14株ST314肯塔基沙门菌全基因组测序进行系统发育进化分析、耐药基因及质粒检测;采用微量肉汤法稀... 详细信息

目的了解深圳市ST314肯塔基沙门菌流行情况、遗传特性及耐药特征。方法对2010—2021年深圳市疾病预防控制中心食源性疾病监测网络收集的14株ST314肯塔基沙门菌全基因组测序进行系统发育进化分析、耐药基因及质粒检测;采用微量肉汤法稀释法进行药物敏感性实验。结果共收集57株肯塔基沙门菌,14株为ST314。ST314肯塔基沙门菌全球系统发育树显示,深圳分离株与越南和泰国等东南亚国家的分离株聚集分布在clade 314.2上,且深圳本地菌株间单核苷酸多态性距离较大,说明为散发。在ST314肯塔基沙门菌基因组检测到9类共17个耐药基因/突变,携带3种产超广谱β-内酰胺酶基因,包括bla_(CTX-M-24)(14.3%,2/14)、bla_(CTX-M-55)(7.1%,1/14)、bla_(CTX-M-130)(14.3%,2/14),均位于质粒上。关于喹诺酮类的耐药因子,在基因组中鉴定出2种质粒介导的喹诺酮耐药基因:qnrB6(71.4%,10/14)和aac(6′)Ib-cr(78.6%,11/14),一种喹诺酮耐药决定区突变T57 S(100%,14/14)。深圳市ST314肯塔基沙门菌的多重耐药率为92.86%(13/14),对四环素和复方新诺明的耐药率最高(100%,14/14),其次是氯霉素(92.86%,13/14)、头孢噻肟和氨苄西林(78.57%,11/14)、环丙沙星和萘啶酸(71.43%,10/14),对氨苄西林-舒巴坦的耐药率最低(21.43%,3/14)。结论ST314是深圳市肯塔基沙门菌中的第二大流行的ST型,主要从食品中分离,尤其是禽类;ST314为散发感染,基因组呈现高度的遗传保守型。ST314肯塔基沙门菌耐药十分严重,尤其是喹诺酮耐药决定区突变、喹诺酮耐药基因共同介导的喹诺酮类耐药和质粒介导的头孢类耐药问题突出。

关键词： ST314型肯塔基沙门菌全基因组测序耐药性耐药基因

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激光疏通血管的实验研究

同济医科大学学报 1987年第5期 345-347页

作者：黄厚珍吴亚群刘正湘周燕发王乐徐增绶温中一同济医科大学附属同济医院华中工学院激光研究所

作者自1985年以来进行了153条血管激光疏通实验.最初用不同能量的激光照射100条离体血管,摸索实验方法和参数。此后对活体动物53条血管进行血栓形成实验,成栓率80.6％。接着对其中完全栓塞的20条血管作激光疏通实验,疏通率达85％。

关键词：激光气化疏通偏离散射