检索结果-南通市图书馆

知识溢出对区域创新系统的影响机制研究——基于生命周期的视角

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

工业技术经济 2014年第8期33卷 45-50页

作者：高雅群天津大学天津300000 天津职业大学天津300000

本文的目的是探讨知识溢出在区域创新系统的不同生命周期中产生的作用。本文基于波特的生命周期理论构建了区域创新系统生命周期模型,研究了知识经济条件下高技术产业集群知识溢出对区域创新系统不同生命周期的影响机制。研究结果表明,... 详细信息

本文的目的是探讨知识溢出在区域创新系统的不同生命周期中产生的作用。本文基于波特的生命周期理论构建了区域创新系统生命周期模型,研究了知识经济条件下高技术产业集群知识溢出对区域创新系统不同生命周期的影响机制。研究结果表明,当区域创新系统处于生命周期前3个阶段,知识溢出对创新绩效存在显著、正向的影响;而当区域创新系统进入生命周期的衰退阶段,知识溢出对创新绩效产生负的效应并阻碍了经济主体的创新动力。

关键词：知识溢出高技术产业集群区域创新系统生命周期

Self-powered anti-interference photoelectrochemical immunosensor based on Au/ZIS/CIS heterojunction photocathode with zwitterionic peptide anchoring

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2022年第11期33卷 4750-4755页

作者： Ze Hu yaqun Xu Hao Wang gao-Chao Fan Xiliang Luo Shandong Key Laboratory of Biochemical Analysis College of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China

Accurate detection of important biomarkers with ultra-low levels in complex biological matrix is one of the frontier scientific issues because of possible signal interference of potential reductive agents and protein ***,a self-powered anti-interference photoelectrochemical(PEC)immunosensor was explored for sensitive and specific detection of model target of cardiac troponinⅠ(cTnI).Specifically,a novel ternary heterojunction served as the photocathode to offer a remarkable current output and a zwitterionic peptide was introduced to build a robust antifouling ***(CIS)film with porous network nanostructure was first prepared and then modified in order with ZnInS(ZIS)nanocrystals and Au nanoparticles to fabricate the Au/ZIS/CIS heterojunction *** capture cTnI antibody(Ab)was immobilized,the zwitterionic peptide KAEAKAEAPPPPC was then anchored to compete the *** elaborated PEC immunosensor exhibited high sensitivity for target cTnI antigen(Ag)detection,with good anti-interference against reductive agents and nonspecific *** integration strategy of heterojunction photocathode with zwitterionic peptide provides a new sight to develop advanced PEC immunosensors applying in practical biosamples.

关键词： Photoelectrochemistry Immunoassay Zwitterionic peptide Photocathode Anti-interference

Removal of hydrophobic volatile organic compounds with sodium hypochlorite and surfactant in a co-current rotating packed bed

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2018年第2期30卷 190-196页

作者： Wenhui Li Haidi Liu Shuangde Li Weiman Li Yunfa Chen Jiajia gao yaqun Cao State Key Laboratory of Multi-phase Complex Systems Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 China Key Laboratory of Healthy &Intelligent Kitchen System Integration Zhejiang Ningbo 315336 China University of Chinese Academy of Sciences Beijing 100049 China

A co-current flow rotating packed bed was applied to remove volatile organic compounds（VOCs） by sodium hypochlorite（Na Cl O） and surfactant（sodium dodecyl benzene sulfonate,SDBS） from air stream. Xylene was used as a model VOC herein. The effect of p H,concentration of Na Cl O and SDBS solution, liquid flow rate, gas flow rate and rotational speed on xylene removal efficiency and overall mass transfer coefficient（KGa） were discussed. Then, a correlation for KGa of the co-current rotating packed bed was proposed by fitting the experimental data of KGa and independent variables of liquid/gas ratio,rotational speed, p H, Na Cl O concentration and treatment time, which was in good agreement with the experimental data（the deviation ≤ ± 30%）.

关键词： Co-current flow rotating packed bed VOCs Removal efficiency Overall mass transfer coefficient

Experimental Study of Dissolution-Alteration of Amphibole in a Hydrothermal Environment

在线全文

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2019年第6期93卷 1933-1946页

作者： LI Yongli HUANG Fei gao Wenyuan TANG Xu REN yaqun MENG Lin ZHANG Zhibin Key Laboratory of Ministry of Education on Safe Mining of Deep Metal Mines and School of Resources and Civil EngineeringNortheastern UniversityShenyang 110819China Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Electron Microscope Laboratory Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China

Amphibole is a rock-forming mineral widely existing on the *** is easily dissolved and altered during the later stage of diagenesis and mineralization,and often forms chloritization,which is an important indicator for *** explore amphibole's dissolution process and alteration mechanism,dissolution experiments were carried out under acidic conditions using pargasite-rich amphibole as raw material,and the effects of temperature,p H,and experiment duration on amphibole alteration were *** samples and products were analyzed using X-ray diffractometer,field emission scanning electron microscope,electron probe micro analyzer,and transmission electron *** was found that many pores and erosion edges are produced after amphibole dissolution,and there is a clear interface between the dissolved residual portion and the *** dissolved residual portion remains in the amphibole phase,but as the temperature and time increase,the intensity of the diffraction peak of the phase in the product decreases,and the peak position shifts to a small *** clay minerals such as chlorite and griffithite formed on the amphibole *** an environment with strong acidity(p H=3),the amount of chamosite increases with temperature(180℃→210℃→240℃),whereas clinochlore is only increased in a 150–210℃*** growth was observed in the acidic(p H=6)and low temperature(<180℃)*** on this analysis,large radius Cl–enters the amphibole lattice or cracks to promote *** Al-poor and Ca-and Fe-rich regions between the edge and core of the amphibole are caused by dynamic equilibrium in amphibole dissolution and alteration process,which is an essential indicator for the beginning of amphibole *** and the coupled dissolution-reprecipitation mechanism accomplishes the process of dissolution and alteration to form clay *** energy of the system determined by temperature and p H

关键词： hydrothermal environment amphibole dissolution-alteration chlorite griffithite

Determination of time-and size-dependent fine particle emission with varied oil heating in an experimental kitchen

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2017年第1期29卷 157-164页

作者： Shuangde Li Jiajia gao Yiqing He Liuxu Cao Ang Li Shengpeng Mo Yunfa Chen yaqun Cao State Key Laboratory of Multi-phase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China Key Laboratory of Healthy&Intelligent Kitchen System Integration ZhejiangNingbo315336China University of Chinese Academy of Sciences Beijing 100049China

Particulate matter（PM） from cooking has caused seriously indoor air pollutant and aroused risk to human *** is urged to get deep knowledge of their spatial-temporal distribution of source emission characteristics,especially ultrafine particles（UFP ＆lt; 100 nm） and accumulation mode particles（AMP 100-555 nm）.Four commercial cooking oils are auto dipped water to simulate cooking fume under heating to 255℃ to investigate PM emission and decay features between 0.03 and 10 μm size dimension by electrical low pressure impactor（ELPI） without *** and sunflower produced high PM_（2.5） around5.1 mg/m^3,in comparison with those of soybean and corn（5.87 and 4.55 mg/m^3,respectively）at peak emission time between 340 and 450 sec since heating oil,but with the same level of particle numbers 6-9 × 10~5/cm^*** values of PM_（1.0）/PM_（2.5） and PM_（2.5）/PM_（10） at peak emission time are around 0.51-0.55 and *** 15 min naturally deposition,decay rates of PM_（1.0）,PM_（2.5） and PM_（10） are 13.3%-29.8%,20.1%-33.9%and 41.2%-54.7%,which manifest that PM_（1.0） is quite hard to decay than larger particles,PM_（2.5） and PM_（1.0）.The majority of the particle emission locates at 43 nm with the largest decay rate at 75%,and shifts to a larger size between137 and 555 nm after 15 min *** decay rates of the particles are sensitive to the oil type.

关键词： Cooking fume Ultrafine particle Number concentration Size distribution Emission character

The oxidative DNA damage response： A review of research undertaken with Tsinghua and Xiangya students at the University of Pittsburgh

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2017年第10期60卷 1077-1080页

作者： S.Levine Luxi Sun Rong Tan Ying gao Lu Yang Hao Chen yaqun Teng Li Lan UPMC Hillman Cancer Center Pittsburgh PA 15213 USA Department of Microbiology and Molecular Genetics University of Pittsburgh School of Medicine Pittsburgh PA 15219 USA School of Medicine Tsinghua University Beijing 100084 China Xiangya Hospital Central South University Changsha 410008 China

Endogenous stress and exogenous toxicants(chemicals and UV light) alter genetic information either directly or indirectly through the production of reactive oxygen species(ROS), thereby driving genomic instability in cells and promoting tumorigenesis. All living cells try to faithfully preserve and transmit their genomic information from one generation to the next using DNA repair mechanisms to repair oxidative DNA damage to prevent cancer or premature aging. Oxidative DNA damage comprises a mixture of DNA lesions including base damage, DNA single strand breaks(SSBs), and DNA double strand breaks(DSBs). This review summarizes some of the studies on DNA damage response at a defined genome locus that are performed by students from the Tsinghua University School of Medicine and the School of Medicine of Central South University(Xiangya Hospital) at the University of Pittsburgh School of Medicine. A summary of their work highlights the continuous contribution of the students to a particular research program and exemplifies the achievements of this China-U.S. collaborative training program.

关键词： DNA damage chromatin telomere DNA repair

Activation of G-protein-coupled receptor 39 reduces neuropathic pain in a rat model

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第3期19卷 687-696页

作者： Longqing Zhang Xi Tan Fanhe Song Danyang Li Jiayi Wu Shaojie gao Jia Sun Daiqiang Liu yaqun Zhou Wei Mei Department of Anesthesiology Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Healthand Wuhan Clinical Research Center for Geriatric AnesthesiaTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Activated G-protein-coupled receptor 39(GPR39)has been shown to attenuate inflammation by interacting with sirtuin 1(SIRT1)and peroxisome proliferator-activated receptor-γcoactivator 1α(PGC-1α).However,whether GPR39 attenuates neuropathic pain remains *** this study,we established a Sprague-Dawley rat model of spared nerve injury-induced neuropathic pain and found that GPR39 expression was significantly decreased in neurons and microglia in the spinal dorsal horn compared with sham-operated *** injection of TC-G 1008,a specific agonist of GPR39,significantly alleviated mechanical allodynia in the rats with spared nerve injury,improved spinal cord mitochondrial biogenesis,and alleviated *** changes were abolished by GPR39 small interfering RNA(siRNA),Ex-527(SIRT1 inhibitor),and PGC-1α*** together,these findings show that GPR39 activation ameliorates mechanical allodynia by activating the SIRT1/PGC-1αpathway in rats with spared nerve injury.

关键词： G-protein-coupled receptor 39(GPR39) neuroinflammation neuropathic pain nuclear respiratory factor 1(NRF1) peroxisome proliferator-activated receptor-γcoactivator 1α(PGC-1α) sirtuin 1(SIRT1) spinal cord mitochondrial transcription factor A(TFAM)

在线全文

学校读者我要写书评

暂无评论

基于PWM波形特征的励磁涌流识别方法

电力自动化设备 2018年第9期38卷 135-140页

作者：胡松江亚群黄纯高云鹏湖南大学电气与信息工程学院湖南长沙410082

在分析励磁涌流与区内故障电流波形特征差异的基础上,提出了一种利用调制得到脉冲宽度调制(PWM)波形特征来识别励磁涌流的方法。分析了利用励磁涌流调制得到PWM波形与利用故障电流调制得到PWM波形的差异,设置了2个判据来识别励磁涌流和... 详细信息

在分析励磁涌流与区内故障电流波形特征差异的基础上,提出了一种利用调制得到脉冲宽度调制(PWM)波形特征来识别励磁涌流的方法。分析了利用励磁涌流调制得到PWM波形与利用故障电流调制得到PWM波形的差异,设置了2个判据来识别励磁涌流和区内故障电流。所提方法原理简单,灵敏性好,具有一定抗电流互感器饱和能力,可靠性高。MATLAB仿真结果表明,所提方法可准确、快速识别各种情况下的励磁涌流和变压器区内故障电流。

关键词：励磁涌流变压器区内故障调制法 PWM波形

输电线路两相短路故障的自适应分相重合闸方法

在线全文

学校读者我要写书评

暂无评论

湖南大学学报（自然科学版） 2018年第4期45卷 82-88页

作者：江亚群洪俊宇黄纯高云鹏江辉湖南大学电气与信息工程学院湖南长沙410082 深圳大学光电工程学院广东深圳518060

针对不带并联电抗器的超高压输电线路上发生的两相短路故障,提出一种自适应分相重合闸方法.搭建两相短路故障分析电路模型,推导出瞬时性故障下不同阶段选跳相端电压的时域表达式,分析选跳相端电压特性.研究发现,瞬时性故障二次电弧熄弧... 详细信息

针对不带并联电抗器的超高压输电线路上发生的两相短路故障,提出一种自适应分相重合闸方法.搭建两相短路故障分析电路模型,推导出瞬时性故障下不同阶段选跳相端电压的时域表达式,分析选跳相端电压特性.研究发现,瞬时性故障二次电弧熄弧时,选跳相断路器两端电压的相角差由-120°突变到180°,且熄弧后恢复电压中出现明显的衰减直流分量.利用选跳相端电压的上述特征,提出了二次电弧熄灭时刻捕捉判据,实现了超高压输电线路上的自适应分相重合闸,并通过仿真验证了分析结果的正确性及所提方法的有效性.

关键词：输电线路自适应重合闸分相重合闸瞬时性故障故障分析