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Precision regulation of plant aromatic amino acid homeostasis

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Science China(Life Sciences) 2024年第6期67卷 1316-1317页

作者： Jie luo Yazhouwan National Laboratory(YNL) Sanya 572025China School of Breeding and Multiplication(Sanya Institute of Breeding and Multiplication) Hainan UniversitySanya 572025China

The aromatic amino acids(AAAs)phenylalanine(Phe),tyrosine(Tyr),and tryptophan(Trp)are not only building blocks of proteins,but also precursors of numerous primary and specialized metabolites(Schenck and Maeda,2018).For instance,Trp is a precursor of the phytohormone auxin and the plant defense compounds indole glucosinolates,while Phe serves as a precursor of lignin,coumarin and *** plant natural products such as morphine and vitamin E are derived from Tyr,and have been employed in human medicine and nutrition(Schenck and Maeda,2018;Wu et al.,2022;Yokoyama et al.,2021).

关键词： aromatic instance coumarin

The effects of experimental pain on pain-related words recognition under controlled processing and automatic processing

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The effects of experimental pain on pain-related words recog...

In Situ Polymer Gel Electrolyte in Boosting Scalable Fibre Lithium Battery Applications

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Yanlin luo,yaqi SHI,Xueyan FENG,Xin DOU,Yuexiu LI,Junfa LI~* Department of neurobiology,the Capital Medical University,Beijing 100069,China

＜正＞Aims The effect of experimental moderate pain induced by the tourniquet inflation around the upper limb on the recognition of pain-related words under controlled processing or automatic processing and the difference between them were investigated in this *** 32 healthy college students aged from 18 to 22（21.81±2.24） years old including 16 males and 16 females participated in this *** tourniquet was tied to one side upper limb of subjects 1cm above Cubits horizontal *** tourniquet inflation,all subjects were asked to finish the Dot-probe tasks with five kinds of words（affective,sensory,positive,social threat and neutral） by contralateral *** tourniquet was inflated to 200 mmHg and kept this pressure until subjects completed the Dot-probe *** experiment 1,the words were displayed for 100ms in the Dot-probe task,and the words can’t be perceived by subjects. In experiment 2,the words were displayed for 1000 ms,and the words can be *** reaction time and the error rate of recognition task were recorded,and the reformed McGill Pain Questionnaire（MPQ） was filled by subjects after *** Pain intensity during tasks measured by reformed MPQ showed that moderate pain was induced by tourniquet inflation to 200 mmHg（4.81±1.6）.The data of the reaction time with one factor of displaying time,and another factor of five kinds of words were analyzed by two-way measures analysis of variance（ANOVA）.The results showed that a significant difference was found in the main effect in reaction time between controlled processing and automatic processing（P = 0.027）.Reaction time under automatic processing（481±65 ms） is significantly longer than that of controlled processing（464±70 ms）.Compared automatic processing（476±63 ms） with controlled processing （454±62 ms）,male react more quickly（P = 0.032）.Such difference was not found in ***-way ANOVA for the error rate showed no significant difference in the main effect（P = 0.169）.The data of t

关键词： sex difference tourniquet pain word recognition attentional bias automatic processing

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Nano-Micro Letters 2024年第11期16卷 170-173页

作者： Jie luo Qichong Zhang Key Laboratory of Multifunctional Nanomaterials and Smart Systems Chinese Academy of SciencesSuzhou Institute of Nano-Tech and Nano-Bionics398 Ruoshui RoadSuzhou 215123People’s Republic of China

The poor interfacial stability not only deteriorates fibre lithium-ion batteries(FLBs)performance but also impacts their scalable *** efficiently address these challenges,*** Peng team proposed a generalized channel structures strategy with optimized in situ polymerization technology in their recent *** resultant FLBs can be woven into different-sized powering textiles,providing a high energy density output of 128 Wh kg^(-1) and simultaneously demonstrating good durability even under harsh *** a promising strategy expands the horizon in developing FLB with particular polymer gel electrolytes,and significantly ever-deepening understanding of the scaled wearable energy textile system toward a sustainable future.

关键词： High-performance fibre lithium batteries Gel electrolytes Channel structures Stable interface Scalable application

Catalyst design and structure control for photocatalytic refineries of cellulosic biomass to fuels and chemicals

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Journal of Energy Chemistry 2024年第7期94卷 102-127页

作者： Lulu Sun Nengchao luo State Key Laboratory of Catalysis Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina

Lignocellulosic biomass is the largest renewable hydrocarbon resource on *** cellulose,one of the major components of lignocellulose,powered by solar energy is a promising way of providing lowcarbon-footprint energy chemicals such as H_(2),HCOOH,CO,and transportation ***-of-the-art biorefineries target the full use of biomass feedstocks as they have a maximum collection radius of 75-100 km,requesting efficient and selective photocatalysts that significantly influence the outcome of photocatalytic ***-performed photocatalysts can harvest a broad solar spectrum and are active in breaking the chemical bonds of cellulose,decreasing the capital investments of ***,photocatalysts should control the selectivity of cellulose conversion,originating target products to level down separation *** separation in photocatalysts and interfacial charge transfer between photocatalysts and cellulose affect the activity and selectivity of cellulose refineries to H2 and carbonaceous *** account for the challenges above,this review summarizes photocatalysts for the refineries of cellulose and downstream platform molecules based on the types of products,with the structure features of different types of photocatalysts discussed in relation to the targets of either improving the activity or product *** addition,this review also sheds light on the methods for designing and regulating photocatalyst structures to facilitate photocatalytic refineries of cellulose and platform molecules,meanwhile summarizing proposed future research challenges and opportunities for designing efficient photocatalysts.

关键词： Photocatalysts Biorefineries Cellulose Fuels Hydrogen

Detecting APT-Exploited Processes through Semantic Fusion and Interaction Prediction

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Computers, Materials & Continua 2024年第2期78卷 1731-1754页

作者： Bin luo Liangguo Chen Shuhua Ruan Yonggang luo School of Cyber Science and Engineering Sichuan UniversityChengdu610065China Key Laboratory of Data Protection and Intelligent Management(Sichuan University) Ministry of EducationChengdu610065China Cyber Science Research Institute Sichuan UniversityChengdu610065China

Considering the stealthiness and persistence of Advanced Persistent Threats(APTs),system audit logs are leveraged in recent studies to construct system entity interaction provenance graphs to unveil threats in a ***-based provenance graph APT detection approaches require elaborate rules and cannot detect unknown attacks,and existing learning-based approaches are limited by the lack of available APT attack samples or generally only perform graph-level anomaly detection,which requires lots of manual efforts to locate attack *** paper proposes an APT-exploited process detection approach called ThreatSniffer,which constructs the benign provenance graph from attack-free audit logs,fits normal system entity interactions and then detects APT-exploited processes by predicting the rationality of entity ***,ThreatSniffer understands system entities in terms of their file paths,interaction sequences,and the number distribution of interaction types and uses the multi-head self-attention mechanism to fuse these ***,based on the insight that APT-exploited processes interact with system entities they should not invoke,ThreatSniffer performs negative sampling on the benign provenance graph to generate non-existent edges,thus characterizing irrational entity interactions without requiring APT attack *** last,it employs a heterogeneous graph neural network as the interaction prediction model to aggregate the contextual information of entity interactions,and locate processes exploited by attackers,thereby achieving fine-grained APT *** results demonstrate that anomaly-based detection enables ThreatSniffer to identify all attack *** to the node-level APT detection method APT-KGL,ThreatSniffer achieves a 6.1%precision improvement because of its comprehensive understanding of entity semantics.

关键词： Advanced persistent threat provenance graph multi-head self-attention graph neural network

THE GRADIENT ESTIMATE OF SUBELLIPTIC HARMONIC MAPS WITH A POTENTIAL

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Acta Mathematica Scientia 2024年第4期44卷 1189-1199页

作者： Han luo School of Mathematical Sciences Fudan UniversityShanghai 200433China

In this paper,we investigate subelliptic harmonic maps with a potential from noncompact complete sub-Riemannian manifolds corresponding to totally geodesic Riemannian *** some suitable conditions,we give the gradient ... 详细信息

关键词： sub-Riemannian manifolds subelliptic harmonic maps with potential gradient estimate Liouville Theorem

Single-cell RNA sequencing in juvenile idiopathic arthritis

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Genes & Diseases 2024年第2期11卷 633-644页

作者： Xiwen luo Xuemei Tang Department of Rheumatology and Immunology Children’s Hospital of Chongqing Medical UniversityChongqing 400014China Chongqing Key Laboratory of Child Infection and Immunity Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChildren's Hospital of Chongqing Medical UniversityChongqing 400014China

Juvenile idiopathic arthritis (JIA) is one of the most common chronic inflammatory rheumatic diseases in children,with onset before age 16 and lasting for more than 6 *** is a highly heterogeneous condition with various consequences for health and quality of *** some JIA patients,early detection and intervention remain *** a result,further investigation of the complex and unknown mechanisms underlying JIA is *** in technology now allow us to describe the biological heterogeneity and function of individual cell populations in *** this review,we hope to provide novel ideas and potential targets for the diagnosis and treatment of JIA by summarizing the current findings of single-cell RNA sequencing studies and understanding how the major cell subsets drive JIA pathogenesis.

关键词： Juvenile idiopathic arthritis Macrophage Macrophage activation syndrome Monocyte Single-cell RNA sequencing Synoviocyte T cell

A Self-Attention Based Dynamic Resource Management for Satellite-Terrestrial Networks

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China Communications 2024年第4期21卷 136-150页

作者： Lin Tianhao luo Zhiyong School of Electronics and Communication Engineering Sun Yat-Sen UniversityShenzhen 518107China Peng Cheng Laboratory Shenzhen 518107China

The satellite-terrestrial networks possess the ability to transcend geographical constraints inherent in traditional communication networks,enabling global coverage and offering users ubiquitous computing power support,which is an important development direction of future *** this paper,we take into account a multi-scenario network model under the coverage of low earth orbit(LEO)satellite,which can provide computing resources to users in faraway areas to improve task processing ***,LEO satellites experience limitations in computing and communication resources and the channels are time-varying and complex,which makes the extraction of state information a daunting ***,we explore the dynamic resource management issue pertaining to joint computing,communication resource allocation and power control for multi-access edge computing(MEC).In order to tackle this formidable issue,we undertake the task of transforming the issue into a Markov decision process(MDP)problem and propose the self-attention based dynamic resource management(SABDRM)algorithm,which effectively extracts state information features to enhance the training *** results show that the proposed algorithm is capable of effectively reducing the long-term average delay and energy consumption of the tasks.

关键词： mobile edge computing resource management satellite-terrestrial networks self-attention

Theoretical Design of Defects as a Driving Force for Ion Transport in Li_(3)OBr Solid Electrolyte

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Energy & Environmental Materials 2024年第3期7卷 143-153页

作者： Xingyun luo Yanlu Li Xian Zhao State Key Lab of Crystal Materials and Institute of Crystal Materials Shandong UniversityJinan 250100China Center for Optics Research and Engineering Shandong UniversityQingdao 266237China

Due to ever-increasing concerns about safety issues in using Li ionic batteries,solid electrolytes have extensively *** Li-rich antiperovskite Li_(3)OBr has been considered as a promising solid electrolyte candidate,but it still suffers challenges to achieve a high ionic conductivity owing to the high intrinsic symmetry of the crystal ***,we presented a design strategy that introduces various point defects and grain boundaries to break the high lattice symmetry of Li_(3)OBr crystal,and their effect and microscopic mechanism of promoting the migration of Li-ion were explored *** has been found that Li_(i)are the dominant defects responsible for the fast Li-ion diffusion in bulk Li_(3)OBr and its surface,but they are easily trapped by the grain boundaries,leading to the annihilating of the Frenkel defect pair V'_(Li)+Li_(i),and thus limits the V'_(Li)diffusion at the grain *** V_(Br)defect near the grain boundaries can effectively drive V'_(Li)across the grain boundary,thereby converting the carrier of Li^(+)migration from Li,in the bulk and surface to V'_(Li)at the grain boundary,and thus improving the ionic conductivity in the whole Li_(3)OBr *** work provides a comprehensive insight into the Li^(+)transport and conduction mechanism in the Li_(3)OBr *** opens a new way of improving the conductivity for all-solid-state Li electrolyte material through the defect design.

关键词： defects density functional theory ionic migration solid electrolyte