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FoxO1基因对家畜肌肉发育、脂肪沉积及生殖细胞发育的调控作用研究进展

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中国畜牧杂志 2025年第2期61卷 70-75页

作者：张久盘姜超宋雅萍宋小雨魏大为宁夏农林科学院动物科学研究所宁夏草畜工程技术研究中心宁夏大学动物科技学院宁夏反刍动物分子细胞育种重点实验室

FoxO1(Forkhead Box O 1)基因是Forkhead Box O亚家族5个成员中最早被鉴定的一员，其转录活性受磷酸化、乙酰化、甲基化和泛素化等修饰调节后，参与细胞凋亡、细胞周期、氧化应激、细胞分化、细胞代谢的调节，在家畜肌肉发育、脂肪沉积... 详细信息

FoxO1(Forkhead Box O 1)基因是Forkhead Box O亚家族5个成员中最早被鉴定的一员，其转录活性受磷酸化、乙酰化、甲基化和泛素化等修饰调节后，参与细胞凋亡、细胞周期、氧化应激、细胞分化、细胞代谢的调节，在家畜肌肉发育、脂肪沉积及生殖细胞发育中发挥重要作用。本文综述了FoxO1基因的分类命名、结构功能及其在家畜肌肉发育、脂肪沉积和生殖细胞发育中的调控作用，以期为深层次理解家畜肉品质形成机理、新品种培育以及疾病的诊疗提供理论参考。

关键词： FoxO1基因家畜肌肉发育脂肪沉积生殖细胞发育

Multi-Feature Fusion-Guided Multiscale Bidirectional Attention Networks for Logistics Pallet Segmentation

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Computer Modeling in Engineering & Sciences 2022年第6期131卷 1539-1555页

作者： Weiwei Cai yaping song Huan Duan Zhenwei Xia Zhanguo Wei School of Logistics and Transportation Central South University of Forestry and TechnologyChangsha410004China Graduate School Northern Arizona UniversityFlagstaffAZ 86011USA

In the smart logistics industry,unmanned forklifts that intelligently identify logistics pallets can improve work efficiency in warehousing and transportation and are better than traditional manual forklifts driven by ***,they play a critical role in smart warehousing,and semantics segmentation is an effective method to realize the intelligent identification of logistics ***,most current recognition algorithms are ineffective due to the diverse types of pallets,their complex shapes,frequent blockades in production environments,and changing lighting *** paper proposes a novel multi-feature fusion-guided multiscale bidirectional attention(MFMBA)neural network for logistics pallet *** better predict the foreground category(the pallet)and the background category(the cargo)of a pallet image,our approach extracts three types of features(grayscale,texture,and Hue,Saturation,Value features)and fuses *** multiscale architecture deals with the problem that the size and shape of the pallet may appear different in the image in the actual,complex environment,which usually makes feature extraction *** study proposes a multiscale architecture that can extract additional semantic ***,since a traditional attention mechanism only assigns attention rights from a single direction,we designed a bidirectional attention mechanism that assigns cross-attention weights to each feature from two directions,horizontally and vertically,significantly improving ***,comparative experimental results show that the precision of the proposed algorithm is 0.53%–8.77%better than that of other methods we compared.

关键词： Logistics pallet segmentation image segmentation multi-feature fusion multiscale network bidirectional attention mechanism HSV neural networks deep learning

Cationic and Anionic Antimicrobial Agents Co‑Templated Mesostructured Silica Nanocomposites with a Spiky Nanotopology and Enhanced Biofilm Inhibition Performance

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Nano-Micro Letters 2022年第5期14卷 181-191页

作者： yaping song Qiang Sun Jiangqi Luo Yueqi Kong Bolin Pan Jing Zhao Yue Wang Chengzhong Yu Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbaneQLD 4072Australia Centre for Microscopy and Microanalysis University of QueenslandBrisbaneQLD 4072Australia Australia Centre for Water and Environmental Biotechnology University of QueenslandBrisbaneQLD 4072Australia School of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200241People’s Republic of China

Silica-based materials are usually used as delivery systems for antibacterial *** rare cases,bactericidal cationic surfactant templated silica composites have been reported as antimicrobial ***,their antibacterial efficacy is limited due to limited control in content and ***,we report a“dual active templating”strategy in the design of nanostructured silica composites with intrinsic antibacterial *** strategy uses cationic and anionic structural directing agents as dual templates,both with active antibacterial *** cationic-anionic dual active templating strategy further contributes to antibacterial nanocomposites with a spiky *** controllable release of dual active antibacterial agents,the spiky nanocomposite displays enhanced anti-microbial and anti-biofilm properties toward Staphylococcus *** findings pave a new avenue toward the designed synthesis of novel antibacterial nanocomposites with improved performance for diverse antibacterial applications.

关键词： Antibacterial surfactants Spiky nanoparticles Antibacterial Anti-biofilm Mesostructured nanocomposites

First principle calculation of lithiation/delithiation voltage in Li-ion battery materials

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Chinese Science Bulletin 2011年第30期56卷 3229-3232页

作者： ZHU XiaoHui CHEN Ning LIAN Fang song yaping LI Yang School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China Department of Engineering Science and Materials University of Puerto Rico Mayaguez PR 00681-9044 USA

A first principle method, based on the density functional theory, was used to investigate the average voltage of lithiation/delithiation for Li-ion battery materials across 7 categories and 18 series, including LiMO 2 , LiMn 2 O 4 , LiMPO 4 , Li 2 MSiO 4 and graphite. The average voltage of lithiation/delithiation in the relevant electrode materials was obtained by comparing the total-energy difference, before and after an electrochemical reaction. The calculated values were in good agreement with experimental data. The systematic difference between the simulated and experimental values could be explained in terms of the binding energy on the surface of the lithium electrode. This type of calculation method could be applied as an easy and effective tool for predicting the potential performance of new lithiation/delithiation materials.

关键词：第一原理计算电池材料平均电压锂离子锂化 LiMn204 密度泛函理论电化学反应

Construction of isolated Ni sites on nitrogen-doped hollow carbon spheres with Ni-N_(3) configuration for enhanced reduction of nitroarenes

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Nano Research 2022年第7期15卷 6001-6009页

作者： Binbin Feng Rou Guo Qiulan Cai yaping song Nan Li Yanghe Fu De-Li Chen Jiangwei Zhang Weidong Zhu Fumin Zhang Key Laboratory of the Ministry of Education for Advanced Catalysis Materials Institute of Physical ChemistryZhejiang Normal UniversityJinhua 321004China Dalian National Laboratory for Clean Energy&State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China

Designing and synthesizing high-efficiency non-precious metal-based catalysts having uniform active sites increases the reactivity and selectivity of materials and provides a platform for an in-depth understanding of their catalytic reaction *** this study,we provided an approach for fabricating isolated nickel single-atom sites(Ni SAs)with high loading(4.9 wt.%)stabilized on nitrogen-doped hollow carbon spheres(NHCS)using a core–shell structured Zn/Ni bimetallic zeolitic imidazolate framework(ZIF)composite as the sacrificial *** as-fabricated Ni SAs/NHCS catalyst shows superior activity,selectivity,and recycling durability for the catalytic transfer hydrogenation of nitrobenzene to aniline,thus achieving 100%yield of aniline with a turn-over frequency(TOF)value as high as 29.9 h^(−1) under mild *** TOF value is considerably superior to the supported Ni nanoparticle *** experiments designed show that the hollow structure feature of NHCS facilitates accessible active sites and mass transfer,which thus contributes to the enhancement of the catalytic performance of Ni SAs/*** functional theory calculations show the high chemo-selectivity and activity of the Ni SAs catalyst,arising from the unique role of the single Ni-N3 site on simultaneously activating the H donor(N_(2)H_(4))and substrate,as well as the hydrogenation of the–NOH group as the rate-determining step.

关键词： single-atom catalyst chemo-selective reduction nitro compounds aromatic amines

A core–shell-structured zeolitic imidazolate framework@cationic antimicrobial agent templated silica nanocomposite for tackling antibiotic resistant bacteria infection

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Aggregate 2024年第3期5卷 397-408页

作者： Qihui Kan yaping song Yining Yao Jun Zhang He Xian Dan Cheng Yue Wang Liang Mao Meiyan Wang Chengzhong Yu State Key Laboratory of Pollution Control and Resource Reuse School of the EnvironmentNanjing UniversityNanjingChina Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbaneQueenslandAustralia School of Chemistry and Molecular Engineering East China Normal UniversityShanghaiP.R.China School of Life Sciences East China Normal UniversityShanghaiP.R.China

Bacterial infection is a major threat to public *** offers a solu-tion by combining nanomaterials with antibacterial *** development of an effective nanocomposite against drug-resistant bacteria such as methicillin-resistant Staphylococcus aureus(MRSA)is highly important yet ***,an anti-MRSA core–shell structure is designed,containing antibacterial zeolitic imidazolate framework-8(ZIF-8)as the core and bactericidal benzalkonium chloride(BAC)templated rough-surface mesostructured silica nanocomposite(RMSN)as the *** resultant ZIF-8@RMSN nanocomposite exhibits sustained release of BAC and zinc ions,effective disruption of the bacterial membrane,generation of oxidative damage of bacterial DNA,leakage of intracellular components,andfinally bacte-rial ***,the synergistic antibacterial mechanisms lead to enhanced biofilm elimination *** addition,the ZIF-8@RMSN-modified band-aid effectively combats MRSA infection in *** work has provided a promising nanocomposite against MRSA-related infections.

关键词： benzalkonium chloride core–shell structure mesoporous silica metal organic framework methicillin-resistant Staphylococcus aureus

Universal design of three-dimensional porous graphene-iron based promotors for kinetically rationalized lithium-sulfur chemistry

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Journal of Energy Chemistry 2025年第1期100卷 192-200页

作者： Hua Gao Yunfeng Zhang Menglei Wang Ruoxuan Yang Shuai Feng Xuan Cao yaping Zhang Zhongyuan Lu Yingze song State Key Laboratory of Environment-Friendly Energy Materials School of Materials and ChemistrySouthwest University of Science and TechnologyMianyang 621010SichuanChina School of Material Science and Engineering Henan University of TechnologyZhengzhou 450001HenanChina College of Chemistry and Chemical Engineering Taishan UniversityTai’an 271021ShandongChina

Lithium-sulfur(Li-S)batteries are widely deemed to be one of the most potential candidates for future secondary batteries because of their remarkable energy ***,notorious polysulfide shuttling and retarded sulfur reaction kinetics pose significant obstacles to the further application of Li-S *** rationally designed highly active electrocatalysts can facilitate polysulfide conversion,the universal and scalable synthesis strategies need to be ***,a universal synthetic strategy to construct a series of three-dimensional(3D)porous graphene-iron(3DGr-Fe)based electrocatalysts involving 3DGr-FeP,3DGr-Fe_(3)C,and 3DGr-Fe_(3)Se_(4)is exploited for manipulating the Li-S redox *** has been observed that the implementation of a 3D porous Gr architecture leads to the well-designed conductive networks,while the uniformly dispersed iron nanoparticles introduce an abundance of active sites,fostering the lithium polysulfide conversion,thereby bolstering the overall electrochemical *** Li-S battery with the 3DGr-Fe based electrocatalyst exhibits remarkable capacity retention of 94.8%upon 100 times at 0.2 ***,the soft-packaged Li-S pouch cell based on such a 3DGr-Fe electrocatalyst delivers superior capacity of 1060.71 mA h g^(-1)and guarantees for the continuous 30 min work of fan *** investigation gives comprehensive insights into the design,synthesis,and mechanism of 3DGr-Fe based electrocatalysts with high activity toward efficient and durable Li-S batteries.

关键词： Lithium-sulfur battery Universal synthesis 3D graphene-iron based promotor Electrocatalysis

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“县域经济”到底是什么？

江汉论坛 2009年第5期 5-12页

作者：宋亚平湖北省社会科学院院长、党组副书记湖北武汉430077

自从党的十六大报告明确提出发展和壮大县域经济的战略任务之后,对于"县域经济"概念的理解和说法很多,可谓是"仁者见仁、智者见智"。在很多专家学者看来,县域经济就是特色经济。实际上,经济活动的特色化,既是县域生产要素差异性所自然... 详细信息

自从党的十六大报告明确提出发展和壮大县域经济的战略任务之后,对于"县域经济"概念的理解和说法很多,可谓是"仁者见仁、智者见智"。在很多专家学者看来,县域经济就是特色经济。实际上,经济活动的特色化,既是县域生产要素差异性所自然形成的本质特征,也是县域经济得以超越常规发展的必然要求。虽然百花齐放、百家争鸣的方法对于学术研究来讲十分必要,但这种众说纷纭、莫衷一是的混乱,却往往容易让那些在县域前沿从事具体操作的基层干部陷入"云里雾里"而迷失方向,影响甚至伤害县域经济的健康发展。笔者根据自己在县域担任党政主职和领导经济工作多年的经验,谈谈个人的一些体会与感想,以供同志们参考。

关键词：县域经济特色经济开放经济政府职能

高校一流本科教育政策内容量化评价与优化--基于PMC指数模型的分析

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教育发展研究 2021年第9期41卷 12-20,36页

作者：宋亚萍西安交通大学公共政策与管理学院西安710049

一流本科教育政策是本科教育提质增效的行动指南,对相关政策的评价可以为政策制定、调整和完善提供参考。研究结合文本挖掘与内容分析法,通过构建PMC指数模型对8所高校一流本科教育政策文本进行量化评价,结果发现:(1)各校政策在政策性... 详细信息

一流本科教育政策是本科教育提质增效的行动指南,对相关政策的评价可以为政策制定、调整和完善提供参考。研究结合文本挖掘与内容分析法,通过构建PMC指数模型对8所高校一流本科教育政策文本进行量化评价,结果发现:(1)各校政策在政策性质、政策重点、政策受众、政策功能、政策视角、政策指向和政策文件引用等方面的一致性程度较高;(2)政策设计总体较为合理,共有7项政策等级评价为优秀,1项为可接受,无不良和完美级政策,且在政策重点、政策功能、政策视角和政策文件引用方面优势明显;(3)样本政策存在政策指向结构性失衡、政策目标设置不合理、政策科学性有待提高、政策保障激励有效性难以发挥等问题。文章针对上述问题提出优化建议。

关键词：一流本科教育 PMC指数政策评价量化研究