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Development of new beam current transformer based on TMR

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Radiation Detection Technology and Methods 2019年第3期3卷 268-273页

作者： Ying Zhao yaoyao du Lin Wang Jianshe Cao Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Key Laboratory of Particle Acceleration Physics and Technology Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China

Purpose and background As the magneto-resistor technology is developed,applying it to beam instrumentation for the accelerator becomes *** this paper,a new principle beam current sensor based on TMR linear sensor is *** Feasibility research by simulation and calculation has been done,a study of the critical component for the whole system has been carried out,and all these are presented in this *** and conclusions Laboratory test results include the nonlinear error,and resolution analysis is *** work plan for the next step of the improvement and upgrade is also referred to.

关键词： Beam current Magneto-resistor CST

ADAMTS-7 promotes vascular smooth muscle cells proliferation in vitro and in vivo

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Science China(Life Sciences) 2015年第7期58卷 674-681页

作者： ZHANG Lu YU Fang WANG Li ZHENG JinGang du yaoyao HUANG YaQian LIU Bo WANG Xian KONG Wei Department of Physiology and Pathophysiology School of Basic Medical Sciences Peking University Key Laboratory of Molecular Cardiovascular Science Ministry of Education Department of Cardiology China-Japan Friendship Hospital

Vascular smooth muscle cell(VSMC) proliferation and migration are pivotal for the pathogenesis of atherosclerosis and post-angioplasty restenosis. We have recently reported that a disintegrin and metalloproteinase with thrombospondin motifs-7(ADAMTS-7), a novel metalloproteinase, contributes directly to neointima formation by mediating VSMC migration. However, whether ADAMTS-7 affects VSMC proliferation remains unclear. In this study, we found that luminal adenoviral delivery of ADAMTS-7 aggravated intimal hyperplasia 7 d after injury, paralleled by an increased percentage of PCNA-positive cells in both intima and media. In contrast, perivascular administration of ADAMTS-7 si RNA, but not scrambled si RNA to injured arteries attenuated intimal thickening at day 7, paralleled with reduced intimal VSMC replication, without alteration of VSMC proliferation in the media. In accordance, [3H]-thymidine incorporation assay in primary cultured rat VSMCs revealed an enhanced replication rate(by 61%) upon ADAMTS-7 overexpression and retarded proliferation(by 23%) upon ADAMTS-7 si RNA administration. Our data demonstrates that ADAMTS-7 promotes VSMC proliferation both in vitro and in vivo. ADAMTS-7 may therefore serve as a novel therapeutic target for atherosclerosis and post-angioplasty restenosis.

关键词： vascular smooth muscle cell ADAMTS-7 proliferation

Electro-mechanical offset measurements of beam position monitors

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Radiation Detection Technology and Methods 2023年第2期7卷 288-296页

作者： Jun He Yanfeng Sui Yong Li yaoyao du Linda Yu Junhui Yue Jianshe Cao Xujian Wang Zhe duan Ouzheng Xiao Key Laboratory of Particle Acceleration Physics and Technology Institute of High Energy PhysicsChinese Academy of SciencesBeijing100049China University of Chinese Academy of Sciences Beijing100049China

Purpose The absolute beam position measurement in the booster and storage ring of the high energy photon source(HEPS)requires the offset between the electrical and mechanical centers of the beam position monitor(BPM).Method Traditionally,an RF signal is sent to an antenna or stretched wire aligned with the vacuum chamber,and the signal at each electrode is ***,a replacement method using a vector network analyzer,which was proposed by Lambertson,does not involve mechanical alignment and can be used for electrical offset *** and conclusions The electro-mechanical offsets of booster BPMs of the HEPS were measured using the Lambertson *** result shows good agreement with the stretched wire method within a 30μm error.

关键词： Beam position monitor Mechanical center HEPS Electro-mechanical offsets

Automatic test system development for digital beam position monitor of HEPS and BEPCII

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Radiation Detection Technology and Methods 2022年第3期6卷 330-338页

作者： Xuhui Tang yaoyao du Jianshe Cao Shujun Wei Zhi Liu Qiang Ye Huizhou Ma Jing Yang Guodong Gao Yukun Li Yanfeng Sui Junhui Yue University of Chinese Academy of Science Beijing 100049China Institute of High Energy Physics Chinese Academy of ScienceBeijing 100049China

Purpose Hundreds of digital beam position monitor processors(DBPM)are required to be produced during the construction of projects such as High Energy Photon Source(HEPS)and the upgrade project of the Beijing Electron Positron Collider(BEPCII),which brings great challenges to the test *** order to achieve accurate,fast,and complete mass production tests of DBPMs,an automatic test system(ATS)has been developed in this *** According to the test items of DBPM,the standardized testing softwareﬂow is designed based on virtual instru-ment program control technology and experimental physics and industrial control system(EPICS),which realize automatic adjustment of test parameters and automatic acquisition of test result *** and conclusions The ATS can realize one-button testing of channel coefﬁcients,channel linearity,attenuator linearity,beam current dependence(BCD)and sampling signal-to-noise ratio(SNR),and generate test *** total test time is less than 3 minutes,which is signiﬁcantly more efﬁcient compared to manual *** than 90 BEPCII DBPMs has been tested by this ATS in the *** test results proved that such a system could automatically recognize defective products and satisfy the requirements of mass testing.

关键词： Automatic test system Digital beam position monitor processor Program control Experimental physics and industrial control system Analog-to-digital converter

Design of RF front end of digital BPM for BEPCII

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Radiation Detection Technology and Methods 2019年第3期3卷 160-167页

作者： yaoyao du Jing Yang Lin Wang Xiyang Huang Yufei Ma Xinger Zhang Huizhou Ma Qiang Ye Yanfeng Sui Shujun Wei Junhui Yue Jianshe Cao Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Key Laboratory of Particle Acceleration Physics and Technology Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China

Purpose In order to update the BPM electronic in BEPCII,a high-performance digital BPM processor is designed,and the RF front-end electronic is the key part in the digital BPM processor *** According to the BEPCII physical parameters andADCunder-sampling theorem,the low-noise and high-dynamicrange RF front-end electronic module is *** article will introduce filter,RF amplifier,isolation,system test,*** and conclusions The experimental results showed that BPM position short-term resolution is better than 100 nm,and long-term resolution is better than 5μ*** is the first domestic BPM processor that runs stably in the storage ring accelerator for a long ***,the study can help us to establish a solid foundation for the next work of BPM electronics development.

关键词： BEPCII Digital BPM RF design Disturbance Isolation

Purification and identification of the activity of natural hemolin

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Purification and identification of the activity of natural h...

华东六省一市生物化学与分子生物学学会2014年学术交流大会暨浙江省第十一届学会会员代表大会

作者： SONGRuyun du yaoyao Bi Zhenle ZHANG Yaozhou Lv Zhengbing SHU Jianhong Institute of Biochemistry Zhejiang Sci-Tech University Tianjin International Joint Academy of Biotechnology and Medicine

Tostudy the function of the hemolin protein,we analysised the Sequences of hemolin,and found the homology of Bombyx mori(domestic silkworm)with those of other specieswas 60.78%.Then,a pET system was used to express hemolin in *** to purify hemolin from silkworm pupa naturally,rapidly and *** Ni2+column purification,we obtain purified fused his-tagged hemolin *** New Zealandrabbits were immunized with the his-tagged hemolin to obtain a polyclonal antibody for hemolin(PcAb).We made an antibody chromatography column by Coupling hemolin PcAb to AminoLink Plus Coupling Resin,and used this chromatography column to separate natural hemolin from baculovirus-infected silkworm *** purity of the protein was 79.213%.Through an antibacterial experiment and qPCR analysis,we determined that the purified hemolin isolated from the antibody chromatography column had antibacterial properties.

关键词： hemolin purification high fusion expression level in vitroantibacterial

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文胸模杯曲面形态特征曲线提取与分析

纺织学报 2016年第11期37卷 103-108页

作者：徐瑶瑶朱俐莎杜磊邹奉元浙江理工大学服装学院浙江杭州310018 浙江理工大学浙江省服装工程技术研究中心浙江杭州310018

为获得控制文胸模杯曲面形态的特征曲线,实现模杯的正向设计,采用三维扫描仪获取模杯的点云数据,用逆向工程软件进行实体模型构建,然后根据模杯角度及特征点构建了26条模杯内外曲面形态曲线。利用各曲线拐点、峰值点、曲率最大点及最小... 详细信息

为获得控制文胸模杯曲面形态的特征曲线,实现模杯的正向设计,采用三维扫描仪获取模杯的点云数据,用逆向工程软件进行实体模型构建,然后根据模杯角度及特征点构建了26条模杯内外曲面形态曲线。利用各曲线拐点、峰值点、曲率最大点及最小点的分布位置一致性,提取能够反映模杯曲面特征信息的内外曲面形态特征曲线5条。结果表明:模杯结构特征曲线上的几何参数分布离散程度更小,较角度特征曲线更能反映不同类型模杯的曲面形态特征。拟合各特征曲线弧长与模杯杯深的函数关系,通过改变形态特征曲线上的几何参数可控制曲面形态结构。

关键词：文胸模杯角度曲线结构曲线离散程度分布位置

基于SBM-DEA模型湖南省碳排放效率时空差异及影响因素分析

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地理科学 2019年第5期39卷 797-806页

作者：王兆峰杜瑶瑶湖南师范大学旅游学院

以中部湖南省为研究区域,利用超效率SBM-DEA模型与Malmquist指数对2010~2016年湖南省14个市(州)碳排放效率和环境效率进行测度和空间差异分析,结果发现:①从时间序列演化特征来看,除长沙市、常德市外,湖南省大部分市(州)的碳排放效率和... 详细信息

以中部湖南省为研究区域,利用超效率SBM-DEA模型与Malmquist指数对2010~2016年湖南省14个市(州)碳排放效率和环境效率进行测度和空间差异分析,结果发现:①从时间序列演化特征来看,除长沙市、常德市外,湖南省大部分市(州)的碳排放效率和环境效率偏低,纯技术效率的贡献较大,技术效率和规模效率发挥不足,部分地区在2010~2016年间的碳排放效率有所提高,但均低于10%的增长水平;②从空间格局分布来看,湖南省14市(州)的效率水平差异显著,表现为碳排放效率由中部地区逐步向边缘地区进行转移和提升,而环境效率的波动性较大,整体呈现出'分散-集聚-分散'的趋势。五大能源区域中湘东地区的效率水平较高,其次为湘北地区,湘南地区与湘西地区表现为空间互补型区域,湘中地区的效率水平提升则相对滞后;③从影响因素的分析来看,二、三产业的作用效果不显著,生态环境、工业产业集聚和对外依存度对碳排放效率具有负向作用,技术进步则表现出积极的正向影响。最后,提出结合现有的政策引导和技术水平发展,充分发挥好各地区经济规模效应,促进生产要素在区域间的快速流动,推动技术进步成为节能减排的主要驱动等建议。

关键词：超效率SBM-DEA模型 Malmquist指数碳排放效率环境效率湖南

高校职务科技成果转化权利配置研究——基于美国常青藤大学的实证研究

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科学学与科学技术管理 2018年第4期39卷 18-34页

作者：郭英远张胜杜垚垚西安交通大学公共政策与管理学院西安710049

高校成果转化权利配置方式无疑是最根本的因素,其中处置权和收益权的配置模式又是权利配置中最关键、最核心的要素。如何科学配置高校职务科技成果转化权利,以提升科技成果转化效率一直是学者们研究的热点问题。首先,从理论角度论述当... 详细信息

高校成果转化权利配置方式无疑是最根本的因素,其中处置权和收益权的配置模式又是权利配置中最关键、最核心的要素。如何科学配置高校职务科技成果转化权利,以提升科技成果转化效率一直是学者们研究的热点问题。首先,从理论角度论述当高校拥有自主处置和收益权之后,其内部应该如何配置科技成果转化权利,以提升成果转化绩效,并据此提出3个研究假设;其次,以美国常春藤大学的科技成果转化权利配置为实证案例,基于对美国大学成果转化权利配置方式的发现来分析并验证3个研究假设的有效性;结果发现,学校委托专业成果转化团队主导处置成果,能降低成果转化中信息、谈判、契约等交易成本,有利于提高成果转化效率;发明人及团队参与成果转化处置,能降低成果转化中信息交易成本,有利于提高成果转化效率;高校在学校、学院(系)、发明人及团队、专业成果转化团队间建立激励兼容的收益共享模式,能以利益为纽带将4个利益相关者连接起来,各司其职,共同致力于提高成果转化效率。

关键词：高校职务科技成果转化权利配置处置权收益权美国常青藤大学