检索结果-南通市图书馆

SYNTHESIS　OF　4－S－（5″－ALKYL－4″－AMINO－1″，2″，4″－TRIAZOLE－3″－YL）－4－DEOXY－4′－DEMETHYL－EPIPODOPHYLLOTOXIN　ANALOGUES

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1995年第5期6卷 361-362页

作者： Kuan Ke LU Fang Min LIU yao zu CHEN(Department of Chemistry, Lanzhou University,Lanzhou,730000) Lanzhou Univ Dept Chem Lanzhou 730000 Peoples R China

Seven title compounds were synthesized by condensation ot 4′-demethylepipodophyllotoxin With 5-alkyl-4-amino -3-mercapto -1,2,4- trizoles in the presence of CF3COOH(TFA).

关键词：

A NOVEL SILACARBOCYANINE DYE

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1995年第1期6卷 17-18页

作者： yao Jun ZHANG Ji Xiang HAO zu Xun ZHANG Department of Chemistry, Northwest University, Xi’an, 710069 NW Univ Xian Dept Chem Xian 710069 Peoples R China

A new type of photographic spectral sensitizer containing silicon-carbon double. bond is reported. The application tests show that the dye has excellent sensitivity in silver iodobromide emulsion and that the sensitivity maximum (S-max) of emulsion sensitized by the dye gives a hypsochromic shift about 70nm as compared with the absorption maximum (lambda (max)) of the dye in methanol. This phenomenon differs entirely from typical photographic spectral sensitizing dye.

关键词：

Improving RSW nugget diameter prediction method:unleashing the power of multi-fidelity neural networks and transfer learning

在线全文

学校读者我要写书评

暂无评论

Advances in Manufacturing 2024年第3期12卷 409-427页

作者： Zhong-Jie Yue Qiu-Ren Chen zu-Guo Bao Li Huang Guo-Bi Tan Ze-Hong Hou Mu-Shi Li Shi-yao Huang Hai-Long Zhao Jing-Yu Kong Jia wang Qing Liu Key Laboratory for Light-weight Materials Nanjing Tech UniversityNanjing210009People’s Republic of China School of Advanced Technology Xi’an Jiaotong-Liverpool UniversitySuzhou215123JiangsuPeople’s Republic of China Material Academy JITRISuzhou215100JiangsuPeople’s Republic of China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai200240People’s Republic of China

This research presents an innovative approach to accurately predict the nugget diameter in resistance spot welding(RSW)by leveraging machine learning and transfer learning ***,low-fidelity(LF)data were obtained through finite element numerical simulation and design of experiments(DOEs)to train the LF machine learning ***,high-fidelity(HF)data were collected from RSW process experiments and used to fine-tune the LF model by transfer learning *** accuracy and generalization performance of the models were thoroughly *** results demonstrated that combining different fidelity datasets and employing transfer learning could significantly improve the prediction accuracy while minimize the costs associated with experimental trials,and provide an effective and valuable method for predicting critical process parameters in RSW.

关键词： Resistance spot welding(RSW) Nugget diameter prediction Multi-fidelity neural networks Transfer learning

High formability Mg-Zn-Gd wire facilitates ACL reconstruction via its swift degradation to accelerate intra-tunnel endochondral ossification

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第1期12卷 295-315页

作者： Xuan He Ye Li Hongwei Miao Jiankun Xu Michael Tim-yun Ong Chenmin wang Lizhen Zheng Jiali wang Le Huang Haiyue zu Zhi yao Jie Mi Bingyang Dai Xu Li Patrick Shu-hang Yung Guangyin Yuan Ling Qin Musculoskeletal Research Laboratory of Department of Orthopaedics&Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory of Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongHong KongChina National Engineering Research Center of Light Alloy Net Forming School of Materials Science&EngineeringShanghai Jiao Tong UniversityShanghaiChina Department of Orthopaedics and Traumatology Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongChina Orthopaedic Department Peking University Third HospitalBeijingChina Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHong KongChina

After reconstructing the anterior cruciate ligament(ACL),unsatisfactory bone tendon interface healing may often induce tunnel enlargement at the early healing *** good biological features and high formability,Magnesium-Zinc-Gadolinium(ZG21)wires are developed to bunch the tendon graft for matching the bone tunnel during ***,tensile strength,degradation,and cytotoxicity of ZG21 wire are *** rabbit model is used for assessing the biological effects of ZG21 wire by Micro-CT,histology,and mechanical *** SEM/EDS,immunochemistry,and in vitro assessments are performed to investigate the underlying *** tests demonstrate the high formability of ZG21 wire as surgical ***-CT shows ZG21 wire degradation accelerates tunnel bone formation,and histologically with earlier and more fibrocartilage regeneration at the healing *** mechanical test shows higher ultimate load in the ZG21 *** SEM/EDS presents ZG21 wire degradation triggered calcium phosphate(Ca-P)*** results demonstrate upregulation of Wnt3a,BMP2,and VEGF at the early phase and TGFβ3 and Type II collagen at the late phase of *** vitro tests also confirmed the Ca-P in the metal extract could elevate the expression of Wnt3a,βcatenin,ocn and opn to stimulate *** vivo tests of clinical samples indicated suturing with ZG21 wire did not weaken the ultimate loading of human tendon *** conclusion,the ZG21 wire is feasible for tendon graft *** degradation products accelerated intra-tunnel endochondral ossification at the early healing stage and therefore enhanced bone-tendon interface healing in ACL reconstruction.

关键词： Magnesium wire ACL reconstruction Magnesium alloy Biomaterials Endochondral ossification

A Facile Synthesis of (-)-5_αH,7β,10_α-Eudesmane-3,1 1-diene

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1996年第12期7卷 1081-1082页

作者： Ning ZOU Dong Liang CHENG Xin Fu PAN yao zu CHEN(Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000) LANZHOU UNIV DEPT CHEMLANZHOU 730000PEOPLES R CHINA

s: The convenient synthesis of (-)-5αH.7β 10α-eudesmane-3. 11-dielle 1 has been achieved in four steps starting from R-(-)-carvone. The key step is the reductive deoxygenation of α,β-unsaturated tosylhydrazone to... 详细信息

关键词： A Facile Synthesis of Eudesmane-3,1 1-diene H,7

Preparation of Aluminum Foam Sandwich by Rolling-bonding/Powder Metallurgy Foaming Technology

在线全文

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2011年第4期26卷 671-674页

作者：祖国胤 School of Materials & Metallurgy Northeastern University

Aluminum foam sandwich was prepared by rolling-bonding/powder metallurgical foaming technology, and the effects of rolling on bond strength of face sheet/powders and powder density were studied. Moreover, the foaming agent, TiH2, was heat treated and a certain amount of Mg was added into powder in an attempt to understand how the stability and uniformity of foam was improved. The experimental results show that the foaming precursors with ideal quality were obtained by rolling-bonding process. When rolling reduction is 67%, the consistency of powders reach to 99.87%. Throughout consideration of the bonding of face sheet/ core layer powders and deformation characteristic of powders, the optimum rolling reduction is 60%-70%. Cracks and drainage during foaming were inhibited by heat treatment of foaming agent TiH2 and the addition of a certain amount of Mg. The optimum heat treatment way of TiH2 is that heat preserving 1 hour at 450 ℃; the amount of adding Mg is 1wt%.

关键词： aluminum foam sandwich rolling bonding foaming relative density stability

Biosorption effects of copper ions on Candida utilis under negative pressure cavitation

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2006年第6期18卷 1254-1259页

作者： zu Yuan-gang ZHAO Xiu-hua HU Mao-sheng REN Yuan XIAO Peng ZHU Lei CAO Yu-jie ZHANG yao Key Laboratory of Forest Plant Ecology Northeast Forestry University Ministry of Education Harbin 150040 China

Under the optimal condition of copper ions adsorption on yeast,we found some different effects among static adsorption, shaking adsorption and negative pressure cavitation adsorption, and the methods of yeast with different pretreatments also affect adsorption of copper ions. At the same time, the change of intercellular pH before and after adsorption of copper with BCECF was studied. The copper distribution was located by using PhenGreen （dipotassium salt and diacetate）, and the surface of yeast was observed by an atomic force microscope. The results showed that negative pressure cavitation can improve bioadsorption capacity of copper ions on yeast. However, the yeasts＇ pretreatment has a higher effect on bioadsorption. It indicates that heavy metal bioadsorption on yeast has much relation with its cellular molecule basis. With the adsorping, the intercellular pH of yeast increased gradually and changed from acidity to alkalescence. These results may suggest that negative pressure cavitation can compel heavy metals to transfer from the cell surface into inside cell and make the surface of yeast coarse.

关键词： negative pressure cavitation Candida utilis biosorption copper ion adsorption mechanism

Analyzing the transient effects of 60Co gamma rays in a CIS by Monte Carlo method

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2019年第7期30卷 100-106页

作者： Yuan-Yuan Xue zu-Jun wang Min-Bo Liu Rui Xu Hao Ning Wen Zhao Bao-Ping He Zhi-Bin yao Jiang-Kun Sheng Wu-Ying Ma Guan-Tao Dong The State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Northwest Institute of Nuclear Technology Xi’an 710613 China School of Materials Science and Engineering Xiangtan University Xiangtan 411105 China

The objective of this work is to analyze the transient effects of ^60Co gamma rays in the CMOS image sensor (CIS) using the Monte Carlo method, based on Geant4. The track, energy spectrum, and angle of produced electrons when gamma rays traversed a silicon or silicon dioxide cube were calculated. A simplified model of a 500 × 500 CIS array was established, and the transient effects of gamma rays in the CIS were simulated. The raw images were captured when the CIS was irradiated by gamma rays. The experimental results were compared with the simulation results. The characteristics of the typical events induced by transient effects were analyzed.

关键词： ^60Co gamma rays Transient effects CMOS image sensor (CIS) Geant4

Comparison of gene expression responses of zebrafish larvae to Vibrio parahaemolyticus infection by static immersion and caudal vein microinjection

在线全文

学校读者我要写书评

暂无评论

Aquaculture and Fisheries 2021年第3期6卷 267-276页

作者： Xinya Guo Ce Ji Xuan Du Jianfeng Ren yao zu Weiming Li Qinghua Zhang Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources Ministry of EducationShanghai Ocean UniversityShanghai201306China International Research Center for Marine Biosciences Ministry of Science and TechnologyShanghai Ocean UniversityShanghai201306China National Pathogen Collection Center for Aquatic Animals Ministry of AgricultureShanghai Ocean UniversityShanghai201306China Department of Fisheries and Wildlife Michigan State UniversityEast LansingMI48824USA

infection model for studying inflammation and the innate immune *** investigated the genes and signaling pathways activated by static immersion and caudal vein microinjection infection using transcriptome profiling and reverse-transcription quantitative PCR(RT-qPCR)to compare the innate immune response in 3 days post-fertilization(dpf)zebrafish larvae infected by Vibrio parahaemolyticus Vp13 *** median lethal dose(LD50)values at 96 h following immersion and microinjection were 3.63×107 CFU/mL and 5.76×102 CFU/nL,*** innate immune response was initiated after 2 h of incubation with the respective LD50 for each infection *** hundred and two genes in the immersion group and 359 genes in the microinjection group were activated and differentially expressed ***-three Gene Ontology(GO)terms and four Kyoto Encyclopedia of Genes and Genomes(KEGG)pathways were significantly enriched in the immersion group,compared with only three GO terms and no KEGG pathways in the microinjection *** genes,tnfb and ccl20a.3,were significantly up-regulated in both *** speculated that immersion infection may affect initial dorsal determination,cytochromes,and fatty acid-binding proteins,as well as inflammation,while microinjection infection may mainly directly affect the immune *** with doses>LD50(1.09×109 CFU/mL and 1.09×103 CFU/nL by immersion and microinjection,respectively)caused more significant up-regulation of il11a,tnfa,tnfb,il1b,ccl34a.4,ccl20a.3,irak3,cxcl18b,and ccl35.1,suggesting that in addition to the classical innate immunity genes tnfa,tnfb,il1b,and il6,the genes il11a,ccl34a.4,ccl20a.3,cxcl18b,and ccl35.1 were also important for defending against Vp13 *** findings highlight the genes involved in the responses of zebrafish to Vp13 infection via different routes and doses,and thus provide the basis for further analyses of immune response signaling pathways.

关键词： Immersion Microinjection Transcriptome Vibrio parahaemolyticus Zebrafish