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Promotion of Cooperation in a Spatial Public Goods Game with Long Range Learning and Mobility

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Chinese Physics Letters 2012年第11期29卷 231-235页

作者： XIAO yao hua Da-Yin Department of Physics Ningbo UniversityNingbo 315211

We studied the effect of population density in a spatial public goods *** found that the effect on the evolution of cooperation is very complex when the strategy learning and mobility of players in a long range are considered in a two-dimensional *** the learning range is larger than the mobility range,the system is driven to enter into a cooperation state for a low population density,because a small local group is beneficial to sustain a high level of *** population density increases to a moderate range,the mobility of players from a domain invaded by defectors supports the evolution stability of *** the mobility range is larger than the learning range,a formation of compact domains of cooperators promotes cooperation as the population density becomes high.

关键词： cooperation operators learning

Two new ursane-type nortriterpenes from Lonicera macranthoides and their iNOS-inhibitory activities

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Chinese Journal of Natural Medicines 2019年第1期17卷 27-32页

作者： MEI yu-Dan ZHANG Nan ZHANG Wei-Yang TANG Jin-Shan ZHOU hua yu Yang yao Xin-Sheng Institute of Traditional Chinese Medicine&Natural Products College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs ResearchJinan University XiangXue Academician workstation Xiangxue Pharmaceutical Co.Ltd. College of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Faculty of Chinese Medicine Macao University of Science and Technology and State Key Laboratory of Quality Research in Chinese Medicine(Macao University of Science and Technology)

The flower buds of Lonicera macranthoides(Shan Yin-hua), represent an important traditional Chinese medicine and food ingredient. A phytochemical investigation of the 70% EtOH extract of the flower buds of L. macranthoides resulted in the isolation of 12 triterpenoids(1-12), including two new ursane-type nortriterpenes, 2α, 24-dihydroxy-23-nor-ursolic acid(1) and 2α, 4α-dihydroxy-23-nor-ursolic acid(2). Their structures were established by multiple spectroscopic methods and comparison with literature data. All isolated compounds were evaluated for their anti-inflammatory effects in LPS-activated RAW264.7 cells. Compounds 1 and 2 exhibited inhibitory effects on iNOS at the concentration of 30 μmol·L^(-1).

关键词： Lonicerae Flos Lonicera macranthoides Ursane-type nortriterpenes Anti-inflammation iNOS

Dissimilatory reduction of Fe^III (EDTA) with microorganisms in the system of nitric oxide removal from the flue gas by metal chelate absorption

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Journal of Environmental Sciences 2004年第3期16卷 428-430页

作者： MABi-yao LIWei JINGGuo-hua SHIyao InstituteofEnvironmentalEngineering ZhejiangUniversityHangzhou310027China

In the system of nitric oxide removal from the flue gas by metal chelate absorption, it is an obstacle that ferrous absorbents are easily oxidized by oxygen in the flue gas to ferric counterparts, which are not capable of binding NO. By adding iron metal or electrochemical method, Fe III (EDTA) can be reduced to Fe II (EDTA). However, there are various drawbacks associated with these techniques. The dissimilatory reduction of Fe III (EDTA) with microorganisms in the system of nitric oxide removal by metal chelate absorption was investigated. Ammonium salt instead of nitrate was used as the nitrogen source, as nitrates inhibited the reduction of Fe III due to the competition between the two electron acceptors. Supplemental glucose and lactate stimulated the formation of Fe II more than ethanol as the carbon sources. The microorganisms cultured at 50℃ were not very sensitive to the other experimental temperature, the reduction percentage of Fe III varied little with the temperature range of 30—50℃. Concentrated Na 2CO 3 solution was added to adjust the solution pH to an optimal pH range of 6—7 The overall results revealed that the dissimilatory ferric reducing microorganisms present in the mix culture are probably neutrophilic, moderately thermophilic Fe III reducers.

关键词： dissimilatory ferric reducing microorganisms Fe III (EDTA) microbial reduction mix culture

Scattering Theory for the Defocusing Fourth Order NLS with Potentials

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Acta Mathematica Sinica,English Series 2018年第4期34卷 773-786页

作者： Hong Liang FENG hua WANG Xiao hua yao School of Mathematics and Statistics Central China Normal University Wuhan 430079 P. R. China School of Mathematics and Statistics and Hubei Province Key Laboratory of Mathematical Physics Central China Normal University Wuhan 430079 P. R. China

Based on the endpoint Strichartz estimates for the fourth order SchrSdinger equation with potentials for n ≥ 5 by [Feng, H., Softer, A., yao, X.： Decay estimates and Strichartz estimates of the fourth-order Schr6dinger operator. J. Funct. Anal., 274, 605-658 （2018）], in this paper, the authors further derive Strichartz type estimates with gain of derivatives similar to the one in [Pausader, B.： The cubic fourth-order Schr6dinger equation. J. Funct. Anal., 256, 2473-2517 （2009）]. As their applications, we combine the classical Morawetz estimate and the interaction Morawetz estimate to establish scattering theory in the energy space for the defocusing fourth order NLS with potentials and pure power nonlinearity 1 ＋ 8/n〈 p 〈 1 ＋ 8/n-4 in dimensions n ≥ 7. n

关键词： Fourth order NLS potential morawetz estimate scattering

Commutativity Conditions for Rings and Generalized 2-CN Rings

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Algebra Colloquium 2021年第1期28卷 51-62页

作者： hua yao Jianhua Sun Junchao Wei School of Mathematics and Statistics Huanghuai UniversityZhumadianHenan 463000China School of Mathematical Sciences Yangzhou UniversityYangzhouJiangsu 225002China

Firstly,the commutativity of rings is investigated in this *** R be a ring with *** we obtain the following commutativity conditions:(1)if for each x∈R\N(R)and each y∈R,(xy)^(k)=x^(k)y^(k)for k=m,m+1,n,n+1,where m and n are relatively prime positive integers,then R is commutative;(2)if for each x∈R\J(R)and each y∈R,(xy)^(k)=y^(k)x^(k)for k=m,m+1,m+2,where m is a positive integer,then R is ***,generalized 2-CN rings,a kind of ring being commutative to some extent,are *** relations between generalized 2-CN rings and other kinds of rings,such as reduced rings,regular rings,2-good rings,and weakly Abel rings,are presented.

关键词： commutativity conditions generalized 2-CN rings regular rings 2-good rings weakly Abel rings

Projectively flat arctangent Finsler metric

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第12期7卷 2097-2103页

作者： yu yao-yong Department of Mathematics Zhejiang University Hangzhou 310028 China

In this work, we study a class of special Finsler metrics F called arctangent Finsler metric, which is a special （α, β）-metric, where a is a Riemannian metric and β is a 1-form, We obtain a sufficient and necessary condition that F is locally projectively fiat if and only if α and β satisfy two special equations. Furthermore we give the non-trivial solutions for F to be locally projectively fiat. Moreover, we prove that such projectively fiat Finsler metrics with constant flag curvature must be locally Minkowskian.

关键词： Arctangent Finsler metric Projectively flat (α,β)-metric Flag curvature

Inflammasomes as therapeutic targets in human diseases

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Signal Transduction and Targeted Therapy 2021年第8期6卷 2334-2347页

作者： Yangxin Li Hui huang Bin Liu yu Zhang Xiangbin Pan Xi-Yong yu Zhenya Shen yao-hua Song Institute for Cardiovascular Science and Department of Cardiovascular Surgery First Affiliated Hospital and Medical College of Soochow UniversityCollaborative Innovation Center of HematologySoochow UniversitySuzhouJiangsuP.R.China Cardiovascular Department The Eighth Affiliated HospitalSun Yat-sen UniversityShenzhenGuangdongP.R.China Department of Cardiology The Second Hospital of Jilin UniversityChangchunJilinP.R.China Department of Cardiac Surgery Fuwai HospitalBeijingP.R.China Key Laboratory of Molecular Target&Clinical Pharmacology and the State Key Laboratory of Respiratory Disease Guangzhou Medical UniversityGuangzhouGuangdongP.R.China Cyrus Tang Hematology Center Collaborative Innovation Center of HematologySoochow UniversityNational Clinical Research Center for Hematologic Diseasesthe First Affiliated Hospital of Soochow UniversityState Key Laboratory of Radiation Medicine and ProtectionSoochow UniversitySuzhouChina

Inflammasomes are protein complexes of the innate immune system that initiate inflammation in response to either exogenous pathogens or endogenous danger *** multiprotein complexes are composed of three parts:a sensor protein,an adaptor,and *** of the inflammasome leads to the activation of caspase-1,which cleaves pro-inflammatory cytokines such as IL-ip and IL-18,leading to *** of the inflammasome not only provide protection against infectious pathogens,but also mediate control over sterile *** inflammasome signaling has been implicated in the development of cardiovascular and metabolic diseases,cancer,and neurodegenerative ***,we review the role of the inflammasome as a double-edged sword in various diseases,and the outcomes can be either good or bad depending on the disease,as well as the genetic *** highlight inflammasome memory and the two-shot activation *** also propose the M-and N-type inflammation model,and discuss how the inflammasome pathway may be targeted for the development of novel therapy.

关键词： diseases inflammation endogenous

Constraint-induced movement therapy enhances AMPA receptor-dependent synaptic plasticity in the ipsilateral hemisphere following ischemic stroke

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Neural Regeneration Research 2021年第2期16卷 319-324页

作者： Jian Hu Pei-Le Liu Yan hua Bei-yao Gao yu-yuan Wang yu-Long Bai Chan Chen Department of Rehabilitation Medicine Huashan HospitalFudan UniversityShanghaiChina

Constraint-induced movement therapy(CIMT)can promote the recovery of motor function in injured upper limbs following stroke,which may be associated with upregulation ofα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor(AMPAR)at synapses in the ipsilateral sensorimotor cortex in our previous ***,AMPAR distribution is tightly regulated,and only AMPARs on the postsynaptic membrane can mediate synaptic *** speculated that synaptic remodeling induced by movement-associated synaptic activity can promote functional recovery from *** test this hypothesis,we compared AMPAR expression on the postsynaptic membrane surface in a rat model of ischemic stroke induced by middle cerebral artery occlusion(MCAO)with versus without CIMT,which consisted of daily running wheel training for 2 weeks starting on day 7 after *** results showed that CIMT increased the number of glutamate receptor(Glu R)2-containing functional synapses in the ipsilateral sensorimotor cortex,and reduced non-Glu R2 AMPARs in the ipsilateral sensorimotor cortex and hippocampal CA3 *** addition,CIMT enhanced AMPAR expression on the surface of post-synaptic membrane in the ipsilateral sensorimotor cortex and ***,CIMT promotes the recovery of motor function of injured upper limbs following stroke by enhancing AMPAR-mediated synaptic transmission in the ischemic *** findings provide supporting evidence for the clinical value of CIMT for restoring limb movement in stroke *** experimental procedures and protocols were approved by the Department of Laboratory Animal Science of Fudan University,China(approval No.201802173 S)on March 3,2018.

关键词： brain experiment injury plasticity regeneration repair stroke synapse

Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

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Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-Hui Jiang Hui-Li Kang Yi Jiang hua-Wei Zhang Xiao-Mei Song yu-Ze Li Wen-Li huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC