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Real-time in vivo distal margin selection using confocal laser endomicroscopy in transanal total mesorectal excision for rectal cancer

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World Journal of Gastrointestinal Surgery 2022年第12期14卷 1375-1386页

作者： Jie Tan Hong-Li Ji yao-wen hu Zhi-Ming Li Bao-Xiong Zhuang Hai-Jun Deng Ya-Nan Wang Ji-XiangZheng Wei Jiang Jun Yan Department of General Surgery Nanfang HospitalGuangzhou 510515Guangdong ProvinceChina Department of General Surgery Southern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor Nanfang HospitalGuangzhou 510515Guangdong ProvinceChina

BACKGROUND Transanal total mesorectal excision(TaTME)allows patients with ultralow rectal cancer to be treated with sphincter-saving ***,accurate delineation of the distal resection margin(DRM),which is essential to achieve R0 resection for low rectal cancer in TaTME,is technically *** To assess the feasibility of optical biopsy using probe-based confocal laser endomicroscopy(pCLE)to select the DRM during TaTME for low rectal *** A total of 43 consecutive patients who were diagnosed with low rectal cancer and scheduled for TaTME were prospectively enrolled from January 2019 to January *** was used to determine the distal edge of the tumor as well as the DRM during *** final pathological report was used as the gold *** diagnostic accuracy of pCLE examination was *** A total of 86 pCLE videos of 43 patients were included in the *** sensitivity,specificity and accuracy of real-time pCLE examination were 90.00%[95%confidence interval(CI):76.34%-97.21%],86.96%(95%CI:73.74%-95.06%)and 88.37%(95%CI:79.65%-94.28%),*** accuracy of blinded pCLE reinterpretation was 86.05%(95%CI:76.89%-92.58%).Furthermore,our results show satisfactory interobserver agreement(κ=0.767,standard error=0.069)for the detection of cancer tissue by *** were no positive DRMs(≤1 mm)in this *** median DRM was 7 mm[interquartile range(IQR)=5-10 mm].The median Wexner score was 5(IQR=3-6)at 6 mo after stoma *** Real-time in vivo pCLE examination is feasible and safe for selecting the DRM during TaTME for low rectal cancer(clinical trial registration number:NCT04016948).

关键词： Transanal total mesorectal excision Probe-based confocal laser endomicroscopy Optical biopsy Distal resection margin Low rectal cancer

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Photo‑Energized MoS_(2)/CNT Cathode for High‑Performance Li–CO_(2)Batteries in a Wide‑Temperature Range

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Nano-Micro Letters 2025年第1期17卷 160-175页

作者： Tingsong hu wenyi Lian Kang hu Qiuju Li Xueliang Cui Tengyu yao Laifa Shen Jiangsu Key Laboratory of Materials and Technologies for Energy Storage College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Li–CO_(2) batteries are considered promising energy storage systems in extreme environments such as Mars;however,severe performance degradation will occur at a subzero temperature owning to the sluggish reaction ***,a photo-energized strategy adopting sustainable solar energy in wide working temperature range Li–CO_(2) battery was achieved with a binder-free MoS_(2)/carbon nanotube(CNT)photo-electrode as *** unique layered structure and excellent photoelectric properties of MoS_(2) facilitate the abundant generation and rapid transfer of photo-excited carriers,which accelerate the CO_(2) reduction and Li_(2)CO_(3) decomposition upon *** illuminated battery at room temperature exhibited high discharge voltage of 2.95 V and mitigated charge voltage of 3.27 V,attaining superior energy efficiency of 90.2%and excellent cycling stability of over 120 *** at an extremely low temperature of−30℃,the battery with same electrolyte can still deliver a small polarization of 0.45 V by the photoelectric and photothermal synergistic mechanism of MoS_(2)/CNT *** work demonstrates the promising potential of the photo-energized wide working temperature range Li–CO_(2) battery in addressing the obstacle of charge overpotential and energy efficiency.

关键词： Li-CO_(2)batteries Photo-energized Wide operation-temperature Kinetics MoS_(2)

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Boosting Oxygen Evolution Reaction Performance on NiFe‑Based Catalysts Through d‑Orbital Hybridization

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Nano-Micro Letters 2025年第1期17卷 281-292页

作者： Xing Wang Wei Pi Sheng hu Haifeng Bao Na yao Wei Luo State Key Laboratory of New Textile Materials and Advanced Processing Technology Key Laboratory of New Textile Materials and Applications of Hubei ProvinceSchool of Materials Science and EngineeringWuhan Textile UniversityWuhan 430200People’s Republic of China College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072People’s Republic of China

Anion-exchange membrane water electrolyzers(AEMWEs)for green hydrogen production have received intensive attention due to their feasibility of using earth-abundant NiFe-based *** introducing a third metal into NiFe-based catalysts to construct asymmetrical M-NiFe units,the d-orbital and electronic structures can be adjusted,which is an important strategy to achieve sufficient oxygen evolution reaction(OER)performance in ***,the ternary NiFeM(M:La,Mo)catalysts featured with distinct M-NiFe units and varying d-orbitals are reported in this *** and theoretical calculation results reveal that the doping of La leads to optimized hybridization between d orbital in NiFeM and 2p in oxygen,resulting in enhanced adsorption strength of oxygen intermediates,and reduced rate-determining step energy barrier,which is responsible for the enhanced OER *** critically,the obtained NiFeLa catalyst only requires 1.58 V to reach 1 A cm^(−2) in an anion exchange membrane electrolyzer and demonstrates excellent long-term stability of up to 600 h.

关键词： NiFe-based catalysts d-orbital coupling Oxygen evolution reaction Anion exchange membrane electrolyzer

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AIDS合并颜面部播散性粟粒性狼疮1例

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中国皮肤性病学杂志 2008年第12期22卷 740-741页

作者：朱平姚文虎池云东南大学医学院附属南京第二医院感染科江苏南京210003

报告1例AIDS合并颜面部播散性粟粒样狼疮(LMDF)。患者间断性发热3个月,CD4水平低下,曾使用过多种抗生素和皮质激素,在疾病过程中出现颜面部播散性粟粒样狼疮,且经病理组织学确诊。提示免疫功能低下可能是罹患LMDF的一个原因。

关键词： AIDS 播散性粟粒样狼疮

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法国半总统制理论探源

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政法论丛 2008年第5期 93-95页

作者：姚文虎中国人民大学法学院北京100872

半总统制的理论源于法国学者的论述。法国半总统制是对分权制衡理论与公民投票理论的运用和发展。它不但在稳定法国政局方面发挥了重要作用,而且对其他国家的政治体制也产生了一定的影响。

关键词：半总统制分权制衡公民投票

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关于企业办公室管理的相关探讨

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价值工程 2015年第4期34卷 196-197页

作者：姚文虎铜陵有色铜山矿业公司池州247100

新时期,企业的办公室管理工作的职能与责任发生了很大的变化,如何针对于现有办公室管理工作中的不足进行改进,创新办公室管理工作形式,是提高办公室工作效率与质量的关键。本文对于新时期办公室的工作职能进行了分析,并且对既存的不足... 详细信息

新时期,企业的办公室管理工作的职能与责任发生了很大的变化,如何针对于现有办公室管理工作中的不足进行改进,创新办公室管理工作形式,是提高办公室工作效率与质量的关键。本文对于新时期办公室的工作职能进行了分析,并且对既存的不足进行了探讨,最终提出了相应的实施对策。

关键词：企业办公室管理服务规范发展

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Wave effect of gravitational waves intersected with a microlens field Ⅱ:An adaptive hierarchical tree algorithm and population study

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 241-254页

作者： Xikai Shan Guoliang Li Xuechun Chen wen Zhao Bin hu Shude Mao Department of Astronomy Tsinghua University Purple Mountain Observatory Chinese Academy of Sciences Institute for Frontier in Astronomy and Astrophysics Beijing Normal University School of Physics and Astronomy Beijing Normal University School of Astronomy and Space Science University of Science and Technology of China CAS Key Laboratory for Researches in Galaxies and Cosmology Department of Astronomy University of Science and Technology of ChinaChinese Academy of Sciences

The gravitational lensing wave effect generated by a microlensing field embedded in a lens galaxy is an inevitable phenomenon in strong lensed gravitational waves （SLGWs）.This effect presents both challenges and opportunities for the detection and application of ***,investigating this wave effect requires computing a complete diffraction integral over each microlens in the *** is extremely time-consuming due to the large number of microlenses （10～3-10～6）.Therefore,simply adding all the microlenses is ***,the complexity of the time delay surface makes the lens plane resolution a crucial factor in controlling numerical *** this paper,we propose a trapezoid approximation-based adaptive hierarchical tree algorithm to meet the challenges of calculation speed and *** find that this algorithm accelerates the calculation by four orders of magnitude compared to the simple adding method and is one order of magnitude faster than the fixed hierarchical tree algorithm proposed for electromagnetic *** importantly,our algorithm ensures controllable numerical errors,increasing confidence in the *** with our previous work （***.66,239511,2023）,this paper addresses all numerical issues,including integral convergence,precision,and computational time1).Finally,we conducted a population study on the microlensing wave effect of SLGWs using this algorithm and found that the microlensing wave effect cannot be ignored,especially for Type II SLGWs （from saddle position of the time delay surface） due to their intrinsic geometric structures and their typical intersection with a denser microlensing ***,more than 33%（11%） of SLGWs have a mismatch larger than 1%（3%） compared to the unlensed ***,we found that the mismatch between signal pairs in a doubly imaged GW is generally larger than 10-3,and 61%（25%） of signal pairs have a mismatch larger than 1%（3%）.Therefo

关键词： gravitational lensing diffractional integral algorithm gravitational wave

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帕罗西汀治疗HIV感染者和AIDS患者伴发的抑郁症临床观察

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中国生化药物杂志 2009年第5期30卷 338-339页

作者：朱云鸿姚文虎池云东南大学附属南京第二医院感染科江苏南京210003

目的研究帕罗西汀对HIV/AIDS患者伴发的抑郁症疗效。方法评价我院2007年1月至2009年6月期间34例门诊和住院HIV/AIDS并抑郁症患者采用帕罗西汀治疗的疗效。结果完成6周治疗,HAMD和HAMA评分明显降低。结论帕罗西汀对HIV/AIDS并发的抑郁症... 详细信息

目的研究帕罗西汀对HIV/AIDS患者伴发的抑郁症疗效。方法评价我院2007年1月至2009年6月期间34例门诊和住院HIV/AIDS并抑郁症患者采用帕罗西汀治疗的疗效。结果完成6周治疗,HAMD和HAMA评分明显降低。结论帕罗西汀对HIV/AIDS并发的抑郁症疗效肯定。

关键词：帕罗西汀 HIV/AIDS 抑郁症

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Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan hu Yue Li hua Zhang Lian-Lian Wang wen-wen Liu Xin Yang Ming-Zhao Xiao Hao-Ling Zhang Juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further *** levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC *** professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

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AIDS患者外周血淋巴细胞表面CCR5、CXCR4表达情况分析

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中华男科学杂志 2005年第8期11卷 574-576,580页

作者：赵伟吴引伟刘伟姚文虎赵红东南大学医学院附属南京第二医院江苏南京210003

目的:研究人免疫缺陷病毒/获得性免疫缺陷综合征(H IV/AIDS)患者淋巴细胞表面第二受体CCR5、CX-CR4的表达情况,分析其临床意义。方法:收集30例H IV/AIDS患者及16例健康对照的抗凝全血,用流式细胞仪检测第二受体CCR5、CXCR4的表达情况,... 详细信息

目的:研究人免疫缺陷病毒/获得性免疫缺陷综合征(H IV/AIDS)患者淋巴细胞表面第二受体CCR5、CX-CR4的表达情况,分析其临床意义。方法:收集30例H IV/AIDS患者及16例健康对照的抗凝全血,用流式细胞仪检测第二受体CCR5、CXCR4的表达情况,并分析第二受体表达与CD4+T细胞绝对值及T细胞活化(HLA-DR+CD38+)的相关性。结果:AIDS组CD8+T细胞表面CCR5表达明显低于健康对照(P<0.01);AIDS组CD4+T、CD8+T细胞表面CXCR4表达低于健康对照(P<0.01)。H IV/AIDS患者CD4+T、CD8+T细胞表面CCR5、CXCR4的表达与T细胞活化(HLA-DR+)水平明显正相关(P<0.05)。结论:H IV感染者第二受体CCR5、CXCR4的表达与机体对H IV的免疫反应及疾病进展密切相关。

关键词：人免疫缺陷病毒获得性免疫缺陷综合征第二受体CCR5 CXCR4

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