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Hemorrhagic blisters in fulminant Aeromonas hydrophila bacteremia: Case report and literature review

Asian Pacific Journal of Tropical Medicine 2019年第2期12卷 91-94页

作者： yao-tien chang Sung-Yuan Hu Che-An Tsai Department of Emergency Medicine Taichung Veterans General Hospital Department of Nursing College of Health National Taichung University of Science and Technology School of Medicine Chung Shan Medical University Institute of Medicine Chung Shan Medical University Department of Nursing College of Nursing Central Taiwan University of Science and Technology Division of Infectious Disease Department of Internal Medicine Taichung Veterans General Hospital

The Aeromonas species, belonging to the family Aeromonadaceae, are opportunistic pathogens found in humans with an incidence rate of 76 cases per million inhabitants in Southern *** incidence of Aeromonas septicemia is relatively low, accounting for less than 15% of *** diagnosed with Aeromonas hydrophila bacteremia who were presented with skin blisters and septic shock have been reported to have a mortality rate of 100%.Aeromonas infection must be considered in the differential diagnosis of gangrene-like tissue damage or skin lesions in patients with end-stage renal disease, due to the potential sources of infections.A 49-year-old Taiwan Residents diabetic woman with end-stage renal disease had underwent regular *** was referred to our hospital due to a one-day course of fever, dyspnea, hypotension, and fulminant hemorrhagic blisters covering her whole body.A physical examination uncovered multiple hemorrhagic blisters, along with a ruptured blister over the lower left *** tests revealed an elevation of liver enzymes, impaired renal function, lactatemia, and high anion-gap metabolic *** of both blood and hemorrhagic blister fluid grew Aeromonas ***, she experienced persistent shock despite aggressive intravenous fluid, empiric antibiotics, and inotropic agents with norepinephrine and *** diagnosis and prompt management using intravenous fluids, antibiotics and surgical debridement is recommended in order to improve a patient's survival rate.

关键词： Aeromonas hydrophila Bacteremia End-stage renal disease Hemorrhagic blister

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Prostatic abscess of Klebsiella pneumoniae complicating septic pulmonary emboli and meningitis: A case report and brief review

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Asian Pacific Journal of Tropical Medicine 2017年第1期10卷 98-100页

作者： Jai-Wen Liu Tzu-Chieh Lin yao-tien chang Che-An Tsai Sung-Yuan Hu Department of Emergency Medicine Chung Shan Medical University Hospital School of Medicine Chung Shan Medical University Department of Emergency Medicine Taichung Veterans General Hospital Department of Nursing College of HealthNational Taichung University of Science and Technology Department of Nursing College of NursingCentral Taiwan University of Science and Technology Department of Public Health College of Public HealthChina Medical University Division of Infectious Disease Department of Internal MedicineTaichung Veterans General Hospital Institute of Medicine Chung Shan Medical University

Prostatic abscess is a rare entity with an incidence of 0.5% to 2.5% in all prostate diseases and usually occurs in the 5th and 6th decades of life with immunocompromised status,Prostatic abscess might be a process of evolution from acute prostatitis,Klebsiella pneumoniae is the leading microorganism in the diabetic patients of prostatic abscess in Taiwan,A 60-year-old diabetic man,with a one-week history of acute bacterial prostatitis was reported in this study,presenting to the emergency department with sudden altered mental status,The abdominal computed tomographic scan demonstrated lobulated prostatic abscess and multiple septic pulmonary emboli with lung abscesses,Analysis of cerebrospinal fluid showed white blood cells of 10 771 counts/mm3 with segmented neutrophils of 99%,Cultures of blood,cerebrospinal fluid and sputum yielded Klebsiella pneumoniae,We concluded that computed tomographic scan can make a definite diagnosis of prostatic abscess associated with complications and management with empiric antibiotics and adequate drainage is suggested.

关键词： Klebsiella pneumoniae Lung abscess Meningitis Prostatic abscess Septic emboli

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Vector field path following for a micro flapping-wing robot

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Science China(Information Sciences) 2024年第6期67卷 442-444页

作者： Haifeng HUANG Yingte LIU Tao NIU chang WANG yao ZOU Wei HE School of Intelligence Science and Technology University of Science and Technology Beijing Institute of Artificial Intelligence University of Science and Technology Beijing Key Laboratory of Intelligent Bionic Unmanned Systems Ministry of EducationUniversity of Science and Technology Beijing

Flapping-wing robots mimic the flight patterns of natural flying creatures,granting them natural *** hold promising applications in the military reconnaissance,urban surveillance,and various other fields[1–3].However,the current limitations in size often restrict the suitability of existing bird-like flapping-wing robots,

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A systematic evaluation of computational methods for predicting translated non-canonical ORFs from ribosome profiling data

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Journal of Genetics and Genomics 2024年第1期51卷 105-108页

作者： Tianyu Lei Yue chang Chao yao Hong Zhang College of Ecology Lanzhou UniversityLanzhouGansu 730000China Cuiying Honors College Lanzhou UniversityLanzhouGansu 730000China

Ribosome profiling(Ribo-Seg)enables genome-wide survey of translational activities at nucleotide resolution by enriching and sequencing ribosome-protected fragments(RPFs)in the cell(Ingolia et al.,2009).Based on the characteristic distribution of RPFs in Ribo-Seq,such as enrichment in open reading frames(ORFs)and three-nucleotide periodicity,many computational methods have been developed to detect translated ORFs from Ribo-Seq data(Wang et al.,2020a).

关键词： translated enable canonical

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Nanodiamond/Ti_(3)C_(2) MXene-coated quartz crystal microbalance humidity sensor with high sensitivity and high quality factor

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Rare Metals 2024年第6期43卷 2719-2729页

作者： yao yao Qiao Chen Yan-Qi Li Xian-He Huang Wei-Wei Ling Zhe-MiaoXie Jia-QiWang chang-Ming Chen College of Communication Engineering Chengdu University of Information TechnologyChengdu 610225China School of Automation Chongqing University of Posts and TelecommunicationsChongqing 400065China School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Advanced Micro-/Nano-Devices Lab Department of Systems Design EngineeringUniversity of WaterlooWaterlooON N2L 3GlCanada

To address the challenge of achieving both high sensitivity and a high quality factor in quartz crystal microbalance(QCM)humidity sensors,a nanodiamond(ND)/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was *** material characteristics of ND,Ti_(3)C_(2)MXene,and ND/Ti_(3)C_(2)MXene composite were analyzed by transmission electron microscopy(TEM)and Fourier transform infrared(FTIR)*** experimental results demonstrated that the hydrophilic ND nanoparticles coated on Ti_(3)C_(2) MXene nanosheet prevented the self-stacking of Ti_(3)C_(2)MXene and enhanced the sensitivity of Ti_(3)C_(2) MXene-based QCM humidity ***,the high mechanical modulus of Ti_(3)C_(2) MXene material helped ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor to achieve a high quality factor(>20,000).ND/Ti_(3)C_(2)MXene compositecoated QCM humidity sensor exhibited a sensitivity of 82.45 Hz/%RH,a humidity hysteresis of 1.1%RH,fast response/recovery times,acceptable repeatability,and good stability from 11.3%RH to 97.3%*** response mechanism of ND/Ti_(3)C_(2) MXene composite-coated QCM humidity sensor was analyzed in combination with a bi-exponential kinetic adsorption ***,the potential application of ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was demonstrated through its frequency response to wooden blocks with different moisture contents.

关键词： Humidity sensor Quartz crystal microbalance Nanodiamond Ti_(3)C_(2)MXene High quality factor

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Unveiling Organic Electrode Materials in Aqueous Zinc-Ion Batteries:From Structural Design to Electrochemical Performance

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Nano-Micro Letters 2024年第10期16卷 47-81页

作者： Dujuan Li Yuxuan Guo Chenxing Zhang Xianhe Chen Weisheng Zhang Shilin Mei chang-Jiang yao State Key Laboratory of Explosion Science and Safety Protection School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing 100081People's Republic of China

Aqueous zinc-ion batteries(AZIBs)are one of the most compelling alternatives of lithium-ion batteries due to their inherent safety and economics *** response to the growing demand for green and sustainable energy storage solutions,organic electrodes with the scalability from inexpensive starting materials and potential for biodegradation after use have become a prominent choice for *** gratifying progresses of organic molecules with electrochemical performance in AZIBs,the research is still in infancy and hampered by certain issues due to the underlying complex *** for designing organic electrode materials for AZIBs with high specific capacity and long cycling life are discussed in detail in this ***,we put emphasis on the unique electrochemistry of different redox-active structures to provide in-depth understanding of their working *** addition,we highlight the importance of molecular size/dimension regarding their profound impact on electrochemical ***,challenges and perspectives are discussed from the developing point of view for future *** hope to provide a valuable evaluation on organic electrode materials for AZIBs in our context and give inspiration for the rational design of high-performance AZIBs.

关键词： Aqueous zinc-ion batteries Organic electrodes Functional groups Molecular size/geometry Electrochemical performances

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Ultraconformable Integrated Wireless Charging Micro-Supercapacitor Skin

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Nano-Micro Letters 2024年第7期16卷 46-58页

作者： chang Gao Qing You Jiancheng Huang Jingye Sun Xuan yao Mingqiang Zhu Yang Zhao Tao Deng School of Electronic and Information Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China School of Microelectronics Tianjin UniversityTianjin 300072People’s Republic of China Key Laboratory of Cluster Science Ministry of Education of China Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion MaterialsSchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing 100081People’s Republic of China

Conformable and wire-less charging energy storage devices play important roles in enabling the fast development of wearable,non-contact soft ***,current wire-less charging power sources are still restricted by limited flexural angles and fragile connection of components,resulting in the failure expression of performance and constraining their fur-ther applications in health monitoring wearables and moveable artificial ***,we present an ultracompatible skin-like integrated wireless charging micro-supercapacitor,which building blocks(including electrolyte,electrode and substrate)are all evaporated by liquid *** to the infiltration and permeation of the liquid,each part of the integrated device attached firmly with each other,forming a compact and all-in-one *** addition,benefitting from the controllable volume of electrode solution precursor,the electrode thickness is easily regulated varying from 11.7 to 112.5μ*** prepared thin IWC-MSC skin can fit well with curving human body,and could be wireless charged to store electricity into high capacitive micro-supercapacitors(11.39 F cm-3)of the integrated *** believe this work will shed light on the construction of skin-attachable electronics and irregular sensing microrobots.

关键词： Micro-supercapacitor Electronic skin Supercapacitor skin Wireless charging energy storage device

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Mold breakout prediction based on computer vision and machine learning

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Journal of Iron and Steel Research International 2024年第8期31卷 1947-1959页

作者： Yan-yu Wang Qi-can Wang Yong-chang Zhang Yong-hui Cheng Man yao Xu-dong Wang School of Materials Science and Engineering Dalian University of TechnologyDalian 116024LiaoningChina Key Laboratory of Solidification Control and Digital Preparation Technology Dalian University of TechnologyDalian 116024LiaoningChina

Breakout is the most serious production accident in continuous casting and must be detected and predicted by stable and reliable *** sticking region,which forms on the local copper plate and expanded into a"V"shape,is the typical precursor of ***,computer vision technology was exploited to visualize the temperature change rate of the copper plate based on the temperature signals from thermocouples;then,the static and dynamic features of the abnormal sticking region were ***,logistic regression and Adaboost models were used to study and identify these features,resulting in the development of a mold breakout prediction model based on computer vision and machine *** test results demonstrate that the proposed model can effectively distinguish anomalous temperature patterns and considerably reduce false alarms without any missing *** a result,the proposed method could offer valuable insights into the realm of abnormality detection and prediction during continuous casting process.

关键词： Abnormality detection Image processing Adaboost Logistic regression Continuous casting

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Regulation of the quantum barrier and carrier transport toward high-efficiency quasi-2D Dion-Jacobson tin perovskite solar cells

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Journal of Energy Chemistry 2024年第8期95卷 200-207,I0005页

作者： Huanhuan yao chang Shi Tai Wu Shurong Wang Mingyu Yin Liming Ding Yong Hua Feng Hao School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731SichuanChina College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871China Yunnan Key Laboratory for Micro/Nano Materials&Technology School of Materials and EnergyYunnan UniversityKunming 650091YunnanChina Center for Excellence in Nanoscience(CAS) Key Laboratory of Nanosystem and Hierarchical Fabrication(CAS)National Center for Nanoscience and TechnologyBeijing 100190China

Quasi-2D Dion-Jacobson(DJ)tin halide perovskite has attracted much attention due to its elimination of Van der Waals gap and enhanced environmental ***,the bulky organic spacers usually form a natural quantum well structure,which brings a large quantum barrier and poor film quality,further limiting the carrier transport and device ***,we designed three organic spacers with different chain lengths(ethylenediamine(EDA),1,3-propanediamine(PDA),and 1,4-butanediamine(BDA))to investigate the quantum barrier *** and experimental characterizations indicate that EDA with short chain can reduce the lattice distortion and dielectric confinement effect,which is beneficial to the effective dissociation of excitons and the inhibition of trap-free non-radiative *** addition,EDA cation shows strong interaction with the inorganic octahedron,realizing large aggregates in precursor solution and high-quality films with improved structural ***,femtosecond transient absorption proves that EDA cations can also weaken the formation of small n-phases with large quantum barrier to achieve effective carrier transport between different ***,the quasi-2D DJ(EDA)FA_(9)Sn_(10)I_(31)solar cells achieves a 7.07%power conversion efficiency with good environment ***,this work sheds light on the regulation of the quantum barrier and carrier transport through the chain length of organic spacer for qua si-2D DJ lead-free perovskites.

关键词： Chain lengths Organic spacers Quantum well Carrier transport Lattice distortion

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Discovery of a potential bladder cancer inhibitor CHNQD-01281 by regulating EGFR and promoting infiltration of cytotoxic T cells

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Marine Life Science & Technology 2024年第3期6卷 502-514页

作者： Jian-Yu Liu yao-yao Jiang Peng-Jie Li Bo yao Yi-Jing Song Ji-Xiu Gao Gulab Said Yang Gao Jun-Yu Lai chang-Lun Shao Key Laboratory of Marine Drugs the Ministry of Education of ChinaSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China Department of Critical Care Medicine the Affiliated Hospital of Qingdao UniversityQingdao 266003China Department of Chemistry Women University SwabiSwabi 23430Pakistan Laoshan Laboratory Qingdao 266237China Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education College of Chemistry and Chemical EngineeringHainan Normal UniversityHaikou 571158China

As one of the common malignancies that threaten human life,bladder cancer occurs frequently with a high mortality rate in the world,due to its invasion,recurrence and drug *** products from marine microorganisms are becoming the hotspots in discovery of new candidate drug entities,especially in the area of *** A(BFA)is a natural Arf-GEFs inhibitor,but due to the low aqueous solubility,strong toxicity,and poor bioavailability,it is urgent to conduct structural optimization ***,a new BFA pyridine acrylate derivative CHNQD-01281 with improved solubility was prepared and found to exert moderate to strong antiproliferative activity on a variety of human cancer cell *** was noteworthy that CHNQD-01281 was most sensitive to two bladder cancer cell lines T24 and J82(IC50=0.079 and 0.081μmol/L)with high selectivity index(SI=14.68 and 14.32),suggesting a superior safety to *** vivo studies revealed that CHNQD-01281 remarkably suppressed tumor growth in a T24 nude mice xenograft model(TGI=52.63%)and prolonged the survival time(ILS=68.16%)in an MB49 allogeneic mouse model via inducing infiltration of cytotoxic T *** mechanism exploration indicated that CHNQD-01281 regulated both EGFR/PI3K/AKT and EGFR/ERK pathways and mediated the chemotactic effect of chemokines on immune effector ***,CHNQD-01281 may serve as a potential therapeutic agent for bladder cancer through multiple mechanisms.

关键词： Bladder cancer Marine natural products Brefeldin A EGFR/PI3K/AKT EGFR/ERK T-cell infiltration

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