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从“湿胜则阳微”论阳虚质特征

中国中医基础医学杂志 2007年第2期13卷 91-91,103页

作者：姚实林王琦安徽中医学院安徽合肥230038 北京中医药大学北京100029

阳虚质是一种基本的中医体质类型，它是个体在形态结构、生理功能和心理特征方面的固有特质。古代医家常将阳虚质称为“阳虚之体”、“阳气素虚”、“阳气素弱”、“阳虚之质”、“阴脏人”、“阴盛阳虚之质”、“阳虚禀质”、“素体阳... 详细信息

阳虚质是一种基本的中医体质类型，它是个体在形态结构、生理功能和心理特征方面的固有特质。古代医家常将阳虚质称为“阳虚之体”、“阳气素虚”、“阳气素弱”、“阳虚之质”、“阴脏人”、“阴盛阳虚之质”、“阳虚禀质”、“素体阳虚”、“阳气素不强”、“阴盛之体”、“阳气素虚之体质”、“中焦阳气素虚之人”。清代著名温病学家叶天士善于从面色、肌肤、形态划分体质类型，“湿胜则阳微”出自其著作《外感温热》：“吾吴湿邪害人最广，如面色白者，须要顾其阳气，湿胜则阳微也。法应清凉，然到十分之六七，即不可过于寒凉，恐成功反弃，何以故也？湿热一去，阳亦衰微也。”王士雄《温热经纬·卷三》引茅雨人语，谓“湿胜则阳微，其实乃阳微故致湿胜也。”曹元恒《温热论笺正·正文》日：“按此谓面色白者，其阳气素属不足。今为湿邪所困，湿胜则阳微矣，并非因阳微而致湿胜。”叶氏之语深刻揭示了阳虚质与治疗的关系，即素体阳虚之人，即使外感湿热之邪，清凉除湿之剂也不可过量，以免湿热尽去而阳气衰微。

关键词：体质阳虚质特征

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阳虚质成因论析

中国中医基础医学杂志 2008年第6期14卷 405-407页

作者：姚实林王琦安徽中医学院安徽合肥230038 北京中医药大学北京100029

从先天禀赋及后天因素两个方面对阳虚质的成因进行论析。在先天禀赋方面,亲代肾精不足、天癸不足和命火不足可致子代肾阳亏虚,继而形成阳虚质;孕母饮食不当或用药过于寒凉亦可导致子代阳虚质。在后天因素方面,社会环境影响、生活习惯不... 详细信息

从先天禀赋及后天因素两个方面对阳虚质的成因进行论析。在先天禀赋方面,亲代肾精不足、天癸不足和命火不足可致子代肾阳亏虚,继而形成阳虚质;孕母饮食不当或用药过于寒凉亦可导致子代阳虚质。在后天因素方面,社会环境影响、生活习惯不当(饮食所伤、嗜酒所伤、情志所伤、情欲房劳)、疾病影响及医过(误清、误汗、误下、误补)是损伤阳气的主要因素。对阳虚质成因的了解,有助于采取针对性措施干预阳虚质的偏颇。

关键词：阳虚质成因理论研究

Subsurface multi-physical characterization of mountain excavation and city construction in loess plateau with a fiber-optic sensing system

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第8期16卷 2935-2946页

作者： Jie Liu Bin shi Kai Gu Meng-Ya Sun Jun-Cheng yao He-Ming Han School of Earth Sciences and Engineering Nanjing UniversityNanjingJiangsu210023China Frontiers Science Center for Critical Earth Material Cycling Nanjing UniversityNanjing210023China School of Earth Sciences and Engineering Hohai UniversityNanjing210098China

Mountain excavation and city construction(MECC)projects being launched in the Loess Plateau in China involve the creation of large-scale artificial *** the subsurface evolution characteristics of the artificial land is essential,yet ***,we use an improved fiber-optic monitoring system for its subsurface multi-physical *** system enables us to gather spatiotemporal distribution of various parameters,including strata deformation,temperature,and ***’an New District was selected as a case study to conduct refined in-situ monitoring through a 77 m-deep borehole and a 30 m-long *** reveal that the ground settlement involves both the deformation of the filling loess and the underlying intact ***,the filling loess exhibits a stronger creep capability compared to underlying intact *** deformation along the profile is unevenly distributed,with a positive correlation with soil *** accumulation has been observed at the interface between the filling loess and the underlying intact loess,leading to a significant ***,the temperature and moisture in the filling loess have reached a new equilibrium state,with their depths influenced by atmospheric conditions measuring at 31 m and 26 m,*** refined investigation allows us to identify critical layers that matter the sustainable development of newly created urban areas,and provide improved insights into the evolution mechanisms of land creation.

关键词： Mountain excavation and city construction Fiber-optic monitoring Multi-physical characterization Compacted loess

Intra-Oceanic Subduction Termination and Reinitiation of the Eastern Neo-Tethys in Myanmar

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Journal of Earth Science 2024年第3期35卷 1053-1058页

作者： Yi Chen Qinghua Zhang lin Chen Kaihui shi Kyaing Sein State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China Myanmar Geosciences Society Hlaing University CampusYangon 11062Myanmar

Subduction initiation and termination represent the birth and death of a subduction zone and are inevitable elements of terrestrial plate *** evidence demonstrates that subduction zone processes did not operate continuously and might involve multiple initiation and termination stages(Stern,2004),characterized by sustained subduction-zone death and *** geological and numerical studies focus on subduction initiation processes/mechanisms(see reviews in Yang,2022);however,subduction termination is often studied numerically at continental margins(Gerya,2022).How subduction termination proceeds in intra-oceanic settings remains enigmatic due to lacking geological records.

关键词： Eastern terrestrial continental

Adaptively Enhancing Facial Expression Crucial Regions via a Local Non-local Joint Network

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Machine Intelligence Research 2024年第2期21卷 331-348页

作者： Guanghui shi Shasha Mao Shuiping Gou Dandan Yan Licheng Jiao lin Xiong School of Artificial Intelligence Xidian UniversityXi'an 710000China Applied Research Laboratory Sense TimeXi'an 710000China

Facial expression recognition(FER)is still challenging due to the small interclass discrepancy in facial expression *** view of the significance of facial crucial regions for FER,many existing studies utilize the prior information from some annotated crucial points to improve the performance of ***,it is complicated and time-consuming to manually annotate facial crucial points,especially for vast wild expression *** on this,a local non-local joint network is proposed to adaptively enhance the facial crucial regions in feature learning of FER in this *** the proposed method,two parts are constructed based on facial local and non-local information,where an ensemble of multiple local networks is proposed to extract local features corresponding to multiple facial local regions and a non-local attention network is addressed to explore the significance of each local *** particular,the attention weights obtained by the non-local network are fed into the local part to achieve interactive feedback between the facial global and local ***,the non-local weights corresponding to local regions are gradually updated and higher weights are given to more crucial ***,U-Net is employed to extract the integrated features of deep semantic information and low hierarchical detail information of expression ***,experimental results illustrate that the proposed method achieves more competitive performance than several state-of-the-art methods on five benchmark datasets.

关键词： Facial expression recognition deep neural network multiple network ensemble attention network facial crucial regions

Achieving highly efficient long-wavelength phosphorescence emission of large singlet-triplet energy gap materials by host-guest doping

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Science China Chemistry 2024年第6期67卷 1922-1928页

作者： Shasha Zhang Wei yao Anqi Lv Kun Liu Yusheng Zhang Chifeng Zhou Huili Ma Huifang shi Zhongfu An Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Nanjing Tech UniversityNanjing211816China

High-efficiency long-wavelength phosphorescence emissions of large singlet-triplet energy gap(ΔE_(ST))materials are essential for applications in biology and ***,few long-wavelength phosphorescence emissions of largeΔE_(ST)materials have been reported due to the weak spin-orbit coupling(SOC)and strong non-radiative ***,we develop a strategy to achieve highly efficient long-wavelength room temperature phosphorescence(RTP)emission of largeΔE_(ST)materials,which display bright red RTP emission with above 400μs lifetime and 6.5%phosphorescent quantum *** experiments and theoretical calculations reveal that the fishbone-like packing and the zig-zag interactions provide favorable conditions for suppressing the non-radiative transitions of triplet state excitons,and heavy atoms effectively promote the intersystem crossing(ISC)process for highly efficient long-wavelength phosphorescence *** universality of the method for highly efficient long-wavelength RTP emission of largeΔE_(ST)materials was further investigated in various ***,these materials with largeΔE_(ST)manifest the advantages of large color contrast on the display and utilization potentiality in information *** strategy paves the way for the high contrast display and development of information encryption with RTP emission.

关键词： room temperature phosphorescence singlet-triplet energy gap host-guest doping heavy atom effect red phosphorescence

Effect and mechanism of Qingre Huashi decoction on drug-resistant Helicobacter pylori

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World Journal of Gastroenterology 2024年第24期30卷 3086-3105页

作者： Miao-Miao lin Shan-Shan Yang Qiu-Yue Huang Guang-Hui Cui Xiao-Fen Jia yao Yang Zong-Ming shi Hui Ye Xue-Zhi Zhang Department of Integrated Traditional Chinese and Western Medicine Peking University First HospitalBeijing 100034China Institute of Integrated Traditional Chinese and Western Medicine Peking UniversityBeijing 100034China

BACKGROUND Helicobacter pylori(HP),the most common pathogenic microorganism in stomach,can induce inflammatory reactions in the gastric mucosa,causing chronic gastritis and even gastric *** infection affects over 4.4 billion people globally,with a worldwide infection rate of up to 50%.The multidrug resistance of HP poses a serious challenge to *** has been monstrated that compared to bismuth quadruple therapy,Qingre Huashi decoction(QHD)combined with triple therapy exhibits comparable eradication rates but with a lower incidence of adverse reactions;in addition,QHD directly inhibit and kill HP in *** In this study,12 HP strains were isolated in vitro after biopsy during gastroscopy of HP-infected *** vitro,the minimum inhibitory concentration(MIC)values for clinical HP strains and biofilm quantification were determined through the E-test method and crystal violet staining,*** most robust biofilm-forming strain of HP was selected,and QHD was evaluated for its inhibitory and bactericidal effects on the strain with strong biofilm *** assessment was performed using agar dilution,E-test,killing dynamics,and transmission electron microscopy(TEM).The study also explored the impact of QHD on antibiotic resistance in these HP strains with strong biofilm *** violet method,scanning electron microscopy,laser confocal scanning microscopy,and(p)ppGpp chromatographic identification were employed to evaluate the effect of QHD on biofilm in strong biofilm-forming HP *** effect of QHD on biofilm and efflux pump-related gene expression was evaluated by quantitative polymerase chain ***-targeted metabolomics with UHPLC-MS/MS was used to identify potential metabolic pathways and biomarkers which were different between the NC and QHD *** HP could form biofilms of different degrees in vitro,and the intensity of formation was associated with the drug resistance of the *** had str

关键词： Qingre Huashi decoction Helicobacter pylori Drug resistance Biofilm Metabolomics

Alloy strategy to synthesize Pt-early transition metal oxide interfacial catalysts

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Nano Research 2024年第4期17卷 3390-3397页

作者： shi-Long Xu Hang Nan Wanqun Zhang Yue lin Sheng-Qi Chu Hai-Wei Liang Hefei National Research Center for Physical Sciences at the Microscale Department of ChemistryUniversity of Science and Technology of ChinaHefei 230026China School of Materials and Chemical Engineering Anhui Jianzhu UniversityHefei 230601China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Metal oxide supported metal catalysts show promising catalytic performance in many industry-relevant ***,the enhancement of performance is often limited by the insufficient metal/metal oxide *** this work,we demonstrate a general synthesis of Pt-early transition metal oxide(Pt-MO_(x),M=Ti,Zr,V,and Y)catalysts with rich interfacial sites,which is based on the air-induced surface segregation and oxidation of M in the supported Pt-M alloy *** characterizations verify the dynamic structural response of Pt-M alloy catalysts to air and the formation of Pt-MO_(x) catalysts with abundant interfacial *** prepared Pt-TiO_(x) interfacial catalysts exhibit improved performance in hydrogenation reactions of benzaldehyde,nitrobenzene,styrene,and furfural,as a result of the heterolytic dissociation of H_(2) at Pt-metal oxide interfacial sites.

关键词： Pt-early transition metal oxide interfacial catalyst alloy oxidation strategy interfacial sites hydrogenation reactions heterolytic dissociation

Electrochemical Dearomative Spirocyclization of N-Acyl Sulfonamides in a Continuous-Flow Cell

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Chinese Journal of Chemistry 2024年第9期42卷 980-984页

作者： Ting Liu Zhaojiang shi yaofeng Yuan Yuqi lin Ke-Yin Ye Key Laboratory of Molecule Synthesis and Function Discovery(Fujian Province University) College of ChemistryFuzhou University FuzhouFujian350108China

The development of efficient and sustainable methods to obtain spirocyclic compounds is of significance as these structures are widely found in pharmaceuticals and ***,we disclose an electrochemical dearomative spirocyclization of N-acyl sulfonamides in a continuous-flow *** reaction is simple and efficient without external catalysts or supporting electrolytes and could be applied in a decagram-scale synthesis.

关键词： Electrochemistry Continuous-flow Dearomatization Spirocyclization Sulfonamides Cyclization Methodology and reactions