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General Psychiatry 2023年第6期36卷 552-556页

作者： Longtao Yang Lijie Zhang Wenhan Yang Fei Tang yanyao du Jun Liu Department of Radiology The Second Xiangya HospitalCentral South UniversityChangshaHunanChina Clinical Research Center for Medical Imaging in Hunan Province ChangshaHunanChina Department of Radiology Quality Control Center in Hunan Province ChangshaHunanChina

INTROduCTION,Drug addiction is a chronic and recurrent encephalopathy characterised by impulsive behaviour,spiritual cravings,psychological distortion and physical damage!'According to the role of molecular biology mechanisms on the central nervous system,addictive substances can be classified as inhibitors(eg,opioids,etc),stimulants(eg,methamphetamine(MA),nicotine,cocaine,etc)and hallucinogens(eg,cannabis,etc).As published by the World Drug Report 2022,over284million individualsaged 15-64 worldwide have reportedly abused drugs in the past 12 months,emphasising the international challenge of effective detox treatment.

关键词： behaviour distortion potential

Connectome-based predictive modelling can predict follow-up craving after abstinence in individuals with opioid use disorders

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General Psychiatry 2023年第6期36卷 472-480页

作者： Wenhan Yang Jungong Han Jing Luo Fei Tang Li Fan yanyao du Longtao Yang Jun Zhang Huiting Zhang Jun Liu The Second Xiangya Hospital of Central South University ChangshaHunanChina Department of Computer Science Aberystwyth UniversityAberystwythUK Department of Radiology The Second Xiangya Hospital of Central South UniversityChangshaHunanChina Hunan Judicial Police Academy ChangshaHunanChina siemens Healthineers Ltd WuhanHubeiChina Clinical Research Center for Medical Imaging in Hunan Province ChangshaHunanChina Department of Radiology Quality Control Center in Hunan Province ChangshaHunanChina

Background Individual differences have been detected in individuals with opioid use disorders(OUD)in rehabilitation following protracted abstinence.Recent studies suggested that prediction models were effective for individual-level prognosis based on neuroimage data in substance use disorders(SUD).Aims This prospective cohort study aimed to assess neuroimaging biomarkers for individual response to protracted abstinence in opioid users using connectome-based predictive modelling(CPM).Methods One hundred and eight inpatients with OUD underwent structural and functional magnetic resonance imaging(fMRI)scans at baseline.The Heroin Craving Questionnaire(HCQ)was used to assess craving levels at baseline and at the 8-month follow-up of abstinence.CPM with leave-one-out cross-validation was used to identify baseline networks that could predict follow-up HCQ scores and changes in HCQ(HCQtolow V-up-HCQpa baseline).Then,the follow-up aseline predictive ability of identified networks was tested in a separate,heterogeneous sample of methamphetamine individuals who underwent MRI scanning before abstinence for SUD.Results CPM could predict craving changes induced by long-term abstinence,as shown by a significant correlation between predicted and actual HCQ fllow-up(r=0.417,pduals after protracted abstinence,as well as the generalisation ability;the identified brain networks might be the focus of innovative therapies in the future.

关键词： opioid disorders network

Neuropsychiatric symptoms associated with the COVID-19 and its potential nervous system infection mechanism:the role of imaging in the study

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Psychoradiology 2021年第4期1卷 199-211页

作者： yanyao du Wei Zhao Lei du Jun Liu Department of Radiology Second Xiangya Hospital of Central South UniversityChangsha 410011Hunan ProvinceChina Clinical Research Center for Medical Imaging in Hunan Province Changsha 410011HunanChina Department of Psychiatry and Behavioral Neuroscience University of Cincinnati College of MedicineCincinnati 45255OHUSA Department of Radiology Quality Control Center Hunan ProvinceChangsha 410011HunanChina

The epidemic of coronavirus disease 2019(COVID-19)has broken the normal spread mode of respiratory viruses,namely,mainly spread in winter,resulting in over 230 million confirmed cases of COVID-19.Many studies have shown that severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)can affect the nervous system by varying degrees.In this review,we look at the acute neuropsychiatric impacts of COVID-19 patients,including acute ischemic stroke,encephalitis,acute necrotizing encephalopathy,dysosmia,and epilepsy,as well as the long-term neuropsychiatric sequelae of COVID-19 survivors:mental disorder and neurodegenerative diseases.In particular,this review discusses long-term changes in brain structure and function associated with COVID-19 infection.We believe that the traditional imaging sequences are important in the acute phase,while the nontraditional imaging sequences are more meaningful for the detection of long-term neuropsychiatric sequelae.These long-term follow-up changes in structure and function may also help us understand the causes of neuropsychiatric symptoms in COVID-19 survivors.Finally,we review previous studies and discuss some potential mechanisms of SARS-CoV-2 infection in the nervous system.Continuous focus on neuropsychiatric sequelae and a comprehensive understanding of the long-term impacts of the virus to the nervous system is significant for formulating effective sequelae prevention andmanagement strategies,andmay provide important clues for nervous system damage in future public health crises.

关键词： COVID-19 SARS-CoV-2 nervous system imaging sequences pathogenesis neuropsychiatric sequelae brain function alteration

重回文学本身:方法与意义——以张清华的“文学性研究”为讨论中心

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当代文坛 2024年第2期 33-39页

作者：蔡岩峣北京师范大学文学院

张清华的“文学性研究”可以归纳出四个方面的方法与意义。首先是“潜结构”与“潜叙事”理论,其对文学形式的强调,不仅能解决革命叙事文学中的“文学性”问题,也可以推广至先锋文学等其他文学类型的研究。其次,对于人文主义价值的坚守... 详细信息

张清华的“文学性研究”可以归纳出四个方面的方法与意义。首先是“潜结构”与“潜叙事”理论,其对文学形式的强调,不仅能解决革命叙事文学中的“文学性”问题,也可以推广至先锋文学等其他文学类型的研究。其次,对于人文主义价值的坚守,建立以普通个体生命与存在主义哲学相合的人文批评观,可以有效弥补新世纪以来文学价值判断的缺失问题。再次,以“细读”和“作家论”批评等方式建构当代文学经典,可以有效抵御“文化研究”(文化批评)对当代文学“文学性”价值的质疑。最后,在写作研究文章时充分运用“诗性文体”,这不仅可以视作文学研究与“文学性”的同构,也可以从中发现张清华对文学整全历史判断的诗性追求。

关键词：文学性研究潜结构与潜叙事生命本体论诗学经典诗性文体

注射用复方骨肽联合常规用药治疗跟骨骨折术后患者的效果

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中国民康医学 2024年第13期36卷 65-67页

作者：郭彦耀开封市第二中医院药剂科河南开封475000

目的:观察注射用复方骨肽联合常规用药治疗跟骨骨折术后患者的效果。方法:选取2022年6月至2023年6月该院收治的62例跟骨骨折术后患者进行前瞻性研究,按照随机数字表法分为研究组与对照组各31例。对照组术后常规用药治疗,研究组在对照组... 详细信息

目的:观察注射用复方骨肽联合常规用药治疗跟骨骨折术后患者的效果。方法:选取2022年6月至2023年6月该院收治的62例跟骨骨折术后患者进行前瞻性研究,按照随机数字表法分为研究组与对照组各31例。对照组术后常规用药治疗,研究组在对照组基础上增加注射用复方骨肽治疗,比较两组小腿周径差、患肢肿胀度评分、血清骨代谢指标[骨钙素、骨碱性磷酸酶(BALP)]水平、炎性指标[血清C反应蛋白(CRP)、白细胞计数(WBC)]水平、疼痛视觉模拟评分法(VAS)评分和并发症发生率。结果:术后2周,血清骨钙素、BALP等血清骨代谢指标水平高于术后1 d,且研究组高于对照组,两组小腿周径差、患肢肿胀度评分、CRP水平、WBC水平、VAS评分低于术后1 d,且研究组低于对照组,差异均有统计学意义(P0.05)。结论:注射用复方骨肽联合常规用药治疗跟骨骨折术后患者可提高其骨代谢指标水平,降低小腿周径差、患肢肿胀度评分、VAS评分以及炎性指标水平,效果优于单纯常规用药治疗。

关键词：注射用复方骨肽跟骨骨折术后骨代谢小腿周径患肢肿胀度并发症

94 GHz频段FOD探测雷达与云雾多普勒监测雷达频率兼容性分析

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数字通信世界 2024年第6期 133-136,139页

作者：赵燚张彦垚国家无线电监测中心检测中心北京100041 成都市无线电监测站四川成都610000

随着毫米波雷达技术的发展及其广泛应用,面向小目标探测、高精度测量等应用领域的雷达设备频率选择不断朝高频毫米波方向发展。根据电磁波大气传播特性,94 GHz频率附近存在一个大气衰减较小的电磁波传播窗口。

关键词：机场跑道异物(FOD) 云雾多普勒兼容性

基于扎根理论的服装设计师品牌孵化影响因素研究

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中国商论 2024年第9期 79-83页

作者：王焰瑶白玉苓北京服装学院北京100029

在经济迅速发展的当下,消费者个性化的需求为服装设计师品牌的成长与发展提供了土壤,吸引了不少设计师创建和孵化新品牌。本文以我国服装设计师品牌为研究对象,通过访谈及扎根理论方法,探索服装设计师品牌孵化的影响因素,发现影响服装... 详细信息

在经济迅速发展的当下,消费者个性化的需求为服装设计师品牌的成长与发展提供了土壤,吸引了不少设计师创建和孵化新品牌。本文以我国服装设计师品牌为研究对象,通过访谈及扎根理论方法,探索服装设计师品牌孵化的影响因素,发现影响服装设计师品牌孵化的因素主要包括品牌特征、供应链资源和所选择的营销模式,并探讨了各个因素的构成维度,得出品牌孵化各影响因素之间的关系逻辑,为我国服装设计师品牌孵化提出相应的对策建议,以供参考。

关键词：服装设计师品牌品牌孵化供应链资料构成围度扎根理论

添加Al(NO_(3))_(3)对镁合金表面水滑石蒸汽涂层耐蚀性能的影响

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表面技术 2024年第9期53卷 43-55,74页

作者：马言耀潘仕琪张芬崔蓝月李硕琦刘成宝曾荣昌山东科技大学材料科学与工程学院山东青岛266590

目的研究原位蒸汽法制备层状双金属氢氧化物(LDH)的反应机理,以及添加Al(NO_(3))_(3)对AZ91D镁合金表面水滑石蒸汽涂层耐蚀性的影响和耐蚀机理。方法在蒸汽源中添加不同浓度的Al(NO_(3))_(3),以提供Al3+,采用原位蒸汽法在150℃下进行5 ... 详细信息

目的研究原位蒸汽法制备层状双金属氢氧化物(LDH)的反应机理,以及添加Al(NO_(3))_(3)对AZ91D镁合金表面水滑石蒸汽涂层耐蚀性的影响和耐蚀机理。方法在蒸汽源中添加不同浓度的Al(NO_(3))_(3),以提供Al3+,采用原位蒸汽法在150℃下进行5 h水热反应,在AZ91D镁合金表面制备水滑石蒸汽涂层。使用XRD、FT-IR、SEM、EDS等测试手段对水滑石蒸汽涂层进行表征,通过动电位极化、电化学阻抗和盐雾试验,研究水滑石蒸汽涂层的生长机理及腐蚀机理。结果基于不同浓度梯度的Al(NO_(3))_(3),在AZ91D镁合金表面成功制备了水滑石蒸汽涂层,涂层的主要组成物相为Mg(OH)_(2)、Mg-Al-NO_(3)LDH、Mg-Al-CO_(2)LDH。Al(NO_(3))_(3)/LDH相较于未添加Al(NO_(3))_(3)得到的LDH,其生长均匀、结构致密,耐腐蚀性能由大到小的顺序为LDH-100、LDH-200、LDH-50、LDH-20、LDH、AZ91D镁合金。水滑石蒸汽涂层的腐蚀产物主要为Mg(OH)_(2)、MgCO_(3)。结论在添加100 mmol/L的Al(NO_(3))_(3)作为蒸汽源时,充足的Al^(3+)保证了合成结构致密水滑石的需要,副产物最少,且耐蚀性最好。最后,讨论了水滑石蒸汽涂层的生长机理和腐蚀机理。

关键词：镁合金水滑石原位蒸汽法耐蚀性能成膜机理

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Do trace metal(loid)s in road soils pose health risks to tourists?A case of a highly-visited national park in China

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Journal of Environmental Sciences 2022年第1期34卷 61-74页

作者： Jingling Huang Yuying Wu yanyao Li Jiaxun Sun Yujing Xie Zhengqiu Fan Department of Environmental Science and Engineering Fudan UniversityShanghai 200433China

Nowadays,more people tend to spend their recreational time in large national parks,and trace metal(loid)s in soils have attracted long-term attention due to their possible harm to human health.To investigate the pollution levels,potential sources and health risks of trace metal(loid)s in road soils,a total of eight trace metal(loid)s(including As,Cd,Cr,Cu,Ni,Pb,Zn and Hg)from 47 soil samples along roads were studied in the Huangshan National Park in Southeast China.The results showed that the concentrations of As,Cd,Pb,Zn and Hg appeared different degrees of pollution compared with their corresponding background values.According to the pollution indices,Hg and Cd were recognized as significant pollutants presenting moderate to high ecological risk.Combining principal component analysis and positive matrix factorization model,the results showed that traffic,industrial,agricultural and natural sources were the potential origins of trace metal(loid)s in this area,with contribution rates of 39.93%,25.92%,10.53%and 23.62%,respectively.Non-carcinogenic risks were all negligible,while the carcinogenic risk of As was higher than the limit(1×10^(-6)).Moreover,children were more susceptible to trace metal(loid)s by ingestion which appeared to be a more important exposure pathway than dermal contact and inhalation.The contribution rates of different sources to non-carcinogenic risks and carcinogenic risks were similar among children and adults,while traffic and industrial sources have a significant impact on health risks.This study will give more insights to control the environmental risks of trace metal(loid)s in national parks.

关键词： Trace metal(loid)s Pollution assessment Source apportionment Health risk assessment National park

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贮藏期间亚硝酸钠对滩羊肉品质特性的影响

食品与发酵工业 2024年第11期50卷 209-215页

作者：杨世虎刘贵珊张远绿吴迪王延尧郭美宁夏大学食品与葡萄酒学院宁夏银川750021

以滩羊肉为研究对象,探究亚硝酸钠添加量(0、50、100、150 mg/kg)对(4±1)℃条件下贮藏0、3、6、9、12、15 d后滩羊肉感官品质、色泽、p H、蒸煮损失、高铁肌红蛋白含量、硫代巴比妥酸(thiobarbituric acid reactive substances,TBARS)... 详细信息

以滩羊肉为研究对象,探究亚硝酸钠添加量(0、50、100、150 mg/kg)对(4±1)℃条件下贮藏0、3、6、9、12、15 d后滩羊肉感官品质、色泽、p H、蒸煮损失、高铁肌红蛋白含量、硫代巴比妥酸(thiobarbituric acid reactive substances,TBARS)的影响。结果表明,随着亚硝酸钠添加量的增加,腌制滩羊肉在贮藏期间感官品质得到改善。与对照组相比,在贮藏第15天时,添加量100 mg/kg亚硝酸钠样品a^(*)值上升(P<0.05),L^(*)值和b^(*)值降低,蒸煮损失变化不显著,同时p H值下降0.77%,高铁肌红蛋白含量下降12.91%,TBARS值下降8.24%。此外,相关性分析表明,亚硝酸钠添加量与a^(*)、L^(*)、b^(*)极显著相关(P<0.01),其他各个生理指标间也存在一定相关性。总体来看,添加亚硝酸钠能够改善滩羊肉的色泽,有效减缓其脂肪和蛋白质的氧化。因此,从健康角度出发,确定腌制滩羊肉中亚硝酸钠添加量为100 mg/kg,可在一定程度上改善滩羊肉的品质,这为滩羊肉制品的精深加工提供理论基础。

关键词：滩羊肉亚硝酸钠品质特性相关性分析