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Association of interpregnancy interval and risk of adverse pregnancy outcomes in woman by different previous gestational ages

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Chinese Medical Journal 2024年第1期137卷 87-96页

作者： Peiran Chen Yi Mu Zheng Liu Yanping Wang Xiaohong Li Li Dai Qi Li Mingrong Li yanxia xie Juan Liang Jun Zhu National Office for Maternal and Child Health Surveillance of China West China Second University HospitalSichuan UniversityChengduSichuan 610066China Department of Obstetrics West China Second University HospitalSichuan UniversityChengduSichuan 610066China Key Laboratory of Birth Defects and Related Diseases of Women and Children Ministry of EducationSichuan UniversityChengduSichuan 610066China

Background:With an increasing proportion of multiparas,proper interpregnancy intervals(IPIs)are urgently ***,the association between IPIs and adverse perinatal outcomes has always been *** study aimed to explore the association between IPIs and adverse outcomes in different fertility policy periods and for different previous gestational ***:We used individual data from China’s National Maternal Near Miss Surveillance System between 2014 and *** Poisson models with restricted cubic splines were *** adverse outcome was analyzed separately in the overall model and stratified *** stratified models included different categories of fertility policy periods(2014-2015,2016-2017,and 2018-2019)and infant gestational age in previous pregnancy(<28 weeks,28-36 weeks,and≥37 weeks).Results:There were 781,731 pregnancies enrolled in this study.A short IPI(≤6 months)was associated with an increased risk of preterm birth(OR[95%CI]:1.63[1.55,1.71]for vaginal delivery[VD]and 1.10[1.03,1.19]for cesarean section[CS]),low Apgar scores and small for gestational age(SGA),and a decreased risk of diabetes mellitus in pregnancy,preeclampsia or eclampsia,and gestational hypertension.A long IPI(≥60 months)was associated with an increased risk of preterm birth(OR[95%CI]:1.18[1.11,1.26]for VD and 1.39[1.32,1.47]for CS),placenta previa,postpartum hemorrhage,diabetes mellitus in pregnancy,preeclampsia or eclampsia,and gestational *** policy changes had little effect on the association of IPIs and adverse maternal and neonatal *** estimated risk of preterm birth,low Apgar scores,SGA,diabetes mellitus in pregnancy,and gestational hypertension was more profound among women with previous term births than among those with preterm births or pregnancy ***:For pregnant women with shorter or longer IPIs,more targeted health care measures during pregnancy should be formulated according to infant gestational age in

关键词： Interpregnancy interval Fertility policy Gestational age Preterm birth Gestational hypertension Diabetes mellitus in pregnancy

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商用聚对苯二甲酸乙二醇酯短纤维中低聚物析出机制及影响因素

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纺织学报 2024年第1期45卷 65-73页

作者：谢艳霞张唯强徐亚宁赵书涵尹雯萱张文强韩旭安徽工程大学纺织服装学院安徽芜湖241000 安徽省纺织工程技术研究中心安徽芜湖241000 滁州霞客无染彩色纺有限公司安徽滁州239000

为分析商用聚对苯二甲酸乙二醇酯(PET)短纤维低聚物析出的主要原因,筛选低聚物脱落性能差别显著的2种短纤维进行溶剂萃取和热诱导,制得萃取纤维、热诱导纤维和低聚物,基于其外观形貌、热性能和结晶结构等测试,分析低聚物结构组分及其析... 详细信息

为分析商用聚对苯二甲酸乙二醇酯(PET)短纤维低聚物析出的主要原因,筛选低聚物脱落性能差别显著的2种短纤维进行溶剂萃取和热诱导,制得萃取纤维、热诱导纤维和低聚物,基于其外观形貌、热性能和结晶结构等测试,分析低聚物结构组分及其析出规律与原理。结果表明:2种萃取低聚物的主要成分均为环状三聚体(C 3)和少量PET微晶聚合物,表面低聚物较多的PET短纤维(HM)含有可能是环状四聚体(C 4)的高熔点低聚物;HM低聚物的C 3和PET微晶的熔点相对较高,分别为173.5和146.7℃;C 3在短纤维、萃取低聚物和高温过程分别主要以A、B和A/B混合型晶型存在,HM低聚物的A和B型C 3的熔点相对较高,分别为173.5和314.5℃;2种纤维的低聚物含量相近,与表面低聚物较少的PET短纤维(LM)相比,HM短纤维的结晶度相对偏低11.25%,其A型C 3含量相对偏少,熔点偏高1.7℃,B型C 3的熔点偏高1.9℃,且含二甘醇残基的环聚物含量相对略高;对2种纤维在140~200℃进行热空气热诱导1 h发现,在140、160和180℃时,低聚物析出量均随温度升高而增加,但HM短纤维析出明显较少,在200℃时低聚物析出量均快速增多,晶型和数量均趋于一致;热诱导作用是影响低聚物析出的主要因素,纤维后加工的热处理条件、纤维结晶度和聚合过程中乙二醇/对苯二甲酸的质量比可能是析出的重要因素。

关键词：聚对苯二甲酸乙二醇酯短纤维低聚物析出热诱导环聚物环状三聚体

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Disparities of Heatwave-Related Preterm Birth in Climate Types—China,2012-2019

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China CDC weekly 2023年第49期5卷 1093-1099,I0001,I0002页

作者： Yafei Guo yanxia xie Xiaohui Wei Chenran Guo Peiran Chen Yanping Wang Yi Mu Xiaoming Shi Jun Zhu Juan Liang Qiyong Liu National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina Chinese Center for Disease Control and Prevention Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina National Office for Maternal and Child Health Surveillance of China West China Second University HospitalSichuan UniversityChengdu CitySichuan ProvinceChina Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University) Ministry of EducationChengdu CitySichuan ProvinceChina School of Public Health Nanjing Medical UniversityNanjing CityJiangsu ProvinceChina Chinese Center for Disease Control and Prevention BeijingChina.

What is already known about this topic?An association between prenatal heatwave exposure and the risk of preterm birth was ***,the disparities in heatwave-related preterm birth across different climate types have not been *** is added by this report?This nationwide case-crossover study investigated the association between heatwave exposure and preterm birth across different Köppen-Geiger climate *** pregnant women residing in the arid-desertcold climate type,exposure to compound heatwaves was found to be associated with a significantly higher risk of preterm birth{adjusted odds ratios(AORs)ranged from 1.55[95%confidence interval(CI):1.21-1.97]to 2.11(95%CI:1.35-3.31)}.In contrast,among pregnant women residing in the tropical monsoonal climate type,exposure to daytime-only heatwaves was associated with an increased risk of preterm birth[AORs ranged from 1.25(95%CI:1.03-1.51)to 1.37(95%CI:1.05-1.77)].

关键词： climate monsoon tropical

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Temporal Trends of Maternal Mortality Due to Obstetric Hemorrhage in Chinese Mainland: Evidence from the Population-Based Surveillance Data Between 2000 and 2019

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Maternal-Fetal Medicine 2022年第3期4卷 169-178页

作者： Yi Mu Jun Zhu Yanping Wang Jiani Zhang Mingrong Li Peiran Chen yanxia xie Juan Liang Xiaodong Wang National Office for Maternal and Child Health Surveillance of China West China Second University HospitalSichuan UniversityChengdu 610041China Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University) Ministry of EducationChengdu 610041China Department of Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China.

Objective:To analyze the temporal trends of maternal mortality ratio(MMR)due to obstetric hemorrhage and its specific causes in Chinese mainland from 2000 to 2019,to identify whether the rate of change has accelerated or slowed down during this period,and to find the prior cause of obstetric hemorrhage that needs to be intervened in the ***:Individual information on maternal deaths and total number of live births from 336 surveillance sites across 31 provinces in Chinese mainland was collected from the National Maternal and Child Health Surveillance System between 2000 and *** death was defined according to the World Health Organization’s *** final underlying cause of death was confirmed by the national review and was coded according to International Classification of *** trends for changes in characteristics of maternal deaths were assessed using linear or logistic models with the year treated as a continuous *** MMR and 95%confidence intervals(CI)for regions or causes were estimated by Poisson’s *** regression was used to assess the accurate temporal ***:The national MMR due to obstetric hemorrhage was 18.4 per 100,000 live births(95%CI:15.0–22.2)in *** peaked in 2001(22.1 per 100,000 live births,95%CI:18.3–26.4)and was lowest in 2019(1.6 per 100,000 live births,95%CI:1.0–2.3).For specific regions,the MMR due to obstetric hemorrhage in rural areas and western regions both experienced a slight rise,followed by a rapid decline,and then a slow *** specific causes,no change point was found in joinpoint analysis of the national MMR caused by placenta previa,postpartum uterine atony,and retained placenta(the annual percent change was12.0%,10.5%,and21.0%,respectively).The MMR caused by postpartum hemorrhages(PPH)significantly declined by 8.0%(95%CI:1.9–13.6)per year from 2000 to *** annual percent change of MMR caused by PPH accelerated further to25.0%between 2007

关键词： Maternal mortality Obstetric haemorrhage Temporal trend Annual percent change China

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New insights into the correlations between circulating tumor cells and target organ metastasis

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Signal Transduction and Targeted Therapy 2024年第1期9卷 211-233页

作者： Qinru Zhan Bixia Liu Xiaohua Situ Yuting Luo Tongze Fu yanxia Wang Zhongpeng xie Lijuan Ren Ying Zhu Weiling He Zunfu Ke Department of Pathology The First Affiliated Hospital of Sun Yat-sen University510000 GuangzhouGuangdongP.R.China Institute of Precision Medicine The First Affiliated Hospital of Sun Yat-sen University510000 GuangzhouGuangdongP.R.China Zhongshan School of Medicine Sun Yat-sen University510000 GuangzhouGuangdongP.R.China Department of Radiology The First Affiliated Hospital of Sun Yat-sen University510000 GuangzhouGuangdongP.R.China Department of Microbiology and Immunology Weill Cornell MedicineNew YorkNY 10065USA School of Medicine Xiang’an Hospital of Xiamen UniversityXiamen University361000 XiamenFujianP.R.China

Organ-specific metastasis is the primary cause of cancer patient *** distant metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of the tumor cells and extrinsic factors in their *** an intermediate stage of metastasis,circulating tumor cells(CTCs)are released into the bloodstream from primary and metastatic *** harboring aggressive or metastatic features can extravasate to remote sites for continuous colonizing growth,leading to further *** the past decade,numerous studies demonstrated that CTCs exhibited huge clinical value including predicting distant metastasis,assessing prognosis and monitoring treatment response et ***,increasingly numerous experiments are dedicated to identifying the key molecules on or inside CTCs and exploring how they mediate CTC-related organ-specific *** on the above molecules,more and more inhibitors are being developed to target CTCs and being utilized to completely clean CTCs,which should provide promising prospects to administer advanced ***,the application of various nanomaterials and microfluidic technologies in CTCs enrichment technology has assisted to improve our deep insights into the phenotypic characteristics and biological functions of CTCs as a potential therapy target,which may pave the way for us to make practical clinical *** the present review,we mainly focus on the role of CTCs being involved in targeted organ metastasis,especially the latest molecular mechanism research and clinical intervention strategies related to CTCs.

关键词： metastasis organs insight

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基于关键点检测的航空发动机螺栓安装缺陷自动化检测方法

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仪器仪表学报 2023年第3期44卷 98-106页

作者：辛佳雯王睿谢艳霞孙军华北京航空航天大学仪器科学与光电工程学院精密光机电一体化教育部重点实验室北京100191

针对航空发动机螺栓存在背景复杂、目标小、且精细特征不明显的问题,本文研究了一种基于关键点检测的航空发动机螺栓安装缺陷的自动化检测方法。首先设计了基于Faster RCNN和改进CPN(AD-CPN)的级联卷积神经网络,实现了图像中螺栓及二维... 详细信息

针对航空发动机螺栓存在背景复杂、目标小、且精细特征不明显的问题,本文研究了一种基于关键点检测的航空发动机螺栓安装缺陷的自动化检测方法。首先设计了基于Faster RCNN和改进CPN(AD-CPN)的级联卷积神经网络,实现了图像中螺栓及二维关键点的检测,可判断该螺栓是否脱落、漏装。为进一步检测螺栓的三维安装缺陷,通过欧氏距离选择策略对已检测出的关键点进行双目匹配、筛选以获得检测点对,最后对检测点对三维重构,并计算出螺栓的实际长度,从而判断螺栓是否错装。实验结果表明,相较于CPN,AD-CPN的mAP、AP50、AP75分别提升了2.9%、3.3%、4%;螺栓测量长度的相对平均误差约为3.0%,可见该方法具有较高的缺陷检测准确率,有效保障了航空发动机的安全运行。

关键词：缺陷检测关键点检测深度学习双目立体视觉

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青藏高原中东部和四川盆地的夏季雨滴谱对比分析研究

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高原气象 2024年第1期43卷 28-41页

作者：刘艳霞文军谢晓林中国科学院西北生态环境资源研究院甘肃兰州730000 中国科学院大学北京100039 成都信息工程大学大气科学学院/高原大气与环境四川省重点实验室四川成都610225 四川省气象探测数据中心四川成都610072

为了进一步认识青藏高原中东部和下游四川盆地的降水微观特征和差异,本文利用2019年7-8月和2020年7-8月那曲、玉树、林芝、巴塘、泸定和成都6个地区的雨滴谱观测资料,研究了不同地区之间的雨滴谱特征和差异,并提出了各个地区降水的Gamm... 详细信息

为了进一步认识青藏高原中东部和下游四川盆地的降水微观特征和差异,本文利用2019年7-8月和2020年7-8月那曲、玉树、林芝、巴塘、泸定和成都6个地区的雨滴谱观测资料,研究了不同地区之间的雨滴谱特征和差异,并提出了各个地区降水的Gamma谱形状参数-斜率参数关系和反射率因子-雨强关系。结果表明:因更多强对流降水的贡献,盆地和邻近地区(成都和泸定)的雨滴谱整体比高原地区(那曲、玉树、林芝和巴塘)的更宽,中大雨滴(直径≥1.0 mm)数浓度更高;而高原地区的降水主要来自层云和弱对流,整体雨滴谱更窄,小雨滴(直径<1.0 mm)数浓度更高。6个地区的雨滴谱均随雨强增大而变宽,数浓度也逐渐升高。不同地区之间的雨滴谱差异也会随雨强变化而改变,当雨强超过0.1 mm·h-1后,那曲和林芝的小雨滴数浓度随雨强增大而增大的幅度明显比其他地区更大;当雨强达到5 mm·h-1后,成都和泸定的中大雨滴数浓度与其他高原地区的差异也逐渐变大。在谱形状参数相同情况下,成都和泸定的谱倾斜率更小,反映了这两个地区雨滴数浓度随粒径增大而减小的速率比高原地区的更慢。在相同雷达回波强度(反射率因子)情况下,那曲和林芝层云降水的雨强比其他地区大;林芝对流降水在雷达回波低于40 dBZ时,雨强也比其他地区的大,而那曲对流降水在雷达回波大于40 dBZ后,雨强比其他地区的小。

关键词：青藏高原四川盆地雨滴谱降水微观特征

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贝莱斯芽胞杆菌ZF145抑菌物质提取方法比较及成分鉴定

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植物保护学报 2024年第2期51卷 334-341页

作者：曾先锋覃诗扬谢学文石延霞柴阿丽李宝聚李磊中国农业科学院蔬菜花卉研究所蔬菜生物育种全国重点实验室北京100081 天津农学院园艺园林学院天津300384

为明确贝莱斯芽胞杆菌Bacillus velezensis菌株ZF145中可有效抑制黄瓜角斑病病原菌扁桃假单胞菌流泪致病变种Pseudomonas amygdali ***的主要物质,采用冻干法、酸沉法、絮凝法、萃取法和铵沉法提取菌株ZF145发酵液中的抑菌物质,通过室... 详细信息

为明确贝莱斯芽胞杆菌Bacillus velezensis菌株ZF145中可有效抑制黄瓜角斑病病原菌扁桃假单胞菌流泪致病变种Pseudomonas amygdali ***的主要物质,采用冻干法、酸沉法、絮凝法、萃取法和铵沉法提取菌株ZF145发酵液中的抑菌物质,通过室内盆栽试验验证粗提物对黄瓜角斑病的防治效果,综合比较不同方法的提取效果,并通过高效液相色谱-质谱(high performance liquid chromatography-mass spectrometry,HPLC-MS)联用技术鉴定粗提物中的抑菌物质。结果表明,絮凝法最适用于贝莱斯芽胞杆菌菌株ZF145发酵上清液中抑菌物质的提取,通过絮凝法提取的粗提物对扁桃假单胞菌流泪致病变种的抑菌圈直径达到19.50 mm,对黄瓜角斑病的盆栽防治效果为42.85%,且粗提物中的主要抑菌物质为C_(13)~C_(16)的surfactin同系物,浓度和纯度均为最高,分别为2.77 g/L和69.28%。表明本研究优化的絮凝法可用于芽胞杆菌发酵液中抑菌物质的提取。

关键词：贝莱斯芽胞杆菌黄瓜角斑病絮凝法防治效果抑菌物质

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2004-2005我国对外贸易形势回顾及展望

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世界贸易组织动态与研究（上海对外贸易学院学报） 2005年第2期12卷 14-17页

作者：谢艳霞天津财经大学国际经济贸易系

在全球经济回暖趋势下,2004年我国对外贸易进一步发展。本文回顾了2004年前三季度外贸状况,同时分析了当前国际国内形势,对2005年中国对外贸易运行态势进行了初步判断。最后提出了今后外贸发展应注意的问题。

关键词：运行态势中国对外贸易外贸发展全球经济中国国内形势趋势国际状况判断

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聚乙烯醇修饰Sb_2O_3/氯丁胶乳复合材料的制备及其分散稳定性

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复合材料学报 2018年第9期35卷 2535-2541页

作者：谢艳霞毕松梅王东强马明明吴飞安徽工程大学纺织服装学院芜湖241000

制备水基亚微米Sb_2O_3浆液,用聚乙烯醇(PVA)作空间稳定剂对Sb_2O_3表面修饰后,与氯丁胶乳(CRL)复合制备一种阻燃的PVA修饰Sb_2O_3/CRL(Sb_2O_3-PVA/CRL)复合材料。探究了最优修饰工艺及其对Sb_2O_3-PVA/CRL分散稳定性的影响规律,从粒... 详细信息

制备水基亚微米Sb_2O_3浆液,用聚乙烯醇(PVA)作空间稳定剂对Sb_2O_3表面修饰后,与氯丁胶乳(CRL)复合制备一种阻燃的PVA修饰Sb_2O_3/CRL(Sb_2O_3-PVA/CRL)复合材料。探究了最优修饰工艺及其对Sb_2O_3-PVA/CRL分散稳定性的影响规律,从粒径分布、FTIR和DTA-TGA等角度探讨PVA修饰明显提升Sb_2O_3分散稳定性的作用机制。结果表明,研钵研磨使Sb_2O_3粒径微细化,是制备亚微米Sb_2O_3的有效手段;PVA修饰Sb_2O_3粉末在3 447cm-1处的—OH伸缩振动特征峰减弱,1 091cm-1处的C—O特征吸收峰消失,推测化学键力是PVA包覆Sb_2O_3粉末的重要方式;获得最优分散稳定性的修饰工艺为:PVA与Sb_2O_3质量比为2%、反应温度为90℃、反应时间为30min;采用最优修饰工艺制备的Sb_2O_3-PVA/CRL复合材料静置6h内有好的分散稳定性。

关键词：胶乳复合材料亚微米Sb2O3 PVA修饰分散稳定性

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