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Journal of Environmental Science and Engineering 2010年第12期4卷 12-17页

作者： L. Rodriguez vazquez H. Ferman Avila E. Torres Carrillo L. Shenz Macias J. Luna Carrete E. Herrera G.GonzSlez D. Aranda Caro J. Carrillo L. Lozoya lnstituto Tecnologico de Parral Avenida Tecnologico # 57 33860 Parral Chihuahua Mexico Centro de Investigacion en Materiales Avanzados （CIMAV） Miguel de Cervantes # 120 31109 Complejo Industrial Chihuahua Chihuahua. Chihuahua Mexico

During the 17th Century, Parral City in the Chihuahua State in Mexico was one of the most important miner zones in the whole world. After more than three centuries important amounts of residuals, known as tailings, with high contents of heavy metals were generated. These residuals are a potential risk for the environment and human health. Given to that, it decided to carry out the analysis of the concentrations of cadmium, lead, chromium, zinc and arsenics, in topsoil samples susceptible of airborne transport and accumulation in risky zones （populated areas）. A 120 kin： area was selected, this include Parral City and its surroundings. From this area 30 samples were obtained. For this purpose, Atomic Absorption Spectroscopy technique was used, expecting high concentrations of heavy metals, above the permit limits, since several studies carried out in the same region, as in San Francisco del Oro Chihuahua, show that the concentrations of all the elements sampled, in topsoil, were above the limits. The analysis in the space distribution of the heavy metal detected will allow us to set the points with the highest susceptibility to the accumulation of those pollutants and to propose mitigation measures and control.

关键词： Heavy metals mining activity topsoil

Viral Entry of Chikungunya Virus

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Viral Entry of Chikungunya Virus

Safety of biologic therapies during pregnancy in women with rheumatic disease

中国生物工程学会第十三届学术年会暨2019年全国生物技术大会

作者：宋豪 Zhennan Zhao Yan Chai Xiyue Jin Changyao Li Fei Yuan Sheng Liu Leonardo vazquez Carlos M. Morel Jinghua Yan Yi Shi Jianxun Qi Feng Gao George F Gao 中国科学院北京生命科学研究院 CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of Microbiology Chinese Academy of Sciences National Institute of Science and Technology for Innovation on Diseases of NeglectedPopulations (INCT-IDPN) Center for Technological Development in Health (CDTS) Oswaldo CruzFoundation (Fiocruz) Rio de Janeiro Institute of Genetics and Developmental Biology Chinese Academy of Sciences Research Network of Immunity and Health (RNIH) Beijing Institutes of Life Science Chinese Academy of Sciences National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention (China CDC)

Arthritogenic alphaviruses, such as Chikungunya virus(CHIKV), Ross River virus(RRV), Mayaro virus(MAYV), and O’nyong-nyong virus(ONNV), cause severe and debilitating rheumatic diseases worldwide, resulting in severe ...

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World Journal of Rheumatology 2015年第2期5卷 82-89页

作者： Natalia Mena-vazquez Sara Manrique-Arija Antonio Fernandez-Nebro Department of Rheumatology Instituto de Investigación Biomédica de Málaga (IBIMA)Hospital Regional Universitario de MálagaUniversidad de Málaga

Inflammatory rheumatic diseases frequently affect women of childbearing *** therapy during pregnancy is an important topic that is yet *** majority of documented experiences are in case series,case reports,or *** necrosis factor(TNF) inhibitors are now better *** evidence suggests that it is possible that differences between drugs regarding safety are associated with the structure and capacity to cross the placenta,but we are not aware of any study that supports unequivocally this *** of the monoclonal antibodies are actively transferred to fetal circulation using the neonatal Fc *** this transfer does not appear to be associated with the risk of miscarriage,stillbirth,or congenital abnormality,the rate of premature births and lower birth weight may be *** fetal development,the neonatal period,and childhood,the immune system is constantly *** ability to produce cytokines in response to infectious stimulus remains low for years,but is similar to that of an adult around the age of 3 years owing to the adaptive nature of the newborn's immune system as a result of exposure to ***,exposure to TNF inhibitors may have serious consequences on the newborn,such as severe infections or allergic *** the former,an anecdotal case report described a fatal case of disseminated bacillus Calmette-Guérin(BCG) infection in an infant born to a mother taking infliximab for Crohn's *** the baby was born and progressed well initially,he died at 4.5 mo after he was vaccinated with ***,serious infections do not appear to be frequent in newborns exposed to in utero biologic ***,very limited short-term experiences are available regarding complications in an exposed fetus,and no data are available about long-term implications on the child's developing immune ***,we must be aware of potential complications in later ***

关键词： Pregnancy Biologic therapy Monoclonal antibodies Rheumatic diseases Safety

Higher cardiovascular risk scores and liver fibrosis risk estimated by biomarkers in patients with metabolic-dysfunction-associated fatty liver disease

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World Journal of Hepatology 2022年第8期14卷 1633-1642页

作者： Giovanni Alejandro Salgado Alvarez Samanta Mayanin Pinto Galvez Uriel Garcia Mora Ana Delfina Cano Contreras Cristina Durán Rosas Bryan Adrián Priego-Parra Arturo Triana Romero Mercedes Amieva Balmori Federico Roesch Dietlen Sophia Eugenia Martinez vazquez Ines Osvely Mendez Guerrero Luis Alberto Chi-Cervera Raúl Bernal Reyes Leonardo Alberto Martinez Roriguez Maria Eugenia Icaza Chavez Jose Maria Remes Troche Instituto de Investigaciones Médico-biologicas Universidad VeracruzanaVeracruz 91700VeracruzMexico Department of Gastroenterología Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMéxico 14080MéxicoMexico Clínica de Especialidades Gastrointestinales y Hepáticas Hospital Star MedicaMerida 97133YucatanMexico Department of Gastroenterologia Sociedad Española de BeneficenciaPachuca 42000HidalgoMexico Department of Gastroenterologia Clínica de Rehabilitación Metabólica Digestiva y HepáticaMexico 14080MexicoMexico Department of Gastroenterologia Hospital Star Médica de MéridaMerida 97133YucatanMexico

BACKGROUND The definition of metabolic-dysfunction-associated fatty liver disease(MAFLD)allows identification of metabolically complicated *** risk scores are related to cardiovascular risk(CVR)scores and could be useful for the identification of patients at risk of systemic *** To evaluate the relationship between MAFLD and CVR using the Framingham risk score in a group of Mexican *** Cross-sectional,observational and descriptive study carried out in a cohort of 585 volunteers in the state of Veracruz with MAFLD *** risk of liver fibrosis was calculated with aspartate aminotransferase-to-platelet ratio index,nonalcoholic fatty liver disease score and fibrosis-4,as well as with transient hepatic elastography with Fibroscan~?.The CVR was determined by the Framingham *** One hundred and twenty-five participants(21.4%)with MAFLD criteria were evaluated,average age 54.4 years,63.2%were women,body mass index 32.3 kg/m~*** Framingham CVR was high in 43 patients(33.9%).Transient elastography was performed in 55.2%of volunteers;39.1%with high CVR and predominance in advanced fibrosis(F3–F4).The logistic regression analysis showed that liver fibrosis,diabetes and hypertension independently increased *** One of every three patients with MAFLD had a high CVR,and in those with high fibrosis risk,the CVR risk was even greater.

关键词： Fatty liver Cardiovascular risk Hepatic steatosis Fibrosis Liver disease

Composition of Triacylglycerols in Fats of Cow and Goat Milk Produced in Four Zones of Mexico

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Food and Nutrition Sciences 2015年第6期6卷 555-561页

作者： Rey Gutié rrez Tolentino Salvador Vega y Leó n Mario Noa Pé rez Marta Coronado Herrera Acacia Ramí rez Ayala José Jesús Pé rez González Beatriz Schettino Bermúdez Rutilio Ortiz Salinas Marcela vazquez Francisca Juan Gabriel Rivera Martí nez Departamento de Producció n Agrí cola y Animal Universidad Aut&oacute noma Metropolitana-Xochimilco M&eacute xico D.F. M&eacute xico Departamento de Salud Pública Universidad de Guadalajara Guadalajara M&eacute xico Maestrí a en Ciencias Agropecuarias Universidad Aut&oacute noma Metropolitana-Xochimilco M&eacute xico D.F. M&eacute xico Departamento de Biologí a de la Reproducció n Universidad Aut&oacute noma Metropolitana-Iztapalapa M&eacute xico D.F. M&eacute xico

The study of the triacylglycerols (TAG) by gas chromatography (GC) using capillary columns is an efficient technique for the determination of some characteristics of quality of fats and oils. The objective of the present study was to determine by GC the content of TAG present in fat of cow and goat milk produced in four zones of Mexico. According to criteria established in Mexican Standardization, 25 samples were obtained of 1 L of ultra-pasteurized cow milk (UHT) and 27 and 48 of raw cow and goat milk, respectively. The fat was extracted from all of the milk samples by detergent solution, and was stored at –20℃ until its analysis. The chromatographic conditions made it possible to identify and quantify TAG of 28 to 54 numbers of carbons, which were analyzed under descriptive and inferential statistical techniques. For the cow milk fat, the statistical analyses indicated significant difference (p < 0.05) in the TAG C34, C50 and C52, and for the goat milk fat in the TAG of C36 to C52. No equality of means was found among the TAG of the cow and goat milk fat. This study offers an advance in the characterization of the TAG present in the cow and goat milk fat produced in Mexico.

关键词： Cow Milk Goat Milk Mexico Triacylglycerols

Comparison of Self-levelling Underlayment to Traditional Methods Used in Brazil

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Journal of Civil Engineering and Architecture 2019年第6期13卷 373-380页

作者： Guilherme Figliuzzi Elaine vazquez Justino Nobrega Joao dos Santos Lais Alves Department of Civil Engineering Federal Center of Technological Education Celso Suckow da FonsecaBrazil Department of Civil Construction Federal University of Rio de JaneiroRio de JaneiroRJ21941-909Brazil DVSST Department Post Graduate Studies on Safety EngineeringFederal University of Rio de JaneiroRio de JaneiroRJ21941-909Brazil Department of Civil Engineering Federal Center of Technological Education Celso Suckow da FonsecaBrazil Department of Civil Engineering Federal Center of Technological Education Celso Suckow da FonsecaRio de JaneiroRJ20271-110Brazil

Between 2005 and 2015,the Brazilian real estate market experienced strong growth,driven by the stable scenario of the Brazilian economy and policies to encourage real estate *** this demand,the companies of the sector sought to be more competitive in the *** of the measures adopted is the search for more efficient executive *** the traditional manual methodology for underlayment predominates in the country’s construction sites,a self-levelling underlayment presents a tendency towards mechanization of executive construction *** paper aims to present a case study of a residential construction in Rio de Janeiro,which used self-levelling underlayment *** regarding cost and productivity of both methodologies were made to evaluate the viability of the self-levelling underlayment in future construction *** obtained from other constructions were used to estimate the productivity and cost of the traditional underlayment *** results demonstrate that the use of self-levelling underlayment has potential to be widespread and used in the constructions in Brazil.

关键词： Traditional levelling underlayment self-levelling underlayment cost productivity

Microcellular Agave Fibre-High Density Polyethylene Composites Produced by Injection Molding

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材料科学与工程（中英文A版） 2012年第11期2卷 677-692页

作者： Cedric Tissandier Roberto Carlos vazquez Fletes Ruben Gonzalez-Nunez Denis Rodrigue Departement de Genie Chimique Universite Laval Quebec G1 V OA6 Canada Departamento de Ingenierla Quimica Universidad de Guadalajara Guadalajara 44430 Mexico

In this study, microcellular high density polyethylene-agave fibre composites were produced using a chemical foaming agent (azodicarbonamide). The samples were injection molded with the objective to produce symmetric and asymmetric structures. To this end, the temperatures of both parts of the mold were independently controlled. From the samples produced, a complete morphological and mechanical characterization was performed. As expected, composite density increased with fibre content and decreased with foaming agent content. Young"s modulus was found to increase, but strain at break decreased with increasing agave content. Moreover, Young"s modulus and strain at break both decreased with increasing foaming agent content. Actually, the microcellular foams were found to have a different tensile behavior than their natural fibre-reinforced counterparts. Considering the experimental results obtained, natural fibre-reinforced microcellular foams present interesting properties for different technical applications.

关键词：聚乙烯复合材料高密度聚乙烯纤维复合材料微孔泡沫龙舌兰生产注塑天然纤维增强

Risk Groups and Mortality in Patients with SARS-CoV-2 from Family Medicine Unit No. 43 in Southeastern Mexico

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Journal of Biosciences and Medicines 2023年第1期11卷 116-122页

作者： Abel Pérez-Pavón Sigrid Lorena Martínez-vazquez Jorge Iván Martínez-Pérez Jorda Aleiria Albarrán-Melzer Juan Antonio Córdova-Hernández Sergio De Jesús Romero-Tapia Sergio Quiroz-Gomez Crystell G. Guzmán-Priego Social Security Institute of the State of Tabasco Villahermosa Mexico Cardiometabolism Laboratory Academic Division of Health Sciences Juarez Autonomous University of Tabasco Villahermosa México

SARS-CoV-2 infection is a viral disease that causes respiratory infections that can cause multiple complications. Patients with adjacent morbidities have a higher chance of complications and mortality. The National Health and Nutrition Survey (ENSANUT) in 2018 reported that in Mexico, 75.2% of adults aged 20 years and over are overweight and obese, both situations are closely related to the cases reported as severe COVID and even with a higher risk of mortality. The main objective was to evaluate the risk and mortality groups in patients with SARS-CoV-2 from family medicine in the south of México. The study was carried out during the 2020 year, in the Family Medicine Unit No. 43 of Villahermosa, Tabasco, a cross-sectional, retrospective investigation was carried out with an analytical approach, and the sample was obtained using the formula of n for infinite populations that correspond to 215, patients were included who met the selection criteria;3 groups were integrated: DM2, HAS and obesity. Descriptive statistics andχ2 formula were used, using the SPSS version 25 Windows program. The female gender presented the highest number of infections 122 (56.7%) and mortality: 5 (2.32%), obesity comorbidity presented the highest number of infections: 194 (90.2%), HAS: 153 (71.2%), and MD: 44 (20.46%). Complications were observed in 23 (10.69%), distributed in: SIRA: 7 (3.3%), multiple organ failure: 6 (2.8%), heart failure: 6 (2.8%) and pneumonia 4 (1.9%). The observed mortality was 8 (3.72%). The comorbidities of patients with the highest mortality were: SAH: 6 (75%) (χ2 = 9.169;df = 1;p = 0.010) and obesity: 6 (75%) (χ2 = 9.169;df = 1;p = 0.010). The group with the highest risk for SARS-CoV-2 was patients with overweight/obesity comorbidities. Mortality was 3.7%. The patients who died had at least one or more comorbidities. The main complications were ARIS, heart failure, and multiple organ failure.

关键词： Pandemic COVID-19 SARS-CoV-2 Hypertension Diabetes Obesity Mortality

Apixaban, an orally available anticoagulant, inhibits SARS-CoV-2 replication and its major protease in a non-competitive way

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Journal of Molecular Cell Biology 2022年第6期14卷 68-71页

作者： Otávio Augusto Chaves Carolina Q.Sacramento Natalia Fintelman-Rodrigues Jairo Ramos Temerozo Filipe Pereira-Dutra Daniella M.Mizurini Robson Q.Monteiro Leonardo vazquez Patricia T.Bozza Hugo Caire Castro-Faria-Neto Thiago Moreno L.Souza Laboratory of Immunopharmacology Oswaldo Cruz Institute(IOC)Oswaldo Cruz Foundation(Fiocruz)Rio de JaneiroRJ21040-900Brazil National Institute for Science and Technology on Innovation on Neglected Diseases(INCT/IDN) Center for Technological Development in Health(CDTS)Oswaldo Cruz Foundation(Fiocruz)Rio de JaneiroRJ21040-900Brazil National Institute for Science and Technology on Neuroimmunomodulation(INCT/NIM) Oswaldo Cruz Institute(IOC)Oswaldo Cruz Foundation(Fiocruz)Rio de JaneiroRJ21040-900Brazil Laboratory on Thymus Research Oswaldo Cruz Institute(IOC)Oswaldo Cruz Foundation(Fiocruz)Rio de JaneiroRJ21040-900Brazil Institute of Medical Biochemistry Leopoldo de Meis Federal University of Rio de Janeiro(UFRJ)Rio de JaneiroRJ21941-590Brazil

Dear Editor,The severe coronavirus disease 2019(COVID-19)is associated with ***,such as low-molecular-weight heparin,warfarin,thrombin inhibitors,and factor Xa(FXa)inhibitors,are thus recommended by the American Society of Hematology and National Institutes of Health for COVID-19 patients(Wenzler et al.,2020;Adam et al.,2021).Clinical trials with anticoagulants have shown the increased survival of critically ill COVID-19 patients under non-invasive and invasive ventilatory assistance(Wenzler et al.,2020;Adam et al.,2021),along with decreased consumption of platelets and clotting factors and a reduced risk of hemorrhage(Adam et al.,2021).Among the anti-clotting agents,early use of orally available FXa and thrombin inhibitors(Chowdhury et al.,2020;Rentsch et al.,2021)prevented high levels of D-dimer,which is the final product from the clotting/fibrinolysis cascade and is directly implicated with severe COVID-19(Rentsch et al.,2021).

关键词： al. Clinical heparin