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Facile Semiconductor p-n Homojunction Nanowires with Strategic p-Type Doping Engineering Combined with Surface Reconstruction for Biosensing Applications

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Nano-Micro Letters 2024年第10期16卷 15-30页

作者： Liuan Li Shi Fang Wei Chen Yueyue Li Mohammad Fazel Vafadar Danhao Wang Yang Kang Xin Liu Yuanmin Luo Kun Liang Yiping dang Lei Zhao Songrui Zhao Zongzhi Yin Haiding Sun iGaN Laboratory School of MicroelectronicsUniversity of Science and Technology of ChinaHefei 230026People's Republic of China Department of Obstetrics and Gynecology The First Affiliated Hospital of Anhui Medical UniversityNo 218 Jixi RoadHefei 230022People's Republic of China Department of Electrical and Computer Engineering McGill University3480 University StreetMontrealQC H3A 0E9Canada Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyNo 1277 Jiefang Ave.Wuhan 430022People's Republic of China

Photosensors with versatile functionalities have emerged as a cornerstone for breakthroughs in the future optoelectronic systems across a wide range of *** particular,emerging photoelectrochemical(PEC)-type devices have recently attracted extensive interest in liquid-based biosensing applications due to their natural electrolyte-assisted operating ***,a PEC-type photosensor was carefully designed and constructed by employing gallium nitride(GaN)p-n homojunction semiconductor nanowires on silicon,with the p-GaN segment strategically doped and then decorated with cobalt-nickel oxide(CoNiO_(x)).Essentially,the p-n homojunction configuration with facile p-doping engineering improves carrier separation efficiency and facilitates carrier transfer to the nanowire surface,while CoNiO_(x)decoration further boosts PEC reaction activity and carrier dynamics at the nanowire/electrolyte ***,the constructed photosensor achieves a high responsivity of 247.8 mA W^(-1)while simultaneously exhibiting excellent operating ***,based on the remarkable stability and high responsivity of the device,a glucose sensing system was established with a demonstration of glucose level determination in real human *** work offers a feasible and universal approach in the pursuit of high-performance bio-related sensing applications via a rational design of PEC devices in the form of nanostructured architecture with strategic doping engineering.

关键词： p-n GaN nanowires Strategic p-doping Surface decoration Photoelectrochemical sensor Glucose sensing

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迈向高质量的社区志愿服务:发展机遇、现实困境与未来趋势

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中国行政管理 2024年第2期40卷 65-75页

作者：党秀云中央民族大学管理学院北京100081

作为社区治理与创新中的一支重要力量,社区志愿服务在引领社区文明实践,补齐社区服务短板、维护社区和谐稳定等方面扮演着重要角色并发挥着积极作用。推动社区志愿服务高质量发展,打造与新时代发展要求相符合的社区志愿服务体系,已经成... 详细信息

作为社区治理与创新中的一支重要力量,社区志愿服务在引领社区文明实践,补齐社区服务短板、维护社区和谐稳定等方面扮演着重要角色并发挥着积极作用。推动社区志愿服务高质量发展,打造与新时代发展要求相符合的社区志愿服务体系,已经成为构建现代化社区治理的重要内容。随着基层社会治理的转型升级,社区志愿服务迎来了前所未有的良好发展机遇,但也面临着更高的要求与挑战。立足高质量发展的时代要求,推动社区志愿服务的制度化、常态化、专业化、标准化、项目化、智慧化,就成为一种发展趋势。

关键词：社区志愿服务发展机遇现实困境未来趋势

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Research on Iron Loss of Switched Reluctance Starter/Generator for Energy Storage

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Protection and Control of Modern Power Systems 2024年第4期9卷 147-159页

作者： Hao Chen Xing Wang Yongqiang Liu Vuong dang Quoc Wenju Yan Muhammad Saqib Antonino Musolino Guanjun Wang Yong Qi Ali Asghar Memon Alexandros G.Paspatis the Shenzhen Research Institute China University of Mining and TechnologyShenzhen 515100China the School of Electrical Engineering China University of Mining and TechnologyXuzhou 221116China Xinjiang Institute of Engineering Urumqi 830000China the International Joint Research Center of Central and Eastern European Countries on New Energy EV Technology and Equipment Xuzhou 221008China the International Cooperation Joint Laboratory of New Energy Power Generation and EVs of Jiangsu Province Colleges and Universities Xuzhou 221008China the Xuzhou Key Laboratory of New Energy EV Technology and Equipment Xuzhou 221008China the the School of Electrical Engineering China University of Mining and Tech-nologyXuzhou 221116China the Laboratory of High Performance Electric Machines(HiPems) Hanoi VN 10000Viet Nam the University of Engineering and Technology Lahore 54890Pakistan the Department of Energy Pisa Uni-versity of PisaPisa IT 56126Italy the Wuxi Inspection and Testing Certification Research Institute Wuxi 214000China the Nanjing University of Science&Tech-nology Nanjing 210094China the Mehran University of Engi-neering&Technology Jamshoro PK 76062Sindh the National Technical University of Athens Zografou GR 15780Attica

In order to better realize the energy recovery and storage of hybrid EVs(HEVs),a switched reluctance starter/generator(SRS/G)with both starting and power generation functions is investigated in this ***,the iron loss of SRS/G is mainly studied to reduce the motor loss and improve the power generation ***,the energy storage of hybrid EVs can be effectively ***,a magnetic flux density(MFD)waveforms solution method is proposed to solve the difficulty in calculating the iron loss of the SRS/*** with the commonly used finite element method,the proposed solution method has the advantages of simple,fast and small computational ***,considering the different operating conditions of SRS/G,the iron loss models for both the time-domain and frequency-domain are *** addition,the calculation formula of the variable coefficient Bertotti three-term loss separation is *** the hysteresis loss coefficient,the Steinmetz coefficient and the stray loss coefficient are respectively fitted by the Fourier fitting *** method is also applied to solve the iron loss of SRS/***,through an experimental verification,it is indicated that the development of proposed method has high accuracy.

关键词： Switched reluctance starter/generator energy storage iron loss finite element method magnetic flux density(MFD)

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Efficient solar-driven CO_(2)-to-fuel conversion via Ni/MgAlO_(x)@SiO_(2)nanocomposites at low temperature

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Fundamental Research 2024年第1期4卷 131-139页

作者： Xianglei Liu Yueyue Ling Chen Sun Hang Shi Hangbin Zheng Chao Song Ke Gao Chunzhuo dang Nan Sun Yimin Xuan Yulong Ding School of Energy and Power Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China Birmingham Centre for Energy Storage School of Chemical EngineeringUniversity of BirminghamBirmingham B152TTUnited Kingdom

Solar-driven CO_(2)-to-fuel conversion assisted by another major greenhouse gas CH_(4)is promising to concurrently tackle energy shortage and global warming ***,current techniques still suffer from drawbacks of low efficiency,poor stability,and low ***,a novel nanocomposite composed of interconnected Ni/MgAlOx nanoflakes grown on SiO_(2)particles with excellent spatial confinement of active sites is proposed for direct solar-driven CO_(2)-to-fuel *** ultrahigh light-to-fuel efficiency up to 35.7%,high production rates of H_(2)(136.6 mmol min^(-1)g^(-1))and CO(148.2 mmol min^(-1)g^(-1)),excellent selectivity(H_(2)/CO ratio of 0.92),and good stability are reported *** outstanding performances are attributed to strong metal-support interactions,improved CO_(2)absorption and activation,and decreased apparent activation energy under direct light ***_(x)@SiO_(2)support helps to lower the activation energy of CH^(*) oxidation to CHO^(*) and improve the dissociation of CH_(4)to CH_(3)^(*) as confirmed by DFT ***,the lattice oxygen of MgAlO_(x) participates in the reaction and contributes to the removal of carbon *** work provides promising routes for the conversion of greenhouse gasses into industrially valuable syngas with high efficiency,high selectivity,and benign sustainability.

关键词： Solar fuel CO_(2)reduction Dry reforming of methane Photothermocatalysis Stability

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miR-125b reverses cisplatin resistance by regulating autophagy via targeting RORA/BNIP3L axis in lung adenocarcinoma

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Oncology Research 2024年第4期32卷 643-658页

作者： LEI LIU NA GUO XIANGLING LI QIAN XU RUILONG HE LIMIN CHENG CHUNYAN dang XINYU BAI YIYING BAI XIN WANG QIANHUI CHEN LI ZHANG Department of Immunology Chengde Medical UniversityChengde067000China Department of Pathology Chengde Medical UniversityChengde067000China Department of Oncology The Affiliated Hospital of Chengde Medical UniversityChengde067000China Department of Hepatobiliary Surgery The Affiliated Hospital of Chengde Medical UniversityChengde067000China

The platinum-based chemotherapy is one of the most frequently used treatment protocols for lung adenocarcinoma(LUAD),and chemoresistance,however,usually results in treatment failure and limits its application in the *** has been shown that microRNAs(miRNAs)play a significant role in tumor *** this study,miR-125b was identified as a specific cisplatin(DDP)-resistant gene in LUAD,as indicated by the bioinformatics analysis and the real-time quantitative PCR *** decreased serum level of miR-125b in LUAD patients was correlated with the poor treatment response rate and short survival ***-125b decreased the A549/DDP proliferation,and the multiple drug resistance-and autophagy-related protein expression levels,which were all reversed by the inhibition of *** addition,xenografts of human tumors in nude mice were suppressed by miR-125b,demonstrating that through autophagy regulation,miR-125b could reverse the DDP resistance in LUAD cells,both in vitro and in *** mechanistic studies indicated that miR-125b directly repressed the expression levels of RORA and its downstream BNIP3L,which in turn inhibited autophagy and reversed *** on these findings,miR-125b in combination with DDP might be an effective treatment option to overcome DDP resistance in LUAD.

关键词： Lung adenocarcinoma miRNAs Cisplatin Resistance Autophagy

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Nitrite-driven anaerobic ethane oxidation

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Environmental Science and Ecotechnology 2024年第5期21卷 361-368页

作者： Cheng-Cheng dang Yin-Zhu Jin Xin Tan Wen-Bo Nie Yang Lu Bing-Feng Liu De-Feng Xing Nan-Qi Ren Guo-Jun Xie State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090China Key Laboratory of the Three Gorges Region's Eco-Environment Ministry of EducationCollege of Environment and EcologyChongqing UniversityChongqing400044China Water Innovation and Smart Environment Laboratory School of Civil and Environmental EngineeringFaculty of EngineeringQueensland University of TechnologyBrisbaneQueensland4001Australia

Ethane,the second most abundant gaseous hydrocarbon in vast anoxic environments,is an overlooked greenhouse *** anaerobic oxidation of ethane can be driven by available electron acceptors such as sulfate and ***,despite nitrite being a more thermodynamically feasible electron acceptor than sulfate or nitrate,little is known about nitrite-driven anaerobic ethane *** this study,a microbial culture capable of nitrite-driven anaerobic ethane oxidation was enriched through the long-term operation of a nitrite-and-ethane-fed *** continuous operation,the nitrite removal rate and the theoretical ethane oxidation rate remained stable at approximately 25.0 mg NO_(2) eN L^(-1) d^(-1) and 11.48 mg C2H6 L^(-1) d^(-1),*** tests demonstrated that ethane is essential for nitrite removal in this microbial *** function analysis revealed that a species affiliated with a novel genus within the family Rhodocyclaceae,designated as'Candidatus Alkanivoras nitrosoreducens',may perform the nitrite-driven anaerobic ethane *** the proposed metabolic model,despite the absence of known genes for ethane conversion to ethyl-succinate and succinate-CoA ligase,'***'encodes a prospective fumarate addition pathway for anaerobic ethane oxidation and a complete denitrification pathway for nitrite reduction to *** findings advance our understanding of nitrite-driven anaerobic ethane oxidation,highlighting the previously overlooked impact of anaerobic ethane oxidation in natural ecosystems.

关键词： Anaerobic ethane oxidation Denitrification Microbial culture Fumarate addition pathway Greenhouse gas

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Targeted anti-cancer therapy: Co-delivery of VEGF siRNA and Phenethyl isothiocyanate (PEITC) via cRGD-modified lipid nanoparticles for enhanced anti-angiogenic efficacy

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Asian Journal of Pharmaceutical Sciences 2024年第2期19卷 170-187页

作者： Bao Li Haoran Niu Xiaoyun Zhao Xiaoyu Huang Yu Ding Ke dang Tianzhi Yang Yongfeng Chen Jizhuang Ma Xiaohong Liu Keda Zhang Huichao Xie Pingtian Ding School of Pharmacy Shenyang Pharmaceutical UniversityShenyang 110016China School of Life Science and Biopharmaceutics Shenyang Pharmaceutical University Shenyang 110016 China Department of Basic Pharmaceutical Sciences School of Pharmacy Husson University Bangor ME 04401USA College of Pharmacy Shenzhen Technology UniversityShenzhen 518118China

Anti-tumor angiogenesis therapy, targeting the suppression of blood vessel growth in tumors, presents a potent approach in the battle against cancer. Traditional therapies have primarily concentrated on single-target techniques, with a specific emphasis on targeting the vascular endothelial growth factor, but have not reached ideal therapeutic efficacy. In response to this issue, our study introduced a novel nanoparticle system known as CS-siRNA/PEITC&L-cRGD NPs. These chitosan-based nanoparticles have been recognized for their excellent biocompatibility and ability to deliver genes. To enhance their targeted delivery capability, they were combined with a cyclic RGD peptide (cRGD). Targeted co-delivery of gene and chemotherapeutic agents was achieved through the use of a negatively charged lipid shell and cRGD, which possesses high affinity for integrin αvβ3 overexpressed in tumor cells and neovasculature. In this multifaceted approach, co-delivery of VEGF siRNA and phenethyl isothiocyanate (PEITC) was employed to target both tumor vascular endothelial cells and tumor cells simultaneously. The co-delivery of VEGF siRNA and PEITC could achieve precise silencing of VEGF, inhibit the accumulation of HIF-1α under hypoxic conditions, and induce apoptosis in tumor cells. In summary, we have successfully developed a nanoparticle delivery platform that utilizes a dual mechanism of action of anti-tumor angiogenesis and pro-tumor apoptosis, which provides a robust and potent strategy for the delivery of anti-cancer therapeutics.

关键词： Anti-angiogenesis Tumor apoptosis Nanoparticles VEGF siRNA Hypoxia inducible factor(HIF)-1 protein Phenethyl isothi ocyanate(PEITC)

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数字经济对全国统一农产品大市场的影响效应分析

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技术经济与管理研究 2024年第4期 39-44页

作者：党军中国社会科学院大学北京102401

选取2013—2022年中国30个省级面板数据,利用双重固定效应模型与空间计量方法实证检验数字经济对全国统一农产品大市场的影响效应。结果表明,数字经济能够显著促进全国统一农产品大市场建设,且二者间关系呈倒“U”型特征;数字经济对全... 详细信息

选取2013—2022年中国30个省级面板数据,利用双重固定效应模型与空间计量方法实证检验数字经济对全国统一农产品大市场的影响效应。结果表明,数字经济能够显著促进全国统一农产品大市场建设,且二者间关系呈倒“U”型特征;数字经济对全国统一农产品大市场建设的推动作用在东部、中部以及东北地区显著,在西部地区不显著;数字经济与全国统一农产品大市场均具有显著正向空间溢出效应;数字经济对本地区全国统一农产品大市场具有直接促进效应,对周边地区产生较强的挤出或竞争效应。

关键词：数字经济全国统一农产品大市场农业高质量发展农村产业结构农业技术进步

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从道德政治走向人类解放:马克思对“卢梭悖论”的超越

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教学与研究 2024年第6期 46-56页

作者：张当中国人民大学马克思主义学院中国人民大学北京高校思想政治理论课高精尖中心北京100872

在对以自然原则为核心的近代政治哲学批判中,卢梭强调现代社会及其不平等关系使人陷入精神贫困之中,并且在重构社会历史理论的过程中指出私有财产是造成贫富矛盾以及奴役状态的主要原因。尽管卢梭着重批判了私有财产权所导致的贫富分化... 详细信息

在对以自然原则为核心的近代政治哲学批判中,卢梭强调现代社会及其不平等关系使人陷入精神贫困之中,并且在重构社会历史理论的过程中指出私有财产是造成贫富矛盾以及奴役状态的主要原因。尽管卢梭着重批判了私有财产权所导致的贫富分化问题,但是他却无法摆脱对私有财产的承认,主张在私有财产权的基础上重建以道德政治为核心的社会,由此形成“卢梭悖论”。在对卢梭政治哲学的继承与批判中,马克思不仅认识到人的异化的深层原因,而且从无产阶级视角阐明道德政治的无效性,进而指出只有通过消灭私有制和重建个人所有制,才能实现人类解放和真正平等的社会关系。这既是马克思对“卢梭悖论”的超越,也是马克思政治哲学的核心要义。

关键词：道德政治人类解放卢梭悖论政治哲学

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High energy storage properties of(Nb_(0.5)La_(0.5))^(4+)complex-ion modified(Ba_(0.85)Ca_(0.15))(Zr_(0.10)Ti_(0.90))O_(3)ceramics

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Journal of Advanced Dielectrics 2024年第4期14卷 51-62页

作者： Yaqiong Sun Santan dang Zhanhui Peng Bi Chen Yibing Zhang Di Wu Pengfei Liang Lingling Wei Xiaolian Chao Zupei Yang Key Laboratory for Macromolecular Science of Shaanxi Province Shaanxi Key Laboratory for Advanced Energy Devices Shaanxi Engineering Laboratory for Advanced Energy Technology School of Materials Science and Engineering Shaanxi Normal University Xi’an 710062ShaanxiP.R.China School of Chemistry and Chemical Engineering Yulin University Yulin 719000ShaanxiP.R.China School of Physics and Information Technology Shaanxi Normal University Xi’an 710062ShaanxiP.R.China School of Chemistry and Chemical Engineering Shaanxi Normal University Xi’an 710062ShaanxiP.R.China

In this work,a traditional solid-state method was adopted to prepare dense Ba_(0.85)Ca_(0.15)[(Zr_(0.1)Ti_(0.9))_(1-x)–(Nb_(0.5)La_(0.5))_(x)]O_(3)(BCZT–xNL)lead-free relaxation ferroelectrics with excellent energy storage performance(ESP).Remarkably,a large breakdown field strength of BDS(-410 kV/cm)resulting from decreased grain size by double ions doping at the B-site was achieved in BCZT–xNL ***,the BCZT–0.12NL ceramic displays a good recoverable energy density(W_(rec))of 3.1 J/cm^(3),a high efficiency of 86.7%(η)and a superior fatigue resistance,as well as a superior charge–discharge performance(C_(D)-1623.14 A/cm^(2),P_(D)-162.31 MW/cm^(3),W_(D)-1.30 J/cm^(3),t_(0.9)-49.6 ns)and good thermal ***,upon NL doping,the FE to RFE phase transition results in a dielectric behavior traversing the relaxation phase(γ1.84)accompanied by frequency dispersion,which is beneficial to improve *** superior ESP in this work indicates that BCZT–0.12NL ceramics are a promising candidate used in energy storage capacitors.

关键词： Co-doped BCZT ceramics relaxor ferroelectric high BDS energy storage

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